Interleukin-11 causes alveolar type 2 cell dysfunction and prevents alveolar regeneration.
Ng B, Huang KY, Pua CJ, Viswanathan S, Lim WW, Kuthubudeen FF, Liu YN, Hii AA, George BL, Widjaja AA, Petretto E, Cook SA., Free PMC Article

Characterization of the angiomodulatory effects of Interleukin 11 cis- and trans-signaling in the retina.
Liang P, Ness J, Rapp J, Boneva S, Schwämmle M, Jung M, Schlunck G, Agostini H, Bucher F., Free PMC Article

Inhibition of IL-11 signalling extends mammalian healthspan and lifespan.
Widjaja AA, Lim WW, Viswanathan S, Chothani S, Corden B, Dasan CM, Goh JWT, Lim R, Singh BK, Tan J, Pua CJ, Lim SY, Adami E, Schafer S, George BL, Sweeney M, Xie C, Tripathi M, Sims NA, Hübner N, Petretto E, Withers DJ, Ho L, Gil J, Carling D, Cook SA., Free PMC Article

Antibody-mediated neutralization of IL11 signalling reduces ERK activation and cardiac fibrosis in a mouse model of severe pressure overload.
Lim WW, Corden B, Ye L, Viswanathan S, Widjaja AA, Xie C, Su L, Tee NGZ, Schafer S, Cook SA.

Mesenchymal stromal cells protect tissues from Th1 immune responses via IL-11 secretion.
Cho WJ, Pulimamidi VK, Mittal SK, Chauhan SK.,

Targeting IL-11 to reduce fibrocyte circulation and lung accumulation in animal models of pulmonary hypertension-associated lung fibrosis.
Milara J, Roger I, Montero P, Artigues E, Escrivá J, Del Río R, Cortijo J.

ALKBH5-mediated m6A modification of IL-11 drives macrophage-to-myofibroblast transition and pathological cardiac fibrosis in mice.
Zhuang T, Chen MH, Wu RX, Wang J, Hu XD, Meng T, Wu AH, Li Y, Yang YF, Lei Y, Hu DH, Li YX, Zhang L, Sun AJ, Lu W, Zhang GN, Zuo JL, Ruan CC., Free PMC Article

Interleukin-11 Suppresses Ocular Surface Inflammation and Accelerates Wound Healing.
Singh A, Cho WJ, Pulimamidi VK, Mittal SK, Chauhan SK., Free PMC Article

Macrophages release IL11-containing filopodial tip vesicles and contribute to renal interstitial inflammation.
Zhu X, Zhao Y, Liu Y, Shi W, Yang J, Liu Z, Zhang X., Free PMC Article

The effect of hepatic stellate cell derived-IL-11 on hepatocyte injury in hepatic fibrosis.
Jiang LF, Yang M, Meng HW, Jia PC, Du CL, Liu JY, Lv XW, Cheng-Huang, Li J.

Cardiomyocyte-Restricted Expression of IL11 Causes Cardiac Fibrosis, Inflammation, and Dysfunction.
Sweeney M, O'Fee K, Villanueva-Hayes C, Rahman E, Lee M, Vanezis K, Andrew I, Lim WW, Widjaja A, Barton PJR, Cook SA., Free PMC Article

IL11 activates the placental inflammasome to drive preeclampsia.
Menkhorst E, Santos LL, Zhou W, Yang G, Winship AL, Rainczuk KE, Nguyen P, Zhang JG, Moore P, Williams M, Lê Cao KA, Mansell A, Dimitriadis E., Free PMC Article

IL11 (Interleukin-11) Causes Emphysematous Lung Disease in a Mouse Model of Marfan Syndrome.
Ng B, Xie C, Su L, Kuthubudeen FF, Kwek XY, Yeong D, Pua CJ, Cook SA, Lim WW., Free PMC Article

IL11 signaling mediates piR-2158 suppression of cell stemness and angiogenesis in breast cancer.
Zhao Q, Qian L, Guo Y, Lü J, Li D, Xie H, Wang Q, Ma W, Liu P, Liu Y, Wang T, Wu X, Han J, Yu Z., Free PMC Article

Neutralization of interleukin-11 attenuates silica particles-induced pulmonary inflammation and fibrosis in vivo.
Ma J, Xie Y, Xu Y, Gu P, Zhang Y, Fan L, Zhou Y, Wang H, Zhou T, He J, Wang D, Chen W.

Osteoblast/osteocyte-derived interleukin-11 regulates osteogenesis and systemic adipogenesis.
Dong B, Hiasa M, Higa Y, Ohnishi Y, Endo I, Kondo T, Takashi Y, Tsoumpra M, Kainuma R, Sawatsubashi S, Kiyonari H, Shioi G, Sakaue H, Nakashima T, Kato S, Abe M, Fukumoto S, Matsumoto T., Free PMC Article

MEK/ERK/RUNX2 Pathway-Mediated IL-11 Autocrine Promotes the Activation of Müller Glial Cells during Diabetic Retinopathy.
Ji N, Guo Y, Liu S, Zhu M, Tu Y, Du J, Wang X, Wang Y, Song E.

Sirt1 overexpression improves senescence-associated pulmonary fibrosis induced by vitamin D deficiency through downregulating IL-11 transcription.
Zhou J, Chen H, Wang Q, Chen S, Wang R, Wang Z, Yang C, Chen A, Zhao J, Zhou Z, Mao Z, Zuo G, Miao D, Jin J., Free PMC Article

IL11 Activates Pancreatic Stellate Cells and Causes Pancreatic Inflammation, Fibrosis and Atrophy in a Mouse Model of Pancreatitis.
Ng B, Viswanathan S, Widjaja AA, Lim WW, Shekeran SG, Goh JWT, Tan J, Kuthubudeen F, Lim SY, Xie C, Schafer S, Adami E, Cook SA., Free PMC Article

Krüppel-Like Factor 15/Interleukin 11 Axis-Mediated Adventitial Remodeling Depends on Extracellular Signal-Regulated Kinases 1 and 2 Activation in Angiotensin II-Induced Hypertension.
Guo YT, Lu YY, Lu X, He S, Li SJ, Shao S, Zhou HD, Wang RQ, Li XD, Gao PJ., Free PMC Article

Similarities and differences between IL11 and IL11RA1 knockout mice for lung fibro-inflammation, fertility and craniosynostosis.
Ng B, Widjaja AA, Viswanathan S, Dong J, Chothani SP, Lim S, Shekeran SG, Tan J, McGregor NE, Walker EC, Sims NA, Schafer S, Cook SA., Free PMC Article

Interleukin-11-expressing fibroblasts have a unique gene signature correlated with poor prognosis of colorectal cancer.
Nishina T, Deguchi Y, Ohshima D, Takeda W, Ohtsuka M, Shichino S, Ueha S, Yamazaki S, Kawauchi M, Nakamura E, Nishiyama C, Kojima Y, Adachi-Akahane S, Hasegawa M, Nakayama M, Oshima M, Yagita H, Shibuya K, Mikami T, Inohara N, Matsushima K, Tada N, Nakano H., Free PMC Article

Fibroblast-specific IL11 signaling drives chronic inflammation in murine fibrotic lung disease.
Ng B, Dong J, Viswanathan S, Widjaja AA, Paleja BS, Adami E, Ko NSJ, Wang M, Lim S, Tan J, Chothani SP, Albani S, Schafer S, Cook SA.

Interleukin-11 is important for vascular smooth muscle phenotypic switching and aortic inflammation, fibrosis and remodeling in mouse models.
Lim WW, Corden B, Ng B, Vanezis K, D'Agostino G, Widjaja AA, Song WH, Xie C, Su L, Kwek XY, Tee NGZ, Dong J, Ko NSJ, Wang M, Pua CJ, Jamal MH, Soh B, Viswanathan S, Schafer S, Cook SA., Free PMC Article

Roles of interleukin-11 during acute bacterial pneumonia.
Traber KE, Dimbo EL, Symer EM, Korkmaz FT, Jones MR, Mizgerd JP, Quinton LJ., Free PMC Article