| Role of HIV-1 Tat Protein Interactions with Host Receptors in HIV Infection and Pathogenesis. | Role of HIV-1 Tat Protein Interactions with Host Receptors in HIV Infection and Pathogenesis.
Cafaro A, Schietroma I, Sernicola L, Belli R, Campagna M, Mancini F, Farcomeni S, Pavone-Cossut MR, Borsetti A, Monini P, Ensoli B., Free PMC Article | 02/23/2024 |
| Chronic HIV-1 Tat action induces HLA-DR downregulation in B cells: A mechanism for lymphoma immune escape in people living with HIV. | Chronic HIV-1 Tat action induces HLA-DR downregulation in B cells: A mechanism for lymphoma immune escape in people living with HIV.
Shmakova A, Hugot C, Kozhevnikova Y, Schwager Karpukhina A, Tsimailo I, Gérard L, Boutboul D, Oksenhendler E, Szewczyk-Roszczenko O, Roszczenko P, Buzun K, Sheval EV, Germini D, Vassetzky Y. | 02/1/2024 |
| HIV-1 Tat Induces Dysregulation of PGC1-Alpha and Sirtuin 3 Expression in Neurons: The Role of Mitochondrial Biogenesis in HIV-Associated Neurocognitive Disorder (HAND). | HIV-1 Tat Induces Dysregulation of PGC1-Alpha and Sirtuin 3 Expression in Neurons: The Role of Mitochondrial Biogenesis in HIV-Associated Neurocognitive Disorder (HAND).
Figarola-Centurión I, Escoto-Delgadillo M, González-Enríquez GV, Gutiérrez-Sevilla JE, Vázquez-Valls E, Cárdenas-Bedoya J, Torres-Mendoza BM., Free PMC Article | 01/11/2024 |
| A truncated HIV Tat demonstrates potent and specific latency reversal activity. | A truncated HIV Tat demonstrates potent and specific latency reversal activity.
Van Gulck E, Pardons M, Nijs E, Verheyen N, Dockx K, Van Den Eynde C, Battivelli E, Vega J, Florence E, Autran B, Archin NM, Margolis DM, Katlama C, Hamimi C, Van Den Wyngaert I, Eyassu F, Vandekerckhove L, Boden D., Free PMC Article | 12/29/2023 |
| PRMT2 promotes HIV-1 latency by preventing nucleolar exit and phase separation of Tat into the Super Elongation Complex. | PRMT2 promotes HIV-1 latency by preventing nucleolar exit and phase separation of Tat into the Super Elongation Complex.
Jin J, Bai H, Yan H, Deng T, Li T, Xiao R, Fan L, Bai X, Ning H, Liu Z, Zhang K, Wu X, Liang K, Ma P, Gao X, Hu D., Free PMC Article | 11/14/2023 |
| HIV-1 Transcriptional Activator Tat Inhibits IL2 Expression by Preventing the Presence of Pol II on the IL2 Promoter. | HIV-1 Transcriptional Activator Tat Inhibits IL2 Expression by Preventing the Presence of Pol II on the IL2 Promoter.
Anastasopoulou S, Georgakopoulos T, Mouzaki A., Free PMC Article | 07/5/2023 |
| A Tripartite Complex HIV-1 Tat-Cyclophilin A-Capsid Protein Enables Tat Encapsidation That Is Required for HIV-1 Infectivity. | A Tripartite Complex HIV-1 Tat-Cyclophilin A-Capsid Protein Enables Tat Encapsidation That Is Required for HIV-1 Infectivity.
Schatz M, Marty L, Ounadjela C, Tong PBV, Cardace I, Mettling C, Milhiet PE, Costa L, Godefroy C, Pugnière M, Guichou JF, Mesnard JM, Blaise M, Beaumelle B., Free PMC Article | 05/19/2023 |
| Accurate Prediction of Transcriptional Activity of Single Missense Variants in HIV Tat with Deep Learning. | Accurate Prediction of Transcriptional Activity of Single Missense Variants in HIV Tat with Deep Learning.
Derbel H, Giacoletto CJ, Benjamin R, Chen G, Schiller MR, Liu Q., Free PMC Article | 04/15/2023 |
| The lysine methyltransferase SMYD5 amplifies HIV-1 transcription and is post-transcriptionally upregulated by Tat and USP11. | The lysine methyltransferase SMYD5 amplifies HIV-1 transcription and is post-transcriptionally upregulated by Tat and USP11.
Boehm D, Lam V, Schnolzer M, Ott M., Free PMC Article | 04/4/2023 |
| Involvement of lncRNA TUG1 in HIV-1 Tat-Induced Astrocyte Senescence. | Involvement of lncRNA TUG1 in HIV-1 Tat-Induced Astrocyte Senescence.
Pillai PP, Kannan M, Sil S, Singh S, Thangaraj A, Chivero ET, Dagur RS, Tripathi A, Hu G, Periyasamy P, Buch S., Free PMC Article | 03/17/2023 |
| HIV-1 Tat drives the Fabp4/NF-kappaB feedback loop in microglia to mediate inflammatory response and neuronal apoptosis. | HIV-1 Tat drives the Fabp4/NF-κB feedback loop in microglia to mediate inflammatory response and neuronal apoptosis.
Zhou X, Zhou S, Tao J, Gao Y, Meng G, Cao D, Gao L. | 01/11/2023 |
| HIV-1 Tat Upregulates the Receptor for Advanced Glycation End Products and Superoxide Dismutase-2 in the Heart of Transgenic Mice. | HIV-1 Tat Upregulates the Receptor for Advanced Glycation End Products and Superoxide Dismutase-2 in the Heart of Transgenic Mice.
Qrareya AN, Wise NS, Hodges ER, Mahdi F, Stewart JA Jr, Paris JJ., Free PMC Article | 11/5/2022 |
| HIV-1 subtype C Tat exon-1 amino acid residue 24K is a signature for neurocognitive impairment. | HIV-1 subtype C Tat exon-1 amino acid residue 24K is a signature for neurocognitive impairment.
Ruhanya V, Jacobs GB, Paul RH, Joska JA, Seedat S, Nyandoro G, Glashoff RH, Engelbrecht S. | 09/24/2022 |
| An investigation of the HIV Tat C31S and R57S mutation on peripheral immune marker levels in South African participants: A pilot study. | An investigation of the HIV Tat C31S and R57S mutation on peripheral immune marker levels in South African participants: A pilot study.
Williams ME, Ruhanya V, Paul RH, Ipser JC, Stein DJ, Joska JA, Naudé PJW. | 07/30/2022 |
| Human immunodeficiency virus-1 Tat exerts its neurotoxic effects by downregulating Sonic hedgehog signaling. | Human immunodeficiency virus-1 Tat exerts its neurotoxic effects by downregulating Sonic hedgehog signaling.
Khan IA, Worrad AH, Singh MV, Maggirwar SB, Singh VB., Free PMC Article | 06/18/2022 |
| [Analysis of Tat protein characteristics in human immunodeficiency virus type 1 sub-subtype A6 (Retroviridae: Orthoretrovirinae: Lentivirus: Human immunodeficiency virus-1)]. | [Analysis of Tat protein characteristics in human immunodeficiency virus type 1 sub-subtype A6 (Retroviridae: Orthoretrovirinae: Lentivirus: Human immunodeficiency virus-1)].
Kuznetsova AI, Gromov KB, Kireev DE, Shlykova AV, Lopatukhin AE, Kazennova EV, Lebedev AV, Tumanov AS, Kim KV, Bobkova MR. | 05/7/2022 |
| HIV-1 Tat: An update on transcriptional and non-transcriptional functions. | HIV-1 Tat: An update on transcriptional and non-transcriptional functions.
Ali A, Mishra R, Kaur H, Chandra Banerjea A. | 02/12/2022 |
| Restoration of KCC2 Membrane Localization in Striatal Dopamine D2 Receptor-Expressing Medium Spiny Neurons Rescues Locomotor Deficits in HIV Tat-Transgenic Mice. | Restoration of KCC2 Membrane Localization in Striatal Dopamine D2 Receptor-Expressing Medium Spiny Neurons Rescues Locomotor Deficits in HIV Tat-Transgenic Mice.
Barbour AJ, Nass SR, Hahn YK, Hauser KF, Knapp PE., Free PMC Article | 01/22/2022 |
| UHRF1 Suppresses HIV-1 Transcription and Promotes HIV-1 Latency by Competing with p-TEFb for Ubiquitination-Proteasomal Degradation of Tat. | UHRF1 Suppresses HIV-1 Transcription and Promotes HIV-1 Latency by Competing with p-TEFb for Ubiquitination-Proteasomal Degradation of Tat.
Liang T, Zhang Q, Wu Z, Chen P, Huang Y, Liu S, Li L., Free PMC Article | 01/8/2022 |
| HIV-1C and HIV-1B Tat protein polymorphism in Southern Brazil. | HIV-1C and HIV-1B Tat protein polymorphism in Southern Brazil.
de Almeida SM, Rotta I, Vidal LRR, Dos Santos JS, Nath A, Johnson K, Letendre S, Ellis RJ, H. I. V. Neurobehavioral Research Center (HNRC) Group., Free PMC Article | 12/11/2021 |
| Mini review: Promotion of substance abuse in HIV patients: Biological mediation by HIV-1 Tat protein. | Mini review: Promotion of substance abuse in HIV patients: Biological mediation by HIV-1 Tat protein.
Cirino TJ, McLaughlin JP. | 11/27/2021 |
| The HIV-Tat protein interacts with Sp3 transcription factor and inhibits its binding to a distal site of the sod2 promoter in human pulmonary artery endothelial cells. | The HIV-Tat protein interacts with Sp3 transcription factor and inhibits its binding to a distal site of the sod2 promoter in human pulmonary artery endothelial cells.
Manes TL, Simenauer A, Geohring JL, Flemming J, Brehm M, Cota-Gomez A., Free PMC Article | 08/7/2021 |
| Rho-kinase inhibitor hydroxyfasudil protects against HIV-1 Tat-induced dysfunction of tight junction and neprilysin/Abeta transfer receptor expression in mouse brain microvessels. | Rho-kinase inhibitor hydroxyfasudil protects against HIV-1 Tat-induced dysfunction of tight junction and neprilysin/Aβ transfer receptor expression in mouse brain microvessels.
Chen Q, Wu Y, Yu Y, Wei J, Huang W., Free PMC Article | 07/31/2021 |
| HIV TAT-mediated microglial senescence: Role of SIRT3-dependent mitochondrial oxidative stress. | HIV TAT-mediated microglial senescence: Role of SIRT3-dependent mitochondrial oxidative stress.
Thangaraj A, Chivero ET, Tripathi A, Singh S, Niu F, Guo ML, Pillai P, Periyasamy P, Buch S., Free PMC Article | 06/26/2021 |
| Morphine and HIV-1 Tat interact to cause region-specific hyperphosphorylation of tau in transgenic mice. | Morphine and HIV-1 Tat interact to cause region-specific hyperphosphorylation of tau in transgenic mice.
Ohene-Nyako M, Nass SR, Hahn YK, Knapp PE, Hauser KF., Free PMC Article | 05/8/2021 |