| Deactivation of the Unfolded Protein Response Aggravated Renal AA Amyloidosis in HSF1 Deficiency Mice. | Deactivation of the Unfolded Protein Response Aggravated Renal AA Amyloidosis in HSF1 Deficiency Mice.
Liu W, Xia S, Yao F, Huo J, Qian J, Liu X, Bai L, Song Y, Qian J., | 05/31/2024 |
| Heat shock factor 1 drives regulatory T-cell induction to limit murine intestinal inflammation. | Heat shock factor 1 drives regulatory T-cell induction to limit murine intestinal inflammation.
Collins CB, Nguyen TT, Leddy RS, Alula KM, Yeckes AR, Strassheim D, Aherne CM, Luck ME, Karoor V, Jedlicka P, Pierce A, de Zoeten EF., Free PMC Article | 02/27/2024 |
| Disrupted HSF1 regulation in normal and exceptional brain aging. | Disrupted HSF1 regulation in normal and exceptional brain aging.
Trivedi R, Knopf B, Rakoczy S, Manocha GD, Brown-Borg H, Jurivich DA., Free PMC Article | 01/26/2024 |
| Pericentrin deficiency in smooth muscle cells augments atherosclerosis through HSF1-driven cholesterol biosynthesis and PERK activation. | Pericentrin deficiency in smooth muscle cells augments atherosclerosis through HSF1-driven cholesterol biosynthesis and PERK activation.
Majumder S, Chattopadhyay A, Wright JM, Guan P, Buja LM, Kwartler CS, Milewicz DM., Free PMC Article | 11/14/2023 |
| HSF1 enhances the attenuation of exosomes from mesenchymal stem cells to hemorrhagic shock induced lung injury by altering the protein profile of exosomes. | HSF1 enhances the attenuation of exosomes from mesenchymal stem cells to hemorrhagic shock induced lung injury by altering the protein profile of exosomes.
Jia D, Huan Z, Han J, Xu C, Sui L, Ge X. | 09/27/2023 |
| HSF1 inhibits microglia activation to attenuate neuroinflammation via regulating miR-214-3p and NFATc2 in Parkinson's disease. | HSF1 inhibits microglia activation to attenuate neuroinflammation via regulating miR-214-3p and NFATc2 in Parkinson's disease.
Liao Y, Gu Y, Wang J, Tian Y, Ni X, Zhou L, Ye Y, Xia G. | 05/3/2023 |
| Heat shock factor 1 induces a short burst of transcription of the clock gene Per2 during interbout arousal in mammalian hibernation. | Heat shock factor 1 induces a short burst of transcription of the clock gene Per2 during interbout arousal in mammalian hibernation.
Takamatsu N, Shirahata Y, Seki K, Nakamaru E, Ito M, Tsukamoto D., Free PMC Article | 05/1/2023 |
| HSF1 promotes CD69[+] Treg differentiation to inhibit colitis progression. | HSF1 promotes CD69(+) Treg differentiation to inhibit colitis progression.
Yu L, Zhou B, Zhu Y, Li L, Zhong Y, Zhu L, Wang H, Chen H, Xu J, Guo T, Feng L, Wang X, Cai Z, Wang J, Jin H., Free PMC Article | 04/19/2023 |
| Heat shock factor HSF1 regulates BDNF gene promoters upon acute stress in the hippocampus, together with pCREB. | Heat shock factor HSF1 regulates BDNF gene promoters upon acute stress in the hippocampus, together with pCREB.
Franks H, Wang R, Li M, Wang B, Wildmann A, Ortyl T, O'Brien S, Young D, Liao FF, Sakata K., Free PMC Article | 04/19/2023 |
| Tumor suppressor p53 regulates heat shock factor 1 protein degradation in Huntington's disease. | Tumor suppressor p53 regulates heat shock factor 1 protein degradation in Huntington's disease.
Mansky RH, Greguske EA, Yu D, Zarate N, Intihar TA, Tsai W, Brown TG, Thayer MN, Kumar K, Gomez-Pastor R., Free PMC Article | 04/4/2023 |
| HSF1 Attenuates the Release of Inflammatory Cytokines Induced by Lipopolysaccharide through Transcriptional Regulation of Atg10. | HSF1 Attenuates the Release of Inflammatory Cytokines Induced by Lipopolysaccharide through Transcriptional Regulation of Atg10.
Tan H, Huang F, Huang M, Wu X, Tong Z., Free PMC Article | 02/27/2023 |
| HSF1 Alleviates Brain Injury by Inhibiting NLRP3-Induced Pyroptosis in a Sepsis Model. | HSF1 Alleviates Brain Injury by Inhibiting NLRP3-Induced Pyroptosis in a Sepsis Model.
He YF, Hu XM, Khan MA, Yu BY, Sheng YC, Xiao XZ, Wan XX, Tan SP, Xiong K., Free PMC Article | 02/9/2023 |
| Inhibition of Heat Shock Factor 1 Signaling Decreases Hepatoblastoma Growth via Induction of Apoptosis. | Inhibition of Heat Shock Factor 1 Signaling Decreases Hepatoblastoma Growth via Induction of Apoptosis.
Hurley EH, Tao J, Liu S, Krutsenko Y, Singh S, Monga SP., Free PMC Article | 02/4/2023 |
| Skeletal muscle HSF1 prevents insulin resistance by improving glucose utilization. | Skeletal muscle HSF1 prevents insulin resistance by improving glucose utilization.
Li Y, Lin S, Xu X, Jin W, Su Y, Yuan F, Zhang Y, Li Z, Zhou Y, Zhu L, Zhang L. | 12/3/2022 |
| Hydrocortisone alleviates sepsis-induced acute kidney injury through HSF-1-mediated transcriptional suppression of XPO1. | Hydrocortisone alleviates sepsis-induced acute kidney injury through HSF-1-mediated transcriptional suppression of XPO1.
Jin L, Liao W, Zhou X, Wang Y, Qian J. | 11/26/2022 |
| Circadian disruption enhances HSF1 signaling and tumorigenesis in Kras-driven lung cancer. | Circadian disruption enhances HSF1 signaling and tumorigenesis in Kras-driven lung cancer.
Pariollaud M, Ibrahim LH, Irizarry E, Mello RM, Chan AB, Altman BJ, Shaw RJ, Bollong MJ, Wiseman RL, Lamia KA., Free PMC Article | 10/8/2022 |
| Loss of heat shock factor 1 promotes hepatic stellate cell activation and drives liver fibrosis. | Loss of heat shock factor 1 promotes hepatic stellate cell activation and drives liver fibrosis.
Choudhury A, Ratna A, Lim A, Sebastian RM, Moore CL, Filliol AA, Bledsoe J, Dai C, Schwabe RF, Shoulders MD, Mandrekar P., Free PMC Article | 10/8/2022 |
| Mitochondrial HSF1 triggers mitochondrial dysfunction and neurodegeneration in Huntington's disease. | Mitochondrial HSF1 triggers mitochondrial dysfunction and neurodegeneration in Huntington's disease.
Liu C, Fu Z, Wu S, Wang X, Zhang S, Chu C, Hong Y, Wu W, Chen S, Jiang Y, Wu Y, Song Y, Liu Y, Guo X., Free PMC Article | 07/16/2022 |
| HSF1 Alleviates Microthrombosis and Multiple Organ Dysfunction in Mice with Sepsis by Upregulating the Transcription of Tissue-Type Plasminogen Activator. | HSF1 Alleviates Microthrombosis and Multiple Organ Dysfunction in Mice with Sepsis by Upregulating the Transcription of Tissue-Type Plasminogen Activator.
Li T, Chen H, Shi X, Yin L, Tan C, Gu J, Liu Y, Li C, Xiao G, Liu K, Liu M, Tan S, Xiao Z, Zhang H, Xiao X. | 02/12/2022 |
| Heat Shock Factor 1 Directly Regulates Postsynaptic Scaffolding PSD-95 in Aging and Huntington's Disease and Influences Striatal Synaptic Density. | Heat Shock Factor 1 Directly Regulates Postsynaptic Scaffolding PSD-95 in Aging and Huntington's Disease and Influences Striatal Synaptic Density.
Zarate N, Intihar TA, Yu D, Sawyer J, Tsai W, Syed M, Carlson L, Gomez-Pastor R., Free PMC Article | 01/8/2022 |
| HSF1 promotes endometriosis development and glycolysis by up-regulating PFKFB3 expression. | HSF1 promotes endometriosis development and glycolysis by up-regulating PFKFB3 expression.
Wang Y, Xiu J, Yang T, Ren C, Yu Z., Free PMC Article | 01/1/2022 |
| Heat Shock Factor 1 Prevents Age-Related Hearing Loss by Decreasing Endoplasmic Reticulum Stress. | Heat Shock Factor 1 Prevents Age-Related Hearing Loss by Decreasing Endoplasmic Reticulum Stress.
Lee YY, Gil ES, Jeong IH, Kim H, Jang JH, Choung YH., Free PMC Article | 11/22/2021 |
| The heat shock response, determined by QuantiGene multiplex, is impaired in HD mouse models and not caused by HSF1 reduction. | The heat shock response, determined by QuantiGene multiplex, is impaired in HD mouse models and not caused by HSF1 reduction.
Gomez-Paredes C, Mason MA, Taxy BA, Papadopoulou AS, Paganetti P, Bates GP., Free PMC Article | 10/30/2021 |
| HSF1 functions as a key defender against palmitic acid-induced ferroptosis in cardiomyocytes. | HSF1 functions as a key defender against palmitic acid-induced ferroptosis in cardiomyocytes.
Wang N, Ma H, Li J, Meng C, Zou J, Wang H, Liu K, Liu M, Xiao X, Zhang H, Wang K. | 10/9/2021 |
| Jagged1-mediated myeloid Notch1 signaling activates HSF1/Snail and controls NLRP3 inflammasome activation in liver inflammatory injury. | Jagged1-mediated myeloid Notch1 signaling activates HSF1/Snail and controls NLRP3 inflammasome activation in liver inflammatory injury.
Jin Y, Li C, Xu D, Zhu J, Wei S, Zhong A, Sheng M, Duarte S, Coito AJ, Busuttil RW, Xia Q, Kupiec-Weglinski JW, Ke B., Free PMC Article | 10/9/2021 |