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    Hmox1 heme oxygenase 1 [ Mus musculus (house mouse) ]

    Gene ID: 15368, updated on 10-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Heme oxygenase-1 protects cells from replication stress.

    Heme oxygenase-1 protects cells from replication stress.
    Chudy P, Kochan J, Wawro M, Nguyen P, Gorczyca M, Varanko A, Retka A, Ghadei SS, Napieralska E, Grochot-Przęczek A, Szade K, Berendes LS, Park J, Sokołowski G, Yu Q, Józkowicz A, Nowak WN, Krzeptowski W., Free PMC Article

    10/2/2024
    The Role of Heme Oxygenase 1 in Rheumatoid Arthritis and IL-1 Induced Inflammatory Cell Model.

    The Role of Heme Oxygenase 1 in Rheumatoid Arthritis and IL-1 Induced Inflammatory Cell Model.
    Li M, Zheng N.

    09/25/2024
    Inhibition of HMOX1 by MAFG potentiates the development of depression-like behavior in mice associated with astrocyte-mediated neuroinflammation.

    Inhibition of HMOX1 by MAFG potentiates the development of depression‑like behavior in mice associated with astrocyte-mediated neuroinflammation.
    Ye Y, Liang J, Xu C, Liu Y, Chen J, Zhu Y.

    08/30/2024
    The Bach1/HO-1 pathway regulates oxidative stress and contributes to ferroptosis in doxorubicin-induced cardiomyopathy in H9c2 cells and mice.

    The Bach1/HO-1 pathway regulates oxidative stress and contributes to ferroptosis in doxorubicin-induced cardiomyopathy in H9c2 cells and mice.
    Wang Y, Qiu J, Yan H, Zhang N, Gao S, Xu N, Wang C, Lou H.

    08/27/2024
    Targeted expression of heme oxygenase-1 in satellite cells improves skeletal muscle pathology in dystrophic mice.

    Targeted expression of heme oxygenase-1 in satellite cells improves skeletal muscle pathology in dystrophic mice.
    Florczyk-Soluch U, Polak K, Jelinkova S, Bronisz-Budzyńska I, Sabo R, Bolisetty S, Agarwal A, Werner E, Józkowicz A, Stępniewski J, Szade K, Dulak J., Free PMC Article

    06/26/2024
    HO-1 upregulation promotes mitophagy-dependent ferroptosis in PM2.5-exposed hippocampal neurons.

    HO-1 upregulation promotes mitophagy-dependent ferroptosis in PM2.5-exposed hippocampal neurons.
    Li X, Ran Q, He X, Peng D, Xiong A, Jiang M, Zhang L, Wang J, Bai L, Liu S, Li S, Sun B, Li G.

    05/29/2024
    [Heme oxygenase-1 (HO-1) gene knockout affects the balance of lung immune cell composition and aggravates inflammatory injury in lung tissues of LPS-induced acute lung injury (ALI) mice].

    [Heme oxygenase-1 (HO-1) gene knockout affects the balance of lung immune cell composition and aggravates inflammatory injury in lung tissues of LPS-induced acute lung injury (ALI) mice].
    Yang J, Shi J, Guan X, Ge L, Yu J.

    05/24/2024
    Mechanism of Fat Mass and Obesity-Related Gene-Mediated Heme Oxygenase-1 m6A Modification in the Recovery of Neurological Function in Mice with Spinal Cord Injury.

    Mechanism of Fat Mass and Obesity-Related Gene-Mediated Heme Oxygenase-1 m6A Modification in the Recovery of Neurological Function in Mice with Spinal Cord Injury.
    Xu J, Ren Z, Niu T, Li S., Free PMC Article

    05/6/2024
    Regional variations in allergen-induced airway inflammation correspond to changes in soluble guanylyl cyclase heme and expression of heme oxygenase-1.

    Regional variations in allergen-induced airway inflammation correspond to changes in soluble guanylyl cyclase heme and expression of heme oxygenase-1.
    Sumi MP, Westcott R, Stuehr E, Ghosh C, Stuehr DJ, Ghosh A.,

    03/25/2024
    Melatonin MT1 receptors regulate the Sirt1/Nrf2/Ho-1/Gpx4 pathway to prevent alpha-synuclein-induced ferroptosis in Parkinson's disease.

    Melatonin MT1 receptors regulate the Sirt1/Nrf2/Ho-1/Gpx4 pathway to prevent α-synuclein-induced ferroptosis in Parkinson's disease.
    Lv QK, Tao KX, Yao XY, Pang MZ, Cao BE, Liu CF, Wang F.

    03/19/2024
    Heme oxygenase-1 alleviates allergic airway inflammation by suppressing NF-kappaB-mediated pyroptosis of bronchial epithelial cells.

    Heme oxygenase-1 alleviates allergic airway inflammation by suppressing NF-κB-mediated pyroptosis of bronchial epithelial cells.
    Lv J, Zhou Y, Wang J, Wu Y, Yu Q, Zhang M, Su W, Tang Z, Wu Q, Wu M, Xia Z.

    02/13/2024
    Microglial FoxO3a deficiency ameliorates ferroptosis-induced brain injury of intracerebral haemorrhage via regulating autophagy and heme oxygenase-1.

    Microglial FoxO3a deficiency ameliorates ferroptosis-induced brain injury of intracerebral haemorrhage via regulating autophagy and heme oxygenase-1.
    Wang R, Liang Z, Xue X, Mei H, Ji L, Wang B, Chen W, Gao C, Yuan S, Wu T, Qi H, Hu S, Yi L, Song Y, Liao R, Chen B., Free PMC Article

    01/30/2024
    Inhibition of heme oxygenase 1 alleviates thoracic aortic aneurysm via restoration of extracellular matrix.

    Inhibition of heme oxygenase 1 alleviates thoracic aortic aneurysm via restoration of extracellular matrix.
    Song W, Shen K, Fu G, Qin L, Bagaber G, Chen J, Wei L.

    01/28/2024
    HO-1-Mediated Autophagic Restoration Protects Lens Epithelial Cells Against Oxidative Stress and Cellular Senescence.

    HO-1-Mediated Autophagic Restoration Protects Lens Epithelial Cells Against Oxidative Stress and Cellular Senescence.
    Wang L, Lou W, Zhang Y, Chen Z, Huang Y, Jin H., Free PMC Article

    12/15/2023
    Adoptive transfer of immature dendritic cells with high HO-1 expression delays the onset of T1DM in NOD mice.

    Adoptive transfer of immature dendritic cells with high HO-1 expression delays the onset of T1DM in NOD mice.
    Yang X, Ma Z, Tan X, Shi Y, Yuan M, Chen G, Luo X, Hou L.

    12/6/2023
    Expression of angiogenic factors in the placenta of heme oxygenase-1 deficient mouse embryo.

    Expression of angiogenic factors in the placenta of heme oxygenase-1 deficient mouse embryo.
    Rana M, Choubey P, Nandi G, Jain S, Bajaj D, Sharma S, Basu-Modak S.

    12/4/2023
    Pregnane X receptor (PXR) deficiency protects against spinal cord injury by activating NRF2/HO-1 pathway.

    Pregnane X receptor (PXR) deficiency protects against spinal cord injury by activating NRF2/HO-1 pathway.
    Xuan LN, Hu ZX, Jiang ZF, Zhang C, Sun XW, Ming WH, Liu HT, Qiao RF, Shen LJ, Liu SB, Wang GY, Wen L, Luan ZL, Yin J., Free PMC Article

    11/28/2023
    Heme oxygenase-1 increases intracellular iron storage and suppresses inflammatory response of macrophages by inhibiting M1 polarization.

    Heme oxygenase-1 increases intracellular iron storage and suppresses inflammatory response of macrophages by inhibiting M1 polarization.
    Tang X, Li Y, Zhao J, Liang L, Zhang K, Zhang X, Yu H, Du H.

    11/7/2023
    Altered Expression of Heme Oxygenase 2 in Heme Oxygenase 1-deficient Mouse Embryos.

    Altered Expression of Heme Oxygenase 2 in Heme Oxygenase 1-deficient Mouse Embryos.
    Rana M, Bajaj D, Choubey P, Jain S, Basu-Modak S., Free PMC Article

    10/20/2023
    Phloroglucinol possesses anti-inflammatory activities by regulating AMPK/Nrf2/HO-1 signaling pathway in LPS-stimulated RAW264.7 murine macrophages.

    Phloroglucinol possesses anti-inflammatory activities by regulating AMPK/Nrf2/HO-1 signaling pathway in LPS-stimulated RAW264.7 murine macrophages.
    Marasinghe CK, Jung WK, Je JY.

    09/22/2023
    p-Nrf2/HO-1 Pathway Involved in Methamphetamine-induced Executive Dysfunction through Endoplasmic Reticulum Stress and Apoptosis in the Dorsal Striatum.

    p-Nrf2/HO-1 Pathway Involved in Methamphetamine-induced Executive Dysfunction through Endoplasmic Reticulum Stress and Apoptosis in the Dorsal Striatum.
    Wei T, Li JD, Wang YJ, Zhao W, Duan F, Wang Y, Xia LL, Jiang ZB, Song X, Zhu YQ, Shao WY, Wang Z, Bi KS, Li H, Zhang XC, Jiao DL.

    09/15/2023
    Remote ischemic conditioning attenuates oxidative stress and inflammation via the Nrf2/HO-1 pathway in MCAO mice.

    Remote ischemic conditioning attenuates oxidative stress and inflammation via the Nrf2/HO-1 pathway in MCAO mice.
    Sun YY, Zhu HJ, Zhao RY, Zhou SY, Wang MQ, Yang Y, Guo ZN., Free PMC Article

    09/13/2023
    ETS1 Ameliorates Hyperoxia-Induced Bronchopulmonary Dysplasia in Mice by Activating Nrf2/HO-1 Mediated Ferroptosis.

    ETS1 Ameliorates Hyperoxia-Induced Bronchopulmonary Dysplasia in Mice by Activating Nrf2/HO-1 Mediated Ferroptosis.
    Yang M, Chen Y, Huang X, Shen F, Meng Y., Free PMC Article

    08/30/2023
    HMOX1 silencing prevents doxorubicin-induced cardiomyocyte injury, mitochondrial dysfunction, and ferroptosis by downregulating CTGF.

    HMOX1 silencing prevents doxorubicin-induced cardiomyocyte injury, mitochondrial dysfunction, and ferroptosis by downregulating CTGF.
    Qian J, Wan W, Fan M.

    08/11/2023
    Heme oxygenase 1 alleviates nonalcoholic steatohepatitis by suppressing hepatic ferroptosis.

    Heme oxygenase 1 alleviates nonalcoholic steatohepatitis by suppressing hepatic ferroptosis.
    Yuan X, Li L, Zhang Y, Ai R, Li D, Dou Y, Hou M, Zhao D, Zhao S, Nan Y., Free PMC Article

    07/12/2023
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