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    CYBB cytochrome b-245 beta chain [ Homo sapiens (human) ]

    Gene ID: 1536, updated on 14-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Modulation of NOX2 causes obesity-mediated atrial fibrillation.

    Modulation of NOX2 causes obesity-mediated atrial fibrillation.
    Sridhar A, DeSantiago J, Chen H, Pavel MA, Ly O, Owais A, Barney M, Jousma J, Nukala SB, Abdelhady K, Massad M, Rizkallah LE, Ong SG, Rehman J, Darbar D., Free PMC Article

    11/12/2024
    The Association between NADPH Oxidase 2 (NOX2) and Drug Resistance in Cancer.

    The Association between NADPH Oxidase 2 (NOX2) and Drug Resistance in Cancer.
    Dong S, Chen C, Di C, Wang S, Dong Q, Lin W, Liu D.

    10/1/2024
    Structural basis for EROS binding to human phagocyte NADPH oxidase NOX2.

    Structural basis for EROS binding to human phagocyte NADPH oxidase NOX2.
    Liang S, Liu A, Liu Y, Wang F, Zhou Y, Long Y, Wang T, Liu Z, Ren R, Ye RD.,

    06/5/2024
    CYBB-Mediated Ferroptosis Associated with Immunosuppression in Mycobacterium leprae-Infected Monocyte-Derived Macrophages.

    CYBB-Mediated Ferroptosis Associated with Immunosuppression in Mycobacterium leprae-Infected Monocyte-Derived Macrophages.
    Wang Z, Liu T, Wang Z, Mi Z, Zhang Y, Wang C, Sun L, Ma S, Xue X, Liu H, Zhang F.

    03/27/2024
    Nox2 inhibition reduces trophoblast ferroptosis in preeclampsia via the STAT3/GPX4 pathway.

    Nox2 inhibition reduces trophoblast ferroptosis in preeclampsia via the STAT3/GPX4 pathway.
    Xu X, Zhu M, Zu Y, Wang G, Li X, Yan J.

    03/20/2024
    Structure of human phagocyte NADPH oxidase in the activated state.

    Structure of human phagocyte NADPH oxidase in the activated state.
    Liu X, Shi Y, Liu R, Song K, Chen L.

    03/18/2024
    Association Between Serum Levels of Nicotinamide-Adenine Dinucleotide Phosphate Oxidase 2 and the Development of Atrial Fibrillation After Isolated Coronary Artery Bypass Grafting: A Prospective Pilot Study.

    Association Between Serum Levels of Nicotinamide-Adenine Dinucleotide Phosphate Oxidase 2 and the Development of Atrial Fibrillation After Isolated Coronary Artery Bypass Grafting: A Prospective Pilot Study.
    Yan H, Zhang J, Wu FQ, Du GF.

    12/5/2023
    Activated SIRT1 contributes to DPT-induced glioma cell parthanatos by upregulation of NOX2 and NAT10.

    Activated SIRT1 contributes to DPT-induced glioma cell parthanatos by upregulation of NOX2 and NAT10.
    Liang SP, Wang XZ, Piao MH, Chen X, Wang ZC, Li C, Wang YB, Lu S, He C, Wang YL, Chi GF, Ge PF., Free PMC Article

    10/12/2023
    Ang II Promotes ET-1 Production by Regulating NOX2 Activity Through Transcription Factor Oct-1.

    Ang II Promotes ET-1 Production by Regulating NOX2 Activity Through Transcription Factor Oct-1.
    Kamhieh-Milz J, Chen L, Goettsch C, Pfefferkorn AM, Hofmann A, Brunssen C, Müller GM, Walther T, Ashraf MI, Moll G, Morawietz H, Witowski J, Catar R.

    09/6/2023
    Novel mutations in CYBB Gene Cause X-linked chronic Granulomatous Disease in Pakistani patients.

    Novel mutations in CYBB Gene Cause X-linked chronic Granulomatous Disease in Pakistani patients.
    Gul I, Khan TA, Akbar NU, Gul N, Ali R, Khan SN., Free PMC Article

    08/4/2023
    The Expression and Role of NADPH Oxidase 2 in Colon Cancer.

    The Expression and Role of NADPH Oxidase 2 in Colon Cancer.
    Takiguchi K, Shimizu H, Shoda K, Shiraishi K, Furuya S, Hosomura N, Akaike H, Kawaguchi Y, Amemiya H, Kawaida H, Mochizuki K, Kondo T, Ichikawa D.

    06/2/2023
    NADPH Oxidase Subunit CYBB Confers Chemotherapy and Ferroptosis Resistance in Mesenchymal Glioblastoma via Nrf2/SOD2 Modulation.

    NADPH Oxidase Subunit CYBB Confers Chemotherapy and Ferroptosis Resistance in Mesenchymal Glioblastoma via Nrf2/SOD2 Modulation.
    Su IC, Su YK, Setiawan SA, Yadav VK, Fong IH, Yeh CT, Lin CM, Liu HW., Free PMC Article

    05/19/2023
    De Novo Somatic Mosaicism of CYBB Caused by Intronic LINE-1 Element Insertion Resulting in Chronic Granulomatous Disease.

    De Novo Somatic Mosaicism of CYBB Caused by Intronic LINE-1 Element Insertion Resulting in Chronic Granulomatous Disease.
    Yu L, Li W, Lv G, Sun G, Yang L, Chen J, Zhou L, Ding Y, Zhang Z, Tang X, An Y, Zhao X.

    01/21/2023
    NOX2 and NOX5 are increased in cardiac microvascular endothelium of deceased COVID-19 patients.

    NOX2 and NOX5 are increased in cardiac microvascular endothelium of deceased COVID-19 patients.
    Jiang Z, Wu L, van der Leeden B, van Rossum AC, Niessen HWM, Krijnen PAJ., Free PMC Article

    01/11/2023
    NADPH Oxidase 2 Has a Crucial Role in Cell Cycle Progression of Esophageal Squamous Cell Carcinoma.

    NADPH Oxidase 2 Has a Crucial Role in Cell Cycle Progression of Esophageal Squamous Cell Carcinoma.
    Shimizu H, Katsurahara K, Inoue H, Shiozaki A, Kosuga T, Kudou M, Arita T, Konishi H, Komatsu S, Fujiwara H, Morinaga Y, Konishi E, Otsuji E.

    11/19/2022
    The NADPH oxidase NOX2 is a marker of adverse prognosis involved in chemoresistance of acute myeloid leukemias.

    The NADPH oxidase NOX2 is a marker of adverse prognosis involved in chemoresistance of acute myeloid leukemias.
    Paolillo R, Boulanger M, Gâtel P, Gabellier L, De Toledo M, Tempé D, Hallal R, Akl D, Moreaux J, Baik H, Gueret E, Recher C, Sarry JE, Cartron G, Piechaczyk M, Bossis G., Free PMC Article

    11/5/2022
    Structure of the core human NADPH oxidase NOX2.

    Structure of the core human NADPH oxidase NOX2.
    Noreng S, Ota N, Sun Y, Ho H, Johnson M, Arthur CP, Schneider K, Lehoux I, Davies CW, Mortara K, Wong K, Seshasayee D, Masureel M, Payandeh J, Yi T, Koerber JT., Free PMC Article

    10/22/2022
    Low-grade endotoxemia and NOX2 in patients with coronary microvascular angina.

    Low-grade endotoxemia and NOX2 in patients with coronary microvascular angina.
    Loffredo L, Ivanov V, Ciobanu N, Ivanov M, Ciacci P, Nocella C, Cammisotto V, Orlando F, Paraninfi A, Maggio E, D'Amico A, Rosa P, Popovici M, Bartimoccia S, Barillà F, Deseatnicova E, Gutu E, Violi F, Carnevale R.

    10/15/2022
    Construction of three-gene-based prognostic signature and analysis of immune cells infiltration in children and young adults with B-acute lymphoblastic leukemia.

    Construction of three-gene-based prognostic signature and analysis of immune cells infiltration in children and young adults with B-acute lymphoblastic leukemia.
    Xiang C, Wu J, Yu L., Free PMC Article

    07/23/2022
    Therapeutic hypothermia augments the restorative effects of PKC-beta and Nox2 inhibition on an in vitro model of human blood-brain barrier.

    Therapeutic hypothermia augments the restorative effects of PKC-β and Nox2 inhibition on an in vitro model of human blood-brain barrier.
    Kadir RRA, Alwjwaj M, McCarthy Z, Bayraktutan U., Free PMC Article

    04/16/2022
    Inducibility, but not stability, of atrial fibrillation is increased by NOX2 overexpression in mice.

    Inducibility, but not stability, of atrial fibrillation is increased by NOX2 overexpression in mice.
    Mighiu AS, Recalde A, Ziberna K, Carnicer R, Tomek J, Bub G, Brewer AC, Verheule S, Shah AM, Simon JN, Casadei B., Free PMC Article

    03/5/2022
    Chronic Granulomatous Disease and Myelodysplastic Syndrome in a Patient with a Novel Mutation in CYBB.

    Chronic Granulomatous Disease and Myelodysplastic Syndrome in a Patient with a Novel Mutation in CYBB.
    Reis BCS, Cunha DP, Bueno APS, Carvalho FAA, Dutra J, Mello FV, Ribeiro MCM, Milito CB, da Costa ES, Vasconcelos Z., Free PMC Article

    02/12/2022
    Anakinra for Treatment of Liver Abscesses in a Patient with a Novel CYBB Variant of Chronic Granulomatous Disease.

    Anakinra for Treatment of Liver Abscesses in a Patient with a Novel CYBB Variant of Chronic Granulomatous Disease.
    To C, Williams A, Droney L.

    02/5/2022
    A Novel CYBB Variant Causing X-Linked Chronic Granulomatous Disease in a Patient with Empyema.

    A Novel CYBB Variant Causing X-Linked Chronic Granulomatous Disease in a Patient with Empyema.
    Kitcharoensakkul M, Song Z, Bednarski JJ, Dinauer M.

    01/15/2022
    Expanding the Clinical Phenotype of Chronic Granulomatous Disease: a Female Patient with a De Novo Mutation in CYBB.

    Expanding the Clinical Phenotype of Chronic Granulomatous Disease: a Female Patient with a De Novo Mutation in CYBB.
    Wu EY, Kuehn HS, Rosenzweig SD, Aksentijevich I, McShane DB., Free PMC Article

    01/15/2022
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