| Foxg1 regulates translation of neocortical neuronal genes, including the main NMDA receptor subunit gene, Grin1. | Foxg1 regulates translation of neocortical neuronal genes, including the main NMDA receptor subunit gene, Grin1.
Artimagnella O, Maftei ES, Esposito M, Sanges R, Mallamaci A., Free PMC Article | 08/31/2024 |
| Menin Deficiency Induces Autism-Like Behaviors by Regulating Foxg1 Transcription and Participates in Foxg1-Related Encephalopathy. | Menin Deficiency Induces Autism-Like Behaviors by Regulating Foxg1 Transcription and Participates in Foxg1-Related Encephalopathy.
Zhuang K, Leng L, Su X, Wang S, Su Y, Chen Y, Yuan Z, Zi L, Li J, Xie W, Yan S, Xia Y, Wang H, Li H, Chen Z, Yuan T, Zhang J., Free PMC Article | 07/4/2024 |
| Foxg1 bimodally tunes L1-mRNA and -DNA dynamics in the developing murine neocortex. | Foxg1 bimodally tunes L1-mRNA and -DNA dynamics in the developing murine neocortex.
Liuzzi G, Artimagnella O, Frisari S, Mallamaci A., Free PMC Article | 05/31/2024 |
| Conditional Deletion of Foxg1 Delayed Myelination during Early Postnatal Brain Development. | Conditional Deletion of Foxg1 Delayed Myelination during Early Postnatal Brain Development.
Cao G, Sun C, Shen H, Qu D, Shen C, Lu H., Free PMC Article | 09/30/2023 |
| FOXG1 is involved in mouse ovarian functions and embryogenesis. | FOXG1 is involved in mouse ovarian functions and embryogenesis.
Yan X, Hou L, Zhang C. | 09/13/2023 |
| FOXG1 drives transcriptomic networks to specify principal neuron subtypes during the development of the medial pallium. | FOXG1 drives transcriptomic networks to specify principal neuron subtypes during the development of the medial pallium.
Ba R, Yang L, Zhang B, Jiang P, Ding Z, Zhou X, Yang Z, Zhao C., Free PMC Article | 02/18/2023 |
| Differential vulnerability of adult neurogenic niches to dosage of the neurodevelopmental-disorder linked gene Foxg1. | Differential vulnerability of adult neurogenic niches to dosage of the neurodevelopmental-disorder linked gene Foxg1.
Schäffner I, Wittmann MT, Vogel T, Lie DC., Free PMC Article | 01/14/2023 |
| FOXG1 Contributes Adult Hippocampal Neurogenesis in Mice. | FOXG1 Contributes Adult Hippocampal Neurogenesis in Mice.
Wang J, Zhai HR, Ma SF, Shi HZ, Zhang WJ, Yun Q, Liu WJ, Liu ZZ, Zhang WN., Free PMC Article | 12/31/2022 |
| Behavioral and brain anatomical analysis of Foxg1 heterozygous mice. | Behavioral and brain anatomical analysis of Foxg1 heterozygous mice.
Erickson KR, Farmer R, Merritt JK, Miletic Lanaghan Z, Does MD, Ramadass K, Landman BA, Cutting LE, Neul JL., Free PMC Article | 10/22/2022 |
| FOXG1 as a Potential Therapeutic Target for Alzheimer's Disease with a Particular Focus on Cell Cycle Regulation. | FOXG1 as a Potential Therapeutic Target for Alzheimer's Disease with a Particular Focus on Cell Cycle Regulation.
Wang J, Ma SF, Yun Q, Liu WJ, Zhai HR, Shi HZ, Xie LG, Qian JJ, Zhao CJ, Zhang WN. | 04/23/2022 |
| Foxg1 Upregulation Enhances Neocortical Activity. | Foxg1 Upregulation Enhances Neocortical Activity.
Tigani W, Rossi MP, Artimagnella O, Santo M, Rauti R, Sorbo T, Ulloa Severino FP, Provenzano G, Allegra M, Caleo M, Ballerini L, Bozzi Y, Mallamaci A. | 12/4/2021 |
| FoxG1 regulates the formation of cortical GABAergic circuit during an early postnatal critical period resulting in autism spectrum disorder-like phenotypes. | FoxG1 regulates the formation of cortical GABAergic circuit during an early postnatal critical period resulting in autism spectrum disorder-like phenotypes.
Miyoshi G, Ueta Y, Natsubori A, Hiraga K, Osaki H, Yagasaki Y, Kishi Y, Yanagawa Y, Fishell G, Machold RP, Miyata M., Free PMC Article | 07/10/2021 |
| Knockdown of Foxg1 in Sox9+ supporting cells increases the trans-differentiation of supporting cells into hair cells in the neonatal mouse utricle. | Knockdown of Foxg1 in Sox9+ supporting cells increases the trans-differentiation of supporting cells into hair cells in the neonatal mouse utricle.
Zhang Y, Zhang S, Zhang Z, Dong Y, Ma X, Qiang R, Chen Y, Gao X, Zhao C, Chen F, He S, Chai R., Free PMC Article | 04/24/2021 |
| Foxg1 Directly Represses Dbx1 to Confine the POA and Subsequently Regulate Ventral Telencephalic Patterning. | Foxg1 Directly Represses Dbx1 to Confine the POA and Subsequently Regulate Ventral Telencephalic Patterning.
Du A, Wu X, Chen H, Bai QR, Han X, Liu B, Zhang X, Ding Z, Shen Q, Zhao C. | 11/21/2020 |
| Foxg1 Antagonizes Neocortical Stem Cell Progression to Astrogenesis. | Foxg1 Antagonizes Neocortical Stem Cell Progression to Astrogenesis.
Falcone C, Santo M, Liuzzi G, Cannizzaro N, Grudina C, Valencic E, Peruzzotti-Jametti L, Pluchino S, Mallamaci A. | 11/21/2020 |
| The nuclear transcription factor FoxG1 affects the sensitivity of mimetic aging hair cells to inflammation by regulating autophagy pathways. | The nuclear transcription factor FoxG1 affects the sensitivity of mimetic aging hair cells to inflammation by regulating autophagy pathways.
He ZH, Zou SY, Li M, Liao FL, Wu X, Sun HY, Zhao XY, Hu YJ, Li D, Xu XX, Chen S, Sun Y, Chai RJ, Kong WJ., Free PMC Article | 10/3/2020 |
| Foxg1-deficient SST-interneurons exhibited decreased membrane excitability and a changed ratio of electrophysiological firing patterns, which subsequently led to an excitatory/inhibitory imbalance. Moreover, cognitive defects, limited social interactions, and depression-like behaviors were detected in Foxg1 cKO mice. | Loss of Foxg1 Impairs the Development of Cortical SST-Interneurons Leading to Abnormal Emotional and Social Behaviors.
Chen D, Wang C, Li M, She X, Yuan Y, Chen H, Zhang W, Zhao C. | 07/18/2020 |
| Foxg1 plays an important role in maintaining the neural plasticity, which is vital to high-grade function. | Disruption of Foxg1 impairs neural plasticity leading to social and cognitive behavioral defects.
Yu B, Liu J, Su M, Wang C, Chen H, Zhao C., Free PMC Article | 06/6/2020 |
| Study shows that postnatally deleted Foxg1 in interneurons, there is a decreased migration capacity in cortical interneurons and abnormal distributions of interneurons subtypes. | Foxg1 Regulates the Postnatal Development of Cortical Interneurons.
Shen W, Ba R, Su Y, Ni Y, Chen D, Xie W, Pleasure SJ, Zhao C., Free PMC Article | 05/23/2020 |
| Study shows that Foxg1 Overexpression in Neocortical Pyramids Stimulates Dendrite Elongation Via Hes1 and pCreb1 Upregulation. | Foxg1 Overexpression in Neocortical Pyramids Stimulates Dendrite Elongation Via Hes1 and pCreb1 Upregulation.
Chiola S, Do MD, Centrone L, Mallamaci A. | 05/16/2020 |
| this study provides new evidence for the role of Foxg1 in regulating hair cell regeneration from supporting cell and progenitors in the neonatal mouse cochlea. | Knockdown of Foxg1 in supporting cells increases the trans-differentiation of supporting cells into hair cells in the neonatal mouse cochlea.
Zhang S, Zhang Y, Dong Y, Guo L, Zhang Z, Shao B, Qi J, Zhou H, Zhu W, Yan X, Hong G, Zhang L, Zhang X, Tang M, Zhao C, Gao X, Chai R., Free PMC Article | 04/11/2020 |
| FOXG1 regulates PRKAR2B expression in the hippocampus both on transcriptional and post-transcriptional levels. | FOXG1 Regulates PRKAR2B Transcriptionally and Posttranscriptionally via miR200 in the Adult Hippocampus.
Weise SC, Arumugam G, Villarreal A, Videm P, Heidrich S, Nebel N, Dumit VI, Sananbenesi F, Reimann V, Craske M, Schilling O, Hess WR, Fischer A, Backofen R, Vogel T., Free PMC Article | 01/18/2020 |
| Ecrg4 has a role in aging of neural stem cells in a Foxg1-dependent manner | Ecrg4 deficiency extends the replicative capacity of neural stem cells in a Foxg1-dependent manner.
Nakatani Y, Kiyonari H, Kondo T. | 01/4/2020 |
| Study demonstrates that Foxg1 action in post-mitotic neurons is imperative to generate the cortical laminar structure in an inside-out fashion and to form the corpus callosum. | FOXG1 Orchestrates Neocortical Organization and Cortico-Cortical Connections.
Cargnin F, Kwon JS, Katzman S, Chen B, Lee JW, Lee SK., Free PMC Article | 08/24/2019 |
| Results indicate that knockout of Foxg1 induces an extra row of hair cells (HCs) via Notch signaling inhibition and induces subsequent apoptosis of these HCs by inhibiting the Wnt, IGF, and EGF signaling pathways. This study thus provides new evidence for the function and mechanism of FOXG1 in HC development and survival in mice. | The role of FOXG1 in the postnatal development and survival of mouse cochlear hair cells.
He Z, Fang Q, Li H, Shao B, Zhang Y, Zhang Y, Han X, Guo R, Cheng C, Guo L, Shi L, Li A, Yu C, Kong W, Zhao C, Gao X, Chai R. | 03/9/2019 |