| [Epidermal factor Foxn1 as a regulator of antioxidant defense in the skin]. | [Epidermal factor Foxn1 as a regulator of antioxidant defense in the skin].
Machcińska-Zielińska S, Gawrońska-Kozak B. | 08/14/2024 |
| Administration of recombinant FOXN1 protein attenuates Alzheimer's pathology in mice. | Administration of recombinant FOXN1 protein attenuates Alzheimer's pathology in mice.
Zhao J, Zhang Z, Lai KC, Lai L., Free PMC Article | 09/29/2023 |
| Dermal white adipose tissue development and metabolism: The role of transcription factor Foxn1. | Dermal white adipose tissue development and metabolism: The role of transcription factor Foxn1.
Walendzik K, Kopcewicz M, Wiśniewska J, Opyd P, Machcińska-Zielińska S, Gawrońska-Kozak B. | 09/22/2023 |
| Foxn1 overexpression promotes thymic epithelial progenitor cell proliferation and mTEC maintenance, but does not prevent thymic involution. | Foxn1 overexpression promotes thymic epithelial progenitor cell proliferation and mTEC maintenance, but does not prevent thymic involution.
Li J, Wachsmuth LP, Xiao S, Condie BG, Manley NR., Free PMC Article | 04/26/2023 |
| Limits to in vivo fate changes of epithelia in thymus and parathyroid by ectopic expression of transcription factors Gcm2 and Foxn1. | Limits to in vivo fate changes of epithelia in thymus and parathyroid by ectopic expression of transcription factors Gcm2 and Foxn1.
Nagakubo D, Hirakawa M, Iwanami N, Boehm T., Free PMC Article | 08/20/2022 |
| Protection against autoimmunity is driven by thymic epithelial cell-mediated regulation of Treg development. | Protection against autoimmunity is driven by thymic epithelial cell-mediated regulation of T(reg) development.
Haftmann C, Zwicky P, Ingelfinger F, Mair F, Floess S, Riedel R, Durek P, Spalinger MR, Friebel E, Leung BP, Lutz M, Puertas N, Amorim A, Schärli S, Becher B, Kisielow J, Waisman A, Mashreghi MF, Huehn J, Becher B. | 03/12/2022 |
| Delayed maturation of thymic epithelium in mice with specific deletion of beta-catenin gene in FoxN1 positive cells. | Delayed maturation of thymic epithelium in mice with specific deletion of β-catenin gene in FoxN1 positive cells.
Montero-Herradón S, Zapata AG., Free PMC Article | 03/12/2022 |
| P63 targeted deletion under the FOXN1 promoter disrupts pre-and post-natal thymus development, function and maintenance as well as induces severe hair loss. | P63 targeted deletion under the FOXN1 promoter disrupts pre-and post-natal thymus development, function and maintenance as well as induces severe hair loss.
Stefanski HE, Xing Y, Nicholls J, Jonart L, Goren E, Taylor PA, Mills AA, Riddle M, McGrath J, Tolar J, Hollander GA, Blazar BR., Free PMC Article | 02/19/2022 |
| Dermal White Adipose Tissue (dWAT) Is Regulated by Foxn1 and Hif-1alpha during the Early Phase of Skin Wound Healing. | Dermal White Adipose Tissue (dWAT) Is Regulated by Foxn1 and Hif-1α during the Early Phase of Skin Wound Healing.
Gawronska-Kozak B, Walendzik K, Machcinska S, Padzik A, Kopcewicz M, Wiśniewska J., Free PMC Article | 02/5/2022 |
| High-Oxygen Submersion Fetal Thymus Organ Cultures Enable FOXN1-Dependent and -Independent Support of T Lymphopoiesis. | High-Oxygen Submersion Fetal Thymus Organ Cultures Enable FOXN1-Dependent and -Independent Support of T Lymphopoiesis.
Han J, Zúñiga-Pflücker JC., Free PMC Article | 10/2/2021 |
| Impairment of the Hif-1alpha regulatory pathway in Foxn1-deficient (Foxn1(-/-) ) mice affects the skin wound healing process. | Impairment of the Hif-1α regulatory pathway in Foxn1-deficient (Foxn1(-/-) ) mice affects the skin wound healing process.
Machcinska S, Kopcewicz M, Bukowska J, Walendzik K, Gawronska-Kozak B. | 06/26/2021 |
| Foxn1 and Prkdc genes are important for testis function: evidence from nude and scid adult mice. | Foxn1 and Prkdc genes are important for testis function: evidence from nude and scid adult mice.
Oliveira CF, Lara NL, Lacerda SM, Resende RR, França LR, Avelar GF. | 02/2/2021 |
| The Transcription Factor FOXN1 Regulates Skin Adipogenesis and Affects Susceptibility to Diet-Induced Obesity. | The Transcription Factor FOXN1 Regulates Skin Adipogenesis and Affects Susceptibility to Diet-Induced Obesity.
Walendzik K, Kopcewicz M, Bukowska J, Panasiewicz G, Szafranska B, Gawronska-Kozak B. | 01/9/2021 |
| The FoxN1 nu mutation, which abolishes thymic epithelium differentiation, results in the formation of a tubular branched structure according to a typical branching morphogenesis and tubulogenesis developmental pattern. | FoxN1 mediates thymic cortex-medulla differentiation through modifying a developmental pattern based on epithelial tubulogenesis.
Muñoz JJ, Tobajas E, Juara S, Montero S, Zapata AG. | 12/7/2019 |
| Foxn1 expression in keratinocytes is stimulated by hypoxia: further evidence of its role in skin wound healing | Foxn1 expression in keratinocytes is stimulated by hypoxia: further evidence of its role in skin wound healing.
Kur-Piotrowska A, Bukowska J, Kopcewicz MM, Dietrich M, Nynca J, Slowinska M, Gawronska-Kozak B., Free PMC Article | 10/5/2019 |
| Thymopoesis is largely normal in Foxn1+/nu mice. | FoxN1-dependent thymic epithelial cells promote T-cell leukemia development.
Ghezzo MN, Fernandes MT, Pacheco-Leyva I, Rodrigues PM, Machado RS, Araújo MAS, Kalathur RK, Futschik ME, Alves NL, Dos Santos NR. | 06/15/2019 |
| Study report the identification of a highly conserved Foxn1-binding sequence that is located proximal to the beta5t-coding sequence in the mouse genome. This cis-regulatory element is indeed essential for the optimal expression of beta5t in cortical thymic epithelial cells and the optimal production of CD8+ T cells. | Foxn1-β5t transcriptional axis controls CD8(+) T-cell production in the thymus.
Uddin MM, Ohigashi I, Motosugi R, Nakayama T, Sakata M, Hamazaki J, Nishito Y, Rode I, Tanaka K, Takemoto T, Murata S, Takahama Y., Free PMC Article | 11/17/2018 |
| data identify the transcription factor Foxn1 as a potential key epidermal regulator modifying both epidermal and dermal healing processes after cutaneous wounding | Foxn1 and Mmp-9 expression in intact skin and during excisional wound repair in young, adult, and old C57Bl/6 mice.
Kopcewicz MM, Kur-Piotrowska A, Bukowska J, Gimble JM, Gawronska-Kozak B. | 06/30/2018 |
| MicroRNA-205 maintains T cell development following stress by regulating Foxn1 and its two regulated targets, stem cell factor and ccl25, following stress. | MicroRNA-205 Maintains T Cell Development following Stress by Regulating Forkhead Box N1 and Selected Chemokines.
Hoover AR, Dozmorov I, MacLeod J, Du Q, de la Morena MT, Forbess J, Guleserian K, Cleaver OB, van Oers NS., Free PMC Article | 09/30/2017 |
| this study identified Bmp4 as a significant factor for improved maintenance of Foxn1 expression, promotion of thymic epithelial progenitor populations self-renewal and immature epithelial cell differentiation and survival | A novel Foxn1(eGFP/+) mouse model identifies Bmp4-induced maintenance of Foxn1 expression and thymic epithelial progenitor populations.
Barsanti M, Lim JM, Hun ML, Lister N, Wong K, Hammett MV, Lepletier A, Boyd RL, Giudice A, Chidgey AP. | 07/8/2017 |
| results show that Foxn1, and alleles under its control, are expressed in the pre-meiotic male germline, revealing a new tool for germline targeting of genes, and raising important concerns for gender selection when using Foxn1 regulatory elements. | Foxn1[Cre] Expression in the Male Germline.
Shi J, Getun I, Torres B, Petrie HT., Free PMC Article | 06/24/2017 |
| this study shows that critical events in thymic lympho-stromal cross-talk and T cell selection are regulated by Foxn1 | Foxn1 regulates key target genes essential for T cell development in postnatal thymic epithelial cells.
Žuklys S, Handel A, Zhanybekova S, Govani F, Keller M, Maio S, Mayer CE, Teh HY, Hafen K, Gallone G, Barthlott T, Ponting CP, Holländer GA., Free PMC Article | 06/3/2017 |
| sphingolipids and fatty acids associated with a decrease in glycerolipids suggest that the lipidome in mice skin is regulated by the Foxn1 gene | Changing in lipid profile induced by the mutation of Foxn1 gene: A lipidomic analysis of Nude mice skin.
Lanzini J, Dargère D, Regazzetti A, Tebani A, Laprévote O, Auzeil N. | 08/20/2016 |
| Foxn1 transcription factor regulates wound healing of skin through promoting epithelial-mesenchymal transition. | Foxn1 Transcription Factor Regulates Wound Healing of Skin through Promoting Epithelial-Mesenchymal Transition.
Gawronska-Kozak B, Grabowska A, Kur-Piotrowska A, Kopcewicz M., Free PMC Article | 08/6/2016 |
| early differentiation and maturation of cortical and medullary thymic epithelial cells coincides with precise sub-lineage-specific regulation of Foxn1 expression levels. | Foxn1 Is Dynamically Regulated in Thymic Epithelial Cells during Embryogenesis and at the Onset of Thymic Involution.
O'Neill KE, Bredenkamp N, Tischner C, Vaidya HJ, Stenhouse FH, Peddie CD, Nowell CS, Gaskell T, Blackburn CC., Free PMC Article | 07/30/2016 |