| HES1 is required for mouse fetal hematopoiesis. | HES1 is required for mouse fetal hematopoiesis.
Zhu AZ, Ma Z, Wolff EV, Lin Z, Gao ZJ, Li X, Du W., Free PMC Article | 09/6/2024 |
| RIP140 regulates transcription factor HES1 oscillatory expression and mitogenic activity in colon cancer cells. | RIP140 regulates transcription factor HES1 oscillatory expression and mitogenic activity in colon cancer cells.
Sfeir N, Kajdan M, Jalaguier S, Bonnet S, Teyssier C, Pyrdziak S, Yuan R, Bousquet E, Maraver A, Bernex F, Pirot N, Boissière-Michot F, Castet-Nicolas A, Lapierre M, Cavaillès V., Free PMC Article | 06/18/2024 |
| bHLH transcription factors Hes1, Ascl1 and Oligo2 exhibit different expression patterns in the process of physiological electric fields-induced neuronal differentiation. | bHLH transcription factors Hes1, Ascl1 and Oligo2 exhibit different expression patterns in the process of physiological electric fields-induced neuronal differentiation.
Li Z, Li H, Yu X, Zhou J, Dong ZY, Meng X. | 02/6/2024 |
| Early induction of Hes1 by bone morphogenetic protein 9 plays a regulatory role in osteoblastic differentiation of a mesenchymal stem cell line. | Early induction of Hes1 by bone morphogenetic protein 9 plays a regulatory role in osteoblastic differentiation of a mesenchymal stem cell line.
Seong CH, Chiba N, Fredy M, Kusuyama J, Ishihata K, Kibe T, Amir MS, Tada R, Ohnishi T, Nakamura N, Matsuguchi T. | 09/23/2023 |
| Hes1 marks peri-condensation mesenchymal cells that generate both chondrocytes and perichondrial cells in early bone development. | Hes1 marks peri-condensation mesenchymal cells that generate both chondrocytes and perichondrial cells in early bone development.
Matsushita Y, Manabe H, Ohyama T, Nakamura S, Nagata M, Ono W, Ono N., Free PMC Article | 07/7/2023 |
| Differential cell-cycle control by oscillatory versus sustained Hes1 expression via p21. | Differential cell-cycle control by oscillatory versus sustained Hes1 expression via p21.
Maeda Y, Isomura A, Masaki T, Kageyama R. | 06/7/2023 |
| HES1-mediated down-regulation of miR-138 sustains NOTCH1 activation and promotes proliferation and invasion in renal cell carcinoma. | HES1-mediated down-regulation of miR-138 sustains NOTCH1 activation and promotes proliferation and invasion in renal cell carcinoma.
Liu S, Dou L, Miao M, Man X, Wei B, Jiang Z, Ouyang Y, Ozaki T, Yu M, Zhu Y., Free PMC Article | 04/4/2023 |
| Medial prefrontal cortex Notch1 signalling mediates methamphetamine-induced psychosis via Hes1-dependent suppression of GABAB1 receptor expression. | Medial prefrontal cortex Notch1 signalling mediates methamphetamine-induced psychosis via Hes1-dependent suppression of GABA(B1) receptor expression.
Ni T, Zhu L, Wang S, Zhu W, Xue Y, Zhu Y, Ma D, Wang H, Guan F, Chen T., Free PMC Article | 12/10/2022 |
| Context-Dependent Roles of Hes1 in the Adult Pancreas and Pancreatic Tumor Formation. | Context-Dependent Roles of Hes1 in the Adult Pancreas and Pancreatic Tumor Formation.
Marui S, Nishikawa Y, Shiokawa M, Yokode M, Matsumoto S, Muramoto Y, Ota S, Nakamura T, Yoshida H, Okada H, Kuwada T, Matsumori T, Kuriyama K, Fukuda A, Saur D, Aoi T, Uza N, Kodama Y, Chiba T, Seno H. | 11/26/2022 |
| HES1 is a novel downstream modifier of the SHH-GLI3 Axis in the development of preaxial polydactyly. | HES1 is a novel downstream modifier of the SHH-GLI3 Axis in the development of preaxial polydactyly.
Sharma D, Mirando AJ, Leinroth A, Long JT, Karner CM, Hilton MJ., Free PMC Article | 02/19/2022 |
| Hairy and enhancer of split 1 is a primary effector of NOTCH2 signaling and induces osteoclast differentiation and function. | Hairy and enhancer of split 1 is a primary effector of NOTCH2 signaling and induces osteoclast differentiation and function.
Yu J, Schilling L, Eller T, Canalis E., Free PMC Article | 02/19/2022 |
| Hes1 oscillation frequency correlates with activation of neural stem cells. | Hes1 oscillation frequency correlates with activation of neural stem cells.
Kaise T, Kageyama R. | 12/18/2021 |
| TNF-alpha inhibits GDNF levels in Sertoli cells, through a NF-kappaB-dependent, HES1-dependent mechanism. | TNF-α inhibits GDNF levels in Sertoli cells, through a NF-κB-dependent, HES1-dependent mechanism.
Di Persio S, Starace D, Capponi C, Saracino R, Fera S, Filippini A, Vicini E. | 12/4/2021 |
| The NOTCH-HES-1 axis is involved in promoting Th22 cell differentiation. | The NOTCH-HES-1 axis is involved in promoting Th22 cell differentiation.
Zeng C, Shao Z, Wei Z, Yao J, Wang W, Yin L, YangOu H, Xiong D., Free PMC Article | 10/9/2021 |
| Bone morphogenetic protein 9 (BMP9) directly induces Notch effector molecule Hes1 through the SMAD signaling pathway in osteoblasts. | Bone morphogenetic protein 9 (BMP9) directly induces Notch effector molecule Hes1 through the SMAD signaling pathway in osteoblasts.
Seong CH, Chiba N, Kusuyama J, Subhan Amir M, Eiraku N, Yamashita S, Ohnishi T, Nakamura N, Matsuguchi T. | 07/31/2021 |
| Ginsenoside Rg3 Suppresses Epithelial-Mesenchymal Transition via Downregulating Notch-Hes1 Signaling in Colon Cancer Cells. | Ginsenoside Rg3 Suppresses Epithelial-Mesenchymal Transition via Downregulating Notch-Hes1 Signaling in Colon Cancer Cells.
Li X, Liu W, Geng C, Li T, Li Y, Guo Y, Wang C. | 07/17/2021 |
| Notch-Hes1 Signaling Regulates IL-17A(+) gammadelta (+)T Cell Expression and IL-17A Secretion of Mouse Psoriasis-Like Skin Inflammation. | Notch-Hes1 Signaling Regulates IL-17A(+) γδ (+)T Cell Expression and IL-17A Secretion of Mouse Psoriasis-Like Skin Inflammation.
Wang Y, Li X, Xing X, Xue H, Qi R, Ji H, Ma L., Free PMC Article | 07/10/2021 |
| FANCD2 and HES1 suppress inflammation-induced PPAR to prevent haematopoietic stem cell exhaustion. | FANCD2 and HES1 suppress inflammation-induced PPARɣ to prevent haematopoietic stem cell exhaustion.
Wu L, Li X, Lin Q, Chowdhury F, Mazumder MH, Du W., Free PMC Article | 06/26/2021 |
| Visualizing Cell Cycle Phase Organization and Control During Neural Lineage Elaboration. | Visualizing Cell Cycle Phase Organization and Control During Neural Lineage Elaboration.
Urun FR, Moore AW., Free PMC Article | 03/28/2021 |
| Hes1 Is Essential in Proliferating Ductal Cell-Mediated Development of Intrahepatic Cholangiocarcinoma. | Hes1 Is Essential in Proliferating Ductal Cell-Mediated Development of Intrahepatic Cholangiocarcinoma.
Matsumori T, Kodama Y, Takai A, Shiokawa M, Nishikawa Y, Matsumoto T, Takeda H, Marui S, Okada H, Hirano T, Kuwada T, Sogabe Y, Kakiuchi N, Tomono T, Mima A, Morita T, Ueda T, Tsuda M, Yamauchi Y, Kuriyama K, Sakuma Y, Ota Y, Maruno T, Uza N, Marusawa H, Kageyama R, Chiba T, Seno H. | 03/6/2021 |
| Foxi1 inactivation rescues loss of principal cell fate selection in Hes1-deficient kidneys but does not ensure maintenance of principal cell gene expression. | Foxi1 inactivation rescues loss of principal cell fate selection in Hes1-deficient kidneys but does not ensure maintenance of principal cell gene expression.
Mukherjee M, DeRiso J, Janga M, Fogarty E, Surendran K., Free PMC Article | 02/27/2021 |
| Hes1 expression in mature neurons in the adult mouse brain is required for normal behaviors. | Hes1 expression in mature neurons in the adult mouse brain is required for normal behaviors.
Matsuzaki T, Yoshihara T, Ohtsuka T, Kageyama R., Free PMC Article | 10/24/2020 |
| Simultaneous Requirements for Hes1 in Retinal Neurogenesis and Optic Cup-Stalk Boundary Maintenance. | Simultaneous Requirements for Hes1 in Retinal Neurogenesis and Optic Cup-Stalk Boundary Maintenance.
Bosze B, Moon MS, Kageyama R, Brown NL., Free PMC Article | 08/22/2020 |
| robust Hes1 oscillations are required for maintenance and proliferation of NPCs and the normal timing of neurogenesis, thereby regulating brain morphogenesis | Oscillatory expression of Hes1 regulates cell proliferation and neuronal differentiation in the embryonic brain.
Ochi S, Imaizumi Y, Shimojo H, Miyachi H, Kageyama R. | 08/15/2020 |
| we conclude that TLX, by repressing Hes1 expression, counteracts quiescence and NOTCH activation in NSCs, thereby relieving NOTCH-mediated lateral inhibition of proliferation in basal progenitors. | The Orphan Nuclear Receptor TLX Represses Hes1 Expression, Thereby Affecting NOTCH Signaling and Lineage Progression in the Adult SEZ.
Luque-Molina I, Shi Y, Abdullah Y, Monaco S, Hölzl-Wenig G, Mandl C, Ciccolini F., Free PMC Article | 06/13/2020 |