| Potential role of CTSS in AMDImmune modulatory and anti-angiogenic effects of cathepsin S knockdown in ARPE-19 cells. | Potential role of CTSS in AMDImmune modulatory and anti-angiogenic effects of cathepsin S knockdown in ARPE-19 cells.
Preya UH, Sayed S, Nguyen NL, Kim JT. | 08/13/2024 |
| Elevated Cathepsin S Serum Levels in New-Onset Type 1 Diabetes and Autoantibody-Positive Siblings. | Elevated Cathepsin S Serum Levels in New-Onset Type 1 Diabetes and Autoantibody-Positive Siblings.
Frørup C, Jensen MH, Haupt-Jorgensen M, Buschard K, Størling J, Pociot F, Fløyel T. | 07/24/2024 |
| Macrophage-Derived Cathepsin S Remodels the Extracellular Matrix to Promote Liver Fibrogenesis. | Macrophage-Derived Cathepsin S Remodels the Extracellular Matrix to Promote Liver Fibrogenesis.
Zuo T, Xie Q, Liu J, Yang J, Shi J, Kong D, Wang Y, Zhang Z, Gao H, Zeng DB, Wang X, Tao P, Wei W, Wang J, Li Y, Long Q, Li C, Chang L, Ning H, Li Y, Cui C, Ge X, Wu J, Li G, Hong X, Yang X, Dai E, He F, Wu J, Ruan Y, Lu S, Xu P. | 08/23/2023 |
| Granulomatous rosacea in Chinese patients: Clinical-histopathological analysis and pathogenesis exploration. | Granulomatous rosacea in Chinese patients: Clinical-histopathological analysis and pathogenesis exploration.
Jiang Y, Huang Y, Ma G, Liu T, Li Q, Wu H, Li J. | 07/12/2023 |
| Cathepsin S Knockdown Suppresses Endothelial Inflammation, Angiogenesis, and Complement Protein Activity under Hyperglycemic Conditions In Vitro by Inhibiting NF-kappaB Signaling. | Cathepsin S Knockdown Suppresses Endothelial Inflammation, Angiogenesis, and Complement Protein Activity under Hyperglycemic Conditions In Vitro by Inhibiting NF-κB Signaling.
Sayed S, Faruq O, Preya UH, Kim JT., Free PMC Article | 03/31/2023 |
| Cathepsin S are involved in human carotid atherosclerotic disease progression, mainly by mediating phagosomes: bioinformatics and in vivo and vitro experiments. | Cathepsin S are involved in human carotid atherosclerotic disease progression, mainly by mediating phagosomes: bioinformatics and in vivo and vitro experiments.
Wang H, Jiang H, Cheng XW., Free PMC Article | 02/9/2023 |
| Cathepsin S (CTSS) activity in health and disease - A treasure trove of untapped clinical potential. | Cathepsin S (CTSS) activity in health and disease - A treasure trove of untapped clinical potential.
Smyth P, Sasiwachirangkul J, Williams R, Scott CJ. | 01/11/2023 |
| Cathepsin S as an early biomarker for cardiovascular disease in chronic kidney disease patients. | Cathepsin S as an early biomarker for cardiovascular disease in chronic kidney disease patients.
Sonkar SK, Singh PK, Chandra S, Sonkar GK, Bhosale V, Sharma S., Free PMC Article | 10/8/2022 |
| Knockdown of CD44 inhibits proliferation, migration and invasion of osteosarcoma cells accompanied by downregulation of cathepsin S. | Knockdown of CD44 inhibits proliferation, migration and invasion of osteosarcoma cells accompanied by downregulation of cathepsin S.
Kong L, Ji H, Gan X, Cao S, Li Z, Jin Y., Free PMC Article | 03/26/2022 |
| Association of Circulating Cathepsin S and Cardiovascular Disease Among Patients With Type 2 Diabetes: A Cross-Sectional Community-Based Study. | Association of Circulating Cathepsin S and Cardiovascular Disease Among Patients With Type 2 Diabetes: A Cross-Sectional Community-Based Study.
Jing Y, Shi J, Lu B, Zhang W, Yang Y, Wen J, Hu R, Yang Z, Wang X., Free PMC Article | 12/18/2021 |
| Inhibition of cathepsin S attenuates myocardial ischemia/reperfusion injury by suppressing inflammation and apoptosis. | Inhibition of cathepsin S attenuates myocardial ischemia/reperfusion injury by suppressing inflammation and apoptosis.
Peng K, Liu H, Yan B, Meng XW, Song SY, Ji FH, Xia Z. | 09/11/2021 |
| Targeting lysosomal cysteine protease cathepsin S reveals immunomodulatory therapeutic strategy for oxaliplatin-induced peripheral neuropathy. | Targeting lysosomal cysteine protease cathepsin S reveals immunomodulatory therapeutic strategy for oxaliplatin-induced peripheral neuropathy.
Chen SJ, Chen LH, Yeh YM, Lin CK, Lin PC, Huang HW, Shen MR, Lin BW, Lee JC, Lee CC, Lee YF, Chiang HC, Chang JY., Free PMC Article | 08/21/2021 |
| Usefulness of Cathepsin S to Predict Risk for Obstructive Sleep Apnea among Patients with Type 2 Diabetes. | Usefulness of Cathepsin S to Predict Risk for Obstructive Sleep Apnea among Patients with Type 2 Diabetes.
Wen W, Sun H, Yang Y, Jia Y, Fang F, Qin Y, Zhang M, Wei Y., Free PMC Article | 07/31/2021 |
| Decreased serum cathepsin S levels in patients with systemic sclerosis-associated interstitial lung disease. | Decreased serum cathepsin S levels in patients with systemic sclerosis-associated interstitial lung disease.
Toyama S, Yamashita T, Saigusa R, Miura S, Nakamura K, Hirabayashi M, Miyagawa T, Fukui Y, Omatsu J, Yoshizaki A, Sato S, Asano Y. | 06/26/2021 |
| High levels of cathepsin S and cystatin C in patients with fibromyalgia syndrome. | High levels of cathepsin S and cystatin C in patients with fibromyalgia syndrome.
Kocak I, Hizmetli S, Tas A, Karadag A, Zontul C, Silig Y. | 06/12/2021 |
| Novel Opportunities for Cathepsin S Inhibitors in Cancer Immunotherapy by Nanocarrier-Mediated Delivery. | Novel Opportunities for Cathepsin S Inhibitors in Cancer Immunotherapy by Nanocarrier-Mediated Delivery.
Fuchs N, Meta M, Schuppan D, Nuhn L, Schirmeister T., Free PMC Article | 03/28/2021 |
| [Cathepsin S (CTSS) is highly expressed in temozolomide-resistant glioblastoma T98G cells and associated with poor prognosis]. | [Cathepsin S (CTSS) is highly expressed in temozolomide-resistant glioblastoma T98G cells and associated with poor prognosis].
Lyu W, Jia B, Liu W, Guo Q. | 11/21/2020 |
| Cathepsin S Regulates Antigen Processing and T Cell Activity in Non-Hodgkin Lymphoma. | Cathepsin S Regulates Antigen Processing and T Cell Activity in Non-Hodgkin Lymphoma.
Dheilly E, Battistello E, Katanayeva N, Sungalee S, Michaux J, Duns G, Wehrle S, Sordet-Dessimoz J, Mina M, Racle J, Farinha P, Coukos G, Gfeller D, Mottok A, Kridel R, Correia BE, Steidl C, Bassani-Sternberg M, Ciriello G, Zoete V, Oricchio E. | 11/21/2020 |
| Expression of elastolytic cathepsins in human skin and their involvement in age-dependent elastin degradation. | Expression of elastolytic cathepsins in human skin and their involvement in age-dependent elastin degradation.
Panwar P, Hedtke T, Heinz A, Andrault PM, Hoehenwarter W, Granville DJ, Schmelzer CEH, Brömme D. | 10/24/2020 |
| Cathepsin S (CatS) activity in tear fluid seems to be a relevant biomarker for primary Sjogren syndrome (pSS) disease activity, suggesting CatS inhibition may represent a promising treatment strategy in pSS. | Differential effects of specific cathepsin S inhibition in biocompartments from patients with primary Sjögren syndrome.
Hargreaves P, Daoudlarian D, Theron M, Kolb FA, Manchester Young M, Reis B, Tiaden A, Bannert B, Kyburz D, Manigold T., Free PMC Article | 08/15/2020 |
| Transcriptome analysis of alveolar macrophages demonstrated increased cathepsin S levels in pulmonary sarcoidosis. | Cathepsin S, a new serum biomarker of sarcoidosis discovered by transcriptome analysis of alveolar macrophages.
Tanaka H, Yamaguchi E, Asai N, Yokoi T, Nishimura M, Nakao H, Yoneda M, Ohtsuka Y, Konno S, Yamada N., Free PMC Article | 07/18/2020 |
| CTSS interacted with the BRCT domain of BRCA1 and facilitated ubiquitin-mediated proteolytic degradation of BRCA1, which was tightly associated with decreased BRCA1-mediated DNA repair activity. | Regulating BRCA1 protein stability by cathepsin S-mediated ubiquitin degradation.
Kim S, Jin H, Seo HR, Lee HJ, Lee YS., Free PMC Article | 07/4/2020 |
| The present study focused on (a) confirming that mela- tonin effectively inhibits epidermal growth factor (EGF)-induced cell proliferation and cell migration by inhibiting cathepsin S (CTSS) protein expression, and (b) examining the AKT/mTOR pathway and transcription factors (c-Jun/Sp1) involved in the molecular mechanism of cell pro- liferation and migration of ARPE-19 cells. | Melatonin attenuates epidermal growth factor-induced cathepsin S expression in ARPE-19 cells: Implications for proliferative vitreoretinopathy.
Yang SF, Chen YS, Chien HW, Wang K, Lin CL, Chiou HL, Lee CY, Chen PN, Hsieh YH. | 06/13/2020 |
| The activity of Cathepsin S in pulmonary vascular remodeling and degradation of elastin fibers through the disruption of PPARG is pathophysiologically significant in pulmonary arterial hypertension. | Cathepsin S promotes the development of pulmonary arterial hypertension.
Chang CJ, Hsu HC, Ho WJ, Chang GJ, Pang JS, Chen WJ, Huang CC, Lai YJ. | 03/28/2020 |
| CTSS is expressed by bronchial tissue and is elevated in bronchial tissue from subjects with COPD. | Protein Phosphatase 2A Reduces Cigarette Smoke-induced Cathepsin S and Loss of Lung Function.
Doherty DF, Nath S, Poon J, Foronjy RF, Ohlmeyer M, Dabo AJ, Salathe M, Birrell M, Belvisi M, Baumlin N, Kim MD, Weldon S, Taggart C, Geraghty P., Free PMC Article | 02/29/2020 |