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    DPPA2 developmental pluripotency associated 2 [ Homo sapiens (human) ]

    Gene ID: 151871, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Transcription Factor CTCFL Promotes Cell Proliferation, Migration, and Invasion in Gastric Cancer via Activating DPPA2.

    Transcription Factor CTCFL Promotes Cell Proliferation, Migration, and Invasion in Gastric Cancer via Activating DPPA2.
    Yao H, Shao Q, Shao Y., Free PMC Article

    02/5/2022
    Dppa2/4 as a trigger of signaling pathways to promote zygote genome activation by binding to CG-rich region.

    Dppa2/4 as a trigger of signaling pathways to promote zygote genome activation by binding to CG-rich region.
    Li H, Long C, Xiang J, Liang P, Li X, Zuo Y.

    11/22/2021
    SPOP suppresses testicular germ cell tumors progression through ubiquitination and degradation of DPPA2.

    SPOP suppresses testicular germ cell tumors progression through ubiquitination and degradation of DPPA2.
    Wang J, Zhuang H, Zhang H, Li Q, Cao X, Lin Z, Lin T, Chen X, Ni X, Yang J, Zhao Y, Shen L, Wang H, Zhu J, Ye M, Jin X.

    08/7/2021
    High DPPA2 Protein Expression is Associated with Gastric Cancer Metastasis

    DPPA2 Protein Expression is Associated with Gastric Cancer Metastasis.
    Shabestarian H, Ghodsi M, Mallak AJ, Jafarian AH, Montazer M, Forghanifard MM.

    10/8/2016
    results showed that DPPA2 expression was significantly correlated to the depth of tumor invasion and progression of tumor cells through advanced stages in colorectal cancer.

    Diagnostic clinical relevance of developmental pluripotency-associated 2 (DPPA2) in colorectal cancer.
    Ghodsi M, Jafarian AH, Montazer M, Sadeghian MH, Forghanifard MM.

    10/17/2015
    Results identified a new family of pluripotency-related oncogenes consisting of DPPA2 and DPPA4.

    Identification of DPPA4 and DPPA2 as a novel family of pluripotency-related oncogenes.
    Tung PY, Varlakhanova NV, Knoepfler PS., Free PMC Article

    09/20/2014
    A important role of HIWI and DPPA2 in tumorigenesis and also in lymph node metastasis of tumor cells.

    Aberrant expression of DPPA2 and HIWI genes in colorectal cancer and their impacts on poor prognosis.
    Raeisossadati R, Abbaszadegan MR, Moghbeli M, Tavassoli A, Kihara AH, Forghanifard MM.

    08/23/2014
    Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

    Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article

    06/30/2010
    In normal tissues, PLAC1 expression was restricted to the placenta while DPPA2 expression was restricted to the placenta and testis.

    Expression and serum immunoreactivity of developmentally restricted differentiation antigens in epithelial ovarian cancer.
    Tchabo NE, Mhawech-Fauceglia P, Caballero OL, Villella J, Beck AF, Miliotto AJ, Liao J, Andrews C, Lele S, Old LJ, Odunsi K., Free PMC Article

    01/21/2010
    ECSA/DPPA2 is a promising target for antigen-specific immunotherapy in non-small cell lung cancers

    ECSA/DPPA2 is an embryo-cancer antigen that is coexpressed with cancer-testis antigens in non-small cell lung cancer.
    John T, Caballero OL, Svobodová SJ, Kong A, Chua R, Browning J, Fortunato S, Deb S, Hsu M, Gedye CA, Davis ID, Altorki N, Simpson AJ, Chen YT, Monk M, Cebon JS.

    01/21/2010
    Differential expression of the embryo/cancer gene ECSA(DPPA2) in human preimplantation development.

    Differential expression of the embryo/cancer gene ECSA(DPPA2), the cancer/testis gene BORIS and the pluripotency structural gene OCT4, in human preimplantation development.
    Monk M, Hitchins M, Hawes S.

    01/21/2010
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