| Association between COMMD1 gene polymorphism rs11125908 and rheumatoid arthritis in the Cuban population. | Association between COMMD1 gene polymorphism rs11125908 and rheumatoid arthritis in the Cuban population.
Carpio Alvarez M, Cintado Benitez A, Diaz Argudin T, Nodarse Cuni H, Dominguez Horta MDC, Fernández Massó JR. | 07/12/2024 |
| COMMD1, a multi-potent intracellular protein involved in copper homeostasis, protein trafficking, inflammation, and cancer. | COMMD1, a multi-potent intracellular protein involved in copper homeostasis, protein trafficking, inflammation, and cancer.
Weiskirchen R, Penning LC. | 10/16/2021 |
| Long non-coding RNA SNHG5 suppresses the development of acute respiratory distress syndrome by targeting miR-205/COMMD1 axis. | Long non-coding RNA SNHG5 suppresses the development of acute respiratory distress syndrome by targeting miR-205/COMMD1 axis.
Wang J, Zhang Y, Zhang L. | 07/17/2021 |
| Identification of the COMM-domain containing protein 1 as specific binding partner for the guanine-rich RNA sequence binding factor 1. | Identification of the COMM-domain containing protein 1 as specific binding partner for the guanine-rich RNA sequence binding factor 1.
Dumoulin B, Ufer C, Stehling S, Heydeck D, Kuhn H, Sofi S. | 01/9/2021 |
| The screen identified copper metabolism MURR1 domaincontaining 1 (COMMD1) as a novel lamin A binding partner. Colocalization experiments using fluorescent confocal microscopy revealed that COMMD1 colocalized with lamin A in 293 cells. | Identification of COMMD1 as a novel lamin A binding partner.
Jiang Z, Chen W, Zhou J, Peng Q, Zheng H, Yuan Y, Cui H, Zhao W, Sun X, Zhou Z, Liu X., Free PMC Article | 01/4/2020 |
| results suggest that COMMD1 regulates cell proliferation and cell cycle progression by modulating p21 Cip1 levels | COMMD1 regulates cell proliferation and cell cycle progression by modulating p21 Cip1 levels.
Jiang Z, Yuan Y, Zheng H, Cui H, Sun X, Zhao W, Liu X. | 07/6/2019 |
| Sp1 constitutively regulates the basal expression of the COMMD1 gene in human epithelial cell lines. | Transcriptional regulation of HIV-1 host factor COMMD1 by the Sp family.
Kudo E, Taura M, Suico MA, Goto H, Kai H, Okada S. | 08/25/2018 |
| This study has thus revealed a novel nuclear complex of F-actin, DRR1 and COMMD1 that is involved in NF-kappaB degradation and cell cycle suppression in neuroblastoma cells. | A novel nuclear complex of DRR1, F-actin and COMMD1 involved in NF-κB degradation and cell growth suppression in neuroblastoma.
Mu P, Akashi T, Lu F, Kishida S, Kadomatsu K. | 10/28/2017 |
| these results identify COMMD1 and an E2F-metabolic pathway as key regulators of osteoclastogenic responses under pathological inflammatory conditions | Hypoxia-Sensitive COMMD1 Integrates Signaling and Cellular Metabolism in Human Macrophages and Suppresses Osteoclastogenesis.
Murata K, Fang C, Terao C, Giannopoulou EG, Lee YJ, Lee MJ, Mun SH, Bae S, Qiao Y, Yuan R, Furu M, Ito H, Ohmura K, Matsuda S, Mimori T, Matsuda F, Park-Min KH, Ivashkiv LB., Free PMC Article | 09/30/2017 |
| The COMMD1 downregulation by miR-205 promotes tumor development by modulating a positive feedback loop that amplifies inflammatory- and stemness-associated properties of cancer cells. | Downregulation of COMMD1 by miR-205 promotes a positive feedback loop for amplifying inflammatory- and stemness-associated properties of cancer cells.
Yeh DW, Chen YS, Lai CY, Liu YL, Lu CH, Lo JF, Chen L, Hsu LC, Luo Y, Xiang R, Chuang TH., Free PMC Article | 12/31/2016 |
| COMMD1 plays a critical role in the termination of NF-kappaB activity and the control of pro-inflammatory and pro-labor mediators. | Copper metabolism domain-containing 1 represses the mediators involved in the terminal effector pathways of human labour and delivery.
Lappas M. | 12/17/2016 |
| COMMD1 expression is associated with poor prognosis in diffuse large B-cell lymphoma | Deregulation of COMMD1 is associated with poor prognosis in diffuse large B-cell lymphoma.
Taskinen M, Louhimo R, Koivula S, Chen P, Rantanen V, Holte H, Delabie J, Karjalainen-Lindsberg ML, Björkholm M, Fluge Ø, Pedersen LM, Fjordén K, Jerkeman M, Eriksson M, Hautaniemi S, Leppä S., Free PMC Article | 01/30/2016 |
| COMMD1 is identified as a novel regulator of misfolded protein aggregation. | The Copper Metabolism MURR1 domain protein 1 (COMMD1) modulates the aggregation of misfolded protein species in a client-specific manner.
Vonk WI, Kakkar V, Bartuzi P, Jaarsma D, Berger R, Hofker MH, Klomp LW, Wijmenga C, Kampinga HH, van de Sluis B., Free PMC Article | 12/19/2015 |
| COMMD1 is directly linked to early endosomes through its interaction with a protein complex containing CCDC22, CCDC93, and C16orf62. | COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A.
Phillips-Krawczak CA, Singla A, Starokadomskyy P, Deng Z, Osborne DG, Li H, Dick CJ, Gomez TS, Koenecke M, Zhang JS, Dai H, Sifuentes-Dominguez LF, Geng LN, Kaufmann SH, Hein MY, Wallis M, McGaughran J, Gecz J, Sluis Bv, Billadeau DD, Burstein E., Free PMC Article | 08/22/2015 |
| COMMD1 is acetylated by p300 and that acetylation protects COMMD1 from XIAP-mediated proteosomal degradation | p300-mediated acetylation of COMMD1 regulates its stability, and the ubiquitylation and nucleolar translocation of the RelA NF-κB subunit.
O'Hara A, Simpson J, Morin P, Loveridge CJ, Williams AC, Novo SM, Stark LA., Free PMC Article | 08/15/2015 |
| IkappaB-alpha protein was stabilized by COMMD1, which attenuated NF-kappaB signaling during Toll-like receptor ligand and tumor necrosis factor alpha treatment and enhanced HIV-1 latency in latently HIV-1-infected cells. | COMMD1/Murr1 reinforces HIV-1 latent infection through IκB-α stabilization.
Taura M, Kudo E, Kariya R, Goto H, Matsuda K, Hattori S, Vaeteewoottacharn K, McDonald F, Suico MA, Shuto T, Kai H, Okada S., Free PMC Article | 04/25/2015 |
| These data demonstrate the anti-inflammatory properties of COMMD1 in bronchial epithelial cells and open new therapeutic avenues in cystic fibrosis. | COMMD1 modulates noxious inflammation in cystic fibrosis.
de Becdelièvre A, Rocca J, Aissat A, Drévillon L, Moutereau S, Le Gouvello S, Hinzpeter A, Tarze A, Fanen P. | 08/30/2014 |
| Placental COMMD1 expression is increased in women with severe preeclampsia compared to that found in women with normal pregnancies. | Expression and localization of COMMD1 proteins in human placentas from women with preeclampsia.
Kwon HS, Park SH, Hwang HS, Sohn IS, Kim SN., Free PMC Article | 01/11/2014 |
| The role of COMMD1 in copper metabolism and it structure and function are discussed. | COMMD1 and ion transport proteins: what is the COMMection? Focus on "COMMD1 interacts with the COOH terminus of NKCC1 in Calu-3 airway epithelial cells to modulate NKCC1 ubiquitination".
McDonald FJ. | 09/21/2013 |
| The results indicate a role for COMMD1 in the regulation of NKCC1 membrane expression and ubiquitination. | COMMD1 interacts with the COOH terminus of NKCC1 in Calu-3 airway epithelial cells to modulate NKCC1 ubiquitination.
Smith L, Litman P, Liedtke CM., Free PMC Article | 09/21/2013 |
| No major role can be attributed to Atox1 and COMMD in the pathophysiology or clinical variation of Wilson disease. | Molecular analysis of Wilson patients: direct sequencing and MLPA analysis in the ATP7B gene and Atox1 and COMMD1 gene analysis.
Bost M, Piguet-Lacroix G, Parant F, Wilson CM. | 10/20/2012 |
| Clusterin and COMMD1 independently regulate degradation of the mammalian copper ATPases ATP7A and ATP7B. | Clusterin and COMMD1 independently regulate degradation of the mammalian copper ATPases ATP7A and ATP7B.
Materia S, Cater MA, Klomp LW, Mercer JF, La Fontaine S., Free PMC Article | 03/17/2012 |
| COMMD1 (copper metabolism MURR1 domain-containing protein 1) regulates Cullin RING ligases by preventing CAND1 (Cullin-associated Nedd8-dissociated protein 1) binding. | COMMD1 (copper metabolism MURR1 domain-containing protein 1) regulates Cullin RING ligases by preventing CAND1 (Cullin-associated Nedd8-dissociated protein 1) binding.
Mao X, Gluck N, Chen B, Starokadomskyy P, Li H, Maine GN, Burstein E., Free PMC Article | 11/26/2011 |
| These results suggest that COMMD1 downregulates deltaENaC activity by reducing deltaENaC surface expression through promoting internalization of surface deltaENaC to an intracellular recycling pool, possibly via enhanced ubiquitination. | COMMD1 regulates the delta epithelial sodium channel (δENaC) through trafficking and ubiquitination.
Chang T, Ke Y, Ly K, McDonald FJ. | 10/1/2011 |
| Data show that COMMD1 interacts with CFTR. This interaction promotes CFTR cell surface expression as assessed by biotinylation experiments in heterologously expressing cells through regulation of CFTR ubiquitination. | COMMD1-mediated ubiquitination regulates CFTR trafficking.
Drévillon L, Tanguy G, Hinzpeter A, Arous N, de Becdelièvre A, Aissat A, Tarze A, Goossens M, Fanen P., Free PMC Article | 08/27/2011 |