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    LINC00662 long intergenic non-protein coding RNA 662 [ Homo sapiens (human) ]

    Gene ID: 148189, updated on 17-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    LINC00662 Promotes Aggressive Traits by Modulating OCT4 Expression through miR-335-5p in Gallbladder Cancer Cells.

    LINC00662 Promotes Aggressive Traits by Modulating OCT4 Expression through miR-335-5p in Gallbladder Cancer Cells.
    Pérez-Moreno P, Riquelme I, Bizama C, Vergara-Gómez L, Tapia JC, Brebi P, García P, Roa JC., Free PMC Article

    07/5/2024
    LINC00662 promotes melanoma progression by competitively binding miR-107 and activating the beta-catenin signaling pathway.

    LINC00662 promotes melanoma progression by competitively binding miR-107 and activating the β-catenin signaling pathway.
    Luo M, Lei R, Zhao Q, Shen Y, He Z, Xu J., Free PMC Article

    01/9/2024
    The role and mechanisms of long non-coding RNA LINC00662 in promoting the proliferation, migration, and angiogenesis of BGC-823 and HGC-27 cells and the subsequent effect on the progression of gastric cancer.

    The role and mechanisms of long non-coding RNA LINC00662 in promoting the proliferation, migration, and angiogenesis of BGC-823 and HGC-27 cells and the subsequent effect on the progression of gastric cancer.
    Xia X, Zhang G, Wang T, Ji M.

    05/5/2023
    METTL3/LINC00662/miR-186-5p feedback loop regulates docetaxel resistance in triple negative breast cancer.

    METTL3/LINC00662/miR-186-5p feedback loop regulates docetaxel resistance in triple negative breast cancer.
    Jing L, Lan L, Mingxin Z, Zhaofeng Z., Free PMC Article

    10/15/2022
    LINC00662 Promotes Proliferation and Invasion and Inhibits Apoptosis of Glioma Cells Through miR-483-3p/SOX3 Axis.

    LINC00662 Promotes Proliferation and Invasion and Inhibits Apoptosis of Glioma Cells Through miR-483-3p/SOX3 Axis.
    Yuan L, Zhang P, Lu Y, Zhang A, Chen X.

    06/25/2022
    LINC00662 facilitates osteosarcoma progression via sponging miR-103a-3p and regulating SIK2 expression.

    LINC00662 facilitates osteosarcoma progression via sponging miR-103a-3p and regulating SIK2 expression.
    Huang J, Lin F, Xu C, Xu Y.

    03/26/2022
    Long intergenic non-protein coding RNA 662 accelerates the progression of gastric cancer through up-regulating centrosomal protein 55 by sponging microRNA-195-5p.

    Long intergenic non-protein coding RNA 662 accelerates the progression of gastric cancer through up-regulating centrosomal protein 55 by sponging microRNA-195-5p.
    Tao F, Qi L, Liu G., Free PMC Article

    03/12/2022
    A positive feedback loop of LINC00662 and STAT3 promotes malignant phenotype of glioma.

    A positive feedback loop of LINC00662 and STAT3 promotes malignant phenotype of glioma.
    Ji W, Jiao J, Cheng C, Xiao Y, Shao J, Liu H.

    01/22/2022
    Silencing linc00662 inhibits cell proliferation and colony formation of lung cancer cells via regulating the miR-145-5p-PAFAH1B2 axis.

    Silencing linc00662 inhibits cell proliferation and colony formation of lung cancer cells via regulating the miR-145-5p-PAFAH1B2 axis.
    Xu ZY, Peng J, Shi ZZ, Chen XL, Cheng HZ, Wang H, Wang Y, Wang GP, Jiang W, Peng H.

    10/2/2021
    LINC00662 modulates cervical cancer cell proliferation, invasion, and apoptosis via sponging miR-103a-3p and upregulating PDK4.

    LINC00662 modulates cervical cancer cell proliferation, invasion, and apoptosis via sponging miR-103a-3p and upregulating PDK4.
    Liu Y, Qiu S, Zheng X, Qiu Y, Yao S, Ge Y, Zhou C.

    08/21/2021
    Exosomal long non-coding RNA LINC00662 promotes non-small cell lung cancer progression by miR-320d/E2F1 axis.

    Exosomal long non-coding RNA LINC00662 promotes non-small cell lung cancer progression by miR-320d/E2F1 axis.
    Lv X, Lian Y, Liu Z, Xiao J, Zhang D, Yin X., Free PMC Article

    07/24/2021
    LINC00662 Promotes Oral Squamous Cell Carcinoma Cell Growth and Metastasis through miR-144-3p/EZH2 Axis.

    LINC00662 Promotes Oral Squamous Cell Carcinoma Cell Growth and Metastasis through miR-144-3p/EZH2 Axis.
    Yao Y, Liu Y, Jin F, Meng Z., Free PMC Article

    07/17/2021
    TRA2A-induced upregulation of LINC00662 regulates blood-brain barrier permeability by affecting ELK4 mRNA stability in Alzheimer's microenvironment.

    TRA2A-induced upregulation of LINC00662 regulates blood-brain barrier permeability by affecting ELK4 mRNA stability in Alzheimer's microenvironment.
    Liu Q, Zhu L, Liu X, Zheng J, Liu Y, Ruan X, Cao S, Cai H, Li Z, Xue Y., Free PMC Article

    07/10/2021
    LINC00662 contributes to the progression and the radioresistance of cervical cancer by regulating miR-497-5p and CDC25A.

    LINC00662 contributes to the progression and the radioresistance of cervical cancer by regulating miR-497-5p and CDC25A.
    Wei J, Wang L, Sun Y, Bao Y.

    05/29/2021
    LINC00662 promotes cell proliferation, migration and invasion of melanoma by sponging miR-890 to upregulate ELK3.

    LINC00662 promotes cell proliferation, migration and invasion of melanoma by sponging miR-890 to upregulate ELK3.
    Xia XQ, Lu WL, Ye YY, Chen J.

    05/8/2021
    Long non-coding RNA LINC00662 promotes proliferation and migration of breast cancer cells via regulating the miR-497-5p/EglN2 axis.

    Long non-coding RNA LINC00662 promotes proliferation and migration of breast cancer cells via regulating the miR-497-5p/EglN2 axis.
    Cheng L, Xing Z, Zhang P, Xu W.

    02/20/2021
    LINC00662 triggers malignant progression of chordoma by the activation of RNF144B via targeting miR-16-5p.

    LINC00662 triggers malignant progression of chordoma by the activation of RNF144B via targeting miR-16-5p.
    Wang CB, Wang Y, Wang JJ, Guo XL.

    02/13/2021
    Long noncoding RNA LINC00662 promotes M2 macrophage polarization and hepatocellular carcinoma progression via activating Wnt/beta-catenin signaling.

    Long noncoding RNA LINC00662 promotes M2 macrophage polarization and hepatocellular carcinoma progression via activating Wnt/β-catenin signaling.
    Tian X, Wu Y, Yang Y, Wang J, Niu M, Gao S, Qin T, Bao D., Free PMC Article

    02/6/2021
    [Long noncoding RNA Linc00662 promotes the tumorigenesis of prostate cancer cells].

    [Long noncoding RNA Linc00662 promotes the tumorigenesis of prostate cancer cells].
    Yao ZF, Pan ZY, Yao YW, Chen JF.

    01/30/2021
    Long noncoding RNA LINC00662-miR-15b-5p mediated GPR120 dysregulation contributes to osteoarthritis.

    Long noncoding RNA LINC00662-miR-15b-5p mediated GPR120 dysregulation contributes to osteoarthritis.
    Lu M, Zhou E.

    01/2/2021
    Long noncoding RNA LINC00662 functions as miRNA sponge to promote the prostate cancer tumorigenesis through targeting miR-34a.

    Long noncoding RNA LINC00662 functions as miRNA sponge to promote the prostate cancer tumorigenesis through targeting miR-34a.
    Li N, Zhang LY, Qiao YH, Song RJ.

    09/19/2020
    LINC00662 promotes glycolysis and cell survival by regulating miR- 375/HIF-1alpha axis in ovarian cancer.

    LINC00662 promotes glycolysis and cell survival by regulating miR- 375/HIF-1α axis in ovarian cancer.
    Tao LM, Gong YF, Yang HM, Pei JH, Zhao XJ, Liu SS.

    08/29/2020
    the important role of the LINC00662/miR-340-5p/ROCK1 axis in regulating the malignant behavior of AML cells

    High expression of long intergenic non-coding RNA LINC00662 contributes to malignant growth of acute myeloid leukemia cells by upregulating ROCK1 via sponging microRNA-340-5p.
    Liu Y, Gao X, Tian X.

    02/1/2020
    critical role for the LINC00662-miR-497-5p-YAP1 axis in gastric cancer cell growth

    LINC00662 promotes gastric cancer cell growth by modulating the Hippo-YAP1 pathway.
    Liu Z, Yao Y, Huang S, Li L, Jiang B, Guo H, Lei W, Xiong J, Deng J.

    05/18/2019
    Data suggest that overexpression of Linc00662 enhances lung cancer cell metastasis and cancer stem cell characteristics; these characteristics seem to involve interaction of Linc00662 with LIN28 in lung cancer cells; lung cancer patients with higher Linc00662 expression levels exhibit lower overall survival rate than patients with lower Linc00662 expression levels. (LIN28 = RNA-binding protein LIN-28)

    Long non-coding RNA Linc00662 promotes cell invasion and contributes to cancer stem cell-like phenotypes in lung cancer cells.
    Gong W, Su Y, Liu Y, Sun P, Wang X.

    01/12/2019
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