| Kinesin Family Member B18 Is Related to Gastric Mucin Phenotype and Contributes to Gastric Cancer Progression by Regulating Epithelial-Mesenchymal Transition. | Kinesin Family Member B18 Is Related to Gastric Mucin Phenotype and Contributes to Gastric Cancer Progression by Regulating Epithelial-Mesenchymal Transition.
Ishikawa A, Yasumatsu R, Fukui T, Kido A, Katsuya N, Sentani K, Kuraoka K, Oue N, Suzuki T, Oka S, Kotachi T, Tanabe K, Ohdan H, Ashktorab H, Smoot D, Yasui W. | 04/8/2024 |
| Differential Expression of KIF18B in Gastric Cancer and Its Role in Chemotherapy Sensitivity. | Differential Expression of KIF18B in Gastric Cancer and Its Role in Chemotherapy Sensitivity.
Gan LH, Yao L, Yan JH, Huang YQ, Zheng L, Liu P, Lei L. | 03/7/2024 |
| Upregulation of KIF18B facilitates malignant phenotype of esophageal squamous cell carcinoma by activating CDCA8/mTORC1 pathway. | Upregulation of KIF18B facilitates malignant phenotype of esophageal squamous cell carcinoma by activating CDCA8/mTORC1 pathway.
Xie J, Wang B, Luo W, Li C, Jia X., Free PMC Article | 10/15/2022 |
| miR-139-3p/Kinesin family member 18B axis suppresses malignant progression of gastric cancer. | miR-139-3p/Kinesin family member 18B axis suppresses malignant progression of gastric cancer.
Ke H, Wu S, Zhang Y, Zhang G., Free PMC Article | 03/26/2022 |
| Silencing of KIF18B restricts proliferation and invasion and enhances the chemosensitivity of breast cancer via modulating Akt/GSK-3beta/beta-catenin pathway. | Silencing of KIF18B restricts proliferation and invasion and enhances the chemosensitivity of breast cancer via modulating Akt/GSK-3β/β-catenin pathway.
Jiang J, Liu T, He X, Ma W, Wang J, Zhou Q, Li M, Yu S. | 02/19/2022 |
| The nuclear kinesin KIF18B promotes 53BP1-mediated DNA double-strand break repair. | The nuclear kinesin KIF18B promotes 53BP1-mediated DNA double-strand break repair.
Luessing J, Sakhteh M, Sarai N, Frizzell L, Tsanov N, Ramberg KO, Maretto S, Crowley PB, Lowndes NF. | 02/12/2022 |
| KIF18b-dependent hypomethylation of PARPBP gene promoter enhances oxaliplatin resistance in colorectal cancer. | KIF18b-dependent hypomethylation of PARPBP gene promoter enhances oxaliplatin resistance in colorectal cancer.
Hong B, Lu R, Lou W, Bao Y, Qiao L, Hu Y, Liu K, Chen J, Bao D, Ye M, Fang Z, Gong C, Zhang X. | 11/27/2021 |
| Kinesin family member 18B regulates the proliferation and invasion of human prostate cancer cells. | Kinesin family member 18B regulates the proliferation and invasion of human prostate cancer cells.
Wu YP, Ke ZB, Zheng WC, Chen YH, Zhu JM, Lin F, Li XD, Chen SH, Cai H, Zheng QS, Wei Y, Xue XY, Xu N., Free PMC Article | 10/16/2021 |
| KIF18B promotes tumor progression in osteosarcoma by activating beta-catenin. | KIF18B promotes tumor progression in osteosarcoma by activating β-catenin.
Gao T, Yu L, Fang Z, Liu J, Bai C, Li S, Xue R, Zhang L, Tan Z, Fan Z., Free PMC Article | 10/9/2021 |
| KIF18B as a regulator in tumor microenvironment accelerates tumor progression and triggers poor outcome in hepatocellular carcinoma. | KIF18B as a regulator in tumor microenvironment accelerates tumor progression and triggers poor outcome in hepatocellular carcinoma.
Qiu MJ, Zhang L, Chen YB, Zhu LS, Zhang B, Li QT, Yang SL, Xiong ZF. | 10/2/2021 |
| Silencing KIF18B enhances radiosensitivity: identification of a promising therapeutic target in sarcoma. | Silencing KIF18B enhances radiosensitivity: identification of a promising therapeutic target in sarcoma.
Liu W, Yu Z, Tang H, Wang X, Zhang B, Zhao J, Liu X, Zhang J, Wei M., Free PMC Article | 08/7/2021 |
| Bioinformatics Analysis Suggests the Combined Expression of AURKB and KIF18B Being an Important Event in the Development of Clear Cell Renal Cell Carcinoma. | Bioinformatics Analysis Suggests the Combined Expression of AURKB and KIF18B Being an Important Event in the Development of Clear Cell Renal Cell Carcinoma.
Liu Q, Zhang X, Tang H, Liu J, Fu C, Sun M, Zhao L, Wei M, Yu Z, Wang P. | 04/3/2021 |
| KIF18B promotes the proliferation of pancreatic ductal adenocarcinoma via activating the expression of CDCA8. | KIF18B promotes the proliferation of pancreatic ductal adenocarcinoma via activating the expression of CDCA8.
Li B, Liu B, Zhang X, Liu H, He L. | 03/13/2021 |
| KIF18B promotes hepatocellular carcinoma progression through activating Wnt/beta-catenin-signaling pathway. | KIF18B promotes hepatocellular carcinoma progression through activating Wnt/β-catenin-signaling pathway.
Yang B, Wang S, Xie H, Wang C, Gao X, Rong Y, Liu Z, Lu Y. | 03/6/2021 |
| Role of kif2c, A Gene Related to ALL Relapse, in Embryonic Hematopoiesis in Zebrafish. | Role of kif2c, A Gene Related to ALL Relapse, in Embryonic Hematopoiesis in Zebrafish.
Oh CK, Kang JW, Lee Y, Myung K, Ha M, Kang J, Kwon EJ, Kim Y, Oh SO, Heo HJ, Kim S, Kim YH., Free PMC Article | 02/6/2021 |
| KIF18B might promote lung adenocarcinoma cell proliferation, migration, and invasion by activating Rac1 and mediating the AKT/mTOR signaling pathway. | KIF18B as a regulator in microtubule movement accelerates tumor progression and triggers poor outcome in lung adenocarcinoma.
Ji Z, Pan X, Shang Y, Ni DT, Wu FL. | 04/18/2020 |
| KIF18B is highly expressed in cutaneous melanoma and this overexpression is correlated with a worse prognosis. | Kinesin family member 18B: A contributor and facilitator in the proliferation and metastasis of cutaneous melanoma.
Yan H, Zhu C, Zhang L. | 01/18/2020 |
| we demonstrate that Kif18b shortens microtubules by increasing the catastrophe rate of dynamic microtubules. Overall, our work reveals that Kif18b uses its motile properties to reach microtubule ends, where it regulates astral microtubule length to ensure spindle centering. | Microtubule end tethering of a processive kinesin-8 motor Kif18b is required for spindle positioning.
McHugh T, Gluszek AA, Welburn JPI., Free PMC Article | 05/25/2019 |
| Kif18B is only modestly processive and that the motor switches frequently between directed and diffusive modes of motility. | Biased Brownian motion as a mechanism to facilitate nanometer-scale exploration of the microtubule plus end by a kinesin-8.
Shin Y, Du Y, Collier SE, Ohi MD, Lang MJ, Ohi R., Free PMC Article | 10/17/2015 |
| High KIF18B expression is associated with neoplasms. | Translating bioinformatics in oncology: guilt-by-profiling analysis and identification of KIF18B and CDCA3 as novel driver genes in carcinogenesis.
Itzel T, Scholz P, Maass T, Krupp M, Marquardt JU, Strand S, Becker D, Staib F, Binder H, Roessler S, Wang XW, Thorgeirsson S, Müller M, Galle PR, Teufel A., Free PMC Article | 06/20/2015 |
| Kif18B is a new microtubule dynamics regulatory protein that interacts with EB1 to control astral microtubule length | Kif18B interacts with EB1 and controls astral microtubule length during mitosis.
Stout JR, Yount AL, Powers JA, Leblanc C, Ems-McClung SC, Walczak CE., Free PMC Article | 12/31/2011 |
| Results uncover a novel role for Aurora A/B kinases in regulating spindle MT dynamics through Kif18b-MCAK and suggest that the Kif18b-MCAK complex constitutes the major MT plus-end depolymerizing activity in mitotic cells. | A complex of Kif18b and MCAK promotes microtubule depolymerization and is negatively regulated by Aurora kinases.
Tanenbaum ME, Macurek L, van der Vaart B, Galli M, Akhmanova A, Medema RH. | 12/17/2011 |
| the expression of KIF18B is regulated in a cell cycle-dependent manner and therefore may play an important role(s) in cell division. | Cell cycle-regulated expression and subcellular localization of a kinesin-8 member human KIF18B.
Lee YM, Kim E, Park M, Moon E, Ahn SM, Kim W, Hwang KB, Kim YK, Choi W, Kim W. | 10/23/2010 |