CD300f signalling induces inhibitory human monocytes/macrophages. | CD300f signalling induces inhibitory human monocytes/macrophages. Sutherland SIM, Ju X, Silveira PA, Kupresanin F, Horvath LG, Clark GJ. | 07/13/2023 |
CD300a and CD300f molecules regulate the function of leukocytes. | CD300a and CD300f molecules regulate the function of leukocytes. Cao Y, Ao T, Wang X, Wei W, Fan J, Tian X. | 06/5/2021 |
Differential Lipid Recognition by Mouse versus Human CD300f, Inhibiting Passive Cutaneous Anaphylaxis, Depends on a Single Amino Acid Substitution in its Immunoglobulin-Like Domain. | Differential Lipid Recognition by Mouse versus Human CD300f, Inhibiting Passive Cutaneous Anaphylaxis, Depends on a Single Amino Acid Substitution in its Immunoglobulin-Like Domain. Izawa K, Kaitani A, Ando T, Maehara A, Nagamine M, Yamada H, Ando T, Ide T, Matsuzawa M, Okamoto Y, Yin E, Fukase S, Wang H, Kamei A, Uchida S, Maeda K, Nakano N, Uchida K, Tamura N, Ikeda K, Ebihara N, Shimizu T, Voehringer D, Roers A, Ogawa H, Okumura K, Kitaura J. | 11/21/2020 |
Single-nucleotide polymorphism in CD300f gene is associated with major depressive disorder. | CD300f immunoreceptor is associated with major depressive disorder and decreased microglial metabolic fitness. Lago N, Kaufmann FN, Negro-Demontel ML, Alí-Ruiz D, Ghisleni G, Rego N, Arcas-García A, Vitureira N, Jansen K, Souza LM, Silva RA, Lara DR, Pannunzio B, Abin-Carriquiry JA, Amo-Aparicio J, Martin-Otal C, Naya H, McGavern DB, Sayós J, López-Vales R, Kaster MP, Peluffo H., Free PMC Article | 07/11/2020 |
ceramide-CD300f interaction inhibits neutrophil recruitment to the sites of Gram-negative bacterial skin infections in mice. | Role of the Ceramide-CD300f Interaction in Gram-Negative Bacterial Skin Infections. Maehara A, Kaitani A, Izawa K, Shiba E, Nagamine M, Takamori A, Isobe M, Uchida S, Uchida K, Ando T, Maeda K, Nakano N, Voehringer D, Roers A, Shimizu T, Ogawa H, Okumura K, Kitamura T, Kitaura J. | 05/18/2019 |
this study demonstrates the role of CD300f in governing innate immune eosinophil activities in pediatric Crohn's disease patients and in active ulcerative colitis patients | A key requirement for CD300f in innate immune responses of eosinophils in colitis. Moshkovits I, Reichman H, Karo-Atar D, Rozenberg P, Zigmond E, Haberman Y, Ben Baruch-Morgenstern N, Lampinen M, Carlson M, Itan M, Denson LA, Varol C, Munitz A. | 10/14/2017 |
findings suggest that two rare heterozygous truncating variations (RPS24 Q191X and CD300LF P261fsX266) are risk candidates for autism spectrum disorder. | Rare heterozygous truncating variations and risk of autism spectrum disorder: Whole-exome sequencing of a multiplex family and follow-up study in a Japanese population. Inoue E, Watanabe Y, Egawa J, Sugimoto A, Nunokawa A, Shibuya M, Igeta H, Someya T. | 04/30/2016 |
CD300 molecules are all expressed by DC; CD300b, d, e and f are restricted to different subpopulations of the myeloid DC lineage. They have been shown to regulate DC function both in vitro and in vivo. | CD300 molecule regulation of human dendritic cell functions. Gasiorowski RE, Ju X, Hart DN, Clark GJ. | 08/10/2013 |
The data suggest that the neuroprotective role of CD300f would be the result of a complex network of cell interactions. | Overexpression of the immunoreceptor CD300f has a neuroprotective role in a model of acute brain injury. Peluffo H, Alí-Ruiz D, Ejarque-Ortíz A, Heras-Alvarez V, Comas-Casellas E, Martínez-Barriocanal A, Kamaid A, Alvarez-Errico D, Negro ML, Lago N, Schwartz S Jr, Villaverde A, Sayós J., Free PMC Article | 08/18/2012 |
peptides containing ITIM-like sequences of IREM-1 (CD300F) differentially regulate MyD88 and TRIF-mediated TLR signalling | Synthetic peptides containing ITIM-like sequences of IREM-1 (CD300F) differentially regulate MyD88 and TRIF-mediated TLR signalling through activation of SHP and/or PI3K. Lee SM, Suk K, Lee WH., Free PMC Article | 03/24/2012 |
CD300f blocked the activation of cells induced by all TLR ligands | CD300a and CD300f differentially regulate the MyD88 and TRIF-mediated TLR signalling pathways through activation of SHP-1 and/or SHP-2 in human monocytic cell lines. Kim EJ, Lee SM, Suk K, Lee WH., Free PMC Article | 03/17/2012 |
Data indicate that CD300F is an active regulator of TLR-mediated macrophage activation through association with SHP-1 involving MyD88 and/or TRIF. | CD300F blocks both MyD88 and TRIF-mediated TLR signaling through activation of Src homology region 2 domain-containing phosphatase 1. Lee SM, Kim EJ, Suk K, Lee WH. | 08/13/2011 |
Findings indicate that IREM-1 exerted its inhibitory effect on BAFF-medicated signalling through ITIM-mediated regulation of ERK activities in THP-1 cells. | Immune receptor expressed on myeloid cells 1 (IREM-1) inhibits B cell activation factor (BAFF)-mediated inflammatory regulation of THP-1 cells through modulation of the activities of extracellular regulated kinase (ERK). Lee SM, Nam YP, Suk K, Lee WH., Free PMC Article | 02/5/2011 |
Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) | Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study. Danik JS, Paré G, Chasman DI, Zee RY, Kwiatkowski DJ, Parker A, Miletich JP, Ridker PM., Free PMC Article | 01/20/2010 |
reveal a putative functional duality of the IREM-1 myeloid cell receptor | The IREM-1 (CD300f) inhibitory receptor associates with the p85alpha subunit of phosphoinositide 3-kinase. Alvarez-Errico D, Sayós J, López-Botet M. | 01/21/2010 |
IgSF13 was identified from dendritic cells; preferentially expressed in myelo-monocytic cells, including monocytes, monocyte-derived DC and monocyte-related cell lines; may be involved in the negative regulation of specific leukocyte population [IgSF13] | IgSF13, a novel human inhibitory receptor of the immunoglobulin superfamily, is preferentially expressed in dendritic cells and monocytes. Sui L, Li N, Liu Q, Zhang W, Wan T, Wang B, Luo K, Sun H, Cao X. | 01/21/2010 |
a novel inhibitory receptor of the Ig superfamily in myeloid cells. (IREM-1 = immune receptor expressed on myeloid cells-1) | IREM-1 is a novel inhibitory receptor expressed by myeloid cells. Alvarez-Errico D, Aguilar H, Kitzig F, Brckalo T, Sayós J, López-Botet M. | 01/21/2010 |