| Long noncoding RNA HIKER regulates erythropoiesis in Monge's disease via CSNK2B. | Long noncoding RNA HIKER regulates erythropoiesis in Monge's disease via CSNK2B.
Azad P, Zhou D, Tu HC, Villafuerte FC, Traver D, Rana TM, Haddad GG., Free PMC Article | 06/5/2023 |
| CSNK2B modulates IRF1 binding to functional DNA elements and promotes basal and agonist-induced antiviral signaling. | CSNK2B modulates IRF1 binding to functional DNA elements and promotes basal and agonist-induced antiviral signaling.
Matsumoto M, Modliszewski JL, Shinozaki K, Maezawa R, Perez VM, Ishikawa Y, Suzuki R, McKnight KL, Masaki T, Hirai-Yuki A, Kohara M, Lemon SM, Selitsky SR, Yamane D., Free PMC Article | 05/23/2023 |
| MicroRNA-1205 Suppresses Hepatocellular Carcinoma Cell Proliferation via a CSNK2B/CDK4 Axis. | MicroRNA-1205 Suppresses Hepatocellular Carcinoma Cell Proliferation via a CSNK2B/CDK4 Axis.
Li X, Xie S, Xia Q, Yan J, Chen S, Shen J., Free PMC Article | 01/14/2023 |
| Clinical and genetic analysis of six Chinese children with Poirier-Bienvenu neurodevelopmental syndrome caused by CSNK2B mutation. | Clinical and genetic analysis of six Chinese children with Poirier-Bienvenu neurodevelopmental syndrome caused by CSNK2B mutation.
Yang S, Wu L, Liao H, Lu X, Zhang X, Kuang X, Yang L. | 02/5/2022 |
| CSNK2B: A broad spectrum of neurodevelopmental disability and epilepsy severity. | CSNK2B: A broad spectrum of neurodevelopmental disability and epilepsy severity.
Ernst ME, Baugh EH, Thomas A, Bier L, Lippa N, Stong N, Mulhern MS, Kushary S, Akman CI, Heinzen EL, Yeh R, Bi W, Hanchard NA, Burrage LC, Leduc MS, Chong JSC, Bend R, Lyons MJ, Lee JA, Suwannarat P, Brilstra E, Simon M, Koopmans M, van Binsbergen E, Groepper D, Fleischer J, Nava C, Keren B, Mignot C, Mathieu S, Mancini GMS, Madan-Khetarpal S, Infante EM, Bluvstein J, Seeley A, Bachman K, Klee EW, Schultz-Rogers LE, Hasadsri L, Barnett S, Ellingson MS, Ferber MJ, Narayanan V, Ramsey K, Rauch A, Joset P, Steindl K, Sheehan T, Poduri A, Vasquez A, Ruivenkamp C, White SM, Pais L, Monaghan KG, Goldstein DB, Sands TT, Aggarwal V., Free PMC Article | 10/16/2021 |
| Overexpression of NELFE contributes to gastric cancer progression via Wnt/beta-catenin signaling-mediated activation of CSNK2B expression. | Overexpression of NELFE contributes to gastric cancer progression via Wnt/β-catenin signaling-mediated activation of CSNK2B expression.
Yu S, Li L, Cai H, He B, Gao Y, Li Y., Free PMC Article | 09/11/2021 |
| Poirier-Bienvenu neurodevelopmental syndrome: A report of a patient with a pathogenic variant in CSNK2B with abnormal linear growth. | Poirier-Bienvenu neurodevelopmental syndrome: A report of a patient with a pathogenic variant in CSNK2B with abnormal linear growth.
Selvam P, Jain A, Cheema A, Atwal H, Forghani I, Atwal PS. | 07/10/2021 |
| Protein kinase CK2 contributes to placental development: physiological and pathological implications. | Protein kinase CK2 contributes to placental development: physiological and pathological implications.
Abi Nahed R, Reynaud D, Lemaitre N, Lartigue S, Roelants C, Vaiman D, Benharouga M, Cochet C, Filhol O, Alfaidy N. | 04/17/2021 |
| Germline de novo variants in CSNK2B in Chinese patients with epilepsy. | Germline de novo variants in CSNK2B in Chinese patients with epilepsy.
Li J, Gao K, Cai S, Liu Y, Wang Y, Huang S, Zha J, Hu W, Yu S, Yang Z, Xie H, Yan H, Wang J, Wu Y, Jiang Y., Free PMC Article | 11/21/2020 |
| Tumor necrosis factor alpha-induced protein 1 as a novel tumor suppressor through selective downregulation of CSNK2B blocks nuclear factor-kappaB activation in hepatocellular carcinoma. | Tumor necrosis factor α-induced protein 1 as a novel tumor suppressor through selective downregulation of CSNK2B blocks nuclear factor-κB activation in hepatocellular carcinoma.
Xiao Y, Huang S, Qiu F, Ding X, Sun Y, Wei C, Hu X, Wei K, Long S, Xie L, Xun Y, Chen W, Zhang Z, Liu N, Xiang S., Free PMC Article | 10/3/2020 |
| The stability of CREB3/Luman is regulated by protein kinase CK2 phosphorylation. | The stability of CREB3/Luman is regulated by protein kinase CK2 phosphorylation.
Schmitt BM, Ampofo E, Stumpf H, Montenarh M, Götz C. | 09/12/2020 |
| The effects of LY294002 were observed also in CK2beta-downregulated cells, suggesting that reducing GSK3beta pS9 could be a strategy to control Snail1 levels in any situation where CK2beta is defective, as possibly occurring in cancer cells | Effects of CK2β subunit down-regulation on Akt signalling in HK-2 renal cells.
Alcaraz E, Vilardell J, Borgo C, Sarró E, Plana M, Marin O, Pinna LA, Bayascas JR, Meseguer A, Salvi M, Itarte E, Ruzzene M., Free PMC Article | 04/11/2020 |
| This and previous studies have found a total of 20 CSNK2A1 variants in 28 individuals with syndromic intellectual disability. The hotspot variant c.593A>G, p.(Lys198Arg) was found in eight of 28 patients. Meanwhile, only five CSNK2B variants were identified in five individuals with neurodevelopmental disorders. We reviewed the previous literature to verify the phenotypic spectrum of CSNK2A1- and CSNK2B-related syndromes | Identification of de novo CSNK2A1 and CSNK2B variants in cases of global developmental delay with seizures.
Nakashima M, Tohyama J, Nakagawa E, Watanabe Y, Siew CG, Kwong CS, Yamoto K, Hiraide T, Fukuda T, Kaname T, Nakabayashi K, Hata K, Ogata T, Saitsu H, Matsumoto N. | 03/16/2019 |
| Patients described are the first cases presenting a loss-of-function variant in the CSNK2B gene in the context of intellectual disability (ID), suggesting that CSNK2Bvariants can cause ID. | CSNK2B splice site mutations in patients cause intellectual disability with or without myoclonic epilepsy.
Poirier K, Hubert L, Viot G, Rio M, Billuart P, Besmond C, Bienvenu T. | 06/23/2018 |
| ALMS1, GLT8D1, and CSNK2B are schizophrenia risk genes. | Comprehensive integrative analyses identify GLT8D1 and CSNK2B as schizophrenia risk genes.
Yang CP, Li X, Wu Y, Shen Q, Zeng Y, Xiong Q, Wei M, Chen C, Liu J, Huo Y, Li K, Xue G, Yao YG, Zhang C, Li M, Chen Y, Luo XJ., Free PMC Article | 05/12/2018 |
| CK2 is required to mediate FXR SUMOylation. | A CK2-RNF4 interplay coordinates non-canonical SUMOylation and degradation of nuclear receptor FXR.
Bilodeau S, Caron V, Gagnon J, Kuftedjian A, Tremblay A., Free PMC Article | 04/7/2018 |
| We report interactions between CSNK-2beta and IGFBP-1 as well as mTOR and CSNK-2beta, providing strong evidence of a mechanistic link between mTOR and IGF-I signaling, two critical regulators of cell growth via CSNK-2. | Co-Localization of Insulin-Like Growth Factor Binding Protein-1, Casein Kinase-2β, and Mechanistic Target of Rapamycin in Human Hepatocellular Carcinoma Cells as Demonstrated by Dual Immunofluorescence and in Situ Proximity Ligation Assay.
Singal SS, Nygard K, Dhruv MR, Biggar K, Shehab MA, Li SS, Jansson T, Gupta MB., Free PMC Article | 01/13/2018 |
| The lack of intermediate species of CK2 alpha2beta2 in solution suggests that the holoenzyme is a strong/stable multimeric complex that does not spontaneously dissociate; a considerable amount of monomer, the active form of CK2, is present in low ionic strength solutions. Multimer assembly appears driven by electrostatic interactions between the CK2alpha P+1 loop and the CK2beta acidic loop. | Characterization of the oligomeric states of the CK2 α(2)β(2) holoenzyme in solution.
Lolli G, Naressi D, Sarno S, Battistutta R. | 07/29/2017 |
| These data support a role for casein kinase 2 in regulation of protein synthesis by downregulating stress granule formation through G3BP1. | Casein Kinase 2 Is Linked to Stress Granule Dynamics through Phosphorylation of the Stress Granule Nucleating Protein G3BP1.
Reineke LC, Tsai WC, Jain A, Kaelber JT, Jung SY, Lloyd RE., Free PMC Article | 07/1/2017 |
| Casein kinase 2 role in the proliferation of human osteosarcoma cells. | Inhibition of casein kinase 2 prevents growth of human osteosarcoma.
Takahashi K, Setoguchi T, Tsuru A, Saitoh Y, Nagano S, Ishidou Y, Maeda S, Furukawa T, Komiya S. | 03/25/2017 |
| Data suggest that cryptochromes mediate periodic binding of Ck2b (casein kinase 2beta) to Bmal1 (aryl hydrocarbon receptor nuclear translocator-like protein) and thus inhibit Bmal1-Ser90 phosphorylation by Ck2a (casein kinase 2alpha). [SYNOPSIS] | A New Role Discovered for a Well-Known Clock Protein.
Robinson R., Free PMC Article | 05/28/2016 |
| Data suggest that cryptochromes (Cry1 and Cry2) mediate periodic binding of Ck2b (casein kinase 2beta) to Bmal1 (aryl hydrocarbon receptor nuclear translocator-like protein) and thus inhibit Bmal1-Ser90 phosphorylation by Ck2a (casein kinase 2alpha). | CRY Drives Cyclic CK2-Mediated BMAL1 Phosphorylation to Control the Mammalian Circadian Clock.
Tamaru T, Hattori M, Honda K, Nakahata Y, Sassone-Corsi P, van der Horst GT, Ozawa T, Takamatsu K., Free PMC Article | 05/28/2016 |
| AMPKalpha signalling suppresses EMT and secretion of chemokines in renal tubular epithelia through interaction with CK2beta to attenuate renal injury. | AMPKα2 reduces renal epithelial transdifferentiation and inflammation after injury through interaction with CK2β.
Qiu S, Xiao Z, Piao C, Zhang J, Dong Y, Cui W, Liu X, Zhang Y, Du J. | 04/16/2016 |
| CK2 is widely expressed in follicular, Burkitt and diffuse large B-cell lymphomas and may have role in malignant B-cell growth. | Protein kinase CK2 is widely expressed in follicular, Burkitt and diffuse large B-cell lymphomas and propels malignant B-cell growth.
Pizzi M, Piazza F, Agostinelli C, Fuligni F, Benvenuti P, Mandato E, Casellato A, Rugge M, Semenzato G, Pileri SA., Free PMC Article | 01/23/2016 |
| we propose that Foxc2 is functionally maintained in the cytoplasm of normal epithelial cells by CK2alpha/alpha'-mediated phosphorylation at serine 124, which is dependent on proper targeting of the holoenzyme via the CK2b regulatory subunit. | Casein kinase 2 prevents mesenchymal transformation by maintaining Foxc2 in the cytoplasm.
Golden D, Cantley LG., Free PMC Article | 11/28/2015 |