| Muscle-resident mesenchymal progenitors sense and repair peripheral nerve injury via the GDNF-BDNF axis. | Muscle-resident mesenchymal progenitors sense and repair peripheral nerve injury via the GDNF-BDNF axis.
Yoo K, Jo YW, Yoo T, Hann SH, Park I, Kim YE, Kim YL, Rhee J, Song IW, Kim JH, Baek D, Kong YY., Free PMC Article | 10/1/2024 |
| Astrocytic GDNF ameliorates anesthesia and surgery-induced cognitive impairment by promoting hippocampal synaptic plasticity in aged mice. | Astrocytic GDNF ameliorates anesthesia and surgery-induced cognitive impairment by promoting hippocampal synaptic plasticity in aged mice.
Lin X, Ren P, Xue Z, Liu X, Cao Y, Li T, Miao H. | 10/1/2024 |
| Environmental enrichment accentuates glucose-induced feeding suppression and glial cell line-derived neurotrophic factor gene expression in the hypothalamus of mice. | Environmental enrichment accentuates glucose-induced feeding suppression and glial cell line-derived neurotrophic factor gene expression in the hypothalamus of mice.
Aldhshan MS, Mizuno TM. | 01/17/2024 |
| Functional role of glial-derived neurotrophic factor in a mixed allergen murine model of asthma. | Functional role of glial-derived neurotrophic factor in a mixed allergen murine model of asthma.
Drake LY, Wicher SA, Roos BB, Khalfaoui L, Nesbitt L, Fang YH, Pabelick CM, Prakash YS., | 01/3/2024 |
| Glial cell derived neurotrophic factor prevents western diet and palmitate-induced hepatocyte oxidative damage and death through SIRT3. | Glial cell derived neurotrophic factor prevents western diet and palmitate-induced hepatocyte oxidative damage and death through SIRT3.
Mwangi SM, Li G, Balasubramaniam A, Merlin D, Dawson PA, Jang YC, Hart CM, Czaja MJ, Srinivasan S., Free PMC Article | 10/15/2022 |
| Overexpression of Brain- and Glial Cell Line-Derived Neurotrophic Factors Is Neuroprotective in an Animal Model of Acute Hypobaric Hypoxia. | Overexpression of Brain- and Glial Cell Line-Derived Neurotrophic Factors Is Neuroprotective in an Animal Model of Acute Hypobaric Hypoxia.
Gavrish MS, Urazov MD, Mishchenko TA, Turubanova VD, Epifanova EA, Krut' VG, Babaev AA, Vedunova MV, Mitroshina EV., Free PMC Article | 10/1/2022 |
| Astrocytic SARM1 promotes neuroinflammation and axonal demyelination in experimental autoimmune encephalomyelitis through inhibiting GDNF signaling. | Astrocytic SARM1 promotes neuroinflammation and axonal demyelination in experimental autoimmune encephalomyelitis through inhibiting GDNF signaling.
Jin L, Zhang J, Hua X, Xu X, Li J, Wang J, Wang M, Liu H, Qiu H, Chen M, Zhang X, Wang Y, Huang Z., Free PMC Article | 09/24/2022 |
| Bimodal regulation of axonal transport by the GDNF-RET signalling axis in healthy and diseased motor neurons. | Bimodal regulation of axonal transport by the GDNF-RET signalling axis in healthy and diseased motor neurons.
Rhymes ER, Tosolini AP, Fellows AD, Mahy W, McDonald NQ, Schiavo G., Free PMC Article | 07/16/2022 |
| Tumoral Neuroligin 1 Promotes Cancer-Nerve Interactions and Synergizes with the Glial Cell Line-Derived Neurotrophic Factor. | Tumoral Neuroligin 1 Promotes Cancer-Nerve Interactions and Synergizes with the Glial Cell Line-Derived Neurotrophic Factor.
Bizzozero L, Pergolizzi M, Pascal D, Maldi E, Villari G, Erriquez J, Volante M, Serini G, Marchiò C, Bussolino F, Arese M., Free PMC Article | 02/26/2022 |
| Boosting effect of testosterone on GDNF expression in Sertoli cell line (TM4); comparison between TM3 cells-produced and exogenous testosterone. | Boosting effect of testosterone on GDNF expression in Sertoli cell line (TM4); comparison between TM3 cells-produced and exogenous testosterone.
Zaker H, Razi M, Mahmoudian A, Soltanalinejad F. | 01/15/2022 |
| TNF-alpha inhibits GDNF levels in Sertoli cells, through a NF-kappaB-dependent, HES1-dependent mechanism. | TNF-α inhibits GDNF levels in Sertoli cells, through a NF-κB-dependent, HES1-dependent mechanism.
Di Persio S, Starace D, Capponi C, Saracino R, Fera S, Filippini A, Vicini E. | 12/4/2021 |
| Postnatal prolongation of mammalian nephrogenesis by excess fetal GDNF. | Postnatal prolongation of mammalian nephrogenesis by excess fetal GDNF.
Li H, Kurtzeborn K, Kupari J, Gui Y, Siefker E, Lu B, Mätlik K, Olfat S, Montaño-Rodríguez AR, Huh SH, Costantini F, Andressoo JO, Kuure S., Free PMC Article | 10/9/2021 |
| Renal pathology in a mouse model of severe Spinal Muscular Atrophy is associated with downregulation of Glial Cell-Line Derived Neurotrophic Factor (GDNF). | Renal pathology in a mouse model of severe Spinal Muscular Atrophy is associated with downregulation of Glial Cell-Line Derived Neurotrophic Factor (GDNF).
Allardyce H, Kuhn D, Hernandez-Gerez E, Hensel N, Huang YT, Faller K, Gillingwater TH, Quondamatteo F, Claus P, Parson SH. | 08/21/2021 |
| GDNF drives rapid tubule morphogenesis in a novel 3D in vitro model for ADPKD. | GDNF drives rapid tubule morphogenesis in a novel 3D in vitro model for ADPKD.
Dixon EE, Maxim DS, Halperin Kuhns VL, Lane-Harris AC, Outeda P, Ewald AJ, Watnick TJ, Welling PA, Woodward OM., Free PMC Article | 08/7/2021 |
| Role of Glial Cell Line-Derived Neurotrophic Factor in the Maintenance of Adult Mesencephalic Catecholaminergic Neurons. | Role of Glial Cell Line-Derived Neurotrophic Factor in the Maintenance of Adult Mesencephalic Catecholaminergic Neurons.
Enterría-Morales D, López-López I, López-Barneo J, d'Anglemont de Tassigny X. | 05/8/2021 |
| Intestinal Epithelial Barrier Maturation by Enteric Glial Cells Is GDNF-Dependent. | Intestinal Epithelial Barrier Maturation by Enteric Glial Cells Is GDNF-Dependent.
Meir M, Kannapin F, Diefenbacher M, Ghoreishi Y, Kollmann C, Flemming S, Germer CT, Waschke J, Leven P, Schneider R, Wehner S, Burkard N, Schlegel N., Free PMC Article | 04/24/2021 |
| Muscle stem cell renewal suppressed by Gas1 can be reversed by GDNF in mice. | Muscle stem cell renewal suppressed by Gas1 can be reversed by GDNF in mice.
Li L, Rozo M, Yue S, Zheng X, J Tan F, Lepper C, Fan CM., Free PMC Article | 01/2/2021 |
| Acute stress disrupts intestinal homeostasis via GDNF-RET. | Acute stress disrupts intestinal homeostasis via GDNF-RET.
Lin L, Feng B, Zhou R, Liu Y, Li L, Wang K, Yu Y, Liu C, Long X, Gu X, Li B, Wang X, Yang X, Cong Y, Zuo X, Li Y., Free PMC Article | 10/31/2020 |
| GDNF and GFRalpha1 Are Required for Proper Integration of Adult-Born Hippocampal Neurons. | GDNF and GFRα1 Are Required for Proper Integration of Adult-Born Hippocampal Neurons.
Bonafina A, Trinchero MF, Ríos AS, Bekinschtein P, Schinder AF, Paratcha G, Ledda F. | 10/3/2020 |
| Development of the urogenital system is regulated via the 3'UTR of GDNF. | Development of the urogenital system is regulated via the 3'UTR of GDNF.
Li H, Jakobson M, Ola R, Gui Y, Kumar A, Sipilä P, Sariola H, Kuure S, Andressoo JO., Free PMC Article | 10/3/2020 |
| Cinnamon and its Metabolite Protect the Nigrostriatum in a Mouse Model of Parkinson's Disease Via Astrocytic GDNF. | Cinnamon and its Metabolite Protect the Nigrostriatum in a Mouse Model of Parkinson's Disease Via Astrocytic GDNF.
Patel D, Jana A, Roy A, Pahan K., Free PMC Article | 09/19/2020 |
| GDNF attenuates inflammation-induced impairment of Impaired intestinal epithelial barrier function caused by the loss of DSG2 through p38 MAPK-dependent phosphorylation of cytokeratin. | Neurotrophic factor GDNF regulates intestinal barrier function in inflammatory bowel disease.
Meir M, Burkard N, Ungewiß H, Diefenbacher M, Flemming S, Kannapin F, Germer CT, Schweinlin M, Metzger M, Waschke J, Schlegel N., Free PMC Article | 05/23/2020 |
| Increased GDNF/GFRalpha1 signaling to sensory neurons from ischemia/reperfusion-affected muscle directly modulated nociceptive-like behaviors and increased exercise-mediated reflexes and group III/IV muscle afferent sensitization. Muscle GDNF signaling to neurons may play an important dual role in nociception and sympathetic reflexes and could provide a therapeutic target for treating complications from ischemic injuries. | A dual role for peripheral GDNF signaling in nociception and cardiovascular reflexes in the mouse.
Queme LF, Weyler AA, Cohen ER, Hudgins RC, Jankowski MP., Free PMC Article | 05/9/2020 |
| A modest elevation of endogenous GDNF levels improves motor function but does not induce adverse behavioral outcomes. | Two-fold elevation of endogenous GDNF levels in mice improves motor coordination without causing side-effects.
Mätlik K, Võikar V, Vilenius C, Kulesskaya N, Andressoo JO., Free PMC Article | 10/19/2019 |
| Study shows that MiR-33-5p, through its inverse regulation on glial cell-derived neurotrophic factor gene, modulates anesthesia-induced neural apoptosis in dorsal root ganglion cells. | Downregulation of MicroRNA-33-5p Protected Bupivacaine-Induced Apoptosis in Murine Dorsal Root Ganglion Neurons Through GDNF.
Zhang H, Wang K. | 05/25/2019 |