Bulk and single-cell transcriptome profiling identify potential cellular targets of the long noncoding RNA Gas5 in renal fibrosis. | Bulk and single-cell transcriptome profiling identify potential cellular targets of the long noncoding RNA Gas5 in renal fibrosis. Zhang X, Hu S, Xiang X, Li Z, Chen Z, Xia C, He Q, Jin J, Chen H. | 06/17/2024 |
Exosomal lncRNA GAS5 promotes M1 macrophage polarization in allergic rhinitis via restraining mTORC1/ULK1/ATG13-mediated autophagy and subsequently activating NF-small ka, CyrillicB signaling. | Exosomal lncRNA GAS5 promotes M1 macrophage polarization in allergic rhinitis via restraining mTORC1/ULK1/ATG13-mediated autophagy and subsequently activating NF-кB signaling. Zhu X, Sun Y, Yu Q, Wang X, Wang Y, Zhao Y. | 07/26/2023 |
LncRNA GAS5 suppresses TGF-beta1-induced transformation of pulmonary pericytes into myofibroblasts by recruiting KDM5B and promoting H3K4me2/3 demethylation of the PDGFRalpha/beta promoter. | LncRNA GAS5 suppresses TGF-β1-induced transformation of pulmonary pericytes into myofibroblasts by recruiting KDM5B and promoting H3K4me2/3 demethylation of the PDGFRα/β promoter. Wang Y, Chen D, Xie H, Zhou S, Jia M, He X, Guo F, Lai Y, Tang XX., Free PMC Article | 03/22/2023 |
LncRNA GAS5 suppresses inflammatory responses by inhibiting HMGB1 release via miR-155-5p/SIRT1 axis in sepsis. | LncRNA GAS5 suppresses inflammatory responses by inhibiting HMGB1 release via miR-155-5p/SIRT1 axis in sepsis. Zeng Z, Lan Y, Chen Y, Zuo F, Gong Y, Luo G, Peng Y, Yuan Z. | 02/14/2023 |
LncRNA GAS5 Knockdown Mitigates Hepatic Lipid Accumulation via Regulating MiR-26a-5p/PDE4B to Activate cAMP/CREB Pathway. | LncRNA GAS5 Knockdown Mitigates Hepatic Lipid Accumulation via Regulating MiR-26a-5p/PDE4B to Activate cAMP/CREB Pathway. Xu S, Wang Y, Li Z, Hua Q, Jiang M, Fan X., Free PMC Article | 09/3/2022 |
Gas5 inhibition promotes the axon regeneration in the adult mammalian nervous system. | Gas5 inhibition promotes the axon regeneration in the adult mammalian nervous system. Han X, Xu J, Chen Z, Li P, Zhao L, Tao J, Shen Y, Zhu S, Yu B, Zhu J, Cao Q, Zhou S. | 08/13/2022 |
Long noncoding RNA GAS5 attenuates cigarette smoke-induced airway remodeling by regulating miR-217-5p/PTEN axis. | Long noncoding RNA GAS5 attenuates cigarette smoke-induced airway remodeling by regulating miR-217-5p/PTEN axis. Du Y, Ding Y, Shi T, He W, Feng J, Mei Z, Chen X, Feng X, Zhang X, Jie Z., Free PMC Article | 07/30/2022 |
Long non-coding RNA GAS5 contributes to the progression of nonalcoholic fatty liver disease by targeting the microRNA-29a-3p/NOTCH2 axis. | Long non-coding RNA GAS5 contributes to the progression of nonalcoholic fatty liver disease by targeting the microRNA-29a-3p/NOTCH2 axis. Cui J, Wang Y, Xue H., Free PMC Article | 07/30/2022 |
LncRNA Gas5 regulates Fn1 deposition via Creb5 in renal fibrosis. | LncRNA Gas5 regulates Fn1 deposition via Creb5 in renal fibrosis. Su H, Xie J, Wen L, Wang S, Chen S, Li J, Qi C, Zhang Q, He X, Zheng L, Wang L. | 03/12/2022 |
LncRNA GAS5/miR-137 Is a Hypoxia-Responsive Axis Involved in Cardiac Arrest and Cardiopulmonary Cerebral Resuscitation. | LncRNA GAS5/miR-137 Is a Hypoxia-Responsive Axis Involved in Cardiac Arrest and Cardiopulmonary Cerebral Resuscitation. Jing W, Tuxiu X, Xiaobing L, Guijun J, Lulu K, Jie J, Lu Y, Liying Z, Xiaoxing X, Jingjun L., Free PMC Article | 02/26/2022 |
Longchain noncoding RNA GAS5 promotes cell autophagy by modulating the miR181c5p/ATG5 and miR1192/ATG12 axes. | Long‑chain non‑coding RNA GAS5 promotes cell autophagy by modulating the miR‑181c‑5p/ATG5 and miR‑1192/ATG12 axes. Xu T, Xu X, Chu Y, Jiang D, Xu G., Free PMC Article | 02/12/2022 |
Long-chain noncoding RNA-GAS5/hsa-miR-138-5p attenuates high glucose-induced cardiomyocyte damage by targeting CYP11B2. | Long-chain noncoding RNA-GAS5/hsa-miR-138-5p attenuates high glucose-induced cardiomyocyte damage by targeting CYP11B2. Zhuo X, Bai K, Wang Y, Liu P, Xi W, She J, Liu J., Free PMC Article | 02/5/2022 |
Acinetobacter baumannii up-regulates LncRNA-GAS5 and promotes the degradation of STX17 by blocking the activation of YY1. | Acinetobacter baumannii up-regulates LncRNA-GAS5 and promotes the degradation of STX17 by blocking the activation of YY1. An Z, Ding W., Free PMC Article | 01/29/2022 |
The SRSF4-GAS5-Glucocorticoid Receptor Axis Regulates Ventricular Hypertrophy. | The SRSF4-GAS5-Glucocorticoid Receptor Axis Regulates Ventricular Hypertrophy. Larrasa-Alonso J, Villalba-Orero M, Martí-Gómez C, Ortiz-Sánchez P, López-Olañeta MM, Rey-Martín MA, Sánchez-Cabo F, McNicoll F, Müller-McNicoll M, García-Pavía P, Lara-Pezzi E., Free PMC Article | 01/15/2022 |
The long noncoding RNA GAS5 potentiates neuronal injury in Parkinson's disease by binding to microRNA-150 to regulate Fosl1 expression. | The long noncoding RNA GAS5 potentiates neuronal injury in Parkinson's disease by binding to microRNA-150 to regulate Fosl1 expression. Ma J, Sun W, Chen S, Wang Z, Zheng J, Shi X, Li M, Li D, Gu Q. | 01/1/2022 |
Identification and characterization of key long non-coding RNAs in the mouse cochlea. | Identification and characterization of key long non-coding RNAs in the mouse cochlea. Koffler-Brill T, Taiber S, Anaya A, Bordeynik-Cohen M, Rosen E, Kolla L, Messika-Gold N, Elkon R, Kelley MW, Ulitsky I, Avraham KB., Free PMC Article | 01/1/2022 |
Long non-coding RNA GAS5 aggravates myocardial depression in mice with sepsis via the microRNA-449b/HMGB1 axis and the NF-kappaB signaling pathway. | Long non-coding RNA GAS5 aggravates myocardial depression in mice with sepsis via the microRNA-449b/HMGB1 axis and the NF-κB signaling pathway. Gao H, Ma H, Gao M, Chen A, Zha S, Yan J., Free PMC Article | 12/25/2021 |
LncRNA GAS5 inhibits NLRP3 inflammasome activation-mediated pyroptosis in diabetic cardiomyopathy by targeting miR-34b-3p/AHR. | LncRNA GAS5 inhibits NLRP3 inflammasome activation-mediated pyroptosis in diabetic cardiomyopathy by targeting miR-34b-3p/AHR. Xu Y, Fang H, Xu Q, Xu C, Yang L, Huang C., Free PMC Article | 12/4/2021 |
LncRNA GAS5 inhibits miR-579-3p to activate SIRT1/PGC-1alpha/Nrf2 signaling pathway to reduce cell pyroptosis in sepsis-associated renal injury. | LncRNA GAS5 inhibits miR-579-3p to activate SIRT1/PGC-1α/Nrf2 signaling pathway to reduce cell pyroptosis in sepsis-associated renal injury. Ling H, Li Q, Duan ZP, Wang YJ, Hu BQ, Dai XG. | 09/11/2021 |
Silencing of Long Non-coding RNA GAS5 Suppresses Neuron Cell Apoptosis and Nerve Injury in Ischemic Stroke Through Inhibiting DNMT3B-Dependent MAP4K4 Methylation. | Silencing of Long Non-coding RNA GAS5 Suppresses Neuron Cell Apoptosis and Nerve Injury in Ischemic Stroke Through Inhibiting DNMT3B-Dependent MAP4K4 Methylation. Deng Y, Chen D, Gao F, Lv H, Zhang G, Sun X, Liu L, Mo D, Ma N, Song L, Huo X, Yan T, Zhang J, Luo Y, Miao Z. | 07/24/2021 |
Long noncoding RNA GAS5 promotes microglial inflammatory response in Parkinson's disease by regulating NLRP3 pathway through sponging miR-223-3p. | Long noncoding RNA GAS5 promotes microglial inflammatory response in Parkinson's disease by regulating NLRP3 pathway through sponging miR-223-3p. Xu W, Zhang L, Geng Y, Liu Y, Zhang N. | 05/1/2021 |
Long Noncoding RNA GAS5 Regulates Macrophage Polarization and Diabetic Wound Healing. | Long Noncoding RNA GAS5 Regulates Macrophage Polarization and Diabetic Wound Healing. Hu J, Zhang L, Liechty C, Zgheib C, Hodges MM, Liechty KW, Xu J., Free PMC Article | 03/13/2021 |
Exaggerated renal fibrosis in lncRNA Gas5-deficient mice after unilateral ureteric obstruction. | Exaggerated renal fibrosis in lncRNA Gas5-deficient mice after unilateral ureteric obstruction. Guo Y, Li G, Gao L, Cheng X, Wang L, Qin Y, Zhang D. | 01/2/2021 |
LncRNA GAS5 inhibits Th17 differentiation and alleviates immune thrombocytopenia via promoting the ubiquitination of STAT3. | LncRNA GAS5 inhibits Th17 differentiation and alleviates immune thrombocytopenia via promoting the ubiquitination of STAT3. Li J, Tian J, Lu J, Wang Z, Ling J, Wu X, Yang F, Xia Y. | 11/28/2020 |
LncRNA GAS5 attenuates fibroblast activation through inhibiting Smad3 signaling. | LncRNA GAS5 attenuates fibroblast activation through inhibiting Smad3 signaling. Tang R, Wang YC, Mei X, Shi N, Sun C, Ran R, Zhang G, Li W, Staveley-O'Carroll KF, Li G, Chen SY., Free PMC Article | 10/24/2020 |