G-CSF reshapes the cytosolic PCNA scaffold and modulates glycolysis in neutrophils. | G-CSF reshapes the cytosolic PCNA scaffold and modulates glycolysis in neutrophils. Aymonnier K, Bosetta E, Leborgne NGF, Ullmer A, Le Gall M, De Chiara A, Salnot V, Many S, Scapini P, Wicks I, Chatfield S, Martin KR, Witko-Sarsat V. | 01/26/2024 |
Serum cytokines MCP-1 and GCS-F as potential biomarkers in pediatric inflammatory bowel disease. | Serum cytokines MCP-1 and GCS-F as potential biomarkers in pediatric inflammatory bowel disease. Ott A, Tutdibi E, Goedicke-Fritz S, Schöpe J, Zemlin M, Nourkami-Tutdibi N., Free PMC Article | 11/8/2023 |
Tumor-derived GCSF Alters Tumor and Systemic Immune System Cell Subset Composition and Signaling. | Tumor-derived GCSF Alters Tumor and Systemic Immune System Cell Subset Composition and Signaling. Matos I, Barvalia M, Chehal MK, Robertson AG, Kulic I, Silva JAFD, Ranganathan A, Short A, Huang YH, Long E, Priatel JJ, Dhanji S, Nelson BH, Krebs DL, Harder KW., Free PMC Article | 08/9/2023 |
p140Cap inhibits beta-Catenin in the breast cancer stem cell compartment instructing a protective anti-tumor immune response. | p140Cap inhibits β-Catenin in the breast cancer stem cell compartment instructing a protective anti-tumor immune response. Salemme V, Vedelago M, Sarcinella A, Moietta F, Piccolantonio A, Moiso E, Centonze G, Manco M, Guala A, Lamolinara A, Angelini C, Morellato A, Natalini D, Calogero R, Incarnato D, Oliviero S, Conti L, Iezzi M, Tosoni D, Bertalot G, Freddi S, Tucci FA, De Sanctis F, Frusteri C, Ugel S, Bronte V, Cavallo F, Provero P, Gai M, Taverna D, Turco E, Pece S, Defilippi P., Free PMC Article | 06/2/2023 |
Elevated G-CSF, IL8, and HGF in patients with definite Meniere's disease may indicate the role of NET formation in triggering autoimmunity and autoinflammation. | Elevated G-CSF, IL8, and HGF in patients with definite Meniere's disease may indicate the role of NET formation in triggering autoimmunity and autoinflammation. Zou J, Zhao Z, Song X, Zhang G, Li H, Zhang Q, Pyykkö I., Free PMC Article | 10/8/2022 |
G-CSF promotes the viability and angiogenesis of injured liver via direct effects on the liver cells. | G-CSF promotes the viability and angiogenesis of injured liver via direct effects on the liver cells. Liu Z, Zhang G, Chen J, Tong J, Wang H, Chen J, Yang D, Hu J., Free PMC Article | 09/17/2022 |
G-CSF as a potential early biomarker for diagnosis of bloodstream infection. | G-CSF as a potential early biomarker for diagnosis of bloodstream infection. Li H, Wang Z, Li X., Free PMC Article | 03/12/2022 |
Identification of differentially expressed genes and signaling pathways in human conjunctiva and reproductive tract infected with Chlamydia trachomatis. | Identification of differentially expressed genes and signaling pathways in human conjunctiva and reproductive tract infected with Chlamydia trachomatis. Zhu GD, Cao XJ, Li YP, Li JX, Leng ZJ, Xie LM, Guo XG., Free PMC Article | 02/5/2022 |
Plasma concentrations of granulocyte colony-stimulating factor (G-CSF) in patients with substance use disorders and comorbid major depressive disorder. | Plasma concentrations of granulocyte colony-stimulating factor (G-CSF) in patients with substance use disorders and comorbid major depressive disorder. Galván ST, Flores-López M, Romero-Sanchiz P, Requena-Ocaña N, Porras-Perales O, Nogueira-Arjona R, Mayoral F, Araos P, Serrano A, Muga R, Pavón FJ, García-Marchena N, de Fonseca FR., Free PMC Article | 11/6/2021 |
M2 macrophage-derived G-CSF promotes trophoblasts EMT, invasion and migration via activating PI3K/Akt/Erk1/2 pathway to mediate normal pregnancy. | M2 macrophage-derived G-CSF promotes trophoblasts EMT, invasion and migration via activating PI3K/Akt/Erk1/2 pathway to mediate normal pregnancy. Ding J, Yang C, Zhang Y, Wang J, Zhang S, Guo D, Yin T, Yang J., Free PMC Article | 09/25/2021 |
Colony-stimulating factor 3 signaling in colon and rectal cancers: Immune response and CMS classification in TCGA data. | Colony-stimulating factor 3 signaling in colon and rectal cancers: Immune response and CMS classification in TCGA data. Saunders AS, Bender DE, Ray AL, Wu X, Morris KT., Free PMC Article | 08/28/2021 |
Cancer-associated adipocyte-derived G-CSF promotes breast cancer malignancy via Stat3 signaling. | Cancer-associated adipocyte-derived G-CSF promotes breast cancer malignancy via Stat3 signaling. Liu L, Wu Y, Zhang C, Zhou C, Li Y, Zeng Y, Zhang C, Li R, Luo D, Wang L, Zhang L, Tu S, Deng H, Luo S, Chen YG, Xiong X, Yan X., Free PMC Article | 08/28/2021 |
Targeting IL-17A/glucocorticoid synergy to CSF3 expression in neutrophilic airway diseases. | Targeting IL-17A/glucocorticoid synergy to CSF3 expression in neutrophilic airway diseases. Ouyang S, Liu C, Xiao J, Chen X, Lui AC, Li X., Free PMC Article | 06/26/2021 |
Human Decidual Stromal Cells in Early Pregnancy Induce Functional Re-Programming of Monocyte-Derived Dendritic Cells via Crosstalk Between G-CSF and IL-1beta. | Human Decidual Stromal Cells in Early Pregnancy Induce Functional Re-Programming of Monocyte-Derived Dendritic Cells via Crosstalk Between G-CSF and IL-1β. Shao Q, Liu X, Huang Y, Chen X, Wang H., Free PMC Article | 06/19/2021 |
Investigating apoptotic, inflammatory, and growth markers in poor responders undergoing natural in vitro fertilization cycles: a pilot study. | Investigating apoptotic, inflammatory, and growth markers in poor responders undergoing natural in vitro fertilization cycles: a pilot study. Sfakianoudis K, Tsioulou P, Maziotis E, Grigoriadis S, Glava A, Nitsos N, Giannelou P, Makrakis E, Pantou A, Rapani A, Koutsilieris M, Mastorakos G, Pantos K, Simopoulou M. | 04/24/2021 |
A paracrine interaction between granulosa cells and leukocytes in the preovulatory follicle causes the increase in follicular G-CSF levels. | A paracrine interaction between granulosa cells and leukocytes in the preovulatory follicle causes the increase in follicular G-CSF levels. Noël L, Fransolet M, Jacobs N, Foidart JM, Nisolle M, Munaut C., Free PMC Article | 12/5/2020 |
This review summarizes the molecular regulatory mechanisms of neutrophil granulocytic differentiation and innate immunity development, dissects the biology of GCSF in myeloid expansion, highlights the shortcomings of GCSF in netropenia treatment. | Strategies to generate functionally normal neutrophils to reduce infection and infection-related mortality in cancer chemotherapy. Abdel-Azim H, Sun W, Wu L., Free PMC Article | 08/1/2020 |
ata demonstrate that kidney injury induces renal G-CSF expression and modulates granulopoiesis. They delineate differential G-CSF regulation in renal epithelium and endothelium. Altered granulopoiesis may contribute to the systemic impact of kidney injury. | Kidney injury enhances renal G-CSF expression and modulates granulopoiesis and human neutrophil CD177 in vivo. Volkmann J, Schmitz J, Nordlohne J, Dong L, Helmke A, Sen P, Immenschuh S, Bernhardt WM, Gwinner W, Bräsen JH, Schmitt R, Haller H, von Vietinghoff S., Free PMC Article | 07/25/2020 |
CXCL1 and CSF3 levels are controlled by MAFF in myometrial cells. | Regulation of CXCL1 chemokine and CSF3 cytokine levels in myometrial cells by the MAFF transcription factor. Saliba J, Coutaud B, Solovieva V, Lu F, Blank V., Free PMC Article | 07/18/2020 |
our results show that the in vivo application of G-CSF can modulate NK subpopulations, leading to an increased ratio of T and NK cells and decreased ratio of CD56(dim) and CD56(bri) NK cells as well as decreased NK1 populations in both peripheral blood and bone marrow. | Effect of the in vivo application of granulocyte colony-stimulating factor on NK cells in bone marrow and peripheral blood. Yu XX, Han TT, Xu LL, Chang YJ, Huang XJ, Zhao XY., Free PMC Article | 11/30/2019 |
The authors were able to prove that nutrients and oxygen deprivation activated non-malignant stromal fibroblasts, which in turn established with tumor cells a paracrine loop mediated by Interleukine-6 (IL-6), Activin-A and Granulocyte colony-stimulating factor (G-CSF), that drove subsequent tumor formation and cellular dedifferentiation. | Stroma-derived IL-6, G-CSF and Activin-A mediated dedifferentiation of lung carcinoma cells into cancer stem cells. Rodrigues CFD, Serrano E, Patrício MI, Val MM, Albuquerque P, Fonseca J, Gomes CMF, Abrunhosa AJ, Paiva A, Carvalho L, Botelho MF, Almeida L, Carreira IM, Alpoim MC., Free PMC Article | 10/26/2019 |
There are significant changes in levels of G-CSF between patients with and without severe bacterial infections, which could improve diagnostic accuracy in patients with severe bacterial infections. | Inflammatory Cytokine and Chemokine Patterns in Paediatric Patients with Suspected Serious Bacterial Infection. Rautiainen L, Pavare J, Grope I, Tretjakovs P, Gardovska D., Free PMC Article | 08/3/2019 |
G-CSF and IL-6 concentrations may be predictive of the onset of neonatal Leukemoid reaction. | Neonatal Leukemoid Reaction with Fetal Inflammatory Response Syndrome Is Associated with Elevated Serum Granulocyte Colony Stimulating Factor and Interleukin-6. Nakamura T, Hatanaka D, Kusakari M, Kashima K, Takizawa Y, Takahashi H, Yoshioka T, Takahashi N, Kamohara T. | 08/18/2018 |
we described the construction and characterization of three G-CSF dimeric proteins generated using different linker peptides. GCSF-Lalpha had the best performance in terms of purity and in vitro activity | Construction, Purification, and Characterization of a Homodimeric Granulocyte Colony-Stimulating Factor. Mickiene G, Dalgediene I, Dapkunas Z, Zvirblis G, Pesliakas H, Kaupinis A, Valius M, Mistiniene E, Pleckaityte M. | 07/14/2018 |
this study shows that cortisol inhibits CSF3 via DNA methylation and inhibits invasion in first-trimester trophoblast cells | Cortisol inhibits CSF2 and CSF3 via DNA methylation and inhibits invasion in first-trimester trophoblast cells. Smith A, Witte E, McGee D, Knott J, Narang K, Racicot K., Free PMC Article | 05/26/2018 |