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    Fgf6 fibroblast growth factor 6 [ Mus musculus (house mouse) ]

    Gene ID: 14177, updated on 12-May-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Skeletal muscle-targeted delivery of Fgf6 protects mice from diet-induced obesity and insulin resistance.

    Skeletal muscle-targeted delivery of Fgf6 protects mice from diet-induced obesity and insulin resistance.
    Xu B, Liu C, Zhang H, Zhang R, Tang M, Huang Y, Jin L, Xu L, Hu C, Jia W., Free PMC Article

    03/19/2022
    Fibroblast growth factor 6 regulates sizing of the muscle stem cell pool.

    Fibroblast growth factor 6 regulates sizing of the muscle stem cell pool.
    Zofkie W, Southard SM, Braun T, Lepper C., Free PMC Article

    03/5/2022
    FGF6 and FGF9 are potent inducers of UCP1 expression in adipocytes and preadipocytes.

    FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis.
    Shamsi F, Xue R, Huang TL, Lundh M, Liu Y, Leiria LO, Lynes MD, Kempf E, Wang CH, Sugimoto S, Nigro P, Landgraf K, Schulz T, Li Y, Emanuelli B, Kothakota S, Williams LT, Jessen N, Pedersen SB, Böttcher Y, Blüher M, Körner A, Goodyear LJ, Mohammadi M, Kahn CR, Tseng YH., Free PMC Article

    08/1/2020
    A crucial and unexpected role for FGF6 in muscle integrity and muscle protection against mechanical stress.

    Eccentric stimulation reveals an involvement of FGF6 in muscle resistance to mechanical stress.
    Laziz I, Ferry A, Armand AS, Gallien CL, Gaspera BD, Charbonnier F, Chanoine C.

    11/12/2011
    Rescue experiments supported the idea of a specific relationship between FGF6 and Spry 2, both being known for their particular involvement in myogenesis.

    Sprouty gene expression is regulated by nerve and FGF6 during regeneration of mouse muscles.
    Laziz I, Armand AS, Pariset C, Lecolle S, Della Gaspera B, Charbonnier F, Chanoine C.

    01/21/2010
    a role for FGF6 in the maintenance of a reserve pool of progenitor cells in the skeletal muscle

    FGF6 mediated expansion of a resident subset of cells with SP phenotype in the C2C12 myogenic line.
    Israeli D, Benchaouir R, Ziaei S, Rameau P, Gruszczynski C, Peltekian E, Danos O, Garcia L.

    01/21/2010
    Involvement of FGF6 in myogenesis. Review.

    FGF6 in myogenesis.
    Armand AS, Laziz I, Chanoine C.

    01/21/2010
    In the absence of FGF6, the mechanisms leading to myofibre hypertrophy were mediated specifically by an IGF-II/IGF2R signalling pathway distinct from the classic mechanism involving IGF-I and IGF1R.

    IGF-II is up-regulated and myofibres are hypertrophied in regenerating soleus of mice lacking FGF6.
    Armand AS, Lécolle S, Launay T, Pariset C, Fiore F, Della Gaspera B, Birnbaum D, Chanoine C, Charbonnier F.

    01/21/2010
    At high doses, FGF6 stimulates the proliferation of the myogenic stem cells, whereas at lower doses it regulates both muscle differentiation and muscle phenotype via a calcineurin-signaling pathway.

    FGF6 regulates muscle differentiation through a calcineurin-dependent pathway in regenerating soleus of adult mice.
    Armand AS, Pariset C, Laziz I, Launay T, Fiore F, Della Gaspera B, Birnbaum D, Charbonnier F, Chanoine C.

    01/21/2010
    We show that the combined loss of FGF2 and FGF6 leads to severe dystrophic changes in the musculature.

    Reduced mobility of fibroblast growth factor (FGF)-deficient myoblasts might contribute to dystrophic changes in the musculature of FGF2/FGF6/mdx triple-mutant mice.
    Neuhaus P, Oustanina S, Loch T, Krüger M, Bober E, Dono R, Zeller R, Braun T., Free PMC Article

    01/21/2010
    might be involved in the changes of secretory granule content of acinar cells in the sublingual gland during the late gestational and early neonatal stages

    Localization of FGF-6 and FGFR-4 during prenatal and early postnatal development of the mouse sublingual gland.
    Uehara T.

    01/21/2010
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