| FGF13 enhances the function of TRPV1 by stabilizing microtubules and regulates acute and chronic itch. | FGF13 enhances the function of TRPV1 by stabilizing microtubules and regulates acute and chronic itch.
Dong ZS, Zhang XR, Xue DZ, Liu JH, Yi F, Zhang YY, Xian FY, Qiao RY, Liu BY, Zhang HL, Wang C. | 07/3/2024 |
| Enhanced sodium channel inactivation by temperature and FHF2 deficiency blocks heat nociception. | Enhanced sodium channel inactivation by temperature and FHF2 deficiency blocks heat nociception.
Marra C, Hartke TV, Ringkamp M, Goldfarb M., Free PMC Article | 05/18/2023 |
| Fibroblast growth factor 13 is involved in the pathogenesis of temporal lobe epilepsy. | Fibroblast growth factor 13 is involved in the pathogenesis of temporal lobe epilepsy.
Shen KF, Yue J, Wu ZF, Wu KF, Zhu G, Yang XL, Wang ZK, Wang J, Liu SY, Yang H, Zhang CQ. | 12/10/2022 |
| 5'-UTR SNP of FGF13 causes translational defect and intellectual disability. | 5'-UTR SNP of FGF13 causes translational defect and intellectual disability.
Pan X, Zhao J, Zhou Z, Chen J, Yang Z, Wu Y, Bai M, Jiao Y, Yang Y, Hu X, Cheng T, Lu Q, Wang B, Li CL, Lu YJ, Diao L, Zhong YQ, Pan J, Zhu J, Xiao HS, Qiu ZL, Li J, Wang Z, Hui J, Bao L, Zhang X., Free PMC Article | 09/25/2021 |
| Ionic Mechanisms of Impulse Propagation Failure in the FHF2-Deficient Heart. | Ionic Mechanisms of Impulse Propagation Failure in the FHF2-Deficient Heart.
Park DS, Shekhar A, Santucci J 3rd, Redel-Traub G, Solinas S, Mintz S, Lin X, Chang EW, Narke D, Xia Y, Goldfarb M, Fishman GI., Free PMC Article | 05/29/2021 |
| FGF13 Is Required for Histamine-Induced Itch Sensation by Interaction with NaV1.7. | FGF13 Is Required for Histamine-Induced Itch Sensation by Interaction with Na(V)1.7.
Dong F, Shi H, Yang L, Xue H, Wei M, Zhong YQ, Bao L, Zhang X., Free PMC Article | 03/6/2021 |
| E2F1 Drives Breast Cancer Metastasis by Regulating the Target Gene FGF13 and Altering Cell Migration. | E2F1 Drives Breast Cancer Metastasis by Regulating the Target Gene FGF13 and Altering Cell Migration.
Hollern DP, Swiatnicki MR, Rennhack JP, Misek SA, Matson BC, McAuliff A, Gallo KA, Caron KM, Andrechek ER., Free PMC Article | 10/24/2020 |
| Heterozygous Fgf13 knockouts fed normal chow. | Knockout of the X-linked Fgf13 in the hypothalamic paraventricular nucleus impairs sympathetic output to brown fat and causes obesity.
Sinden DS, Holman CD, Bare CJ, Sun X, Gade AR, Cohen DE, Pitt GS., Free PMC Article | 05/30/2020 |
| High FGF13 expression is associated with glioma cell invasion. | Fibroblast growth factor 13 regulates glioma cell invasion and is important for bevacizumab-induced glioma invasion.
Otani Y, Ichikawa T, Kurozumi K, Inoue S, Ishida J, Oka T, Shimizu T, Tomita Y, Hattori Y, Uneda A, Matsumoto Y, Michiue H, Date I. | 03/16/2019 |
| Autism-related protein MeCP2 regulates FGF13 expression and emotional behaviors | Autism-related protein MeCP2 regulates FGF13 expression and emotional behaviors.
Yuan B, Cheng TL, Yang K, Zhang X, Qiu Z. | 12/22/2018 |
| FHF2 has an essential role in dictating myocardial excitability and conduction that safeguards against temperature-sensitive conduction failure | Fhf2 gene deletion causes temperature-sensitive cardiac conduction failure.
Park DS, Shekhar A, Marra C, Lin X, Vasquez C, Solinas S, Kelley K, Morley G, Goldfarb M, Fishman GI., Free PMC Article | 10/6/2018 |
| regulator of caveolae-mediated mechanoprotection and adaptive hypertrophic signaling in cardiomyocytes | Inducible Fgf13 ablation enhances caveolae-mediated cardioprotection during cardiac pressure overload.
Wei EQ, Sinden DS, Mao L, Zhang H, Wang C, Pitt GS., Free PMC Article | 05/19/2018 |
| identified two novel native phosphorylation sites in the C terminus of NaV1.5 that impair FGF13-dependent regulation of channel inactivation and may contribute to CaMKIIdeltac-dependent arrhythmogenic disorders in failing hearts. | C-terminal phosphorylation of Na(V)1.5 impairs FGF13-dependent regulation of channel inactivation.
Burel S, Coyan FC, Lorenzini M, Meyer MR, Lichti CF, Brown JH, Loussouarn G, Charpentier F, Nerbonne JM, Townsend RR, Maier LS, Marionneau C., Free PMC Article | 10/28/2017 |
| the FGF13/Nav1.7 complex is essential for sustaining the transmission of noxious heat signals | FGF13 Selectively Regulates Heat Nociception by Interacting with Na(v)1.7.
Yang L, Dong F, Yang Q, Yang PF, Wu R, Wu QF, Wu D, Li CL, Zhong YQ, Lu YJ, Cheng X, Xu FQ, Chen L, Bao L, Zhang X. | 08/26/2017 |
| These results implicate that FGF13 is a critical cardiac Na(+) channel modulator and Fgf13 knockout mice have increased arrhythmia susceptibility in the setting of Na(+) channel blockade. | Conditional knockout of Fgf13 in murine hearts increases arrhythmia susceptibility and reveals novel ion channel modulatory roles.
Wang X, Tang H, Wei EQ, Wang Z, Yang J, Yang R, Wang S, Zhang Y, Pitt GS, Zhang H, Wang C., Free PMC Article | 06/3/2017 |
| FGF13 down-regulated Spry1 protein expression, activating the ERK1/2 pathway by phosphorylation and leading to C2C12 cell differentiation inhibition. | FGF13 regulates proliferation and differentiation of skeletal muscle by down-regulating Spry1.
Lu H, Shi X, Wu G, Zhu J, Song C, Zhang Q, Yang G., Free PMC Article | 11/21/2015 |
| Fibroblast growth factor homologous factors (FGF11-14) modulate cardiac calcium channels. | Fibroblast growth factor homologous factors modulate cardiac calcium channels.
Hennessey JA, Wei EQ, Pitt GS., Free PMC Article | 02/8/2014 |
| FGF13 has a role in hair follicle growth and in the hair cycle | Position effect on FGF13 associated with X-linked congenital generalized hypertrichosis.
DeStefano GM, Fantauzzo KA, Petukhova L, Kurban M, Tadin-Strapps M, Levy B, Warburton D, Cirulli ET, Han Y, Sun X, Shen Y, Shirazi M, Jobanputra V, Cepeda-Valdes R, Cesar Salas-Alanis J, Christiano AM., Free PMC Article | 07/20/2013 |
| Genetic deletion of FGF13 in mice results in neuronal migration defects in both the neocortex and the hippocampus. FGF13-deficient mice also exhibit weakened learning and memory. | Fibroblast growth factor 13 is a microtubule-stabilizing protein regulating neuronal polarization and migration.
Wu QF, Yang L, Li S, Wang Q, Yuan XB, Gao X, Bao L, Zhang X. | 09/8/2012 |
| Fibroblast growth factor homologous factor 13 regulates Na(V)1.5 sodium channels and conduction velocity in murine hearts. | Fibroblast growth factor homologous factor 13 regulates Na+ channels and conduction velocity in murine hearts.
Wang C, Hennessey JA, Kirkton RD, Wang C, Graham V, Puranam RS, Rosenberg PB, Bursac N, Pitt GS., Free PMC Article | 11/12/2011 |
| FGF-13 may play a role in regulating the function of cells in the bulge region and basal layer of the epidermis. | Bulge- and basal layer-specific expression of fibroblast growth factor-13 (FHF-2) in mouse skin.
Kawano M, Suzuki S, Suzuki M, Oki J, Imamura T. | 01/21/2010 |