CRYAB suppresses ferroptosis and promotes osteogenic differentiation of human bone marrow stem cells via binding and stabilizing FTH1.
Tian B, Li X, Li W, Shi Z, He X, Wang S, Zhu X, Shi N, Li Y, Wan P, Zhu C., Free PMC Article

TGFβ1-Induced Fibrotic Responses of Conjunctival Fibroblasts through the Wnt/β-Catenin/CRYAB Signaling Pathway.
Wang X, Chen K, Yao Y, Lin Y, Yang J, Zhu Y, Zhou B.

Modulation of Alzheimer's Disease Aβ40 Fibril Polymorphism by the Small Heat Shock Protein αB-Crystallin.
Rodina N, Hornung S, Sarkar R, Suladze S, Peters C, Schmid PWN, Niu Z, Haslbeck M, Buchner J, Kapurniotu A, Reif B., Free PMC Article

A computational study of the R120G mutation in human αB-crystallin: implications for structural stability and functionality.
Darvazi M, Ghorbani M, Ramazi S, Allahverdi A, Abdolmaleki P.

Unraveling the impact of the p.R107L mutation on the structure and function of human αB-Crystallin: Implications for cataract formation.
Nasiri F, Ebrahimi P, Shahsavani MB, Barati A, Zarei I, Hong J, Hoshino M, Moosavi-Movahedi AA, Yousefi R.

[Research on the anti-tumor effects of CRYAB in prostate cancer].
Zhang CL, Hu Y, Wang DX, Yang Q, Chang DH.

Insights into the dual nature of αB-crystallin chaperone activity from the p.P39L mutant at the N-terminal region.
Barati A, Rezaei Somee L, Shahsavani MB, Ghasemi A, Hoshino M, Hong J, Saboury AA, Moosavi-Movahedi AA, Agnetti G, Yousefi R., Free PMC Article

CRYAB stop-loss variant causes rare syndromic dilated cardiomyopathy with congenital cataract: expanding the phenotypic and mutational spectrum of alpha-B crystallinopathy.
Ha C, Kim D, Bak M, Park JH, Kim YG, Jang JH, Kim JW, Choi JO, Jang MA.

Role of the Alpha-B-Crystallin Protein in Cardiomyopathic Disease.
Thorkelsson A, Chin MT., Free PMC Article

Understanding the structural and functional changes and biochemical pathomechanism of the cardiomyopathy-associated p.R123W mutation in human αB-crystallin.
Somee LR, Barati A, Shahsavani MB, Hoshino M, Hong J, Kumar A, Moosavi-Movahedi AA, Amanlou M, Yousefi R.

Single cell sequencing revealed the mechanism of CRYAB in glioma and its diagnostic and prognostic value.
Cai HB, Zhao MY, Li XH, Li YQ, Yu TH, Wang CZ, Wang LN, Xu WY, Liang B, Cai YP, Zhang F, Hong WM., Free PMC Article

HspB5 Chaperone Structure and Activity Are Modulated by Chemical-Scale Interactions in the ACD Dimer Interface.
Wang C, Teng L, Liu ZS, Kamalova A, McMenimen KA., Free PMC Article

Mutations in alpha-B-crystallin cause autosomal dominant axonal Charcot-Marie-Tooth disease with congenital cataracts.
Cortese A, Currò R, Ronco R, Blake J, Rossor AM, Bugiardini E, Laurà M, Warner T, Yousry T, Poh R, Polke J, Rebelo A, Dohrn MF, Saporta M, Houlden H, Zuchner S, Reilly MM., Free PMC Article

Desmin and its molecular chaperone, the αB-crystallin: How post-translational modifications modulate their functions in heart and skeletal muscles?
Claeyssen C, Bulangalire N, Bastide B, Agbulut O, Cieniewski-Bernard C.

Mature human induced pluripotent stem cell-derived cardiomyocytes promote angiogenesis through alpha-B crystallin.
Tanaka Y, Kadota S, Zhao J, Kobayashi H, Okano S, Izumi M, Honda Y, Ichimura H, Shiba N, Uemura T, Wada Y, Chuma S, Nakada T, Tohyama S, Fukuda K, Yamada M, Seto T, Kuwahara K, Shiba Y., Free PMC Article

Investigating the role of double mutations R12C/P20R, and R12C/R69C on structure, chaperone-like activity, and amyloidogenic properties of human αB-crystallin.
Khaleghinejad SH, Shahsavani MB, Ghahramani M, Yousefi R.

Human Mutated MYOT and CRYAB Genes Cause a Myopathic Phenotype in Zebrafish.
Cannone E, Guglielmi V, Marchetto G, Tobia C, Gnutti B, Cisterna B, Tonin P, Barbon A, Vattemi G, Schiavone M., Free PMC Article

The structural and functional consequences of melatonin and serotonin on human αB-crystallin and their dual role in the eye lens transparency.
Nourazaran M, Yousefi R, Moosavi-Movahedi F, Panahi F, Hong J, Moosavi-Movahedi AA.

Cross-reactive EBNA1 immunity targets alpha-crystallin B and is associated with multiple sclerosis.
Thomas OG, Bronge M, Tengvall K, Akpinar B, Nilsson OB, Holmgren E, Hessa T, Gafvelin G, Khademi M, Alfredsson L, Martin R, Guerreiro-Cacais AO, Grönlund H, Olsson T, Kockum I., Free PMC Article

Effects of the CRYAB gene on stem cell-like properties of colorectal cancer and its mechanism.
Dai A, Guo X, Yang X, Li M, Fu Y, Sun Q.

Increased chaperone activity of human α‌B-crystallin with incomplete oxidation as a new defense mechanism against oxidative stress.
Ghahramani M, Shahsavani MB, Yousefi R.

In high-grade ovarian carcinoma, platinum-sensitive tumor recurrence and acquired-resistance derive from quiescent residual cancer cells that overexpress CRYAB, CEACAM6, and SOX2.
du Manoir S, Delpech H, Orsetti B, Jacot W, Pirot N, Noel J, Colombo PE, Sardet C, Theillet C.

Alpha-crystallin B chains enhance cell migration in basal-like 2 triple-negative breast cancer cells.
Yang L, Higashisaka K, Haga Y, Tsujino H, Nagano K, Tsutsumi Y.

Cluster analyses of the TCGA and a TMA dataset using the coexpression of HSP27 and CRYAB improves alignment with clinical-pathological parameters of breast cancer and suggests different epichaperome influences for each sHSP.
Quinlan PR, Figeuredo G, Mongan N, Jordan LB, Bray SE, Sreseli R, Ashfield A, Mitsch J, van den Ijssel P, Thompson AM, Quinlan RA., Free PMC Article

Limb-bud and heart (LBH) inhibits cellular migration, invasion and epithelial-mesenchymal transition in nasopharyngeal carcinoma via downregulating αB-crystallin expression.
Wu A, Zhang L, Luo N, Zhang L, Li L, Liu Q.