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    CRY1 cryptochrome circadian regulator 1 [ Homo sapiens (human) ]

    Gene ID: 1407, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Cryptochrome 1 regulates ovarian granulosa cell senescence through NCOA4-mediated ferritinophagy.

    Cryptochrome 1 regulates ovarian granulosa cell senescence through NCOA4-mediated ferritinophagy.
    Ma J, Chen S, Liu J, Liao Y, Li L, Wang CC, Song S, Feng R, Hu H, Quan S.

    05/3/2024
    Circadian modulation of glucose utilization via CRY1-mediated repression of Pdk1 expression.

    Circadian modulation of glucose utilization via CRY1-mediated repression of Pdk1 expression.
    Chiou YY, Lee CY, Yang HW, Cheng WC, Ji KD., Free PMC Article

    02/27/2024
    Cry1Delta11 mutation induces ADHD-like symptoms through hyperactive dopamine D1 receptor signaling.

    Cry1Δ11 mutation induces ADHD-like symptoms through hyperactive dopamine D1 receptor signaling.
    Liu D, Xie Z, Gu P, Li X, Zhang Y, Wang X, Chen Z, Deng S, Shu Y, Li JD., Free PMC Article

    08/25/2023
    The interaction between CRY1 Polymorphism and Alternative Healthy Eating Index (AHEI) on cardiovascular risk factors in overweight women and women with obesity: a cross-sectional study.

    The interaction between CRY1 Polymorphism and Alternative Healthy Eating Index (AHEI) on cardiovascular risk factors in overweight women and women with obesity: a cross-sectional study.
    Firouzabadi FD, Mirzababaei A, Shiraseb F, Tangestani H, Mirzaei K., Free PMC Article

    08/16/2023
    Circadian Gene cry Controls Tumorigenesis through Modulation of Myc Accumulation in Glioblastoma Cells.

    Circadian Gene cry Controls Tumorigenesis through Modulation of Myc Accumulation in Glioblastoma Cells.
    Jarabo P, de Pablo C, González-Blanco A, Casas-Tintó S., Free PMC Article

    03/12/2022
    Cryptochrome 1 is modulated by blue light in human keratinocytes and exerts positive impact on human hair growth.

    Cryptochrome 1 is modulated by blue light in human keratinocytes and exerts positive impact on human hair growth.
    Buscone S, Mardaryev AN, Westgate GE, Uzunbajakava NE, Botchkareva NV.

    02/26/2022
    CRY1 Regulates Chemoresistance in Association With NANOG by Inhibiting Apoptosis via STAT3 Pathway in Patients With Cervical Cancer.

    CRY1 Regulates Chemoresistance in Association With NANOG by Inhibiting Apoptosis via STAT3 Pathway in Patients With Cervical Cancer.
    Han GH, Kim J, Yun H, Cho H, Chung JY, Kim JH, Hewitt SM., Free PMC Article

    02/19/2022
    Variants of the cry 1 gene may influence the effect of fat intake on resting metabolic rate in women with overweight of obesity: a cross-sectional study.

    Variants of the cry 1 gene may influence the effect of fat intake on resting metabolic rate in women with overweight of obesity: a cross-sectional study.
    Mirzababaei A, Daneshzad E, Shiraseb F, Pourreza S, Setayesh L, Clark CCT, Tangestani H, Abaj F, Yarizadeh H, Mirzaei K., Free PMC Article

    02/5/2022
    An observational study investigating the CRY1Delta11 variant associated with delayed sleep-wake patterns and circadian metabolic output.

    An observational study investigating the CRY1Δ11 variant associated with delayed sleep-wake patterns and circadian metabolic output.
    Smieszek SP, Brzezynski JL, Kaden AR, Shinn JA, Wang J, Xiao C, Polymeropoulos C, Özçelik T, Polymeropoulos MH., Free PMC Article

    01/29/2022
    The molecular clock gene cryptochrome 1 (CRY1) and its role in cluster headache.

    The molecular clock gene cryptochrome 1 (CRY1) and its role in cluster headache.
    Fourier C, Ran C, Sjöstrand C, Waldenlind E, Steinberg A, Belin AC., Free PMC Article

    01/22/2022
    RNF38 inhibits osteosarcoma cell proliferation by binding to CRY1.

    RNF38 inhibits osteosarcoma cell proliferation by binding to CRY1.
    Zhou J, Tang ZY, Sun XL.

    01/8/2022
    Circadian clock protein CRY1 prevents paclitaxelinduced senescence of bladder cancer cells by promoting p53 degradation.

    Circadian clock protein CRY1 prevents paclitaxel‑induced senescence of bladder cancer cells by promoting p53 degradation.
    Jia M, Su B, Mo L, Qiu W, Ying J, Lin P, Yang B, Li D, Wang D, Xu L, Li H, Zhou Z, Li X, Li J., Free PMC Article

    10/23/2021
    Analysis of Evolution and Ethnic Diversity at Glucose-Associated SNPs of Circadian Clock-Related Loci with Cryptochrome 1, Cryptochrome 2, and Melatonin receptor 1B.

    Analysis of Evolution and Ethnic Diversity at Glucose-Associated SNPs of Circadian Clock-Related Loci with Cryptochrome 1, Cryptochrome 2, and Melatonin receptor 1B.
    Yoshiuchi I.

    10/2/2021
    Assessment of Selected Clock Proteins (CLOCK and CRY1) and Their Relationship with Biochemical, Anthropometric, and Lifestyle Parameters in Hypertensive Patients.

    Assessment of Selected Clock Proteins (CLOCK and CRY1) and Their Relationship with Biochemical, Anthropometric, and Lifestyle Parameters in Hypertensive Patients.
    Mikulska AA, Grzelak T, Pelczyńska M, Bogdański P, Czyżewska K., Free PMC Article

    10/2/2021
    Increase of Cry 1 expression is a common phenomenon of the disturbed circadian clock in ischemic stroke and opioid addiction.

    Increase of Cry 1 expression is a common phenomenon of the disturbed circadian clock in ischemic stroke and opioid addiction.
    Roy K, Maji D, Deb I.

    08/28/2021
    Cancer, hear my battle CRY.

    Cancer, hear my battle CRY.
    Chan AB, Lamia KA., Free PMC Article

    08/21/2021
    Suppression of circadian clock protein cryptochrome 2 promotes osteoarthritis.

    Suppression of circadian clock protein cryptochrome 2 promotes osteoarthritis.
    Bekki H, Duffy T, Okubo N, Olmer M, Alvarez-Garcia O, Lamia K, Kay S, Lotz M., Free PMC Article

    07/31/2021
    Human CRY1 variants associate with attention deficit/hyperactivity disorder.

    Human CRY1 variants associate with attention deficit/hyperactivity disorder.
    Onat OE, Kars ME, Gül Ş, Bilguvar K, Wu Y, Özhan A, Aydın C, Başak AN, Trusso MA, Goracci A, Fallerini C, Renieri A, Casanova JL, Itan Y, Atbaşoğlu CE, Saka MC, Kavaklı İH, Özçelik T., Free PMC Article

    02/6/2021
    The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair.

    The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair.
    Shafi AA, McNair CM, McCann JJ, Alshalalfa M, Shostak A, Severson TM, Zhu Y, Bergman A, Gordon N, Mandigo AC, Chand SN, Gallagher P, Dylgjeri E, Laufer TS, Vasilevskaya IA, Schiewer MJ, Brunner M, Feng FY, Zwart W, Knudsen KE., Free PMC Article

    01/30/2021
    The human CRY1 tail controls circadian timing by regulating its association with CLOCK:BMAL1.

    The human CRY1 tail controls circadian timing by regulating its association with CLOCK:BMAL1.
    Parico GCG, Perez I, Fribourgh JL, Hernandez BN, Lee HW, Partch CL., Free PMC Article

    01/9/2021
    The Universally Conserved Residues Are Not Universally Required for Stable Protein Expression or Functions of Cryptochromes.

    The Universally Conserved Residues Are Not Universally Required for Stable Protein Expression or Functions of Cryptochromes.
    Liu H, Su T, He W, Wang Q, Lin C., Free PMC Article

    10/24/2020
    CRY1 regulates the proliferation and differentiation of osteoblastic cells in an AKT and ERK-dependent manner.

    Cryptochrome 1 Regulates Osteoblast Differentiation via the AKT Kinase and Extracellular Signal-Regulated Kinase Signaling Pathways.
    Zhou L, He J, Sun S, Yu Y, Zhang T, Wang M.

    07/4/2020
    this study identified two distinct light chain 3 (LC3)-interacting region (LIR) motifs on CRY1 that exert circadian glycemic control by regulating CRY1 degradation, revealing LIRs as potential targets for controlling hyperglycemia.

    Autophagy Regulates the Liver Clock and Glucose Metabolism by Degrading CRY1.
    Toledo M, Batista-Gonzalez A, Merheb E, Aoun ML, Tarabra E, Feng D, Sarparanta J, Merlo P, Botrè F, Schwartz GJ, Pessin JE, Singh R., Free PMC Article

    10/5/2019
    In colorectal cancer, higher expression of cry1 in the right-sided colon tumor tissue was associated with worse survival in women and the expression of cry1 in the left-sided colorectum was significantly higher in the adjacent tissue compared to tumor in men but not in women

    The expression of clock genes cry1 and cry2 in human colorectal cancer and tumor adjacent tissues correlates differently dependent on tumor location.
    Hasakova K, Vician M, Reis R, Zeman M, Herichova I.

    07/6/2019
    Neuroglobin correlates with cryptochrome-1 in obstructive sleep apnea with primary aldosteronism

    Neuroglobin correlates with cryptochrome-1 in obstructive sleep apnea with primary aldosteronism.
    Tedjasukmana R, Purba JS, Wanandi SI, Suyatna FD., Free PMC Article

    03/2/2019
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