| S100A16 is a potential target for reshaping the tumor microenvironment in the hypoxic context of liver cancer. | S100A16 is a potential target for reshaping the tumor microenvironment in the hypoxic context of liver cancer.
Yang D, Zhao F, Zhou Y, Zhang Y, Shen J, Yu B, Zhao K, Ding Y. | 06/10/2024 |
| An Update on S100A16 in Human Cancer. | An Update on S100A16 in Human Cancer.
Basnet S, Vallenari EM, Maharjan U, Sharma S, Schreurs O, Sapkota D., Free PMC Article | 08/2/2023 |
| S100 Calcium Binding Protein A16 Promotes Cell Proliferation by triggering LATS1 ubiquitin degradation mediated by CUL4A ligase to inhibit Hippo pathway in Glioma development. | S100 Calcium Binding Protein A16 Promotes Cell Proliferation by triggering LATS1 ubiquitin degradation mediated by CUL4A ligase to inhibit Hippo pathway in Glioma development.
Hu Y, Zhang R, Lu S, Zhang W, Wang D, Ge Y, Jiang F, Qin X, Liu Y., Free PMC Article | 05/15/2023 |
| New progress with calcium-binding protein S100A16 in digestive system disease. | New progress with calcium-binding protein S100A16 in digestive system disease.
Li B, Zhu W, Shi D, Che H, Lyu Q, Jiang B. | 03/2/2023 |
| Calbindin S100A16 Promotes Renal Cell Carcinoma Progression and Angiogenesis via the VEGF/VEGFR2 Signaling Pathway. | Calbindin S100A16 Promotes Renal Cell Carcinoma Progression and Angiogenesis via the VEGF/VEGFR2 Signaling Pathway.
Wang N, Wang R, Tang J, Gao J, Fang Z, Zhang M, Shen X, Lu L, Chen Y., Free PMC Article | 10/15/2022 |
| Downregulated Calcium-Binding Protein S100A16 and HSP27 in Placenta-Derived Multipotent Cells Induce Functional Astrocyte Differentiation. | Downregulated Calcium-Binding Protein S100A16 and HSP27 in Placenta-Derived Multipotent Cells Induce Functional Astrocyte Differentiation.
Cheng YC, Huang CJ, Ku WC, Guo SL, Tien LT, Lee YJ, Chien CC., Free PMC Article | 04/16/2022 |
| The interaction of S100A16 and GRP78 actives endoplasmic reticulum stress-mediated through the IRE1alpha/XBP1 pathway in renal tubulointerstitial fibrosis. | The interaction of S100A16 and GRP78 actives endoplasmic reticulum stress-mediated through the IRE1α/XBP1 pathway in renal tubulointerstitial fibrosis.
Jin R, Zhao A, Han S, Zhang D, Sun H, Li M, Su D, Liang X., Free PMC Article | 02/5/2022 |
| S100A16 promotes metastasis and progression of pancreatic cancer through FGF19-mediated AKT and ERK1/2 pathways. | S100A16 promotes metastasis and progression of pancreatic cancer through FGF19-mediated AKT and ERK1/2 pathways.
Fang D, Zhang C, Xu P, Liu Y, Mo X, Sun Q, Abdelatty A, Hu C, Xu H, Zhou G, Xia H, Lan L. | 01/22/2022 |
| S100A16 induces epithelial-mesenchymal transition in human PDAC cells and is a new therapeutic target for pancreatic cancer treatment that synergizes with gemcitabine. | S100A16 induces epithelial-mesenchymal transition in human PDAC cells and is a new therapeutic target for pancreatic cancer treatment that synergizes with gemcitabine.
Li T, Ren T, Huang C, Li Y, Yang P, Che G, Luo L, Chen Y, Peng S, Lin Y, Zeng L. | 09/18/2021 |
| S100A16 suppresses the proliferation, migration and invasion of colorectal cancer cells in part via the JNK/p38 MAPK pathway. | S100A16 suppresses the proliferation, migration and invasion of colorectal cancer cells in part via the JNK/p38 MAPK pathway.
Ou S, Liao Y, Shi J, Tang J, Ye Y, Wu F, Wang W, Fei J, Xie F, Bai L., Free PMC Article | 05/8/2021 |
| Interaction of calcium binding protein S100A16 with myosin-9 promotes cytoskeleton reorganization in renal tubulointerstitial fibrosis. | Interaction of calcium binding protein S100A16 with myosin-9 promotes cytoskeleton reorganization in renal tubulointerstitial fibrosis.
Sun H, Zhao A, Li M, Dong H, Sun Y, Zhang X, Zhu Q, Bukhari AA, Cao C, Su D, Liu Y, Liang X., Free PMC Article | 04/13/2021 |
| Inhibition assays suggested these two signalling pathways participated in the S100A16-mediated proliferation and survival effects in B-cell ALL cell lines. | S100A16 suppresses the growth and survival of leukaemia cells and correlates with relapse and relapse free survival in adults with Philadelphia chromosome-negative B-cell acute lymphoblastic leukaemia.
Zhang J, Lu WY, Zhang JM, Lu RQ, Wu LX, Qin YZ, Liu YR, Lai YY, Jiang H, Jiang Q, Jiang B, Xu LP, Zhang XH, Huang XJ, Ruan GR, Liu KY. | 06/13/2020 |
| S100A16 could promote the proliferation, migration, and tumor angiogenesis of HeLa cells by regulating the phosphatidylinositol 3 kinase/protein kinase B signaling pathways. | S100A16 Regulates HeLa Cell through the Phosphatidylinositol 3 Kinase (PI3K)/AKT Signaling Pathway.
Zhang H, Yang Y, Ma X, Xin W, Fan X., Free PMC Article | 06/6/2020 |
| MANF showed not only transient but also long-lasting neuroprotective pro | Brain microvascular endothelial cell exosome-mediated S100A16 up-regulation confers small-cell lung cancer cell survival in brain.
Xu ZH, Miao ZW, Jiang QZ, Gan DX, Wei XG, Xue XZ, Li JQ, Zheng F, Qin XX, Fang WG, Chen YH, Li B. | 10/5/2019 |
| S100A16 might promote lipid synthesis in HepG2 cells through endoplasmic reticulum stress HSPA5/IRE1alpha-XBP1 pathway. | [S100 calcium binding protein A16 promotes fat synthesis through endoplasmic reticulum stress in HepG2 cells].
Kan JB, Shen GQ, Yang J, Tong P, Zhang RH, Liang XB, Su DM, Li D, Liu Y. | 08/17/2019 |
| Our results suggest that the subcellular localization of S100A16 and S100A16 mRNA expression levels is a promising prognostic marker for lung adenocarcinoma. | Prognostic significance of S100A16 subcellular localization in lung adenocarcinoma.
Kobayashi M, Nagashio R, Saito K, Aguilar-Bonavides C, Ryuge S, Katono K, Igawa S, Tsuchiya B, Jiang SX, Ichinoe M, Murakumo Y, Saegusa M, Satoh Y, Sato Y. | 03/9/2019 |
| Low S100A16 expression is associated with colorectal cancer. | S100A16 is a prognostic marker for colorectal cancer.
Sun X, Wang T, Zhang C, Ning K, Guan ZR, Chen SX, Hong TT, Hua D. | 03/10/2018 |
| Data show that overexpression of S100 calcium binding protein A16 protein (S100A16) activated AKT protein and ERK signaling pathways. | S100A16 promotes cell proliferation and metastasis via AKT and ERK cell signaling pathways in human prostate cancer.
Zhu W, Xue Y, Liang C, Zhang R, Zhang Z, Li H, Su D, Liang X, Zhang Y, Huang Q, Liu M, Li L, Li D, Zhao AZ, Liu Y. | 02/25/2017 |
| These results indicate that S100 calcium binding protein A16 is a differentiation promoting protein and might function as a tumor suppressor in oral squamous cell carcinoma. | S100A16 promotes differentiation and contributes to a less aggressive tumor phenotype in oral squamous cell carcinoma.
Sapkota D, Bruland O, Parajuli H, Osman TA, Teh MT, Johannessen AC, Costea DE., Free PMC Article | 05/21/2016 |
| Co-expression of S100A14 and S100A16 correlates with a poor prognosis in human breast cancer and promotes cancer cell invasion | Co-expression of S100A14 and S100A16 correlates with a poor prognosis in human breast cancer and promotes cancer cell invasion.
Tanaka M, Ichikawa-Tomikawa N, Shishito N, Nishiura K, Miura T, Hozumi A, Chiba H, Yoshida S, Ohtake T, Sugino T., Free PMC Article | 01/2/2016 |
| S100A16 had a potential function to regulate some embryonic transcription factors to promote epithelial-mensenchymal transition in breast cancer cells which may be an important target site for the therapy of breast cancer. | Up-regulation of S100A16 expression promotes epithelial-mesenchymal transition via Notch1 pathway in breast cancer.
Zhou W, Pan H, Xia T, Xue J, Cheng L, Fan P, Zhang Y, Zhu W, Xue Y, Liu X, Ding Q, Liu Y, Wang S., Free PMC Article | 07/25/2015 |
| The presence of hydrophobic interactions stronger than for other S100 proteins, present in the closed form of S100A16 between the third and fourth helices, likely make the closed structure of the second EF-hand particularly stable. | Structural characterization of human S100A16, a low-affinity calcium binder.
Babini E, Bertini I, Borsi V, Calderone V, Hu X, Luchinat C, Parigi G. | 05/14/2011 |