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    Esr1 estrogen receptor 1 (alpha) [ Mus musculus (house mouse) ]

    Gene ID: 13982, updated on 21-Aug-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Knockdown of Esr1 from DRD1-Rich Brain Regions Affects Adipose Tissue Metabolism: Potential Crosstalk between Nucleus Accumbens and Adipose Tissue.

    Knockdown of Esr1 from DRD1-Rich Brain Regions Affects Adipose Tissue Metabolism: Potential Crosstalk between Nucleus Accumbens and Adipose Tissue.
    Shay D, Welly R, Mao J, Kinkade J, Brown JK, Rosenfeld CS, Vieira-Potter VJ., Free PMC Article

    07/18/2024
    An estrogen receptor alpha-derived peptide improves glucose homeostasis during obesity.

    An estrogen receptor α-derived peptide improves glucose homeostasis during obesity.
    Yang W, Jiang W, Liao W, Yan H, Ai W, Pan Q, Brashear WA, Xu Y, He L, Guo S., Free PMC Article

    05/7/2024
    Female-specific dysfunction of sensory neocortical circuits in a mouse model of autism mediated by mGluR5 and estrogen receptor alpha.

    Female-specific dysfunction of sensory neocortical circuits in a mouse model of autism mediated by mGluR5 and estrogen receptor α.
    Molinaro G, Bowles JE, Croom K, Gonzalez D, Mirjafary S, Birnbaum SG, Razak KA, Gibson JR, Huber KM., Free PMC Article

    04/30/2024
    Sex-specific regulation of miR-22 and ERalpha in white adipose tissue of obese dam's female offspring impairs the early postnatal development of functional beige adipocytes in mice.

    Sex-specific regulation of miR-22 and ERα in white adipose tissue of obese dam's female offspring impairs the early postnatal development of functional beige adipocytes in mice.
    de Sousa É, de Mendonça M, Bolin AP, de Oliveira NP, Real CC, Hu X, Huang ZP, Wang DZ, Rodrigues AC.

    04/16/2024
    Linking alterations in estrogen receptor expression to memory deficits and depressive behavior in an ovariectomy mouse model.

    Linking alterations in estrogen receptor expression to memory deficits and depressive behavior in an ovariectomy mouse model.
    Baek DC, Kang JY, Lee JS, Lee EJ, Son CG., Free PMC Article

    03/27/2024
    Increased palmitoylation improves estrogen receptor alpha-dependent hippocampal synaptic deficits in a mouse model of synucleinopathy.

    Increased palmitoylation improves estrogen receptor alpha-dependent hippocampal synaptic deficits in a mouse model of synucleinopathy.
    Moors TE, Li S, McCaffery TD, Ho GPH, Bechade PA, Pham LN, Ericsson M, Nuber S., Free PMC Article

    11/20/2023
    Mammary gland development and EDC-driven cancer susceptibility in mesenchymal ERalpha-knockout mice.

    Mammary gland development and EDC-driven cancer susceptibility in mesenchymal ERα-knockout mice.
    Wormsbaecher C, Cumbia BM, Amurgis EG, Poska JM, Price MR, Mo XM, Knoblaugh SE, Kurita T, Burd CJ., Free PMC Article

    11/18/2023
    Aberrant activation of estrogen receptor-alpha signaling in Mettl14-deficient uteri impairs embryo implantation.

    Aberrant activation of estrogen receptor-α signaling in Mettl14-deficient uteri impairs embryo implantation.
    Kobayashi R, Kawabata-Iwakawa R, Terakawa J, Sugiyama M, Morita S, Horii T, Hatada I.

    08/31/2023
    The influence of estrogen response element ERalpha signaling in the control of feeding behaviors in male and female mice.

    The influence of estrogen response element ERα signaling in the control of feeding behaviors in male and female mice.
    Yasrebi A, Regan D, Roepke TA., Free PMC Article

    08/25/2023
    Endothelial ERalpha promotes glucose tolerance by enhancing endothelial insulin transport to skeletal muscle.

    Endothelial ERα promotes glucose tolerance by enhancing endothelial insulin transport to skeletal muscle.
    Sacharidou A, Chambliss K, Peng J, Barrera J, Tanigaki K, Luby-Phelps K, Özdemir İ, Khan S, Sirsi SR, Kim SH, Katzenellenbogen BS, Katzenellenbogen JA, Kanchwala M, Sathe AA, Lemoff A, Xing C, Hoyt K, Mineo C, Shaul PW., Free PMC Article

    08/23/2023
    The G-protein-coupled estrogen receptor, a gene co-expressed with ERalpha in breast tumors, is regulated by estrogen-ERalpha signalling in ERalpha positive breast cancer cells.

    The G-protein-coupled estrogen receptor, a gene co-expressed with ERα in breast tumors, is regulated by estrogen-ERα signalling in ERα positive breast cancer cells.
    Pal U, Manjegowda MC, Singh N, Saikia S, Philip BS, Jyoti Kalita D, Kumar Rai A, Sarma A, Raphael V, Modi D, Chandra Kataki A, Mukund Limaye A.

    07/12/2023
    Expression Analysis of Lipocalin 2 (LCN2) in Reproductive and Non-Reproductive Tissues of Esr1-Deficient Mice.

    Expression Analysis of Lipocalin 2 (LCN2) in Reproductive and Non-Reproductive Tissues of Esr1-Deficient Mice.
    Kessel JC, Weiskirchen R, Schröder SK., Free PMC Article

    06/13/2023
    Time-Restricted Feeding Ameliorates Uterine Epithelial Estrogen Receptor alpha Transcriptional Activity at the Time of Embryo Implantation in Mice Fed a High-Fat Diet.

    Time-Restricted Feeding Ameliorates Uterine Epithelial Estrogen Receptor α Transcriptional Activity at the Time of Embryo Implantation in Mice Fed a High-Fat Diet.
    Liu L, Zhuo Y, Zhang H, Li J, Jiang X, Han X, Chao J, Feng B, Che L, Xu S, Lin Y, Li J, Fang Z, Sun M, Luo T, Wu D, Hua L.

    06/9/2023
    Estrogen Receptor Alpha Gene (ESR1) Facilitates Th2-immune Response and Enhances Th2 Cytokines in Experimental Atopic Dermatitis Mice.

    Estrogen Receptor Alpha Gene (ESR1) Facilitates Th2-immune Response and Enhances Th2 Cytokines in Experimental Atopic Dermatitis Mice.
    Niu J, Zhou H, Tian R, Wang X.

    06/3/2023
    Activation function 2 (AF2) domain of estrogen receptor-alpha regulates mechanotransduction during bone fracture healing in estrogen-competent mice.

    Activation function 2 (AF2) domain of estrogen receptor-α regulates mechanotransduction during bone fracture healing in estrogen-competent mice.
    Steppe L, Krüger B, Tschaffon-Müller MEA, Ramge JM, Schoppa A, Ignatius A, Haffner-Luntzer M.

    05/22/2023
    Estrogen Receptor Alpha Splice Variants, Post-Translational Modifications, and Their Physiological Functions.

    Estrogen Receptor Alpha Splice Variants, Post-Translational Modifications, and Their Physiological Functions.
    Saito K, Cui H., Free PMC Article

    04/12/2023
    Activation of estrogen receptor alpha inhibits TLR4 signaling in macrophages and alleviates the instability of atherosclerotic plaques in the postmenopausal stage.

    Activation of estrogen receptor α inhibits TLR4 signaling in macrophages and alleviates the instability of atherosclerotic plaques in the postmenopausal stage.
    Meng Q, Bi Y, Feng H, Ding X, Zhang S, Chen Q, Wang L, Zhang Q, Li Y, Tong H, Wu L, Bian H.

    03/9/2023
    miR-34a-5p facilitates osteogenic differentiation of bone marrow mesenchymal stem cells and modulates bone metabolism by targeting HDAC1 and promoting ER-alpha transcription.

    miR-34a-5p facilitates osteogenic differentiation of bone marrow mesenchymal stem cells and modulates bone metabolism by targeting HDAC1 and promoting ER-α transcription.
    Sun D, Chen Y, Liu X, Huang G, Cheng G, Yu C, Fang J.

    03/8/2023
    Estrogen receptor 1 appears essential for fetal viability in a murine model of premature birth.

    Estrogen receptor 1 appears essential for fetal viability in a murine model of premature birth.
    Schmiedecke SS, Thagard AS, Edwards SM, Talley RL, Dornisch EM, Damicis JR, McLane M, Burd I, Napolitano PG, Ieronimakis N.

    02/27/2023
    ERalpha/ERbeta-directed CBS transcription mediates E2beta-stimulated hUAEC H2S production.

    ERα/ERβ-directed CBS transcription mediates E2β-stimulated hUAEC H2S production.
    Bai J, Lechuga TJ, Makhoul J, Yan H, Major C, Hameed A, Chen DB., Free PMC Article

    02/11/2023
    Low expression of ESR1 correlates with ascending aortic dilation and acute type A aortic dissection.

    Low expression of ESR1 correlates with ascending aortic dilation and acute type A aortic dissection.
    Zhang Y, Li Y, Miao S, Dai X, Chen L, Ma L.

    01/28/2023
    SIRT1 haplo-insufficiency results in reduced cortical bone thickness, increased porosity and decreased estrogen receptor alpha in bone in adult 129/Sv female mice.

    SIRT1 haplo-insufficiency results in reduced cortical bone thickness, increased porosity and decreased estrogen receptor alpha in bone in adult 129/Sv female mice.
    Artsi H, Cohen-Kfir E, Shahar R, Kalish-Achrai N, Lishinsky N, Dresner-Pollak R., Free PMC Article

    01/14/2023
    Overexpression of Estrogen Receptor alpha in Mammary Glands of Aging Mice Is Associated with a Proliferative Risk Signature and Generation of Estrogen Receptor alpha-Positive Mammary Adenocarcinomas.

    Overexpression of Estrogen Receptor α in Mammary Glands of Aging Mice Is Associated with a Proliferative Risk Signature and Generation of Estrogen Receptor α-Positive Mammary Adenocarcinomas.
    Furth PA, Wang W, Kang K, Rooney BL, Keegan G, Muralidaran V, Wong J, Shearer C, Zou X, Flaws JA., Free PMC Article

    12/31/2022
    Esr1 but Not CYP19A1 Overexpression in Mammary Epithelial Cells during Reproductive Senescence Induces Pregnancy-Like Proliferative Mammary Disease Responsive to Anti-Hormonals.

    Esr1 but Not CYP19A1 Overexpression in Mammary Epithelial Cells during Reproductive Senescence Induces Pregnancy-Like Proliferative Mammary Disease Responsive to Anti-Hormonals.
    Furth PA, Wang W, Kang K, Rooney BL, Keegan G, Muralidaran V, Zou X, Flaws JA., Free PMC Article

    12/31/2022
    Hypomorphism of a Novel Long ERalpha Isoform Causes Severe Reproductive Dysfunctions in Female Mice.

    Hypomorphism of a Novel Long ERα Isoform Causes Severe Reproductive Dysfunctions in Female Mice.
    Saito K, Dickey JE, Rodeghiero SR, Toth BA, Kelly MJ, Deng Y, Singh U, Deng G, Jiang J, Cui H., Free PMC Article

    10/29/2022
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