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    CREBBP CREB binding protein [ Homo sapiens (human) ]

    Gene ID: 1387, updated on 5-May-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    BCOR::CREBBP fusion in malignant neuroepithelial tumor of CNS expands the spectrum of methylation class CNS tumor with BCOR/BCOR(L1)-fusion.

    BCOR::CREBBP fusion in malignant neuroepithelial tumor of CNS expands the spectrum of methylation class CNS tumor with BCOR/BCOR(L1)-fusion.
    Ebrahimi A, Waha A, Schittenhelm J, Gohla G, Schuhmann MU, Pietsch T., Free PMC Article

    04/25/2024
    NOTCH1 and CREBBP co-mutations negatively affect the benefit of adjuvant therapy in completely resected EGFR-mutated NSCLC: translational research of phase III IMPACT study.

    NOTCH1 and CREBBP co-mutations negatively affect the benefit of adjuvant therapy in completely resected EGFR-mutated NSCLC: translational research of phase III IMPACT study.
    Ikeda S, Tsuboi M, Sakai K, Misumi T, Akamatsu H, Shoda H, Sakakura N, Nakamura A, Ohde Y, Hayashi H, Okishio K, Okada M, Yoshino I, Okami J, Takahashi K, Ikeda N, Tanahashi M, Tambo Y, Saito H, Toyooka S, Inokawa H, Chen-Yoshikawa T, Yokoyama T, Okamoto T, Yanagitani N, Oki M, Takahama M, Sawa K, Tada H, Nakagawa K, Mitsudomi T, Nishio K., Free PMC Article

    02/9/2024
    Molecular insight into CREBBP and TANGO2 variants causing intellectual disability.

    Molecular insight into CREBBP and TANGO2 variants causing intellectual disability.
    Hussain SI, Muhammad N, Khan N, Khan M, Fardous F, Tahir R, Yasin M, Khan SA, Saleha S, Muhammad N, Wasif N, Khan S.

    02/7/2024
    CBP and RAD21 Proteins Bind at the Termini of Forum Domains in Human Chromosomes.

    CBP and RAD21 Proteins Bind at the Termini of Forum Domains in Human Chromosomes.
    Tchurikov NA, Alembekov IR, Klushevskaya ES, Meilakh PB, Kretova AN, Managarova OD, Kravatskaya GI, Kravatsky YV.

    02/5/2024
    The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.

    The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.
    Krošel M, Gabathuler M, Moser L, Maciukiewicz M, Züllig T, Seifritz T, Tomšič M, Distler O, Ospelt C, Klein K., Free PMC Article

    10/12/2023
    beta-catenin/CBP activation of mTORC1 signaling promotes partial epithelial-mesenchymal states in head and neck cancer.

    β-catenin/CBP activation of mTORC1 signaling promotes partial epithelial-mesenchymal states in head and neck cancer.
    Reed ER, Jankowski SA, Spinella AJ, Noonan V, Haddad R, Nomoto K, Matsui J, Bais MV, Varelas X, Kukuruzinska MA, Monti S.,

    08/30/2023
    The transcriptional coactivator CBP/p300 is an evolutionarily conserved node that promotes longevity in response to mitochondrial stress.

    The transcriptional coactivator CBP/p300 is an evolutionarily conserved node that promotes longevity in response to mitochondrial stress.
    Li TY, Sleiman MB, Li H, Gao AW, Mottis A, Bachmann AM, El Alam G, Li X, Goeminne LJE, Schoonjans K, Auwerx J., Free PMC Article

    07/25/2023
    Emerging roles of p300/CBP in autophagy and autophagy-related human disorders.

    Emerging roles of p300/CBP in autophagy and autophagy-related human disorders.
    Xu Y, Wan W.

    06/22/2023
    Identification and verification of FN1, P4HA1 and CREBBP as potential biomarkers in human atrial fibrillation.

    Identification and verification of FN1, P4HA1 and CREBBP as potential biomarkers in human atrial fibrillation.
    Zhu M, Yan T, Zhu S, Weng F, Zhu K, Wang C, Guo C.

    05/14/2023
    Hypermethylation at CREBBP Is Associated with Cognitive Impairment in a Mexican American Cohort.

    Hypermethylation at CREBBP Is Associated with Cognitive Impairment in a Mexican American Cohort.
    Abraham Daniel A, Silzer T, Sun J, Zhou Z, Hall C, Phillips N, Barber R., Free PMC Article

    04/29/2023
    KMT2D acetylation by CREBBP reveals a cooperative functional interaction at enhancers in normal and malignant germinal center B cells.

    KMT2D acetylation by CREBBP reveals a cooperative functional interaction at enhancers in normal and malignant germinal center B cells.
    Vlasevska S, Garcia-Ibanez L, Duval R, Holmes AB, Jahan R, Cai B, Kim A, Mo T, Basso K, Soni RK, Bhagat G, Dalla-Favera R, Pasqualucci L., Free PMC Article

    03/16/2023
    SARS-CoV-2 infection activates CREB/CBP in cellular cyclic AMP-dependent pathways.

    SARS-CoV-2 infection activates CREB/CBP in cellular cyclic AMP-dependent pathways.
    Yang Q, Tang J, Cao J, Liu F, Fu M, Xue B, Zhou A, Chen S, Liu J, Zhou Y, Shi Y, Peng W, Chen X., Free PMC Article

    02/11/2023
    CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder.

    CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder.
    de Thonel A, Ahlskog JK, Daupin K, Dubreuil V, Berthelet J, Chaput C, Pires G, Leonetti C, Abane R, Barris LC, Leray I, Aalto AL, Naceri S, Cordonnier M, Benasolo C, Sanial M, Duchateau A, Vihervaara A, Puustinen MC, Miozzo F, Fergelot P, Lebigot É, Verloes A, Gressens P, Lacombe D, Gobbo J, Garrido C, Westerheide SD, David L, Petitjean M, Taboureau O, Rodrigues-Lima F, Passemard S, Sabéran-Djoneidi D, Nguyen L, Lancaster M, Sistonen L, Mezger V., Free PMC Article

    11/26/2022
    Identification of a reciprocal negative feedback loop between tau-modifying proteins MARK2 kinase and CBP acetyltransferase.

    Identification of a reciprocal negative feedback loop between tau-modifying proteins MARK2 kinase and CBP acetyltransferase.
    Tabassum Z, Tseng JH, Isemann C, Tian X, Chen Y, Herring LE, Cohen TJ., Free PMC Article

    07/2/2022
    The novel and recurrent variants in exon 31 of CREBBP in Japanese patients with Menke-Hennekam syndrome.

    The novel and recurrent variants in exon 31 of CREBBP in Japanese patients with Menke-Hennekam syndrome.
    Nishi E, Takenouchi T, Miya F, Uehara T, Yanagi K, Hasegawa Y, Ueda K, Mizuno S, Kaname T, Kosaki K, Okamoto N.

    04/16/2022
    Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.

    Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.
    Kongkiatkamon S, Pagliuca S, Adema V, Nagata Y, Kerr CM, Walter W, Awada H, Hutter S, Gurnari C, Rogers HJ, Meggendorfer M, Saunthararajah Y, Haferlach T, Visconte V, Maciejewski JP.

    04/16/2022
    Urinary Sediment mRNA Level of CREBBP and CYBA in Children With Steroid-Resistant Nephrotic Syndrome.

    Urinary Sediment mRNA Level of CREBBP and CYBA in Children With Steroid-Resistant Nephrotic Syndrome.
    Li W, Shou X, Xiang W, He L, Li L, Fu H, Mao J., Free PMC Article

    03/12/2022
    Individual functions of the histone acetyl transferases CBP and p300 in regulating the inflammatory response of synovial fibroblasts.

    Individual functions of the histone acetyl transferases CBP and p300 in regulating the inflammatory response of synovial fibroblasts.
    Krošel M, Gabathuler M, Maciukiewicz M, Moser L, Lee GI, Marks M, Tomšič M, Distler O, Ospelt C, Klein K.

    02/26/2022
    Age influences on the molecular presentation of tumours.

    Age influences on the molecular presentation of tumours.
    Li CH, Haider S, Boutros PC., Free PMC Article

    02/12/2022
    Upregulation of alpha enolase (ENO1) crotonylation in colorectal cancer and its promoting effect on cancer cell metastasis.

    Upregulation of α enolase (ENO1) crotonylation in colorectal cancer and its promoting effect on cancer cell metastasis.
    Hou JY, Cao J, Gao LJ, Zhang FP, Shen J, Zhou L, Shi JY, Feng YL, Yan Z, Wang DP, Cao JM.

    01/29/2022
    PP-1beta and PP-2Aalpha modulate cAMP response element-binding protein (CREB) functions in aging control and stress response through de-regulation of alphaB-crystallin gene and p300-p53 signaling axis.

    PP-1β and PP-2Aα modulate cAMP response element-binding protein (CREB) functions in aging control and stress response through de-regulation of αB-crystallin gene and p300-p53 signaling axis.
    Wang L, Zhang L, Gong XD, Fu JL, Gan YW, Hou M, Nie Q, Xiang JW, Xiao Y, Wang Y, Zheng SY, Yang L, Chen H, Xiang MQ, Liu Y, Li DW., Free PMC Article

    01/29/2022
    A Novel Intronic Circular RNA Antagonizes Influenza Virus by Absorbing a microRNA That Degrades CREBBP and Accelerating IFN-beta Production.

    A Novel Intronic Circular RNA Antagonizes Influenza Virus by Absorbing a microRNA That Degrades CREBBP and Accelerating IFN-β Production.
    Qu Z, Meng F, Shi J, Deng G, Zeng X, Ge J, Li Y, Liu L, Chen P, Jiang Y, Li C, Chen H., Free PMC Article

    12/25/2021
    Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function.

    Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function.
    Kumar M, Molkentine D, Molkentine J, Bridges K, Xie T, Yang L, Hefner A, Gao M, Bahri R, Dhawan A, Frederick MJ, Seth S, Abdelhakiem M, Beadle BM, Johnson F, Wang J, Shen L, Heffernan T, Sheth A, Ferris RL, Myers JN, Pickering CR, Skinner HD., Free PMC Article

    12/11/2021
    CBP-mediated Slug acetylation stabilizes Slug and promotes EMT and migration of breast cancer cells.

    CBP-mediated Slug acetylation stabilizes Slug and promotes EMT and migration of breast cancer cells.
    Dai X, Xin Y, Xu W, Tian X, Wei X, Zhang H.

    12/11/2021
    EP300/CBP is crucial for cAMP-PKA pathway to alleviate podocyte dedifferentiation via targeting Notch3 signaling.

    EP300/CBP is crucial for cAMP-PKA pathway to alleviate podocyte dedifferentiation via targeting Notch3 signaling.
    Chang K, Xue R, Zhao M, Zhao Y, Yu W, Zhao Z, Liu X.

    11/27/2021
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