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    ATF2 activating transcription factor 2 [ Homo sapiens (human) ]

    Gene ID: 1386, updated on 14-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    MAP4K4 and WT1 mediate SOX6-induced cellular senescence by synergistically activating the ATF2-TGFbeta2-Smad2/3 signaling pathway in cervical cancer.

    MAP4K4 and WT1 mediate SOX6-induced cellular senescence by synergistically activating the ATF2-TGFβ2-Smad2/3 signaling pathway in cervical cancer.
    Zheng H, Liu M, Shi S, Huang H, Yang X, Luo Z, Song Y, Xu Q, Li T, Xue L, Lu F, Wang J., Free PMC Article

    05/9/2024
    Human umbilical cord mesenchymal stem cell-derived exosomes loaded miR-451a targets ATF2 to improve rheumatoid arthritis.

    Human umbilical cord mesenchymal stem cell-derived exosomes loaded miR-451a targets ATF2 to improve rheumatoid arthritis.
    Mi L, Gao J, Li N, Liu Y, Zhang N, Gao Y, Peng X, Zhang L, Xu K.

    01/29/2024
    The ATF2/miR-3913-5p/CREB5 axis is involved in the cell proliferation and metastasis of colorectal cancer.

    The ATF2/miR-3913-5p/CREB5 axis is involved in the cell proliferation and metastasis of colorectal cancer.
    Dai W, Hong L, Xiao W, Zhang L, Sha W, Yu Z, Liu X, Liu S, Xiao Y, Yang P, Peng Y, Zhang J, Lin J, Wu X, Tang W, Lin Z, Xiang L, Li J, Pei M, Wang J., Free PMC Article

    11/2/2023
    USP14 Regulates ATF2/PIK3CD Axis to Promote Microvascular Endothelial Cell Proliferation, Migration, and Angiogenesis in Diabetic Retinopathy.

    USP14 Regulates ATF2/PIK3CD Axis to Promote Microvascular Endothelial Cell Proliferation, Migration, and Angiogenesis in Diabetic Retinopathy.
    He FT, Fu XL, Li MH, Fu CY, Chen JZ.

    11/1/2023
    Analysis of the interaction of a non-canonical twin half-site of Cyclic AMP-Response Element (CRE) with CRE-binding protein.

    Analysis of the interaction of a non-canonical twin half-site of Cyclic AMP-Response Element (CRE) with CRE-binding protein.
    Mukherjee S, Sarkar AK, Lahiri A, Sengupta Bandyopadhyay S.

    10/20/2023
    The transcription factor ATF2 promotes gastric cancer progression by activating the METTL3/cyclin D1 pathway.

    The transcription factor ATF2 promotes gastric cancer progression by activating the METTL3/cyclin D1 pathway.
    Meng H, Li J, Sun H, Lin Y, Xu H, Zhang N.

    09/18/2023
    ATF2 orchestrates macrophage differentiation and activation to promote antibacterial responses.

    ATF2 orchestrates macrophage differentiation and activation to promote antibacterial responses.
    Rajabalee N, Siushansian H, Weerapura M, Berton S, Berbatovci F, Hooks B, Geoffrion M, Yang D, Harper ME, Rayner K, Blais A, Sun J.

    09/6/2023
    ATF2 loss promotes 5-FU resistance in colon cancer cells via activation of the ATR-Chk1 damage response pathway.

    ATF2 loss promotes 5-FU resistance in colon cancer cells via activation of the ATR-Chk1 damage response pathway.
    Yang H, Huebner K, Hampel C, Erlenbach-Wuensch K, Selvamani SB, Shukla V, Geppert CI, Hartmann A, Mahadevan V, Schneider-Stock R., Free PMC Article

    06/2/2023
    Activating transcription factor-2 supports the antioxidant capacity and ability of human mesenchymal stem cells to prevent asthmatic airway inflammation.

    Activating transcription factor-2 supports the antioxidant capacity and ability of human mesenchymal stem cells to prevent asthmatic airway inflammation.
    Ju H, Yun H, Kim Y, Nam YJ, Lee S, Lee J, Jeong SM, Heo J, Kwon H, Cho YS, Jeong G, Ryu CM, Shin DM., Free PMC Article

    03/10/2023
    Increased ATF2 expression predicts poor prognosis and inhibits sorafenib-induced ferroptosis in gastric cancer.

    Increased ATF2 expression predicts poor prognosis and inhibits sorafenib-induced ferroptosis in gastric cancer.
    Xu X, Li Y, Wu Y, Wang M, Lu Y, Fang Z, Wang H, Li Y., Free PMC Article

    01/21/2023
    ATF2 loss promotes tumor invasion in colorectal cancer cells via upregulation of cancer driver TROP2.

    ATF2 loss promotes tumor invasion in colorectal cancer cells via upregulation of cancer driver TROP2.
    Huebner K, Erlenbach-Wuensch K, Prochazka J, Sheraj I, Hampel C, Mrazkova B, Michalcikova T, Tureckova J, Iatsiuk V, Weissmann A, Ferrazzi F, Kunze P, Nalli E, Sammer E, Gehring A, Cheema MM, Eckstein M, Paap EM, Soederberg A, Fischer C, Paul S, Mahadevan V, Ndreshkjana B, Meier MA, Muehlich S, Geppert CI, Merkel S, Grutzmann R, Roehe A, Banerjee S, Hartmann A, Sedlacek R, Schneider-Stock R., Free PMC Article

    08/6/2022
    lncRNA PINK1-AS Aggravates Cerebral Ischemia/Reperfusion Oxidative Stress Injury through Regulating ATF2 by Sponging miR-203.

    lncRNA PINK1-AS Aggravates Cerebral Ischemia/Reperfusion Oxidative Stress Injury through Regulating ATF2 by Sponging miR-203.
    Yang ZB, Xiang Y, Zuo ML, Mao L, Hu GH, Song GL, Sheikh MSA, Tan LM., Free PMC Article

    07/30/2022
    Activating transcription factor 2 promotes the progression of hepatocellular carcinoma by inducing the activation of the WHSC1-mediated TOP2A/PI3K/AKT axis.

    Activating transcription factor 2 promotes the progression of hepatocellular carcinoma by inducing the activation of the WHSC1-mediated TOP2A/PI3K/AKT axis.
    Bao ZM, Yao D, Qian X, Zhang HG, Yang M, Guo YH, Qin L.

    07/16/2022
    Protein disulfide-isomerase A3 knockdown attenuates oxidized low-density lipoprotein-induced oxidative stress, inflammation and endothelial dysfunction in human umbilical vein endothelial cells by downregulating activating transcription factor 2.

    Protein disulfide-isomerase A3 knockdown attenuates oxidized low-density lipoprotein-induced oxidative stress, inflammation and endothelial dysfunction in human umbilical vein endothelial cells by downregulating activating transcription factor 2.
    Jia J, Wang Y, Huang R, Du F, Shen X, Yang Q, Li J., Free PMC Article

    02/26/2022
    Long noncoding RNA ZSCAN16AS1 promotes the malignant properties of hepatocellular carcinoma by decoying microRNA451a and consequently increasing ATF2 expression.

    Long non‑coding RNA ZSCAN16‑AS1 promotes the malignant properties of hepatocellular carcinoma by decoying microRNA‑451a and consequently increasing ATF2 expression.
    Lv C, Wan Q, Shen C, Wu H, Zhou B, Wang W., Free PMC Article

    02/12/2022
    Long Noncoding RNA RP11-357H14.17 Plays an Oncogene Role in Gastric Cancer by Activating ATF2 Signaling and Enhancing Treg Cells.

    Long Noncoding RNA RP11-357H14.17 Plays an Oncogene Role in Gastric Cancer by Activating ATF2 Signaling and Enhancing Treg Cells.
    Xiaoli T, Wenting W, Meixiang Z, Chunlei Z, Chengxia H., Free PMC Article

    10/30/2021
    Aberration of the modulatory functions of intronic microRNA hsa-miR-933 on its host gene ATF2 results in type II diabetes mellitus and neurodegenerative disease development.

    Aberration of the modulatory functions of intronic microRNA hsa-miR-933 on its host gene ATF2 results in type II diabetes mellitus and neurodegenerative disease development.
    Islam ABMMK, Mohammad E, Khan MA., Free PMC Article

    10/23/2021
    MARCH6 promotes hepatocellular carcinoma development through up-regulation of ATF2.

    MARCH6 promotes hepatocellular carcinoma development through up-regulation of ATF2.
    Sun J, Dong Z, Chang Z, Liu H, Jiang Q, Zhang D, Lu S, Jia X, Wu D, Ge A, Zhao P, Wang J, Lu Y., Free PMC Article

    10/16/2021
    Sprouty2 Inhibits Migration and Invasion of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis by Down-regulating ATF2 Expression and Phosphorylation.

    Sprouty2 Inhibits Migration and Invasion of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis by Down-regulating ATF2 Expression and Phosphorylation.
    Zhang X, Zhang D, Wang Q, Guo X, Chen J, Jiang J, Li M, Liu W, Gao Y, Zhang Q, Bao G, Cui Z.

    10/9/2021
    KIF18B promotes tumor progression in osteosarcoma by activating beta-catenin.

    KIF18B promotes tumor progression in osteosarcoma by activating β-catenin.
    Gao T, Yu L, Fang Z, Liu J, Bai C, Li S, Xue R, Zhang L, Tan Z, Fan Z., Free PMC Article

    10/9/2021
    Protective effect of SIRT6 on cholesterol crystal-induced endothelial dysfunction via regulating ACE2 expression.

    Protective effect of SIRT6 on cholesterol crystal-induced endothelial dysfunction via regulating ACE2 expression.
    Zheng Z, Wang B, Lv X, Yao F, Gao H, Jin Z, Liu Y, Deng Y, Chen D, Ning X, Wang W, He J, Lin R.

    09/25/2021
    Activating transcription factor-2 (ATF2) is a key determinant of resistance to endocrine treatment in an in vitro model of breast cancer.

    Activating transcription factor-2 (ATF2) is a key determinant of resistance to endocrine treatment in an in vitro model of breast cancer.
    Giannoudis A, Malki MI, Rudraraju B, Mohhamed H, Menon S, Liloglou T, Ali S, Carroll JS, Palmieri C., Free PMC Article

    06/26/2021
    Micro-RNA-451 Reduces Proliferation of B-CPAP Human Papillary Thyroid Cancer Cells by Downregulating Expression of Activating Transcription Factor 2.

    Micro-RNA-451 Reduces Proliferation of B-CPAP Human Papillary Thyroid Cancer Cells by Downregulating Expression of Activating Transcription Factor 2.
    Zhang MF, Fei ZW, Huang L., Free PMC Article

    05/29/2021
    Exosomal microRNA-26b-5p down-regulates ATF2 to enhance radiosensitivity of lung adenocarcinoma cells.

    Exosomal microRNA-26b-5p down-regulates ATF2 to enhance radiosensitivity of lung adenocarcinoma cells.
    Han F, Huang D, Huang X, Wang W, Yang S, Chen S., Free PMC Article

    05/15/2021
    Mechano growth factor pretreatment yield mechanical stimuli induced cell stress responses in ligament fibroblasts of osteoarthritis via activating ATF-2.

    Mechano growth factor pretreatment yield mechanical stimuli induced cell stress responses in ligament fibroblasts of osteoarthritis via activating ATF-2.
    Ma Y, Song Y, Li L, Dong L, Wang C, Wang P, Yang L.

    02/13/2021
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