| The role of EphA7 in different tumors. | The role of EphA7 in different tumors.
Chen X, Yu D, Zhou H, Zhang X, Hu Y, Zhang R, Gao X, Lin M, Guo T, Zhang K. | 06/18/2022 |
| Satb2 Regulates EphA7 to Control Soma Spacing and Self-Avoidance of Cortical Pyramidal Neurons. | Satb2 Regulates EphA7 to Control Soma Spacing and Self-Avoidance of Cortical Pyramidal Neurons.
He CH, Zhang L, Song NN, Mei WY, Chen JY, Hu L, Zhang Q, Wang YB, Ding YQ. | 06/11/2022 |
| Zfp422 promotes skeletal muscle differentiation by regulating EphA7 to induce appropriate myoblast apoptosis. | Zfp422 promotes skeletal muscle differentiation by regulating EphA7 to induce appropriate myoblast apoptosis.
Nie Y, Cai S, Yuan R, Ding S, Zhang X, Chen L, Chen Y, Mo D., Free PMC Article | 07/3/2021 |
| EphA7 promotes myogenic differentiation via cell-cell contact. | EphA7 promotes myogenic differentiation via cell-cell contact.
Arnold LL, Cecchini A, Stark DA, Ihnat J, Craigg RN, Carter A, Zino S, Cornelison D., Free PMC Article | 04/3/2021 |
| Data suggest BMI1 overexpression as a novel mechanism leading to EphA7 inactivation via H3K27 trimethylation and DNA methylation by which BMI-1 controls cell proliferation in the postnatal lateral ventricle wall. | The putative tumor suppressor gene EphA7 is a novel BMI-1 target.
Prost G, Braun S, Hertwig F, Winkler M, Jagemann L, Nolbrant S, Leefa IV, Offen N, Miharada K, Lang S, Artner I, Nuber UA., Free PMC Article | 02/24/2018 |
| The present study demonstrates that EphA7 receptors, despite their similar structure, have distinct in vivo effects on corticothalamic system projections into the ventrobasal complex /medial division of the posterior nuclear group. | EphA4 has distinct functionality from EphA7 in the corticothalamic system during mouse brain development.
Son AI, Hashimoto-Torii K, Rakic P, Levitt P, Torii M., Free PMC Article | 09/2/2017 |
| Results suggest that EphA7 plays an important role in the developmental formation of cochlear innervation pattern through controlling spiral ganglion neuron fiber ontogeny | EphA7 regulates spiral ganglion innervation of cochlear hair cells.
Kim YJ, Ibrahim LA, Wang SZ, Yuan W, Evgrafov OV, Knowles JA, Wang K, Tao HW, Zhang LI., Free PMC Article | 12/17/2016 |
| Truncated EPHA7 promotes cell reprogramming by inducing ERK activity reduction. | Secreted Ephrin Receptor A7 Promotes Somatic Cell Reprogramming by Inducing ERK Activity Reduction.
Lee J, Nakajima-Koyama M, Sone M, Koga M, Ebisuya M, Yamamoto T, Nishida E., Free PMC Article | 08/6/2016 |
| Data show the effects of genetic loss of ephrin-A5, Eph receptors EphA4, and EphA7 on the development of medulloblastoma tumors in the smoothened (Smo) transgenic mouse model. | Effects of altered ephrin-A5 and EphA4/EphA7 expression on tumor growth in a medulloblastoma mouse model.
Bhatia S, Hirsch K, Baig NA, Rodriguez O, Timofeeva O, Kavanagh K, Lee YC, Wang XJ, Albanese C, Karam SD., Free PMC Article | 07/16/2016 |
| Results support the hypothesis that the anatomical organization of striatal and thalamic neurons expressing EphA7 receptors restricts the topographic distribution of cortical afferents from medial regions of S1 which express high levels of ephrin-A5 | Corticofugal projections from medial primary somatosensory cortex avoid EphA7-expressing neurons in striatum and thalamus.
Tai AX, Kromer LF. | 10/17/2015 |
| EphA4/EphA7 from the pericloacal mesenchyme signal via ephrin B2 to mediate nephric duct insertion. | Nephric duct insertion requires EphA4/EphA7 signaling from the pericloacal mesenchyme.
Weiss AC, Airik R, Bohnenpoll T, Greulich F, Foik A, Trowe MO, Rudat C, Costantini F, Adams RH, Kispert A. | 10/18/2014 |
| The role of cell-based signaling via the receptor tyrosine kinase EphA7 in guiding the extension and maturation of cortical dendrites, was examined. | EphA7 signaling guides cortical dendritic development and spine maturation.
Clifford MA, Athar W, Leonard CE, Russo A, Sampognaro PJ, Van der Goes MS, Burton DA, Zhao X, Lalchandani RR, Sahin M, Vicini S, Donoghue MJ., Free PMC Article | 06/7/2014 |
| multi-protein complex comprising ephrinA5, EphA7, and TNFR1 may constitute a platform for inducing caspase-dependent apoptotic | EphrinA5-EphA7 complex induces apoptotic cell death via TNFR1.
Lee H, Park E, Kim Y, Park S., Free PMC Article | 02/1/2014 |
| Data show that Dlx5 and Msx2 play a critical role in controlling cranial neural tube morphogenesis by regulating cell adhesion via the ephrinA5 and EphA7 pathway. | Dlx5 and Msx2 regulate mouse anterior neural tube closure through ephrinA5-EphA7.
Lee J, Corcoran A, Han M, Gardiner DM, Muneoka K. | 10/19/2013 |
| This study demonstrated a potential role for EphA/ephrin-A signaling in the initial guidance of corticofugal axons. | EphA signaling impacts development of topographic connectivity in auditory corticofugal systems.
Torii M, Hackett TA, Rakic P, Levitt P, Polley DB., Free PMC Article | 09/28/2013 |
| We used in utero electroporation-mediated EphA7 overexpression in developing somatosensory CT axons to dissect EphA7/ephrin-A-dependent mechanisms involved in regulating both initial targeting and postnatal growth of the corticothalamic projections. | Role of EphA/ephrin--a signaling in the development of topographic maps in mouse corticothalamic projections.
Torii M, Rakic P, Levitt P., Free PMC Article | 06/8/2013 |
| Our study identifies a novel repertoire of cortical neuron genes that may act upstream of, or together with EphA7, to control the patterning of cortical areas. | Transcriptional mechanisms of EphA7 gene expression in the developing cerebral cortex.
Pietri S, Dimidschstein J, Tiberi L, Sotiropoulou PA, Bilheu A, Goffinet A, Achouri Y, Tissir F, Blanpain C, Jacquemin P, Vanderhaeghen P. | 11/17/2012 |
| Study identified EPHA7 as a tumor suppressor that is shed from germinal center B cells and lost in follicular lymphoma. | The Eph-receptor A7 is a soluble tumor suppressor for follicular lymphoma.
Oricchio E, Nanjangud G, Wolfe AL, Schatz JH, Mavrakis KJ, Jiang M, Liu X, Bruno J, Heguy A, Olshen AB, Socci ND, Teruya-Feldstein J, Weis-Garcia F, Tam W, Shaknovich R, Melnick A, Himanen JP, Chaganti RS, Wendel HG., Free PMC Article | 12/24/2011 |
| The dorsal midline-specific EphA7 enhancer resides on the 457D20 EphA7 BAC clone and is localized to a 35 kb genomic region in between +345.7 kb to +379.8 kb downstream of the EphA7 transcription start site. | Identification of EphA7 BAC clone containing a long-range dorsal midline-specific enhancer.
Kim Y, Park S. | 06/18/2011 |
| ephrin-A/EphA receptor signalling plays a key role in controlling the size of the mouse cerebral cortex by regulating cortical progenitor cell apoptosis | Ephrin signalling controls brain size by regulating apoptosis of neural progenitors.
Depaepe V, Suarez-Gonzalez N, Dufour A, Passante L, Gorski JA, Jones KR, Ledent C, Vanderhaeghen P. | 01/21/2010 |
| EphA7 is a direct downstream target of Hoxd13 and Hoxa13 during limb development | Hoxd13 and Hoxa13 directly control the expression of the EphA7 Ephrin tyrosine kinase receptor in developing limbs.
Salsi V, Zappavigna V. | 01/21/2010 |
| Neocortical expression of Epha7 during development remains stable in the absence of cellular contacts and thalamocortical connections. | EphA family gene expression in the developing mouse neocortex: regional patterns reveal intrinsic programs and extrinsic influence.
Yun ME, Johnson RR, Antic A, Donoghue MJ. | 01/21/2010 |
| HOXA13 directly regulates EphA6 and EphA7 in the developing genital tubercle. | HOXA13 directly regulates EphA6 and EphA7 expression in the genital tubercle vascular endothelia.
Shaut CA, Saneyoshi C, Morgan EA, Knosp WM, Sexton DR, Stadler HS. | 01/21/2010 |
| EphA7-mediated signaling on neocortical axons controls the within-nucleus topography of corticothalamic projections in the thalamus. (EphA7) | Dissociation of corticothalamic and thalamocortical axon targeting by an EphA7-mediated mechanism.
Torii M, Levitt P. | 01/21/2010 |