| Expression of Interferon Epsilon in Mucosal Epithelium is Regulated by Elf3. | Expression of Interferon Epsilon in Mucosal Epithelium is Regulated by Elf3.
Fung KY, de Geus ED, Ying L, Cumming H, Bourke N, Foster SC, Hertzog PJ., | 08/14/2024 |
| ESE-1 mediates lipopolysaccharide-induced BV2 cell inflammation via upregulation of HMGB1 expression. | ESE-1 mediates lipopolysaccharide-induced BV2 cell inflammation via upregulation of HMGB1 expression.
Lu Y, Ding J, Huang J, Zhao Y. | 11/15/2023 |
| ELF3 promotes gemcitabine resistance through PKMYT1/CDK1 signaling pathway in gallbladder cancer. | ELF3 promotes gemcitabine resistance through PKMYT1/CDK1 signaling pathway in gallbladder cancer.
Yang L, Wang H, Guo M, He M, Zhang W, Zhan M, Liu Y. | 07/21/2023 |
| E74 Like ETS Transcription Factor 3 is a Negative Regulator of Pathogenic Lamina Propria T Helper 17.1 Cells in Murine Colitis. | E74 Like ETS Transcription Factor 3 is a Negative Regulator of Pathogenic Lamina Propria T Helper 17.1 Cells in Murine Colitis.
Hu B, Wang H, Xiao F. | 10/8/2022 |
| Bone marrow mesenchymal stem cell-derived exosomal miR-206 promotes osteoblast proliferation and differentiation in osteoarthritis by reducing Elf3. | Bone marrow mesenchymal stem cell-derived exosomal miR-206 promotes osteoblast proliferation and differentiation in osteoarthritis by reducing Elf3.
Huang Y, Zhang X, Zhan J, Yan Z, Chen D, Xue X, Pan X., Free PMC Article | 02/19/2022 |
| ELF3 is an oncogene in lung adenocarcinoma. ELF3 signaling networks are highly tissue-specific, accounting for its conflicting functions across epithelial cancers. | Epithelial tumor suppressor ELF3 is a lineage-specific amplified oncogene in lung adenocarcinoma.
Enfield KSS, Marshall EA, Anderson C, Ng KW, Rahmati S, Xu Z, Fuller M, Milne K, Lu D, Shi R, Rowbotham DA, Becker-Santos DD, Johnson FD, English JC, MacAulay CE, Lam S, Lockwood WW, Chari R, Karsan A, Jurisica I, Lam WL., Free PMC Article | 03/7/2020 |
| The rate of decline in the estimated Glomerular Filtration Rate (eGFR) after measurement of urinary exosomal Elf3 protein levels in patients with Diabetic nephropathy (DN) (R2 = 0.7259) might be useful as an early non-invasive marker for podocyte injuries in DN. | Involvement of Elf3 on Smad3 activation-dependent injuries in podocytes and excretion of urinary exosome in diabetic nephropathy.
Sakurai A, Ono H, Ochi A, Matsuura M, Yoshimoto S, Kishi S, Murakami T, Tominaga T, Nagai K, Abe H, Doi T., Free PMC Article | 01/25/2020 |
| ELF3 controls LCN2 expression in cooperation with NFkappaB. | E74-like factor 3 and nuclear factor-κB regulate lipocalin-2 expression in chondrocytes.
Conde J, Otero M, Scotece M, Abella V, López V, Pino J, Gómez R, Lago F, Goldring MB, Gualillo O., Free PMC Article | 09/2/2017 |
| a novel role for ELF3 as a procatabolic factor that may contribute to cartilage remodeling and degradation by regulating MMP13 gene transcription. | E74-like factor 3 (ELF3) impacts on matrix metalloproteinase 13 (MMP13) transcriptional control in articular chondrocytes under proinflammatory stress.
Otero M, Plumb DA, Tsuchimochi K, Dragomir CL, Hashimoto K, Peng H, Olivotto E, Bevilacqua M, Tan L, Yang Z, Zhan Y, Oettgen P, Li Y, Marcu KB, Goldring MB., Free PMC Article | 03/24/2012 |
| A novel function of Elf3 is identified that defines allergic airway inflammation caused by the regulation of dendritic cell-driven T helper (Th)1 cell, Th2 cell, and Th17 cell differentiation. | Elf3 regulates allergic airway inflammation by controlling dendritic cell-driven T cell differentiation.
Kushwah R, Oliver JR, Wu J, Chang Z, Hu J. | 01/28/2012 |
| Elf3 plays an important role in the regulation of lung cell proliferation and differentiation during repair of the injured bronchiolar airway epithelium. | Elf3 plays a role in regulating bronchiolar epithelial repair kinetics following Clara cell-specific injury.
Oliver JR, Kushwah R, Wu J, Pan J, Cutz E, Yeger H, Waddell TK, Hu J. | 11/26/2011 |
| ESE-1 is an Ang II-inducible transcription factor that plays an important counter-regulatory role in the setting of vascular inflammation and remodeling. | The counter-regulatory effects of ESE-1 during angiotensin II-mediated vascular inflammation and remodeling.
Zhan Y, Yuan L, Kondo M, Oettgen P., Free PMC Article | 03/5/2011 |
| Elf3 amino acid residues within the flanking region, including Trp361, are important for the structural integrity of the protein as well as for the Efl3 DNA binding and transactivation activity. | Crystal structure of mouse Elf3 C-terminal DNA-binding domain in complex with type II TGF-beta receptor promoter DNA.
Agarkar VB, Babayeva ND, Wilder PJ, Rizzino A, Tahirov TH., Free PMC Article | 04/12/2010 |
| Like other Ets-family members, Elf3 functions as a sequence-specific DNA-binding transcriptional factor | Preliminary crystallographic analysis of mouse Elf3 C-terminal DNA-binding domain in complex with type II TGF-beta receptor promoter DNA.
Agarkar VB, Babayeva ND, Rizzino A, Tahirov TH., Free PMC Article | 03/22/2010 |
| Results reveal that Crif1 is a novel and essential transcriptional coactivator of Elf3 for the terminal differentiation of absorptive enterocytes. | Essential role of CR6-interacting factor 1 (Crif1) in E74-like factor 3 (ELF3)-mediated intestinal development.
Kwon MC, Koo BK, Kim YY, Lee SH, Kim NS, Kim JH, Kong YY., Free PMC Article | 01/25/2010 |
| ErbB2 activation of ESX gene expression | ErbB2 activation of ESX gene expression.
Neve RM, Ylstra B, Chang CH, Albertson DG, Benz CC. | 01/21/2010 |
| Elf3 contains multiple NLS motifs, which may function cooperatively to effect efficient nuclear transport | Identification of multiple nuclear localization signals in murine Elf3, an ETS transcription factor.
Do HJ, Song H, Yang HM, Kim DK, Kim NH, Kim JH, Cha KY, Chung HM, Kim JH. | 01/21/2010 |
| Evidence that mElf-3, a member of the Ets family, plays a key role in the activation of the mTbetaR-II promoter. | Activation of the murine type II transforming growth factor-beta receptor gene: up-regulation and function of the transcription factor Elf-3/Ert/Esx/Ese-1.
Kim JH, Wilder PJ, Hou J, Nowling T, Rizzino A. | 01/21/2010 |
| Both proximal and distal regions that regulate Elf3 promoter activity were identified. | Transcriptional regulation of the murine Elf3 gene in embryonal carcinoma cells and their differentiated counterparts: requirement for a novel upstream regulatory region.
Hou J, Wilder PJ, Bernadt CT, Boer B, Neve RM, Rizzino A. | 01/21/2010 |