| Hypoxia-inducible microRNA-155 negatively regulates epithelial barrier in eosinophilic esophagitis by suppressing tight junction claudin-7. | Hypoxia-inducible microRNA-155 negatively regulates epithelial barrier in eosinophilic esophagitis by suppressing tight junction claudin-7.
Markey GE, Ryan S, Furuta GT, Menard-Katcher C, McNamee EN, Masterson JC., | 12/6/2023 |
| Matrix metalloproteinase 7 contributes to intestinal barrier dysfunction by degrading tight junction protein Claudin-7. | Matrix metalloproteinase 7 contributes to intestinal barrier dysfunction by degrading tight junction protein Claudin-7.
Xiao Y, Lian H, Zhong XS, Krishnachaitanya SS, Cong Y, Dashwood RH, Savidge TC, Powell DW, Liu X, Li Q., Free PMC Article | 10/29/2022 |
| Claudin-7 in keratinocytes is downregulated by the inhibition of HMG-CoA reductase and is highly expressed in the stratum granulosum of the psoriatic epidermis. | Claudin-7 in keratinocytes is downregulated by the inhibition of HMG-CoA reductase and is highly expressed in the stratum granulosum of the psoriatic epidermis.
Kuwatsuka S, Koike Y, Kuwatsuka Y, Yamaoka T, Murota H. | 02/26/2022 |
| N-glycosylation status of Trop2 impacts its surface density, interaction with claudin-7 and exosomal release. | N-glycosylation status of Trop2 impacts its surface density, interaction with claudin-7 and exosomal release.
Kamble PR, Patkar SR, Breed AA, Pathak BR. | 12/11/2021 |
| A Claudin-Based Molecular Signature Identifies High-Risk, Chemoresistant Colorectal Cancer Patients. | A Claudin-Based Molecular Signature Identifies High-Risk, Chemoresistant Colorectal Cancer Patients.
Gowrikumar S, Primeaux M, Pravoverov K, Wu C, Szeglin BC, Sauvé CG, Thapa I, Bastola D, Chen XS, Smith JJ, Singh AB, Dhawan P., Free PMC Article | 11/22/2021 |
| Claudin-7 deficiency promotes stemness properties in colorectal cancer through Sox9-mediated Wnt/beta-catenin signalling. | Claudin-7 deficiency promotes stemness properties in colorectal cancer through Sox9-mediated Wnt/β-catenin signalling.
Xu C, Ding YH, Wang K, Hao M, Li H, Ding L., Free PMC Article | 09/18/2021 |
| Reduced occludin and claudin-7 expression is associated with urban locations and exposure to second-hand smoke in allergic rhinitis patients. | Reduced occludin and claudin-7 expression is associated with urban locations and exposure to second-hand smoke in allergic rhinitis patients.
Nur Husna SM, Siti Sarah CO, Tan HT, Md Shukri N, Mohd Ashari NS, Wong KK., Free PMC Article | 08/14/2021 |
| The p53-inducible CLDN7 regulates colorectal tumorigenesis and has prognostic significance. | The p53-inducible CLDN7 regulates colorectal tumorigenesis and has prognostic significance.
Hou Y, Hou L, Liang Y, Zhang Q, Hong X, Wang Y, Huang X, Zhong T, Pang W, Xu C, Zhu L, Li L, Fang J, Meng X., Free PMC Article | 07/31/2021 |
| Claudin-7 Inhibits Proliferation and Metastasis in Salivary Adenoid Cystic Carcinoma Through Wnt/beta-Catenin Signaling. | Claudin-7 Inhibits Proliferation and Metastasis in Salivary Adenoid Cystic Carcinoma Through Wnt/β-Catenin Signaling.
Ji H, Ding X, Zhang W, Zheng Y, Du H, Zheng Y, Song H, Li M, Jiang Y, Xie J, Wu M, Jiao P, Wang Z, Wu H, Zhong Y., Free PMC Article | 07/24/2021 |
| Titanium dioxide particles modulate epithelial barrier protein, Claudin 7 in asthma. | Titanium dioxide particles modulate epithelial barrier protein, Claudin 7 in asthma.
Lee YG, Lee SH, Hong J, Lee PH, Jang AS. | 04/24/2021 |
| Long noncoding RNA DDX11-AS1 induced by YY1 accelerates colorectal cancer progression through targeting miR-873/CLDN7 axis. | Long noncoding RNA DDX11-AS1 induced by YY1 accelerates colorectal cancer progression through targeting miR-873/CLDN7 axis.
Tian JB, Cao L, Dong GL. | 10/3/2020 |
| Claudin-7 is frequently expressed in the chromophobe renal cell carcinoma with high specificity. | Combined Immunohistochemistry for the "Three 7" Markers (CK7, CD117, and Claudin-7) Is Useful in the Diagnosis of Chromophobe Renal Cell Carcinoma and for the Exclusion of Mimics: Diagnostic Experience from a Single Institution.
Zhou J, Yang X, Zhou L, Zhang P, Wang C., Free PMC Article | 05/2/2020 |
| Results how that cancer-initiating cell (CIC) -tumor exosomes (TEX) rescue Claudin7 (cld7)-knockdown (kd) (cld7kd) tumor progression. | Claudin7-dependent exosome-promoted reprogramming of nonmetastasizing tumor cells.
Kyuno D, Zhao K, Schnölzer M, Provaznik J, Hackert T, Zöller M. | 02/8/2020 |
| the findings of the present study demonstrated that the expression levels of CLDN1, 3, 7 and 8 varied between laryngeal squamous carcinoma tissues and nonneoplastic tissues | Identification of claudin‑1, ‑3, ‑7 and ‑8 as prognostic markers in human laryngeal carcinoma.
Zhou S, Piao X, Wang C, Wang R, Song Z., Free PMC Article | 11/30/2019 |
| Decreasing expression of Claudin-7 may promote the invasion and metastasis of colorectal cancer by regulating epithelial-mesenchymal transition. | Claudin-7 downregulation induces metastasis and invasion in colorectal cancer via the promotion of epithelial-mesenchymal transition.
Wang K, Li T, Xu C, Ding Y, Li W, Ding L. | 09/21/2019 |
| In the salivary gland ducts from patients with IgG4-related disease there was significant infiltration of IgG-positive plasma cells, and expression of GBP-1, CLDN-7 and LSR was increased. | Guanylate binding protein-1-mediated epithelial barrier in human salivary gland duct epithelium.
Konno T, Takano K, Kaneko Y, Kakuki T, Nomura K, Yajima R, Kakiuchi A, Kohno T, Himi T, Kojima T. | 09/21/2019 |
| CLDN7 expression is significantly elevated in gastric cancer tissues, and the overexpression of CLDN7 is closely related to lymph node metastasis. CLDN7 executes an oncogenic function, promoting cancer cell proliferation, invasion, and epithelial-mesenchymal transition. | Claudin-7 (CLDN7) is overexpressed in gastric cancer and promotes gastric cancer cell proliferation, invasion and maintains mesenchymal state.
Wu Z, Shi J, Song Y, Zhao J, Sun J, Chen X, Gao P, Wang Z. | 06/29/2019 |
| CLDN7 may be expressed in the rapidly proliferating and dominant cell population in human pancreatic cancer tissues. | Claudin 7 as a possible novel molecular target for the treatment of pancreatic cancer.
Okui N, Kamata Y, Sagawa Y, Kuhara A, Hayashi K, Uwagawa T, Homma S, Yanaga K. | 04/27/2019 |
| The mechanism involved in the modulation of serine phosphorylated claudin-7. | The effect of serine phosphorylated claudin-7 on the epithelial barrier and the modulation by transient receptor potential vanilloid 4 in human colonic cells.
Huang YY, Wang ZK, Li J, Bai SW, Shen B, Du J, Xia XM, Wang FY. | 03/2/2019 |
| Authors have demonstrated a previously undescribed role of CLDN7 as a ccRCC suppressor and suggest that loss of CLDN7 potentiates EMT and tumor progression. | Downregulation of CLDN7 due to promoter hypermethylation is associated with human clear cell renal cell carcinoma progression and poor prognosis.
Li Y, Gong Y, Ning X, Peng D, Liu L, He S, Gong K, Zhang C, Li X, Zhou L., Free PMC Article | 02/2/2019 |
| this paper shows that TGF-beta1 alters esophageal epithelial barrier function by attenuation of claudin-7 in eosinophilic esophagitis | TGF-β1 alters esophageal epithelial barrier function by attenuation of claudin-7 in eosinophilic esophagitis.
Nguyen N, Fernando SD, Biette KA, Hammer JA, Capocelli KE, Kitzenberg DA, Glover LE, Colgan SP, Furuta GT, Masterson JC., Free PMC Article | 12/22/2018 |
| In addition to replicating a previously identified genome-wide significant locus for corneal astigmatism near the PDGFRA gene, gene-based analysis identified three novel candidate genes, CLDN7, ACP2, and TNFAIP8L3, that warrant further investigation to understand their role in the pathogenesis of corneal astigmatism. (Meta-analysis) | A genome-wide association study of corneal astigmatism: The CREAM Consortium.
Shah RL, Li Q, Zhao W, Tedja MS, Tideman JWL, Khawaja AP, Fan Q, Yazar S, Williams KM, Verhoeven VJM, Xie J, Wang YX, Hess M, Nickels S, Lackner KJ, Pärssinen O, Wedenoja J, Biino G, Concas MP, Uitterlinden A, Rivadeneira F, Jaddoe VWV, Hysi PG, Sim X, Tan N, Tham YC, Sensaki S, Hofman A, Vingerling JR, Jonas JB, Mitchell P, Hammond CJ, Höhn R, Baird PN, Wong TY, Cheng CY, Teo YY, Mackey DA, Williams C, Saw SM, Klaver CCW, Guggenheim JA, Bailey-Wilson JE, CREAM Consortium., Free PMC Article | 11/17/2018 |
| the present study revealed the distinct expression profiles of claudin5, 7 and 8 in nonneoplastic mucosal tissues and gastric carcinoma tissues. Furthermore, the expression of these claudin proteins was highly associated with metastatic progression and prognosis in patients with gastric carcinoma | Differences in the expression profiles of claudin proteins in human gastric carcinoma compared with non‑neoplastic mucosa.
Yang L, Sun X, Meng X., Free PMC Article | 10/20/2018 |
| Immunohistochemical expression levels of cytoplasmic claudins 3 and 7 appear to be novel prognostic factors in triple-negative breast cancer. | High-level cytoplasmic claudin 3 expression is an independent predictor of poor survival in triple-negative breast cancer.
Jääskeläinen A, Soini Y, Jukkola-Vuorinen A, Auvinen P, Haapasaari KM, Karihtala P., Free PMC Article | 10/6/2018 |
| DICFM approach may be applied as an appropriate approach to quantify the immunohistochemical staining of claudin-7 on the cell membrane and claudin-7 may serve as a marker for identification of lung cancer | Immunohistochemical quantification of expression of a tight junction protein, claudin-7, in human lung cancer samples using digital image analysis method.
Lu Z, Liu Y, Xu J, Yin H, Yuan H, Gu J, Chen YH, Shi L, Chen D, Xie B. | 09/29/2018 |