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    Dnmt3b DNA methyltransferase 3B [ Mus musculus (house mouse) ]

    Gene ID: 13436, updated on 18-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    DNA methylation of miR-181a-5p mediated by DNMT3b drives renal interstitial fibrosis developed from acute kidney injury.

    DNA methylation of miR-181a-5p mediated by DNMT3b drives renal interstitial fibrosis developed from acute kidney injury.
    Liu H, Deng Y, Luo G, Yang Y, Xie B, Diao H, Chen M, Chen L, Xie P, Kwan HY, Zhao X, Sun X., Free PMC Article

    09/12/2024
    Suppression of DNMT2/3 by proinflammatory cytokines inhibits CtBP1/2-dependent genes to promote the occurrence of atrophic nonunion.

    Suppression of DNMT2/3 by proinflammatory cytokines inhibits CtBP1/2-dependent genes to promote the occurrence of atrophic nonunion.
    Chen X, Wang C, Zhao G, Li Z, Zhang W, Song T, Zhang C, Duan N.

    04/5/2024
    FOXC1 Promotes Osteoblastic Differentiation of Bone Marrow Mesenchymal Stem Cells via the Dnmt3b/CXCL12 Axis.

    FOXC1 Promotes Osteoblastic Differentiation of Bone Marrow Mesenchymal Stem Cells via the Dnmt3b/CXCL12 Axis.
    Zhang P, Feng B, Dai G, Niu K, Zhang L.

    03/1/2024
    Dnmt3b ablation affects fracture repair process by regulating apoptosis.

    Dnmt3b ablation affects fracture repair process by regulating apoptosis.
    Wang X, Ge Q, Zeng Q, Zou K, Bao Z, Ying J, Wu Z, Jin H, Chen J, Xu T., Free PMC Article

    02/29/2024
    DNMT3B Alleviates Liver Steatosis Induced by Chronic Low-grade LPS via Inhibiting CIDEA Expression.

    DNMT3B Alleviates Liver Steatosis Induced by Chronic Low-grade LPS via Inhibiting CIDEA Expression.
    Li Q, Wang W, Duan F, Wang Y, Chen S, Shi K, Xia Y, Li X, Gao Y, Liu G., Free PMC Article

    12/27/2023
    Dnmt3bas coordinates transcriptional induction and alternative exon inclusion to promote catalytically active Dnmt3b expression.

    Dnmt3bas coordinates transcriptional induction and alternative exon inclusion to promote catalytically active Dnmt3b expression.
    Dar MS, Mensah IK, He M, McGovern S, Sohal IS, Whitlock HC, Bippus NE, Ceminsky M, Emerson ML, Tan HJ, Hall MC, Gowher H., Free PMC Article

    10/12/2023
    Uterine deficiency of Dnmt3b impairs decidualization and causes consequent embryo implantation defects.

    Uterine deficiency of Dnmt3b impairs decidualization and causes consequent embryo implantation defects.
    Long J, Li W, Chen M, Ding Y, Chen X, Tong C, Li N, Liu X, He J, Peng C, Geng Y, Liu T, Mu X, Li F, Wang Y, Gao R.

    08/9/2023
    DNMT3B activates FGFR3-mediated endoplasmic reticulum stress by regulating PTPN2 promoter methylation to promote the development of atherosclerosis.

    DNMT3B activates FGFR3-mediated endoplasmic reticulum stress by regulating PTPN2 promoter methylation to promote the development of atherosclerosis.
    Zhang Z, Guo Q, Zhao Z, Nie M, Shi Q, Li E, Liu K, Yu H, Rao L, Li M.

    07/24/2023
    Pivotal role for S-nitrosylation of DNA methyltransferase 3B in epigenetic regulation of tumorigenesis.

    Pivotal role for S-nitrosylation of DNA methyltransferase 3B in epigenetic regulation of tumorigenesis.
    Okuda K, Nakahara K, Ito A, Iijima Y, Nomura R, Kumar A, Fujikawa K, Adachi K, Shimada Y, Fujio S, Yamamoto R, Takasugi N, Onuma K, Osaki M, Okada F, Ukegawa T, Takeuchi Y, Yasui N, Yamashita A, Marusawa H, Matsushita Y, Katagiri T, Shibata T, Uchida K, Niu SY, Lang NB, Nakamura T, Zhang KYJ, Lipton SA, Uehara T., Free PMC Article

    02/11/2023
    5-Methylcytosine and 5-Hydroxymethylcytosine in Scrapie-Infected Sheep and Mouse Brain Tissues.

    5-Methylcytosine and 5-Hydroxymethylcytosine in Scrapie-Infected Sheep and Mouse Brain Tissues.
    Hernaiz A, Sentre S, Betancor M, López-Pérez Ó, Salinas-Pena M, Zaragoza P, Badiola JJ, Toivonen JM, Bolea R, Martín-Burriel I., Free PMC Article

    02/4/2023
    Mechanisms and function of de novo DNA methylation in placental development reveals an essential role for DNMT3B.

    Mechanisms and function of de novo DNA methylation in placental development reveals an essential role for DNMT3B.
    Andrews S, Krueger C, Mellado-Lopez M, Hemberger M, Dean W, Perez-Garcia V, Hanna CW., Free PMC Article

    01/28/2023
    DNMT3B supports meso-endoderm differentiation from mouse embryonic stem cells.

    DNMT3B supports meso-endoderm differentiation from mouse embryonic stem cells.
    Lauria A, Meng G, Proserpio V, Rapelli S, Maldotti M, Polignano IL, Anselmi F, Incarnato D, Krepelova A, Donna D, Levra Levron C, Donati G, Molineris I, Neri F, Oliviero S., Free PMC Article

    01/28/2023
    DNA Methyltransferase 3b Accelerates the Process of Atherosclerosis.

    DNA Methyltransferase 3b Accelerates the Process of Atherosclerosis.
    Zhu L, Jia L, Liu N, Wu R, Guan G, Hui R, Xing Y, Zhang Y, Wang J., Free PMC Article

    04/23/2022
    DNA Methyltransferase 3b in Myeloid Cells Does Not Affect the Acute Immune Response in the Airways during Pseudomonas Pneumonia.

    DNA Methyltransferase 3b in Myeloid Cells Does Not Affect the Acute Immune Response in the Airways during Pseudomonas Pneumonia.
    Qin W, Brands X, Van't Veer C, de Vos AF, Scicluna BP, van der Poll T., Free PMC Article

    04/16/2022
    TCF3 is epigenetically silenced by EZH2 and DNMT3B and functions as a tumor suppressor in endometrial cancer.

    TCF3 is epigenetically silenced by EZH2 and DNMT3B and functions as a tumor suppressor in endometrial cancer.
    Gui T, Liu M, Yao B, Jiang H, Yang D, Li Q, Zeng X, Wang Y, Cao J, Deng Y, Li X, Xu P, Zhou L, Li D, Wang Z, Zen K, Huang DCS, Chen B, Wan G, Zhao Q., Free PMC Article

    03/26/2022
    Oxidative Stress-Induced Hypermethylation of KLF5 Promoter Mediated by DNMT3B Impairs Osteogenesis by Diminishing the Interaction with beta-Catenin.

    Oxidative Stress-Induced Hypermethylation of KLF5 Promoter Mediated by DNMT3B Impairs Osteogenesis by Diminishing the Interaction with β-Catenin.
    Li L, Wang H, Chen X, Li X, Wang G, Jie Z, Zhao X, Sun X, Huang H, Fan S, Xie Z, Wang J.

    03/5/2022
    Gene expression levels of DNA methyltransferase enzymes in Shank3-deficient mouse model of autism during early development.

    Gene expression levels of DNA methyltransferase enzymes in Shank3-deficient mouse model of autism during early development.
    Srancikova A, Reichova A, Bacova Z, Bakos J.

    01/22/2022
    PAX7 Balances the Cell Cycle Progression via Regulating Expression of Dnmt3b and Apobec2 in Differentiating PSCs.

    PAX7 Balances the Cell Cycle Progression via Regulating Expression of Dnmt3b and Apobec2 in Differentiating PSCs.
    Florkowska A, Meszka I, Nowacka J, Granica M, Jablonska Z, Zawada M, Truszkowski L, Ciemerych MA, Grabowska I., Free PMC Article

    11/22/2021
    Dnmt3b Deficiency in Myf5(+)-Brown Fat Precursor Cells Promotes Obesity in Female Mice.

    Dnmt3b Deficiency in Myf5(+)-Brown Fat Precursor Cells Promotes Obesity in Female Mice.
    Wang S, Cao Q, Cui X, Jing J, Li F, Shi H, Xue B, Shi H., Free PMC Article

    10/30/2021
    Dnmt3b catalytic activity is critical for its tumour suppressor function in lymphomagenesis and is associated with c-Met oncogenic signalling.

    Dnmt3b catalytic activity is critical for its tumour suppressor function in lymphomagenesis and is associated with c-Met oncogenic signalling.
    Lopusna K, Nowialis P, Opavska J, Abraham A, Riva A, Opavsky R., Free PMC Article

    10/9/2021
    Decreases in different Dnmt3b activities drive distinct development of hematologic malignancies in mice.

    Decreases in different Dnmt3b activities drive distinct development of hematologic malignancies in mice.
    Lopusna K, Nowialis P, Opavska J, Abraham A, Riva A, Haney SL, Opavsky R., Free PMC Article

    09/4/2021
    Bronchial epithelial DNA methyltransferase 3b dampens pulmonary immune responses during Pseudomonas aeruginosa infection.

    Bronchial epithelial DNA methyltransferase 3b dampens pulmonary immune responses during Pseudomonas aeruginosa infection.
    Qin W, Brands X, Van't Veer C, F de Vos A, Sirard JC, J T H Roelofs J, P Scicluna B, van der Poll T., Free PMC Article

    08/28/2021
    Dnmt3b regulates DUX4 expression in a tissue-dependent manner in transgenic D4Z4 mice.

    Dnmt3b regulates DUX4 expression in a tissue-dependent manner in transgenic D4Z4 mice.
    Bouwman LF, den Hamer B, Verveer EP, Lerink LJS, Krom YD, van der Maarel SM, de Greef JC., Free PMC Article

    07/31/2021
    Dnmt3b ablation impairs fracture repair through upregulation of Notch pathway.

    Dnmt3b ablation impairs fracture repair through upregulation of Notch pathway.
    Ying J, Xu T, Wang C, Jin H, Tong P, Guan J, Abu-Amer Y, O'Keefe R, Shen J., Free PMC Article

    06/26/2021
    The inactive Dnmt3b3 isoform preferentially enhances Dnmt3b-mediated DNA methylation.

    The inactive Dnmt3b3 isoform preferentially enhances Dnmt3b-mediated DNA methylation.
    Zeng Y, Ren R, Kaur G, Hardikar S, Ying Z, Babcock L, Gupta E, Zhang X, Chen T, Cheng X., Free PMC Article

    06/12/2021
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