DNA methylation of miR-181a-5p mediated by DNMT3b drives renal interstitial fibrosis developed from acute kidney injury. | DNA methylation of miR-181a-5p mediated by DNMT3b drives renal interstitial fibrosis developed from acute kidney injury. Liu H, Deng Y, Luo G, Yang Y, Xie B, Diao H, Chen M, Chen L, Xie P, Kwan HY, Zhao X, Sun X., Free PMC Article | 09/12/2024 |
Suppression of DNMT2/3 by proinflammatory cytokines inhibits CtBP1/2-dependent genes to promote the occurrence of atrophic nonunion. | Suppression of DNMT2/3 by proinflammatory cytokines inhibits CtBP1/2-dependent genes to promote the occurrence of atrophic nonunion. Chen X, Wang C, Zhao G, Li Z, Zhang W, Song T, Zhang C, Duan N. | 04/5/2024 |
FOXC1 Promotes Osteoblastic Differentiation of Bone Marrow Mesenchymal Stem Cells via the Dnmt3b/CXCL12 Axis. | FOXC1 Promotes Osteoblastic Differentiation of Bone Marrow Mesenchymal Stem Cells via the Dnmt3b/CXCL12 Axis. Zhang P, Feng B, Dai G, Niu K, Zhang L. | 03/1/2024 |
Dnmt3b ablation affects fracture repair process by regulating apoptosis. | Dnmt3b ablation affects fracture repair process by regulating apoptosis. Wang X, Ge Q, Zeng Q, Zou K, Bao Z, Ying J, Wu Z, Jin H, Chen J, Xu T., Free PMC Article | 02/29/2024 |
DNMT3B Alleviates Liver Steatosis Induced by Chronic Low-grade LPS via Inhibiting CIDEA Expression. | DNMT3B Alleviates Liver Steatosis Induced by Chronic Low-grade LPS via Inhibiting CIDEA Expression. Li Q, Wang W, Duan F, Wang Y, Chen S, Shi K, Xia Y, Li X, Gao Y, Liu G., Free PMC Article | 12/27/2023 |
Dnmt3bas coordinates transcriptional induction and alternative exon inclusion to promote catalytically active Dnmt3b expression. | Dnmt3bas coordinates transcriptional induction and alternative exon inclusion to promote catalytically active Dnmt3b expression. Dar MS, Mensah IK, He M, McGovern S, Sohal IS, Whitlock HC, Bippus NE, Ceminsky M, Emerson ML, Tan HJ, Hall MC, Gowher H., Free PMC Article | 10/12/2023 |
Uterine deficiency of Dnmt3b impairs decidualization and causes consequent embryo implantation defects. | Uterine deficiency of Dnmt3b impairs decidualization and causes consequent embryo implantation defects. Long J, Li W, Chen M, Ding Y, Chen X, Tong C, Li N, Liu X, He J, Peng C, Geng Y, Liu T, Mu X, Li F, Wang Y, Gao R. | 08/9/2023 |
DNMT3B activates FGFR3-mediated endoplasmic reticulum stress by regulating PTPN2 promoter methylation to promote the development of atherosclerosis. | DNMT3B activates FGFR3-mediated endoplasmic reticulum stress by regulating PTPN2 promoter methylation to promote the development of atherosclerosis. Zhang Z, Guo Q, Zhao Z, Nie M, Shi Q, Li E, Liu K, Yu H, Rao L, Li M. | 07/24/2023 |
Pivotal role for S-nitrosylation of DNA methyltransferase 3B in epigenetic regulation of tumorigenesis. | Pivotal role for S-nitrosylation of DNA methyltransferase 3B in epigenetic regulation of tumorigenesis. Okuda K, Nakahara K, Ito A, Iijima Y, Nomura R, Kumar A, Fujikawa K, Adachi K, Shimada Y, Fujio S, Yamamoto R, Takasugi N, Onuma K, Osaki M, Okada F, Ukegawa T, Takeuchi Y, Yasui N, Yamashita A, Marusawa H, Matsushita Y, Katagiri T, Shibata T, Uchida K, Niu SY, Lang NB, Nakamura T, Zhang KYJ, Lipton SA, Uehara T., Free PMC Article | 02/11/2023 |
5-Methylcytosine and 5-Hydroxymethylcytosine in Scrapie-Infected Sheep and Mouse Brain Tissues. | 5-Methylcytosine and 5-Hydroxymethylcytosine in Scrapie-Infected Sheep and Mouse Brain Tissues. Hernaiz A, Sentre S, Betancor M, López-Pérez Ó, Salinas-Pena M, Zaragoza P, Badiola JJ, Toivonen JM, Bolea R, Martín-Burriel I., Free PMC Article | 02/4/2023 |
Mechanisms and function of de novo DNA methylation in placental development reveals an essential role for DNMT3B. | Mechanisms and function of de novo DNA methylation in placental development reveals an essential role for DNMT3B. Andrews S, Krueger C, Mellado-Lopez M, Hemberger M, Dean W, Perez-Garcia V, Hanna CW., Free PMC Article | 01/28/2023 |
DNMT3B supports meso-endoderm differentiation from mouse embryonic stem cells. | DNMT3B supports meso-endoderm differentiation from mouse embryonic stem cells. Lauria A, Meng G, Proserpio V, Rapelli S, Maldotti M, Polignano IL, Anselmi F, Incarnato D, Krepelova A, Donna D, Levra Levron C, Donati G, Molineris I, Neri F, Oliviero S., Free PMC Article | 01/28/2023 |
DNA Methyltransferase 3b Accelerates the Process of Atherosclerosis. | DNA Methyltransferase 3b Accelerates the Process of Atherosclerosis. Zhu L, Jia L, Liu N, Wu R, Guan G, Hui R, Xing Y, Zhang Y, Wang J., Free PMC Article | 04/23/2022 |
DNA Methyltransferase 3b in Myeloid Cells Does Not Affect the Acute Immune Response in the Airways during Pseudomonas Pneumonia. | DNA Methyltransferase 3b in Myeloid Cells Does Not Affect the Acute Immune Response in the Airways during Pseudomonas Pneumonia. Qin W, Brands X, Van't Veer C, de Vos AF, Scicluna BP, van der Poll T., Free PMC Article | 04/16/2022 |
TCF3 is epigenetically silenced by EZH2 and DNMT3B and functions as a tumor suppressor in endometrial cancer. | TCF3 is epigenetically silenced by EZH2 and DNMT3B and functions as a tumor suppressor in endometrial cancer. Gui T, Liu M, Yao B, Jiang H, Yang D, Li Q, Zeng X, Wang Y, Cao J, Deng Y, Li X, Xu P, Zhou L, Li D, Wang Z, Zen K, Huang DCS, Chen B, Wan G, Zhao Q., Free PMC Article | 03/26/2022 |
Oxidative Stress-Induced Hypermethylation of KLF5 Promoter Mediated by DNMT3B Impairs Osteogenesis by Diminishing the Interaction with beta-Catenin. | Oxidative Stress-Induced Hypermethylation of KLF5 Promoter Mediated by DNMT3B Impairs Osteogenesis by Diminishing the Interaction with β-Catenin. Li L, Wang H, Chen X, Li X, Wang G, Jie Z, Zhao X, Sun X, Huang H, Fan S, Xie Z, Wang J. | 03/5/2022 |
Gene expression levels of DNA methyltransferase enzymes in Shank3-deficient mouse model of autism during early development. | Gene expression levels of DNA methyltransferase enzymes in Shank3-deficient mouse model of autism during early development. Srancikova A, Reichova A, Bacova Z, Bakos J. | 01/22/2022 |
PAX7 Balances the Cell Cycle Progression via Regulating Expression of Dnmt3b and Apobec2 in Differentiating PSCs. | PAX7 Balances the Cell Cycle Progression via Regulating Expression of Dnmt3b and Apobec2 in Differentiating PSCs. Florkowska A, Meszka I, Nowacka J, Granica M, Jablonska Z, Zawada M, Truszkowski L, Ciemerych MA, Grabowska I., Free PMC Article | 11/22/2021 |
Dnmt3b Deficiency in Myf5(+)-Brown Fat Precursor Cells Promotes Obesity in Female Mice. | Dnmt3b Deficiency in Myf5(+)-Brown Fat Precursor Cells Promotes Obesity in Female Mice. Wang S, Cao Q, Cui X, Jing J, Li F, Shi H, Xue B, Shi H., Free PMC Article | 10/30/2021 |
Dnmt3b catalytic activity is critical for its tumour suppressor function in lymphomagenesis and is associated with c-Met oncogenic signalling. | Dnmt3b catalytic activity is critical for its tumour suppressor function in lymphomagenesis and is associated with c-Met oncogenic signalling. Lopusna K, Nowialis P, Opavska J, Abraham A, Riva A, Opavsky R., Free PMC Article | 10/9/2021 |
Decreases in different Dnmt3b activities drive distinct development of hematologic malignancies in mice. | Decreases in different Dnmt3b activities drive distinct development of hematologic malignancies in mice. Lopusna K, Nowialis P, Opavska J, Abraham A, Riva A, Haney SL, Opavsky R., Free PMC Article | 09/4/2021 |
Bronchial epithelial DNA methyltransferase 3b dampens pulmonary immune responses during Pseudomonas aeruginosa infection. | Bronchial epithelial DNA methyltransferase 3b dampens pulmonary immune responses during Pseudomonas aeruginosa infection. Qin W, Brands X, Van't Veer C, F de Vos A, Sirard JC, J T H Roelofs J, P Scicluna B, van der Poll T., Free PMC Article | 08/28/2021 |
Dnmt3b regulates DUX4 expression in a tissue-dependent manner in transgenic D4Z4 mice. | Dnmt3b regulates DUX4 expression in a tissue-dependent manner in transgenic D4Z4 mice. Bouwman LF, den Hamer B, Verveer EP, Lerink LJS, Krom YD, van der Maarel SM, de Greef JC., Free PMC Article | 07/31/2021 |
Dnmt3b ablation impairs fracture repair through upregulation of Notch pathway. | Dnmt3b ablation impairs fracture repair through upregulation of Notch pathway. Ying J, Xu T, Wang C, Jin H, Tong P, Guan J, Abu-Amer Y, O'Keefe R, Shen J., Free PMC Article | 06/26/2021 |
The inactive Dnmt3b3 isoform preferentially enhances Dnmt3b-mediated DNA methylation. | The inactive Dnmt3b3 isoform preferentially enhances Dnmt3b-mediated DNA methylation. Zeng Y, Ren R, Kaur G, Hardikar S, Ying Z, Babcock L, Gupta E, Zhang X, Chen T, Cheng X., Free PMC Article | 06/12/2021 |