| FIGNL1 AAA+ ATPase remodels RAD51 and DMC1 filaments in pre-meiotic DNA replication and meiotic recombination. | FIGNL1 AAA+ ATPase remodels RAD51 and DMC1 filaments in pre-meiotic DNA replication and meiotic recombination.
Ito M, Furukohri A, Matsuzaki K, Fujita Y, Toyoda A, Shinohara A., Free PMC Article | 11/1/2023 |
| The FLIP-FIGNL1 complex regulates the dissociation of RAD51/DMC1 in homologous recombination and replication fork restart. | The FLIP-FIGNL1 complex regulates the dissociation of RAD51/DMC1 in homologous recombination and replication fork restart.
Zhang Q, Fan J, Xu W, Cao H, Qiu C, Xiong Y, Zhao H, Wang Y, Huang J, Yu C., Free PMC Article | 09/11/2023 |
| The Configuration of RPA, RAD51, and DMC1 Binding in Meiosis Reveals the Nature of Critical Recombination Intermediates. | The Configuration of RPA, RAD51, and DMC1 Binding in Meiosis Reveals the Nature of Critical Recombination Intermediates.
Hinch AG, Becker PW, Li T, Moralli D, Zhang G, Bycroft C, Green C, Keeney S, Shi Q, Davies B, Donnelly P., Free PMC Article | 09/26/2020 |
| Super-resolution imaging of RAD51 and DMC1 in DNA repair foci reveals dynamic distribution patterns in meiotic prophase. | Super-resolution imaging of RAD51 and DMC1 in DNA repair foci reveals dynamic distribution patterns in meiotic prophase.
Slotman JA, Paul MW, Carofiglio F, de Gruiter HM, Vergroesen T, Koornneef L, van Cappellen WA, Houtsmuller AB, Baarends WM., Free PMC Article | 08/22/2020 |
| In this study, we created a mouse model of a putative infertility allele, DMC1M200V. DMC1 encodes a RecA homolog essential for meiotic recombination and fertility in mice..we found that Dmc1M200V/M200V male and female mice are fully fertile and do not exhibit any gonadal abnormalities | A putative human infertility allele of the meiotic recombinase DMC1 does not affect fertility in mice.
Tran TN, Schimenti JC., Free PMC Article | 05/11/2019 |
| we observed the occurrence of synaptonemal complex bridges between bivalents, most likely representing chromosome translocation events that may involve DMC1, RAD51 or 53BP1. | Transition from a meiotic to a somatic-like DNA damage response during the pachytene stage in mouse meiosis.
Enguita-Marruedo A, Martín-Ruiz M, García E, Gil-Fernández A, Parra MT, Viera A, Rufas JS, Page J., Free PMC Article | 03/16/2019 |
| The DMC1 was highly variable from cell to cell, whereas foci of the crossover marker MLH1 showed little variability. | Homeostatic control of recombination is implemented progressively in mouse meiosis.
Cole F, Kauppi L, Lange J, Roig I, Wang R, Keeney S, Jasin M., Free PMC Article | 06/9/2012 |
| RAD51AP1 foci colocalize with a subset of DMC1 foci in spermatocytes. | Molecular basis for enhancement of the meiotic DMC1 recombinase by RAD51 associated protein 1 (RAD51AP1).
Dray E, Dunlop MH, Kauppi L, San Filippo J, Wiese C, Tsai MS, Begovic S, Schild D, Jasin M, Keeney S, Sung P., Free PMC Article | 05/14/2011 |
| Dmc1(Mei11) exposes a sex difference in recombination in that a significant portion of female oocytes can compensate for DMC1 deficiency to undergo crossing-over and complete gametogenesis. | A dominant, recombination-defective allele of Dmc1 causing male-specific sterility.
Bannister LA, Pezza RJ, Donaldson JR, de Rooij DG, Schimenti KJ, Camerini-Otero RD, Schimenti JC., Free PMC Article | 01/21/2010 |
| Mei1 can be positioned upstream of Dmc1 in the genetic pathway that operates during mammalian meiosis | Mei1 is epistatic to Dmc1 during mouse meiosis.
Reinholdt LG, Schimenti JC. | 01/21/2010 |
| p53 might be involved in homologous recombination and/or checkpoint function by directly binding to DMC1 protein to repress genomic instability in meiotic germ cells | p53 Protein interacts specifically with the meiosis-specific mammalian RecA-like protein DMC1 in meiosis.
Habu T, Wakabayashi N, Yoshida K, Yomogida K, Nishimune Y, Morita T. | 01/21/2010 |
| TBPIP/HOP2 directly binds to DNA and functions as an activator for DMC1 during the homologous pairing step in meiosis | Positive role of the mammalian TBPIP/HOP2 protein in DMC1-mediated homologous pairing.
Enomoto R, Kinebuchi T, Sato M, Yagi H, Shibata T, Kurumizaka H, Yokoyama S. | 01/21/2010 |
| data reveal an interplay among Hop2, Mnd1 and Rad51 and Dmc1 in the formation of the first recombination intermediates during meiosis | The Hop2 and Mnd1 proteins act in concert with Rad51 and Dmc1 in meiotic recombination.
Petukhova GV, Pezza RJ, Vanevski F, Ploquin M, Masson JY, Camerini-Otero RD. | 01/21/2010 |