| CPEB2 inhibit cell proliferation through upregulating p21 mRNA stability in glioma. | CPEB2 inhibit cell proliferation through upregulating p21 mRNA stability in glioma.
Zhao G, Zhao Z, Xia M, Xiao L, Zhu B, Wang H, Li X, Di J., Free PMC Article | 02/12/2024 |
| CPEB2 enhances cell growth and angiogenesis by upregulating ARPC5 mRNA stability in multiple myeloma. | CPEB2 enhances cell growth and angiogenesis by upregulating ARPC5 mRNA stability in multiple myeloma.
Zeng P, Wang F, Long X, Cao Y, Wen F, Li J, Luo Z., Free PMC Article | 05/30/2023 |
| CPEB2 m6A methylation regulates blood-tumor barrier permeability by regulating splicing factor SRSF5 stability. | CPEB2 m6A methylation regulates blood-tumor barrier permeability by regulating splicing factor SRSF5 stability.
Zhang M, Yang C, Ruan X, Liu X, Wang D, Liu L, Shao L, Wang P, Dong W, Xue Y., Free PMC Article | 09/24/2022 |
| The RNA binding protein CPEB2 regulates hormone sensing in mammary gland development and luminal breast cancer. | The RNA binding protein CPEB2 regulates hormone sensing in mammary gland development and luminal breast cancer.
Pascual R, Martín J, Salvador F, Reina O, Chanes V, Millanes-Romero A, Suñer C, Fernández-Miranda G, Bartomeu A, Huang YS, Gomis RR, Méndez R., Free PMC Article | 04/16/2022 |
| A positive feedback self-regulatory loop between miR-210 and HIF-1alpha mediated by CPEB2 is involved in trophoblast syncytialization: implication of trophoblast malfunction in preeclampsiadagger. | A positive feedback self-regulatory loop between miR-210 and HIF-1α mediated by CPEB2 is involved in trophoblast syncytialization: implication of trophoblast malfunction in preeclampsia†.
Wang H, Zhao Y, Luo R, Bian X, Wang Y, Shao X, Li YX, Liu M, Wang YL. | 08/21/2021 |
| Data demonstrated an increased occurrence of both SRSF3 and the CPEB2B isoform in triple negative breast cancer (TNBC), and identified a consensus binding motif for SRSF3 in the exon promoting the CPEB2B isoform. The study also suggests that the splicing event, which promotes the expression of CPEB2B, is driven by SRSF3 as well as linked to aggressive growth in metastatic TNBC. | Serine/Arginine-Rich Splicing Factor 3 Modulates the Alternative Splicing of Cytoplasmic Polyadenylation Element Binding Protein 2.
DeLigio JT, Stevens SC, Nazario-Muñoz GS, MacKnight HP, Doe KK, Chalfant CE, Park MA., Free PMC Article | 06/20/2020 |
| CPEB2, presumably the isoform A, plays a key role in suppressing tumorigenesis in mammary epithelial cells by repressing EMT, migration, invasion, proliferation and stem-like cells phenotype, via multiple targets, including a newly-identified translational target p53. | Tumor suppressor role of cytoplasmic polyadenylation element binding protein 2 (CPEB2) in human mammary epithelial cells.
Tordjman J, Majumder M, Amiri M, Hasan A, Hess D, Lala PK., Free PMC Article | 12/14/2019 |
| Our findings demonstrated the overexpression of miR-885-5p in liver metastasis and its roles in inducing CRC metastasis, potentiating development of miR-885-5p inhibitor to treat advanced CRC in the future. | Identification of microRNA 885-5p as a novel regulator of tumor metastasis by targeting CPEB2 in colorectal cancer.
Lam CS, Ng L, Chow AK, Wan TM, Yau S, Cheng NS, Wong SK, Man JH, Lo OS, Foo DC, Poon JT, Pang RW, Law WL., Free PMC Article | 03/10/2018 |
| Long non-coding RNA TUG1 mediates methotrexate resistance in colorectal cancer via miR-186/CPEB2 axis. | TUG1 mediates methotrexate resistance in colorectal cancer via miR-186/CPEB2 axis.
Li C, Gao Y, Li Y, Ding D. | 09/2/2017 |
| CPEB1, 2, and 4, are essential to successful mitotic cell division. | Global Analysis of CPEBs Reveals Sequential and Non-Redundant Functions in Mitotic Cell Cycle.
Giangarrà V, Igea A, Castellazzi CL, Bava FA, Mendez R., Free PMC Article | 06/4/2016 |
| findings demonstrate that the regulation of CPEB2 mRNA splicing is a key mechanism in AnR and a driving force in TNBC metastasis | The Alternative Splicing of Cytoplasmic Polyadenylation Element Binding Protein 2 Drives Anoikis Resistance and the Metastasis of Triple Negative Breast Cancer.
Johnson RM, Vu NT, Griffin BP, Gentry AE, Archer KJ, Chalfant CE, Park MA., Free PMC Article | 02/20/2016 |
| Functional studies of the mouse homolog | CPEB2, a novel putative translational regulator in mouse haploid germ cells.
Kurihara Y, Tokuriki M, Myojin R, Hori T, Kuroiwa A, Matsuda Y, Sakurai T, Kimura M, Hecht NB, Uesugi S. | 07/16/2003 |