| Hepatocyte Adenosine Kinase Promotes Excessive Fat Deposition and Liver Inflammation. | Hepatocyte Adenosine Kinase Promotes Excessive Fat Deposition and Liver Inflammation.
Li H, Zheng J, Xu Q, Yang Y, Zhou J, Guo X, Cai Y, Cai JJ, Xie L, Awika J, Han X, Li Q, Kennedy L, Francis H, Glaser S, Huo Y, Alpini G, Wu C., Free PMC Article | 12/31/2022 |
| Genetic variations of adenosine kinase as predictable biomarkers of efficacy of vagus nerve stimulation in patients with pharmacoresistant epilepsy. | Genetic variations of adenosine kinase as predictable biomarkers of efficacy of vagus nerve stimulation in patients with pharmacoresistant epilepsy.
Zhang Y, Wang X, Tang C, Guan Y, Chen F, Gao Q, Wang J, Zhou J, Zhai F, Boison D, Luan G, Li T., Free PMC Article | 04/16/2022 |
| Adenosine kinase deficiency: Three new cases and diagnostic value of hypermethioninemia. | Adenosine kinase deficiency: Three new cases and diagnostic value of hypermethioninemia.
Becker PH, Demir Z, Mozer Glassberg Y, Sevin C, Habes D, Imbard A, Mussini C, Rozenfeld Bar Lev M, Davit-Spraul A, Benoist JF, Thérond P, Slama A, Jacquemin E, Gonzales E, Gaignard P. | 08/7/2021 |
| The results of this study showed that over-expression of the major adenosine removing enzyme ADK in reactive astrocytes and subpopulation of remaining neurons in Rasmussen Encephalitis patients plays an important role in the epileptogensis of Rasmussen Encephalitis. | Upregulation of Neuronal Adenosine A1 Receptor in Human Rasmussen Encephalitis.
Luan G, Wang X, Gao Q, Guan Y, Wang J, Deng J, Zhai F, Chen Y, Li T. | 08/26/2017 |
| ADA and ADK are involved in glioma progression; increased ADA and ADK levels in peritumoral tissues may be associated with epilepsy in glioma patients. | Adenosine deaminase and adenosine kinase expression in human glioma and their correlation with glioma‑associated epilepsy.
Huang J, He Y, Chen M, Du J, Li G, Li S, Liu W, Long X., Free PMC Article | 08/13/2016 |
| rs11001109 rare allele homozygosity is associated with increased risk of post-traumatic epilepsy development after brain injury. | Genetic variation in the adenosine regulatory cycle is associated with posttraumatic epilepsy development.
Diamond ML, Ritter AC, Jackson EK, Conley YP, Kochanek PM, Boison D, Wagner AK., Free PMC Article | 10/17/2015 |
| The results of this study suggest that upregulation of ADK is a common pathologic component of FCDIIB. | Adenosine kinase expression in cortical dysplasia with balloon cells: analysis of developmental lineage of cell types.
Luan G, Gao Q, Zhai F, Zhou J, Liu C, Chen Y, Li T. | 03/21/2015 |
| These results suggest that upregulation of ADK is a common pathologic hallmark of Rasmussen encephalitis and that ADK might be a target in the treatment of epilepsy associated with Rasmussen encephalitis. | Upregulation of adenosine kinase in Rasmussen encephalitis.
Luan G, Gao Q, Guan Y, Zhai F, Zhou J, Liu C, Chen Y, Yao K, Qi X, Li T., Free PMC Article | 12/21/2013 |
| Data show that we a significantly higher expression of ADK in the peritumoral infiltrated tissue of patients with epilepsy than in patients without epilepsy. | Overexpression of ADK in human astrocytic tumors and peritumoral tissue is related to tumor-associated epilepsy.
de Groot M, Iyer A, Zurolo E, Anink J, Heimans JJ, Boison D, Reijneveld JC, Aronica E., Free PMC Article | 02/25/2012 |
| The results of this study suggested that dysregulation of ADK in astrocytes is a common pathologic hallmark of temporal lobe epilepsy. | Upregulation of adenosine kinase in astrocytes in experimental and human temporal lobe epilepsy.
Aronica E, Zurolo E, Iyer A, de Groot M, Anink J, Carbonell C, van Vliet EA, Baayen JC, Boison D, Gorter JA., Free PMC Article | 11/5/2011 |
| The catalytic properties, gene expression and protein levels of certain proteins involved in mitochondrial ATP synthesis, such as F1F0-ATPase, ANT and AK, in human skin fibroblasts with trisomic karyotype, compared them with euploid fibroblasts. | Impairment of F1F0-ATPase, adenine nucleotide translocator and adenylate kinase causes mitochondrial energy deficit in human skin fibroblasts with chromosome 21 trisomy.
Valenti D, Tullo A, Caratozzolo MF, Merafina RS, Scartezzini P, Marra E, Vacca RA. | 10/23/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (3) articlesContribution of adenosine related genes to the risk of depression with disturbed sleep.
Gass N, Ollila HM, Utge S, Partonen T, Kronholm E, Pirkola S, Suhonen J, Silander K, Porkka-Heiskanen T, Paunio T. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
Grupe A, Li Y, Rowland C, Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell TJ, Cherny S, Doil L, Tacey K, van Luchene R, Myers A, Wavrant-De Vrièze F, Kaleem M, Hollingworth P, Jehu L, Foy C, Archer N, Hamilton G, Holmans P, Morris CM, Catanese J, Sninsky J, White TJ, Powell J, Hardy J, O'Donovan M, Lovestone S, Jones L, Morris JC, Thal L, Owen M, Williams J, Goate A. | 12/2/2009 |
| This study reports for the first time subcellular localization of the enzyme AdK in mammalian cells. | Subcellular localization of adenosine kinase in mammalian cells: The long isoform of AdK is localized in the nucleus.
Cui XA, Singh B, Park J, Gupta RS. | 01/21/2010 |
| both deoxycytidine kinase and adenosine kinase are involved in this model of ADA deficiency | Inhibition of deoxynucleoside kinases in human thymocytes prevents dATP accumulation and induction of apoptosis.
Joachims ML, Marble P, Knott-Craig C, Pastuszko P, Blackburn MR, Thompson LF., Free PMC Article | 01/21/2010 |
| adenosine kinase gene expression was significantly higher in cancer than in normal-appearing tissue, in line with our previous measurements of adenosine kinase enzyme activities in colorectal tumor samples | Adenosine kinase gene expression in human colorectal cancer.
Giglioni S, Leoncini R, Aceto E, Chessa A, Civitelli S, Bernini A, Tanzini G, Carraro F, Pucci A, Vannoni D. | 01/21/2010 |
| role for HIF-1alpha in transcriptional repression of AK in hypoxia | HIF-1-dependent repression of adenosine kinase attenuates hypoxia-induced vascular leak.
Morote-Garcia JC, Rosenberger P, Kuhlicke J, Eltzschig HK. | 01/21/2010 |
| Equilibrative nucleoside transporters (hENT1, hENT2) together with adenosine kinase and 5'-nucleotidase play a crucial role in the regulation of CFTR through an adenosine-dependent pathway in human airway epithelia. | Coupling of CFTR-mediated anion secretion to nucleoside transporters and adenosine homeostasis in Calu-3 cells.
Szkotak AJ, Ng AM, Man SF, Baldwin SA, Cass CE, Young JD, Duszyk M. | 01/21/2010 |