| CircNDST1 promotes papillary thyroid cancer progression via its interaction with CSNK2A1 to activate the PI3K-Akt pathway and epithelial-mesenchymal transition. | CircNDST1 promotes papillary thyroid cancer progression via its interaction with CSNK2A1 to activate the PI3K-Akt pathway and epithelial-mesenchymal transition.
Shu C, Wang S, Hu J, Xu M, Deng H, Maimaiti Y, Huang T., Free PMC Article | 02/24/2023 |
| A Ca(2+)-Dependent Switch Activates Axonal Casein Kinase 2alpha Translation and Drives G3BP1 Granule Disassembly for Axon Regeneration. | A Ca(2+)-Dependent Switch Activates Axonal Casein Kinase 2α Translation and Drives G3BP1 Granule Disassembly for Axon Regeneration.
Sahoo PK, Kar AN, Samra N, Terenzio M, Patel P, Lee SJ, Miller S, Thames E, Jones B, Kawaguchi R, Coppola G, Fainzilber M, Twiss JL., Free PMC Article | 09/4/2021 |
| Protein Kinase CK2 Regulates B Cell Development and Differentiation. | Protein Kinase CK2 Regulates B Cell Development and Differentiation.
Wei H, Yang W, Hong H, Yan Z, Qin H, Benveniste EN., Free PMC Article | 08/14/2021 |
| Myeloid Cell CK2 Regulates Inflammation and Resistance to Bacterial Infection. | Myeloid Cell CK2 Regulates Inflammation and Resistance to Bacterial Infection.
Larson SR, Bortell N, Illies A, Crisler WJ, Matsuda JL, Lenz LL., Free PMC Article | 07/31/2021 |
| Phosphorylation of Syntaxin-1a by casein kinase 2alpha regulates pre-synaptic vesicle exocytosis from the reserve pool. | Phosphorylation of Syntaxin-1a by casein kinase 2α regulates pre-synaptic vesicle exocytosis from the reserve pool.
Shi VH, Craig TJ, Bishop P, Nakamura Y, Rocca D, Wilkinson KA, Henley JM., Free PMC Article | 05/8/2021 |
| A N-terminally deleted form of the CK2alpha' catalytic subunit is sufficient to support cell viability. | A N-terminally deleted form of the CK2α' catalytic subunit is sufficient to support cell viability.
Borgo C, D'Amore C, Cesaro L, Itami K, Hirota T, Salvi M, Pinna LA. | 03/13/2021 |
| Down-regulation of CK2alpha correlates with decreased expression levels of DNA replication minichromosome maintenance protein complex (MCM) genes. | Down-regulation of CK2α correlates with decreased expression levels of DNA replication minichromosome maintenance protein complex (MCM) genes.
Schaefer S, Doktor TK, Frederiksen SB, Chea K, Hlavacova M, Bruun GH, Rabjerg M, Andresen BS, Dominguez I, Guerra B., Free PMC Article | 11/21/2020 |
| beta-catenin stimulates Tcf7l1 degradation through recruitment of casein kinase 2 in mouse embryonic stem cells. | β-catenin stimulates Tcf7l1 degradation through recruitment of casein kinase 2 in mouse embryonic stem cells.
Zhang Y, Zhu Z, Ding H, Wan S, Zhang X, Li Y, Ji J, Wang X, Zhang M, Ye SD. | 10/24/2020 |
| Effects of Casein Kinase 2 Alpha 1 Gene Expression on Mice Liver Susceptible to Type 2 Diabetes Mellitus and Obesity. | Effects of Casein Kinase 2 Alpha 1 Gene Expression on Mice Liver Susceptible to Type 2 Diabetes Mellitus and Obesity.
Lan YC, Wang YH, Chen HH, Lo SF, Chen SY, Tsai FJ., Free PMC Article | 10/10/2020 |
| Results find that CK2alpha subunit has no role in GN11 neuronal cell adhesion or migration. | Protein Kinase CK2 Subunits Differentially Perturb the Adhesion and Migration of GN11 Cells: A Model of Immature Migrating Neurons.
Lettieri A, Borgo C, Zanieri L, D'Amore C, Oleari R, Paganoni A, Pinna LA, Cariboni A, Salvi M., Free PMC Article | 04/25/2020 |
| High CK2 alpha expression is associated with glioblastoma. | Up-Regulation of the Alpha Prime Subunit of Protein Kinase CK2 as a Marker of Fast Proliferation in GL261 Cultured Cells.
Villamañan L, Alcaraz E, Pinna LA, Ruzzene M, Itarte E, Arús C, Plana M, Candiota AP. | 04/4/2020 |
| these data suggest that Fcgamma receptor/reactive oxygen species/CK2alpha is a key inducer of NF-kappaB activation in airway epithelial cells in a murine model of asthma | FcγR/ROS/CK2α Is the Key Inducer of NF-κB Activation in a Murine Model of Asthma.
Kim JM, Kim HK, Im YN, Bae YS, Im SY, Lee HK. | 04/7/2018 |
| Data (including data from studies using knockout mice) suggest that Brg1 is phosphorylated by casein kinase 2 (Ck2; Ck2alpha1 and Ck2alpha-prime are catalytic subunits) in proliferating skeletal myoblasts; Brg1 is catalytic subunit of SWI/SNF chromatin-remodeling enzymes; Ck2-mediated phosphorylation of Brg1 appears to regulate myoblast proliferation. (Brg1 = Brahma-related gene 1 protein) | Casein kinase 2-mediated phosphorylation of Brahma-related gene 1 controls myoblast proliferation and contributes to SWI/SNF complex composition.
Padilla-Benavides T, Nasipak BT, Paskavitz AL, Haokip DT, Schnabl JM, Nickerson JA, Imbalzano AN., Free PMC Article | 12/23/2017 |
| Casein kinase 2 plays a central role in striatal physiology and in severity of l-DOPA-induced dyskinesia. | CK2 Oppositely Modulates l-DOPA-Induced Dyskinesia via Striatal Projection Neurons Expressing D1 or D2 Receptors.
Cortés M, Malave L, Castello J, Flajolet M, Cenci MA, Friedman E, Rebholz H., Free PMC Article | 12/16/2017 |
| Casein kinase 1 (alpha, delta and epsilon) localize at the spindle poles, but may not be essential for mammalian oocyte meiotic progression. | Casein kinase 1 (α, δ and ε) localize at the spindle poles, but may not be essential for mammalian oocyte meiotic progression.
Qi ST, Wang ZB, Huang L, Liang LF, Xian YX, Ouyang YC, Hou Y, Sun QY, Wang WH., Free PMC Article | 03/5/2016 |
| These data support a model in which activated Akt enhances rRNA synthesis both by preventing TIF-IA degradation and phosphorylating CK2alpha, which in turn phosphorylates TIF-IA. | Akt activation enhances ribosomal RNA synthesis through casein kinase II and TIF-IA.
Nguyen le XT, Mitchell BS., Free PMC Article | 03/1/2014 |
| An essential role of CK2alpha in the mammalian circadian clock. | An in vitro ES cell-based clock recapitulation assay model identifies CK2α as an endogenous clock regulator.
Umemura Y, Yoshida J, Wada M, Tsuchiya Y, Minami Y, Watanabe H, Kondoh G, Takeda J, Inokawa H, Horie K, Yagita K., Free PMC Article | 01/25/2014 |
| receptor beta and its domains interact with casein kinase 2, phosphokinase C, and N-myristoylation sites of mitochondrial and nuclear proteins in mouse brain | Estrogen receptor β and its domains interact with casein kinase 2, phosphokinase C, and N-myristoylation sites of mitochondrial and nuclear proteins in mouse brain.
Paramanik V, Thakur MK., Free PMC Article | 09/22/2012 |
| The overall phenotype found in CK2alpha (-/- ) mice, is described. | CK2α is essential for embryonic morphogenesis.
Dominguez I, Degano IR, Chea K, Cha J, Toselli P, Seldin DC., Free PMC Article | 03/3/2012 |
| CK2alpha levels are predominant in comparison to CK2alpha' levels throughout the mammalian brain. | Predominance of CK2α over CK2α' in the mammalian brain.
Ceglia I, Flajolet M, Rebholz H. | 03/3/2012 |
| These experiments demonstrate that combined loss of one CK2alpha allele and both CK2alpha' alleles leads to unique abnormalities of growth and development. | Developmental and growth defects in mice with combined deficiency of CK2 catalytic genes.
Landesman-Bollag E, Belkina A, Hovey B, Connors E, Cox C, Seldin DC., Free PMC Article | 03/3/2012 |
| TNP1 is a newly identified binding partner of the alpha-subunit of casein kinase 2. | Protein kinase CK2 and new binding partners during spermatogenesis.
Mannowetz N, Kartarius S, Wennemuth G, Montenarh M., Free PMC Article | 11/27/2010 |
| CAPS activity in priming vesicle exocytosis requires CK2 phosphorylation | CAPS activity in priming vesicle exocytosis requires CK2 phosphorylation.
Nojiri M, Loyet KM, Klenchin VA, Kabachinski G, Martin TF., Free PMC Article | 01/21/2010 |
| reversible phosphorylation of CK2alpha requires precise regulation to allow proper mitotic progression | Evidence for regulation of mitotic progression through temporal phosphorylation and dephosphorylation of CK2alpha.
St-Denis NA, Derksen DR, Litchfield DW., Free PMC Article | 01/21/2010 |
| The balance between beta-arr and CK1/2 determines whether WNT/RAC-1 or other non-canonical WNT pathways are activated. | Beta-arrestin and casein kinase 1/2 define distinct branches of non-canonical WNT signalling pathways.
Bryja V, Schambony A, Cajánek L, Dominguez I, Arenas E, Schulte G., Free PMC Article | 01/21/2010 |