Synergistic antitumor activity by dual blockade of CCR1 and CXCR2 expressed on myeloid cells within the tumor microenvironment.
Masui H, Kawada K, Itatani Y, Hirai H, Nakanishi Y, Kiyasu Y, Hanada K, Okamoto M, Hirata W, Nishikawa Y, Sugimoto N, Tamura T, Sakai Y, Obama K., Free PMC Article

CXCR2, as a key regulatory gene of HDP-PG-1, maintains intestinal mucosal homeostasis.
Yan D, Wei G, Ai Z, Song S, Zhang L, Dong N, Dou X, Shan A.

CXCL1-CXCR2 axis mediates inflammatory response after sciatic nerve injury by regulating macrophage infiltration.
Jiang S, Li W, Song M, Liang J, Liu G, Du Q, Wang L, Meng H, Tang L, Yang Y, Zhang B.

CXCL5 activates CXCR2 in nociceptive sensory neurons to drive joint pain and inflammation in experimental gouty arthritis.
Yin C, Liu B, Dong Z, Shi S, Peng C, Pan Y, Bi X, Nie H, Zhang Y, Tai Y, Hu Q, Wang X, Shao X, An H, Fang J, Wang C, Liu B., Free PMC Article

Endothelial CXCR2 deficiency attenuates renal inflammation and glycocalyx shedding through NF-κB signaling in diabetic kidney disease.
Cui S, Chen X, Li J, Wang W, Meng D, Zhu S, Shen S., Free PMC Article

Increased expression of CXCL6 in secretory cells drives fibroblast collagen synthesis and is associated with increased mortality in idiopathic pulmonary fibrosis.
Bahudhanapati H, Tan J, Apel RM, Seeliger B, Schupp J, Li X, Sullivan DI, Sembrat J, Rojas M, Tabib T, Valenzi E, Lafyatis R, Mitash N, Hernandez Pineda R, Jawale C, Peroumal D, Biswas P, Tedrow J, Adams T, Kaminski N, Wuyts WA, McDyer JF, Gibson KF, Alder JK, Königshoff M, Zhang Y, Nouraie M, Prasse A, Kass DJ.

Exercise training inhibits macrophage-derived IL-17A-CXCL5-CXCR2 inflammatory axis to attenuate pulmonary fibrosis in mice exposed to silica.
Jin F, Li Y, Gao X, Yang X, Li T, Liu S, Wei Z, Li S, Mao N, Liu H, Cai W, Xu H, Zhang H.

CXCR2 antagonism attenuates neuroinflammation after subarachnoid hemorrhage.
Luo X.

CXCR2 Is Deregulated in ALS Spinal Cord and Its Activation Triggers Apoptosis in Motor Neuron-Like Cells Overexpressing hSOD1-G93A.
La Cognata V, D'Amico AG, Maugeri G, Morello G, Guarnaccia M, Magrì B, Aronica E, D'Agata V, Cavallaro S., Free PMC Article

CXCR2 expression during melanoma tumorigenesis controls transcriptional programs that facilitate tumor growth.
Yang J, Bergdorf K, Yan C, Luo W, Chen SC, Ayers GD, Liu Q, Liu X, Boothby M, Weiss VL, Groves SM, Oleskie AN, Zhang X, Maeda DY, Zebala JA, Quaranta V, Richmond A., Free PMC Article

Tumor-associated macrophages mediate gastrointestinal stromal tumor cell metastasis through CXCL2/CXCR2.
Cai H, Chen Y, Chen X, Sun W, Li Y.

CXCL1/CXCR2 is involved in white matter injury in neonatal rats via the gut-brain axis.
Yang C, Feng Z, Deng H, Dai L, He L, Yin L, Zhao J., Free PMC Article

CXCR2 intrinsically drives the maturation and function of neutrophils in mice.
Delobel P, Ginter B, Rubio E, Balabanian K, Lazennec G., Free PMC Article

CXCL1-CXCR2 signalling mediates hypertensive retinopathy by inducing macrophage infiltration.
Wang S, Bai J, Zhang YL, Lin QY, Han X, Qu WK, Zhang PF, Ge YS, Zhao Q, Li HH., Free PMC Article

Senescent hepatic stellate cells promote liver regeneration through IL-6 and ligands of CXCR2.
Cheng N, Kim KH, Lau LF., Free PMC Article

C-X-C motif chemokine ligand 1 and its receptor C-X-C motif chemokine receptor 2 in trigeminal ganglion contribute to nerve injury-induced orofacial mechanical allodynia.
Yang J, Liu F, Zhang YY, Lin J, Li YL, Zhou C, Li CJ, Shen JF.

CXCR1/2 Inhibitor Ladarixin Ameliorates the Insulin Resistance of 3T3-L1 Adipocytes by Inhibiting Inflammation and Improving Insulin Signaling.
Castelli V, Brandolini L, d'Angelo M, Giorgio C, Alfonsetti M, Cocchiaro P, Lombardi F, Cimini A, Allegretti M., Free PMC Article

Nintedanib Regulates GRK2 and CXCR2 to Reduce Neutrophil Recruitment in Endotoxin-Induced Lung Injury.
Su VY, Chen WC, Yu WK, Wu HH, Chen H, Yang KY., Free PMC Article

CXCL5/CXCR2 modulates inflammation-mediated neural repair after optic nerve injury.
Liu YF, Liang JJ, Ng TK, Hu Z, Xu C, Chen S, Chen SL, Xu Y, Zhuang X, Huang S, Zhang M, Pang CP, Cen LP.

GSDMD contributes to host defence against Staphylococcus aureus skin infection by suppressing the Cxcl1-Cxcr2 axis.
Liu ZZ, Yang YJ, Zhou FH, Ma K, Lin XQ, Yan SQ, Gao Y, Chen W., Free PMC Article

Astrocytes lure CXCR2-expressing CD4(+) T cells to gray matter via TAK1-mediated chemokine production in a mouse model of multiple sclerosis.
Khaw YM, Tierney A, Cunningham C, Soto-Díaz K, Kang E, Steelman AJ, Inoue M., Free PMC Article

Leptin Receptor q223r Polymorphism Influences Clostridioides difficile Infection-Induced Neutrophil CXCR2 Expression in an Interleukin-1β Dependent Manner.
Horrigan O, Jose S, Mukherjee A, Sharma D, Huber A, Madan R., Free PMC Article

Neutrophil recruitment by chemokines Cxcl1/KC and Cxcl2/MIP2: Role of Cxcr2 activation and glycosaminoglycan interactions.
Sawant KV, Sepuru KM, Lowry E, Penaranda B, Frevert CW, Garofalo RP, Rajarathnam K., Free PMC Article

Host Cxcr2-Dependent Regulation of Pancreatic Cancer Growth, Angiogenesis, and Metastasis.
Purohit A, Saxena S, Varney M, Prajapati DR, Kozel JA, Lazenby A, Singh RK., Free PMC Article

Chemokine Receptor CXCR-2 Initiates Atrial Fibrillation by Triggering Monocyte Mobilization in Mice.
Zhang YL, Cao HJ, Han X, Teng F, Chen C, Yang J, Yan X, Li PB, Liu Y, Xia YL, Guo SB, Li HH.