| TMIGD2 as a potential therapeutic target in glioma patients. | TMIGD2 as a potential therapeutic target in glioma patients.
Boulhen C, Ait Ssi S, Benthami H, Razzouki I, Lakhdar A, Karkouri M, Badou A., Free PMC Article | 06/7/2023 |
| KIR3DL3-HHLA2 and TMIGD2-HHLA2 pathways: The dual role of HHLA2 in immune responses and its potential therapeutic approach for cancer immunotherapy. | KIR3DL3-HHLA2 and TMIGD2-HHLA2 pathways: The dual role of HHLA2 in immune responses and its potential therapeutic approach for cancer immunotherapy.
Li Y, Lv C, Yu Y, Wu B, Zhang Y, Lang Q, Liang Z, Zhong C, Shi Y, Han S, Xu F, Tian Y., Free PMC Article | 05/4/2023 |
| HHLA2 Activates the JAK/STAT Signaling Pathway by Binding to TMIGD2 in Hepatocellular Carcinoma Cells. | HHLA2 Activates the JAK/STAT Signaling Pathway by Binding to TMIGD2 in Hepatocellular Carcinoma Cells.
Guo H, Zhang C, Tang X, Zhang T, Liu Y, Yu H, Li Y, Wang R. | 06/18/2022 |
| NEDD4 regulates ubiquitination and stability of the cell adhesion molecule IGPR-1 via lysosomal pathway. | NEDD4 regulates ubiquitination and stability of the cell adhesion molecule IGPR-1 via lysosomal pathway.
Sun L, Amraei R, Rahimi N., Free PMC Article | 10/2/2021 |
| Overexpression of B7H5/CD28H is associated with worse survival in human gastric cancer. | Overexpression of B7H5/CD28H is associated with worse survival in human gastric cancer.
Hu C, Xu Z, Chen S, Lv H, Wang Y, Wang X, Mo S, Shi C, Wei S, Hu L, Chen W, Cheng X., Free PMC Article | 05/15/2021 |
| Cell adhesion molecule IGPR-1 activates AMPK connecting cell adhesion to autophagy. | Cell adhesion molecule IGPR-1 activates AMPK connecting cell adhesion to autophagy.
Amraei R, Alwani T, Ho RX, Aryan Z, Wang S, Rahimi N., Free PMC Article | 05/8/2021 |
| VISTA protein (B7-H5) is a ligand for transmembrane and immunoglobulin domain containing 2 protein (CD28H) and is widely expressed in tumor cells. B7-H5 expression is closely related to the prognosis of the tumor [Review]. | Phenotypical and potential functional characteristics of different immune cells expressing CD28H/B7-H5 and their relationship with cancer prognosis.
Zhong C, Lang Q, Yu J, Wu S, Xu F, Tian Y., Free PMC Article | 08/1/2020 |
| Findings indicate that IGPR-1 is an important player in endothelial cell mechanosensing, insights that have important implications for the pathogenesis of common maladies, including ischemic heart diseases and inflammation. | The cell adhesion molecule IGPR-1 is activated by and regulates responses of endothelial cells to shear stress.
Ho RX, Tahboub R, Amraei R, Meyer RD, Varongchayakul N, Grinstaff M, Rahimi N., Free PMC Article | 05/16/2020 |
| High TMIGD2 expression levels in oral squamous cell carcinoma cells indicate poor prognosis. TMIGD2 expression inversely correlated with the TIM3, LAG3, and B7H3 levels. | The Expression Patterns and Associated Clinical Parameters of Human Endogenous Retrovirus-H Long Terminal Repeat-Associating Protein 2 and Transmembrane and Immunoglobulin Domain Containing 2 in Oral Squamous Cell Carcinoma.
Xiao Y, Li H, Yang LL, Mao L, Wu CC, Zhang WF, Sun ZJ., Free PMC Article | 08/31/2019 |
| B7-H5/CD28H is a co-stimulatory signal pathway, and expression of B7-H5 is associated with improved disease prognosis in patients with pancreatic cancer. | B7-H5/CD28H is a co-stimulatory pathway and correlates with improved prognosis in pancreatic ductal adenocarcinoma.
Chen Q, Wang J, Chen W, Zhang Q, Wei T, Zhou Y, Xu X, Bai X, Liang T., Free PMC Article | 02/16/2019 |
| The authors demonstrate that IGPR-1 is localized to endothelial adherens junctions and, through trans-homophilic dimerization, regulates endothelial cell-cell adhesion and barrier function. | IGPR-1 Is Required for Endothelial Cell-Cell Adhesion and Barrier Function.
Wang YHW, Meyer RD, Bondzie PA, Jiang Y, Rahimi I, Rezazadeh K, Mehta M, Laver NMV, Costello CE, Rahimi N., Free PMC Article | 07/1/2017 |
| B7 homologue 5 (B7-H5), was identified as a specific ligand for CD28H. | B7-H5 costimulates human T cells via CD28H.
Zhu Y, Yao S, Iliopoulou BP, Han X, Augustine MM, Xu H, Phennicie RT, Flies SJ, Broadwater M, Ruff W, Taube JM, Zheng L, Luo L, Zhu G, Chen J, Chen L., Free PMC Article | 02/22/2016 |
| Authors identified IGPR-1, also called TMIGD2, gene as a novel cell adhesion receptor that is expressed in various human organs and tissues, mainly in cells with epithelium and endothelium origins. | Identification of IGPR-1 as a novel adhesion molecule involved in angiogenesis.
Rahimi N, Rezazadeh K, Mahoney JE, Hartsough E, Meyer RD., Free PMC Article | 11/24/2012 |