| CDYL reinforces male gonadal sex determination through epigenetically repressing Wnt4 transcription in mice. | CDYL reinforces male gonadal sex determination through epigenetically repressing Wnt4 transcription in mice.
Okashita N, Maeda R, Tachibana M., Free PMC Article | 05/13/2023 |
| Nuclear Condensation of CDYL Links Histone Crotonylation and Cystogenesis in Autosomal Dominant Polycystic Kidney Disease. | Nuclear Condensation of CDYL Links Histone Crotonylation and Cystogenesis in Autosomal Dominant Polycystic Kidney Disease.
Dang L, Cao X, Zhang T, Sun Y, Tian S, Gong T, Xiong H, Cao P, Li Y, Yu S, Yang L, Zhang L, Liu T, Zhang K, Liang J, Chen Y., Free PMC Article | 01/21/2023 |
| Disruption of Cdyl gene impairs mouse lung epithelium differentiation and maturation. | Disruption of Cdyl gene impairs mouse lung epithelium differentiation and maturation.
Wan L, Hu X, Xia T, Li F, Chi Q, Ma H, Yan S, Li W, Huang W. | 01/7/2023 |
| Cdyl Deficiency Brakes Neuronal Excitability and Nociception through Promoting Kcnb1 Transcription in Peripheral Sensory Neurons. | Cdyl Deficiency Brakes Neuronal Excitability and Nociception through Promoting Kcnb1 Transcription in Peripheral Sensory Neurons.
Sun ZW, Waybright JM, Beldar S, Chen L, Foley CA, Norris-Drouin JL, Lyu TJ, Dong A, Min J, Wang YP, James LI, Wang Y., Free PMC Article | 04/16/2022 |
| Circular RNA (circRNA) CDYL Induces Myocardial Regeneration by ceRNA After Myocardial Infarction. | Circular RNA (circRNA) CDYL Induces Myocardial Regeneration by ceRNA After Myocardial Infarction.
Zhang M, Wang Z, Cheng Q, Wang Z, Lv X, Wang Z, Li N., Free PMC Article | 02/20/2021 |
| Cdyl is crucial for spermatogenesis and male fertility, which provides novel insights into the function of CDY gene, as well as the pathogenesis of Y chromosome microdeletion-related reproductive failure. | Germline deletion of Cdyl causes teratozoospermia and progressive infertility in male mice.
Xia X, Zhou X, Quan Y, Hu Y, Xing F, Li Z, Xu B, Xu C, Zhang A., Free PMC Article | 05/23/2020 |
| results demonstrate that CDYL-mediated histone crotonylation plays a critical role in regulating stress-induced depression. | Chromodomain Y-like Protein-Mediated Histone Crotonylation Regulates Stress-Induced Depressive Behaviors.
Liu Y, Li M, Fan M, Song Y, Yu H, Zhi X, Xiao K, Lai S, Zhang J, Jin X, Shang Y, Liang J, Huang Z. | 02/22/2020 |
| These results demonstrate that CDYL is a regulator of neuronal migration and shed light on the pathogenesis of seizure-related neurodevelopmental disorders. | CDYL Deficiency Disrupts Neuronal Migration and Increases Susceptibility to Epilepsy.
Qin R, Cao S, Lyu T, Qi C, Zhang W, Wang Y. | 11/25/2017 |
| CDYL negatively regulates histone crotonylation by acting as a crotonyl-CoA hydratase to convert crotonyl-CoA to beta-hydroxybutyryl-CoA and suggest role in spermatogenesis. | Chromodomain Protein CDYL Acts as a Crotonyl-CoA Hydratase to Regulate Histone Crotonylation and Spermatogenesis.
Liu S, Yu H, Liu Y, Liu X, Zhang Y, Bu C, Yuan S, Chen Z, Xie G, Li W, Xu B, Yang J, He L, Jin T, Xiong Y, Sun L, Liu X, Han C, Cheng Z, Liang J, Shang Y. | 09/30/2017 |
| A combination of H3K9me2 and H3K27me3 recruits Cdyl to the inactivated X chromosome, and this, in turn, may facilitate propagation of the H3K9me2 mark by anchoring G9a. | Cdyl, a new partner of the inactive X chromosome and potential reader of H3K27me3 and H3K9me2.
Escamilla-Del-Arenal M, da Rocha ST, Spruijt CG, Masui O, Renaud O, Smits AH, Margueron R, Vermeulen M, Heard E., Free PMC Article | 02/1/2014 |
| The results of this study provided some insight into the molecular function of the Cdyl gene, showing that it inhibited the neuronal differentiation of iPS cells. | Generation and neuronal differentiation of induced pluripotent stem cells in Cdyl-/- mice.
Wan L, Hu XJ, Yan SX, Chen F, Cai B, Zhang XM, Wang T, Yu XB, Xiang AP, Li WQ. | 08/31/2013 |
| Cdyl may participate in the global chromatin remodelling that occurs in spermatogenesis. | Cdyl: a new transcriptional co-repressor.
Caron C, Pivot-Pajot C, van Grunsven LA, Col E, Lestrat C, Rousseaux S, Khochbin S., Free PMC Article | 01/21/2010 |