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    Cd38 CD38 antigen [ Mus musculus (house mouse) ]

    Gene ID: 12494, updated on 28-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    CD38 Deficiency Protects Mouse Retinal Ganglion Cells Through Activating the NAD+/Sirt1 Pathway in Ischemia-Reperfusion and Optic Nerve Crush Models.

    CD38 Deficiency Protects Mouse Retinal Ganglion Cells Through Activating the NAD+/Sirt1 Pathway in Ischemia-Reperfusion and Optic Nerve Crush Models.
    Pang Y, Hu H, Xu K, Cao T, Wang Z, Nie J, Zheng H, Luo H, Wang F, Xiong C, Deng KY, Xin HB, Zhang X., Free PMC Article

    05/29/2024
    Smooth-Muscle-Cell-Specific Deletion of CD38 Protects Mice from AngII-Induced Abdominal Aortic Aneurysm through Inhibiting Vascular Remodeling.

    Smooth-Muscle-Cell-Specific Deletion of CD38 Protects Mice from AngII-Induced Abdominal Aortic Aneurysm through Inhibiting Vascular Remodeling.
    Yu ZP, Wang YK, Wang XY, Gong LN, Tan HL, Jiang MX, Wang LF, Yu GH, Deng KY, Xin HB., Free PMC Article

    05/20/2024
    CD38 promotes hematopoietic stem cell dormancy.

    CD38 promotes hematopoietic stem cell dormancy.
    Ibneeva L, Singh SP, Sinha A, Eski SE, Wehner R, Rupp L, Kovtun I, Pérez-Valencia JA, Gerbaulet A, Reinhardt S, Wobus M, von Bonin M, Sancho J, Lund F, Dahl A, Schmitz M, Bornhäuser M, Chavakis T, Wielockx B, Grinenko T., Free PMC Article

    03/29/2024
    Retention of stress susceptibility in the mdx mouse model of Duchenne muscular dystrophy after PGC-1alpha overexpression or ablation of IDO1 or CD38.

    Retention of stress susceptibility in the mdx mouse model of Duchenne muscular dystrophy after PGC-1α overexpression or ablation of IDO1 or CD38.
    Johnson EE, Southern WM, Doud B, Steiger B, Razzoli M, Bartolomucci A, Ervasti JM.,

    03/25/2024
    CD38 deficient mice are not protected from atherosclerosis.

    CD38 deficient mice are not protected from atherosclerosis.
    Kong XY, Lauritzen KH, Dahl TB, Holm S, Olsen MB, Skjelland M, Nielsen C, Michelsen AE, Ueland T, Aukrust P, Halvorsen B, Sandanger Ø.

    03/20/2024
    The NADase CD38 may not dictate NAD levels in brain mitochondria of aged mice but regulates hydrogen peroxide generation.

    The NADase CD38 may not dictate NAD levels in brain mitochondria of aged mice but regulates hydrogen peroxide generation.
    Camacho-Pereira J, Lai de Souza LO, Chichierchio MS, Rodrigues-Chaves C, Lomba LS, Fonseca-Oliveira M, Carvalho-Mendonça D, Silva-Rodrigues T, Galina A.

    03/20/2024
    NADase CD38 is a key determinant of ovarian aging.

    NADase CD38 is a key determinant of ovarian aging.
    Yang Q, Chen W, Cong L, Wang M, Li H, Wang H, Luo X, Zhu J, Zeng X, Zhu Z, Xu Y, Lei M, Zhao Y, Wei C, Sun Y., Free PMC Article

    02/2/2024
    The role of CD38 in inflammation-induced depression-like behavior and the antidepressant effect of (R)-ketamine.

    The role of CD38 in inflammation-induced depression-like behavior and the antidepressant effect of (R)-ketamine.
    Zhang X, He T, Wu Z, Wang Y, Liu H, Zhang B, Yang S, Wang D, Huang C, Duan J, Xu X, Xu X, Hashimoto K, Jiang R, Yang L, Yang C.

    12/20/2023
    CD38 Deficiency Alleviates Diabetic Cardiomyopathy by Coordinately Inhibiting Pyroptosis and Apoptosis.

    CD38 Deficiency Alleviates Diabetic Cardiomyopathy by Coordinately Inhibiting Pyroptosis and Apoptosis.
    Wang LF, Li Q, Wen K, Zhao QH, Zhang YT, Zhao JL, Ding Q, Guan XH, Xiao YF, Deng KY, Xin HB., Free PMC Article

    11/18/2023
    CD38 deficiency promotes skeletal muscle and brown adipose tissue energy expenditure through activating NAD[+]-Sirt1-PGC1alpha signaling pathway.

    CD38 deficiency promotes skeletal muscle and brown adipose tissue energy expenditure through activating NAD(+)-Sirt1-PGC1α signaling pathway.
    Ding Q, Wen K, Li Q, Zhao QH, Zhao JL, Xiao YF, Guan XH, Jiang MX, Zhang F, Wang LF.

    07/4/2023
    Cell-Intrinsic CD38 Expression Sustains Exhausted CD8[+] T Cells by Regulating Their Survival and Metabolism during Chronic Viral Infection.

    Cell-Intrinsic CD38 Expression Sustains Exhausted CD8(+) T Cells by Regulating Their Survival and Metabolism during Chronic Viral Infection.
    DeRogatis JM, Neubert EN, Viramontes KM, Henriquez ML, Nicholas DA, Tinoco R., Free PMC Article

    05/19/2023
    Oxidative degradation of dihydrofolate reductase increases CD38-mediated ferroptosis susceptibility.

    Oxidative degradation of dihydrofolate reductase increases CD38-mediated ferroptosis susceptibility.
    Ma Y, Yi M, Wang W, Liu X, Wang Q, Liu C, Chen Y, Deng H., Free PMC Article

    11/19/2022
    CD38 Mediates Lung Fibrosis by Promoting Alveolar Epithelial Cell Aging.

    CD38 Mediates Lung Fibrosis by Promoting Alveolar Epithelial Cell Aging.
    Cui H, Xie N, Banerjee S, Dey T, Liu RM, Antony VB, Sanders YY, Adams TS, Gomez JL, Thannickal VJ, Kaminski N, Liu G.

    08/27/2022
    CD38 deficiency protects the retina from ischaemia/reperfusion injury partly via suppression of TLR4/MyD88/NF-kappaB signalling.

    CD38 deficiency protects the retina from ischaemia/reperfusion injury partly via suppression of TLR4/MyD88/NF-κB signalling.
    Chen G, Yan F, Wei W, Wang F, Wang Z, Nie J, Jin M, Pang Y, Qin M, Wang L, Zhang X.

    06/11/2022
    CD38 plays an age-related role in cholinergic deregulation of airway smooth muscle contractility.

    CD38 plays an age-related role in cholinergic deregulation of airway smooth muscle contractility.
    Bai Y, Guedes AGP, Krishnan R, Ai X., Free PMC Article

    05/14/2022
    CD38 Drives Progress of Osteoarthritis by Affecting Cartilage Homeostasis.

    CD38 Drives Progress of Osteoarthritis by Affecting Cartilage Homeostasis.
    Ma JJ, Ying J, Wang JY, Xu TT, Xia HT, Jin HT, Xiao LW, Shang WJ, Wang WQ, Feng JY., Free PMC Article

    05/14/2022
    CD38 deficiency up-regulated IL-1beta and MCP-1 through TLR4/ERK/NF-kappaB pathway in sepsis pulmonary injury.

    CD38 deficiency up-regulated IL-1β and MCP-1 through TLR4/ERK/NF-κB pathway in sepsis pulmonary injury.
    Du Y, Zhang H, Guo Y, Song K, Zeng L, Chen Y, Xie Z, Li R.

    04/30/2022
    Benefits in cardiac function by CD38 suppression: Improvement in NAD(+) levels, exercise capacity, heart rate variability and protection against catecholamine-induced ventricular arrhythmias.

    Benefits in cardiac function by CD38 suppression: Improvement in NAD(+) levels, exercise capacity, heart rate variability and protection against catecholamine-induced ventricular arrhythmias.
    Agorrody G, Peclat TR, Peluso G, Gonano LA, Santos L, van Schooten W, Chini CCS, Escande C, Chini EN, Contreras P., Free PMC Article

    04/30/2022
    CD38 deficiency alleviates Ang II-induced vascular remodeling by inhibiting small extracellular vesicle-mediated vascular smooth muscle cell senescence in mice.

    CD38 deficiency alleviates Ang II-induced vascular remodeling by inhibiting small extracellular vesicle-mediated vascular smooth muscle cell senescence in mice.
    Gan L, Liu D, Liu J, Chen E, Chen C, Liu L, Hu H, Guan X, Ma W, Zhang Y, He Y, Liu B, Tang S, Jiang W, Xue J, Xin H., Free PMC Article

    03/12/2022
    CD38-mediated Inhibition of Bruton's Tyrosine Kinase in Macrophages Prevents Endotoxemic Lung Injury.

    CD38-mediated Inhibition of Bruton's Tyrosine Kinase in Macrophages Prevents Endotoxemic Lung Injury.
    Farahany J, Tsukasaki Y, Mukhopadhyay A, Mittal M, Nepal S, Tiruppathi C, Malik AB., Free PMC Article

    02/19/2022
    CD38 Correlates with an Immunosuppressive Treg Phenotype in Lupus-Prone Mice.

    CD38 Correlates with an Immunosuppressive Treg Phenotype in Lupus-Prone Mice.
    Pérez-Lara JC, Espinosa E, Santos-Argumedo L, Romero-Ramírez H, López-Herrera G, García-García F, Sandoval-Montes C, Ortiz-Navarrete V, Flores-Muñoz M, Rodríguez-Alba JC., Free PMC Article

    01/8/2022
    CD38 Deficiency Ameliorates Chronic Graft-Versus-Host Disease Murine Lupus via a B-Cell-Dependent Mechanism.

    CD38 Deficiency Ameliorates Chronic Graft-Versus-Host Disease Murine Lupus via a B-Cell-Dependent Mechanism.
    Martínez-Blanco Á, Domínguez-Pantoja M, Botía-Sánchez M, Pérez-Cabrera S, Bello-Iglesias N, Carrillo-Rodríguez P, Martin-Morales N, Lario-Simón A, Pérez-Sánchez-Cañete MM, Montosa-Hidalgo L, Guerrero-Fernández S, Longobardo-Polanco VM, Redondo-Sánchez S, Cornet-Gomez A, Torres-Sáez M, Fernández-Ibáñez A, Terrón-Camero L, Andrés-León E, O'Valle F, Merino R, Zubiaur M, Sancho J., Free PMC Article

    12/25/2021
    Critical Role of Astrocyte NAD(+) Glycohydrolase in Myelin Injury and Regeneration.

    Critical Role of Astrocyte NAD(+) Glycohydrolase in Myelin Injury and Regeneration.
    Langley MR, Choi CI, Peclat TR, Guo Y, Simon WL, Yoon H, Kleppe L, Lucchinetti CF, Chini CCS, Chini EN, Scarisbrick IA., Free PMC Article

    11/27/2021
    Intermittent Hypoxia Upregulates the Renin and Cd38 mRNAs in Renin-Producing Cells via the Downregulation of miR-203.

    Intermittent Hypoxia Upregulates the Renin and Cd38 mRNAs in Renin-Producing Cells via the Downregulation of miR-203.
    Takeda Y, Itaya-Hironaka A, Yamauchi A, Makino M, Sakuramoto-Tsuchida S, Ota H, Kawaguchi R, Takasawa S., Free PMC Article

    10/30/2021
    CD38 downregulation modulates NAD(+) and NADP(H) levels in thermogenic adipose tissues.

    CD38 downregulation modulates NAD(+) and NADP(H) levels in thermogenic adipose tissues.
    Benzi A, Sturla L, Heine M, Fischer AW, Spinelli S, Magnone M, Sociali G, Parodi A, Fenoglio D, Emionite L, Koch-Nolte F, Mittrücker HW, Guse AH, De Flora A, Zocchi E, Heeren J, Bruzzone S.

    04/17/2021
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