| Polymorphic estrogen receptor binding site causes Cd2-dependent sex bias in the susceptibility to autoimmune diseases. | Polymorphic estrogen receptor binding site causes Cd2-dependent sex bias in the susceptibility to autoimmune diseases.
Fernandez Lahore G, Förster M, Johannesson M, Sabatier P, Lönnblom E, Aoun M, He Y, Nandakumar KS, Zubarev RA, Holmdahl R., Free PMC Article | 10/23/2021 |
| CD2 is a surface marker for mouse and rat spermatogonial stem cells. | CD2 is a surface marker for mouse and rat spermatogonial stem cells.
Kanatsu-Shinohara M, Chen G, Morimoto H, Shinohara T., Free PMC Article | 07/3/2021 |
| CD2 Regulates Pathogenesis of Asthma Induced by House Dust Mice Extract. | CD2 Regulates Pathogenesis of Asthma Induced by House Dust Mice Extract.
Hashem T, Kammala AK, Thaxton K, Griffin RM, Mullany K, Panettieri RA Jr, Subramanian H, Das R., Free PMC Article | 04/13/2021 |
| Ptpn22 and Cd2 Variations Are Associated with Altered Protein Expression and Susceptibility to Type 1 Diabetes | Ptpn22 and Cd2 Variations Are Associated with Altered Protein Expression and Susceptibility to Type 1 Diabetes in Nonobese Diabetic Mice.
Fraser HI, Howlett S, Clark J, Rainbow DB, Stanford SM, Wu DJ, Hsieh YW, Maine CJ, Christensen M, Kuchroo V, Sherman LA, Podolin PL, Todd JA, Steward CA, Peterson LB, Bottini N, Wicker LS., Free PMC Article | 02/27/2016 |
| CD2 stimuli were mandatory for Treg cell survival with reduced Bim expression, but CD2 may not function as a direct receptor for molecules on stromal cells. | CD2-mediated regulation of peripheral CD4(+) CD25(+) regulatory T-cell apoptosis accompanied by down-regulation of Bim.
Kashiwakura Y, Sakurai D, Kanno Y, Hashiguchi M, Kobayashi A, Kurosu A, Tokudome S, Kobata T, Kojima H., Free PMC Article | 06/8/2013 |
| CD244 inhibition and activation depends on CD2 and phospholipase C-gamma1 | Inhibition and activation by CD244 depends on CD2 and phospholipase C-gamma1.
Clarkson NG, Brown MH., Free PMC Article | 01/21/2010 |
| nanoscale increases in CD2-CD48-mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse | Nanoscale increases in CD2-CD48-mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse.
Milstein O, Tseng SY, Starr T, Llodra J, Nans A, Liu M, Wild MK, van der Merwe PA, Stokes DL, Reisner Y, Dustin ML., Free PMC Article | 01/21/2010 |
| CD2 deficient mice are more resistant to T. gondii infection than wild type mice | CD2 deficiency partially prevents small bowel inflammation and improves parasite control in murine Toxoplasma gondii infection.
Pawlowski NN, Struck D, Grollich K, Kuhl AA, Zeitz M, Liesenfeld O, Hoffmann JC., Free PMC Article | 01/21/2010 |
| This antigen is a dominant target for heart allograft responses. | CD2 is a dominant target for allogeneic responses.
Bai Y, Fu S, Honig S, Wang Y, Qin L, Chen D, Bromberg JS. | 01/21/2010 |
| Analysis of the ligand-receptor pairs involved in induction of germline transcripts (Igamma2a) necessary for switch recombination revealed that expression of CD48 on B cells and ligands CD2 and CD244 on NK cells are able to stimulate Igamma2a | Receptors and counterreceptors involved in NK-B cell interactions.
Gao N, Dang T, Dunnick WA, Collins JT, Blazar BR, Yuan D. | 01/21/2010 |
| CD2 is important for the efficient development of CD4 single-positive thymocytes and TCR-dependent activation of mature CD4 lymph node T cells, but does not direct a particular helper T cell subset polarity. | CD2 facilitates differentiation of CD4 Th cells without affecting Th1/Th2 polarization.
Sasada T, Yang H, Reinherz EL. | 01/21/2010 |
| autoimmunity may be mediated by a combination of genes in the SLAM/CD2 family cluster | Association of extensive polymorphisms in the SLAM/CD2 gene cluster with murine lupus.
Wandstrat AE, Nguyen C, Limaye N, Chan AY, Subramanian S, Tian XH, Yim YS, Pertsemlidis A, Garner HR Jr, Morel L, Wakeland EK. | 01/21/2010 |
| molecular mechanism of heterophilic adhesion between the murine T-cell adhesion glycoprotein CD2 and its ligand CD48 | Direct measurements of heterotypic adhesion between the cell surface proteins CD2 and CD48.
Zhu B, Davies EA, van der Merwe PA, Calvert T, Leckband DE. | 01/21/2010 |
| Despite normal T cell numbers, mice deficient in the costimulatory molecules CD2 and CD28 spontaneously develop Pneumocystis carinii pneumonia. | T cell costimulatory molecule function determines susceptibility to infection with Pneumocystis carinii in mice.
Beck JM, Blackmon MB, Rose CM, Kimzey SL, Preston AM, Green JM. | 01/21/2010 |