| Familial hypereosinophilia associated with eosinophilic gastrointestinal symptoms in individuals with a missense mutation in CKLF-like MARVEL transmembrane domain containing 3. | Familial hypereosinophilia associated with eosinophilic gastrointestinal symptoms in individuals with a missense mutation in CKLF-like MARVEL transmembrane domain containing 3.
Wardlaw AJ, Barwell J, Hitchman C, Shrine N, Bennett N, Adewoye A, Ozturk H, Ntereke T, Wurm P, Tobin M, Gooptu B, Hollox E, Wain LV. | 04/9/2022 |
| CMTM3 exhibited a lower expression pattern in gastric cancer tissues.MiR-135b-5p promotes gastric cancer progression by targeting CMTM3. | miR-135b-5p promotes gastric cancer progression by targeting CMTM3.
Lu M, Huang Y, Sun W, Li P, Li L, Li L. | 08/11/2018 |
| this study demonstrates that knockdown of CMTM3 promotes the metastasis of gastric cancer through the STAT3/Twist1/EMT pathway | Knockdown of CMTM3 promotes metastasis of gastric cancer via the STAT3/Twist1/EMT signaling pathway.
Yuan W, Li T, Mo X, Wang X, Liu B, Wang W, Su Y, Xu L, Han W., Free PMC Article | 12/23/2017 |
| CMTM3 was significantly hypermethylated in colorectal cancer tissues when compared with adjacent normal colorectal tissues. | DNA methylation of CMTM3, SSTR2, and MDFI genes in colorectal cancer.
Li J, Chen C, Bi X, Zhou C, Huang T, Ni C, Yang P, Chen S, Ye M, Duan S. | 09/23/2017 |
| CMTM3 decreases EGFR expression, facilitates EGFR degradation, and inhibits the EGF-mediated tumorigenicity of gastric cancer cells by enhancing Rab5 activity. | CMTM3 decreases EGFR expression and EGF-mediated tumorigenicity by promoting Rab5 activity in gastric cancer.
Yuan W, Liu B, Wang X, Li T, Xue H, Mo X, Yang S, Ding S, Han W. | 08/12/2017 |
| CMTM3 mediates cell-cell adhesion at adherens junctions and contributes to the control of vascular sprouting by regulation VE-cadherin turnover. | CMTM3 (CKLF-Like Marvel Transmembrane Domain 3) Mediates Angiogenesis by Regulating Cell Surface Availability of VE-Cadherin in Endothelial Adherens Junctions.
Chrifi I, Louzao-Martinez L, Brandt M, van Dijk CGM, Burgisser P, Zhu C, Kros JM, Duncker DJ, Cheng C. | 06/24/2017 |
| Overexpression of CMTM3 attenuated the tumor growth of hepatocellular carcinoma. | CKLF-Like MARVEL Transmembrane Domain-Containing Member 3 (CMTM3) Inhibits the Proliferation and Tumorigenisis in Hepatocellular Carcinoma Cells.
Li W, Zhang S., Free PMC Article | 03/18/2017 |
| identified CMTM3 as a novel secretory protein released via exosomes in the prostate | CMTM3 presents a secreted form released via exosomes.
Liu B, Li H, Fu W, Cheng Y, Yuan W, Liu W, Xue H, Mo X., Free PMC Article | 03/4/2017 |
| study indicates that elevated CMTM3 methylation is a risk factor in male LSCC patients, especially in the patients with age over 55years and with smoking behavior | Elevated methylation of CMTM3 promoter in the male laryngeal squamous cell carcinoma patients.
Shen Z, Chen X, Li Q, Zhou C, Xu Y, Yu R, Ye H, Li J, Duan S. | 02/18/2017 |
| Reduced expression of CMTM3 is associated with prostate cancer. | CMTM3 is reduced in prostate cancer and inhibits migration, invasion and growth of LNCaP cells.
Hu F, Yuan W, Wang X, Sheng Z, Yuan Y, Qin C, He C, Xu T. | 04/30/2016 |
| CMTM1 and 3 are priority targets in glioblastomas. First insights into signalling of these two genes that might be conveyed by growth factor receptor, Src family kinase and WNT activation was presented. | Systematic investigation of CMTM family genes suggests relevance to glioblastoma pathogenesis and CMTM1 and CMTM3 as priority targets.
Delic S, Thuy A, Schulze M, Proescholdt MA, Dietrich P, Bosserhoff AK, Riemenschneider MJ. | 02/6/2016 |
| Low expression of CMTM3 was associated with metastasis and recurrence of oral squamous cell carcinoma. | CMTM3 inhibits cell growth and migration and predicts favorable survival in oral squamous cell carcinoma.
Zhang H, Zhang J, Nan X, Li X, Qu J, Hong Y, Sun L, Chen Y, Li T. | 01/30/2016 |
| CMTM3 is significantly down-regulated in clear cell renal cell carcinoma and exerts remarkable tumor-suppressive functions | CMTM3 is frequently reduced in clear cell renal cell carcinoma and exhibits tumor suppressor activities.
Xie J, Yuan Y, Liu Z, Xiao Y, Zhang X, Qin C, Sheng Z, Xu T, Wang X. | 12/20/2014 |
| Peritoneal disseminated metastases were significantly suppressed by CMTM3. | CMTM3 inhibits cell migration and invasion and correlates with favorable prognosis in gastric cancer.
Su Y, Lin Y, Zhang L, Liu B, Yuan W, Mo X, Wang X, Li H, Xing X, Cheng X, Dong B, Hu Y, Du H, Zhu Y, Ding N, Li J, Liu W, Ma Y, Qiu X, Ji J, Han W., Free PMC Article | 07/5/2014 |
| CMTM3 inhibits prostate-specific antigen expression at both mRNA and protein levels with no obvious influence on androgen receptor expression. | CMTM3 can affect the transcription activity of androgen receptor and inhibit the expression level of PSA in LNCaP cells.
Wang Y, Li T, Qiu X, Mo X, Zhang Y, Song Q, Ma D, Han W. | 01/21/2010 |
| Bioinformatics based on CKLF2 cDNA and protein sequences in combination with experimental validation identified CKLFSF1-8 gene clusters, between the SCY and the TM4SF gene families. The 8 family members were cloned and characterized. | Identification of eight genes encoding chemokine-like factor superfamily members 1-8 (CKLFSF1-8) by in silico cloning and experimental validation.
Han W, Ding P, Xu M, Wang L, Rui M, Shi S, Liu Y, Zheng Y, Chen Y, Yang T, Ma D. | 01/21/2010 |
| CMTM3/CKLFSF3 is an evolutionarily conserved gene that may have important roles in the male reproductive system and immune system. | Characterization and expression profile of CMTM3/CKLFSF3.
Zhong J, Wang Y, Qiu X, Mo X, Liu Y, Li T, Song Q, Ma D, Han W. | 01/21/2010 |