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    CCR7 C-C motif chemokine receptor 7 [ Homo sapiens (human) ]

    Gene ID: 1236, updated on 12-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    C-C chemokine receptor type 7 (CCR7) regulates hepatic CD8 + T cell homeostasis and response to acute liver injury.

    C-C chemokine receptor type 7 (CCR7) regulates hepatic CD8 + T cell homeostasis and response to acute liver injury.
    Niemietz P, Peiseler M, Kohlhepp M, Horn P, Matchett K, Wang Y, Haas L, Zhang T, Bruneau A, Guillot A, Berger H, Liepelt A, Warzecha K, Demske C, Möckel D, Lammers T, Henderson N, Heymann F, Tacke F.

    10/31/2024
    C-C Chemokine Receptor 7 Promotes T-Cell Acute Lymphoblastic Leukemia Invasion of the Central Nervous System via beta2-Integrins.

    C-C Chemokine Receptor 7 Promotes T-Cell Acute Lymphoblastic Leukemia Invasion of the Central Nervous System via β2-Integrins.
    Cardona CI, Rodriguez A, Torres VC, Sanchez A, Torres A, Vazquez AE, Wagler AE, Brissette MA, Bill CA, Vines CM., Free PMC Article

    09/24/2024
    CCR7/DUSP1 signaling Axis mediates iCAF to regulates head and neck squamous cell carcinoma growth.

    CCR7/DUSP1 signaling Axis mediates iCAF to regulates head and neck squamous cell carcinoma growth.
    Gao J, Wang Z, Lin S, Tian Y, Wu H, Li Z, Liu F.

    08/31/2024
    CCL21-CCR7 signaling promotes microglia/macrophage recruitment and chemotherapy resistance in glioblastoma.

    CCL21-CCR7 signaling promotes microglia/macrophage recruitment and chemotherapy resistance in glioblastoma.
    Geraldo LH, Garcia C, Xu Y, Leser FS, Grimaldi I, de Camargo Magalhães ES, Dejaegher J, Solie L, Pereira CM, Correia AH, De Vleeschouwer S, Tavitian B, Canedo NHS, Mathivet T, Thomas JL, Eichmann A, Lima FRS., Free PMC Article

    06/22/2023
    CCL19/CCR7 drives regulatory T cell migration and indicates poor prognosis in gastric cancer.

    CCL19/CCR7 drives regulatory T cell migration and indicates poor prognosis in gastric cancer.
    Xu D, Liu X, Ke S, Guo Y, Zhu C, Cao H., Free PMC Article

    05/30/2023
    Effects of chemokine receptor CCR7 in the pathophysiology and clinical features of the immuno-inflammatory response in primary pterygium.

    Effects of chemokine receptor CCR7 in the pathophysiology and clinical features of the immuno-inflammatory response in primary pterygium.
    Wang T, Peng R, Ni H, Zhong L, Zhang H, Wang T, Cheng H, Bao T, Jia X, Ling S.

    05/8/2023
    Heparin Specifically Interacts with Basic BBXB Motifs of the Chemokine CCL21 to Define CCR7 Signaling.

    Heparin Specifically Interacts with Basic BBXB Motifs of the Chemokine CCL21 to Define CCR7 Signaling.
    Artinger M, Gerken OJ, Legler DF., Free PMC Article

    02/4/2023
    CCR7 alterations associated with inferior outcome of adult T-cell leukemia/lymphoma under mogamulizumab treatment.

    CCR7 alterations associated with inferior outcome of adult T-cell leukemia/lymphoma under mogamulizumab treatment.
    Sakamoto Y, Ishida T, Masaki A, Murase T, Ohtsuka E, Takeshita M, Muto R, Iwasaki H, Ito A, Kusumoto S, Nakano N, Tokunaga M, Yonekura K, Tashiro Y, Iida S, Utsunomiya A, Ueda R, Inagaki H., Free PMC Article

    12/24/2022
    Effects of let-7a microRNA and C-C chemokine receptor type 7 expression on cellular function and prognosis in esophageal squamous cell carcinoma.

    Effects of let-7a microRNA and C-C chemokine receptor type 7 expression on cellular function and prognosis in esophageal squamous cell carcinoma.
    Yura M, Fukuda K, Matsuda S, Irino T, Nakamura R, Kawakubo H, Takeuchi H, Kitagawa Y., Free PMC Article

    10/22/2022
    Genome-Wide Association Study for Idiopathic Ventricular Tachyarrhythmias Identifies Key Role of CCR7 and PKN2 in Calcium Homeostasis and Cardiac Rhythm Maintenance.

    Genome-Wide Association Study for Idiopathic Ventricular Tachyarrhythmias Identifies Key Role of CCR7 and PKN2 in Calcium Homeostasis and Cardiac Rhythm Maintenance.
    Fang C, Wang P, Yu D, Zhang X, Gou D, Liang L, Bai X, Xie W, Li H, Pu J, Yao Y, Wang B, Ren X, Ke T, Tu X, Xu C, Wang QK.

    10/22/2022
    EXPRESSION OF CHEMOKINE (C-C MOTIF) RECEPTOR 7 IN PROSTATE CANCER TISSUE OF YOUNG PATIENTS AND IN METASTATIC CANCER CELLS.

    EXPRESSION OF CHEMOKINE (C-C MOTIF) RECEPTOR 7 IN PROSTATE CANCER TISSUE OF YOUNG PATIENTS AND IN METASTATIC CANCER CELLS.
    Parra-Medina R, Payán-Gómez C, Acosta-Vega NL, Ramírez-Clavijo S.

    08/27/2022
    WGCNA and molecular docking reveal key hub genes and potential natural inhibitor in interstitial cystitis/bladder pain syndrome.

    WGCNA and molecular docking reveal key hub genes and potential natural inhibitor in interstitial cystitis/bladder pain syndrome.
    Li K, Lai C, Liu C, Li Z, Guo K, Xu K.

    08/6/2022
    CCR7 expression in CD19 chimeric antigen receptor-engineered natural killer cells improves migration toward CCL19-expressing lymphoma cells and increases tumor control in mice with human lymphoma.

    CCR7 expression in CD19 chimeric antigen receptor-engineered natural killer cells improves migration toward CCL19-expressing lymphoma cells and increases tumor control in mice with human lymphoma.
    Schomer NT, Jiang ZK, Lloyd MI, Klingemann H, Boissel L.

    07/30/2022
    Lack of DOCK8 impairs the primary biologic functions of human NK cells and abrogates CCR7 surface expression in a WASP-independent manner.

    Lack of DOCK8 impairs the primary biologic functions of human NK cells and abrogates CCR7 surface expression in a WASP-independent manner.
    Patrizi O, Baronio M, Gazzurelli L, Rossi S, Rezzola S, Marcenaro E, Plebani A, Badolato R, Parolini S, Lougaris V, Tabellini G.

    05/7/2022
    CXCL12 promotes CCR7 ligand-mediated breast cancer cell invasion and migration toward lymphatic vessels.

    CXCL12 promotes CCR7 ligand-mediated breast cancer cell invasion and migration toward lymphatic vessels.
    Hayasaka H, Yoshida J, Kuroda Y, Nishiguchi A, Matsusaki M, Kishimoto K, Nishimura H, Okada M, Shimomura Y, Kobayashi D, Shimazu Y, Taya Y, Akashi M, Miyasaka M., Free PMC Article

    04/30/2022
    lncRNA DARS-AS1 Promoted Osteosarcoma Progression through Regulating miR-532-3p/CCR7.

    lncRNA DARS-AS1 Promoted Osteosarcoma Progression through Regulating miR-532-3p/CCR7.
    Xue Y, Liu H, Nie G, Ren X., Free PMC Article

    04/23/2022
    C-C Chemokine Receptor 7 in Cancer.

    C-C Chemokine Receptor 7 in Cancer.
    Bill CA, Allen CM, Vines CM., Free PMC Article

    04/16/2022
    Mechanosensitive ACKR4 scavenges CCR7 chemokines to facilitate T cell de-adhesion and passive transport by flow in inflamed afferent lymphatics.

    Mechanosensitive ACKR4 scavenges CCR7 chemokines to facilitate T cell de-adhesion and passive transport by flow in inflamed afferent lymphatics.
    Friess MC, Kritikos I, Schineis P, Medina-Sanchez JD, Gkountidi AO, Vallone A, Sigmund EC, Schwitter C, Vranova M, Matti C, Arasa J, Saygili Demir C, Bovay E, Proulx ST, Tomura M, Rot A, Legler DF, Petrova TV, Halin C.

    02/26/2022
    Whole-blood CCR7 expression and chemoattraction in red blood cell alloimmunization.

    Whole-blood CCR7 expression and chemoattraction in red blood cell alloimmunization.
    Tamagne M, Pakdaman S, Bartolucci P, Habibi A, Galactéros F, Pirenne F, Vingert B.

    12/25/2021
    Immune signature of CCR7(+) central memory T cells associates with disease severity and Immunoglobulin E in bronchial asthma.

    Immune signature of CCR7(+) central memory T cells associates with disease severity and Immunoglobulin E in bronchial asthma.
    Moaaz M, Youssry S, Baess A, Abed A, Moaaz M.

    12/18/2021
    The C-terminal peptide of CCL21 drastically augments CCL21 activity through the dendritic cell lymph node homing receptor CCR7 by interaction with the receptor N-terminus.

    The C-terminal peptide of CCL21 drastically augments CCL21 activity through the dendritic cell lymph node homing receptor CCR7 by interaction with the receptor N-terminus.
    Jørgensen AS, Brandum EP, Mikkelsen JM, Orfin KA, Boilesen DR, Egerod KL, Moussouras NA, Vilhardt F, Kalinski P, Basse P, Chen YH, Yang Z, Dwinell MB, Volkman BF, Veldkamp CT, Holst PJ, Lahl K, Goth CK, Rosenkilde MM, Hjortø GM., Free PMC Article

    11/13/2021
    Cytoplasmic CCR7 (CCR7c) immunoexpression is associated with local tumor recurrence in triple-negative breast cancer.

    Cytoplasmic CCR7 (CCR7c) immunoexpression is associated with local tumor recurrence in triple-negative breast cancer.
    Gurgel DC, Wong DVT, Bandeira AM, Pereira JFB, Gomes-Filho JV, Pereira AC, Barros Silva PG, Távora FRF, Pereira AF, Lima-Júnior RCP, Almeida PRC.

    10/2/2021
    Clinical Significance of Chemokine Receptor CXCR4 and CCR7 mRNA Expression in Patients With Colorectal Cancer.

    Clinical Significance of Chemokine Receptor CXCR4 and CCR7 mRNA Expression in Patients With Colorectal Cancer.
    Nagasawa S, Tsuchida K, Shiozawa M, Hiroshima Y, Kimura Y, Hashimoto I, Watanabe H, Kano K, Numata M, Aoyama T, Sato S, Yamada T, Tamagawa H, Yamamoto N, Ogata T, Morinaga S, Yukawa N, Rino Y, Masuda M, Saeki H, Miyagi Y, Oshima T.

    09/11/2021
    Correlation between CXCR4, CXCR5 and CCR7 expression and survival outcomes in patients with clinical T1N0M0 non-small cell lung cancer.

    Correlation between CXCR4, CXCR5 and CCR7 expression and survival outcomes in patients with clinical T1N0M0 non-small cell lung cancer.
    Yue Z, Ningning D, Lin Y, Jianming Y, Hongtu Z, Ligong Y, Feng L, Shuaibo W, Yousheng M., Free PMC Article

    08/14/2021
    Lymphatic Metastasis of NSCLC Involves Chemotaxis Effects of Lymphatic Endothelial Cells through the CCR7-CCL21 Axis Modulated by TNF-alpha.

    Lymphatic Metastasis of NSCLC Involves Chemotaxis Effects of Lymphatic Endothelial Cells through the CCR7-CCL21 Axis Modulated by TNF-α.
    Zhang S, Wang H, Xu Z, Bai Y, Xu L., Free PMC Article

    07/31/2021
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