| Role of Calcr expressing neurons in the medial amygdala in social contact among females. | Role of Calcr expressing neurons in the medial amygdala in social contact among females.
Fukumitsu K, Huang AJ, McHugh TJ, Kuroda KO., Free PMC Article | 01/28/2023 |
| Calcitonin receptor signaling in the medial preoptic area enables risk-taking maternal care. | Calcitonin receptor signaling in the medial preoptic area enables risk-taking maternal care.
Yoshihara C, Tokita K, Maruyama T, Kaneko M, Tsuneoka Y, Fukumitsu K, Miyazawa E, Shinozuka K, Huang AJ, Nishimori K, McHugh TJ, Tanaka M, Itohara S, Touhara K, Miyamichi K, Kuroda KO. | 02/12/2022 |
| Paraventricular Calcitonin Receptor-Expressing Neurons Modulate Energy Homeostasis in Male Mice. | Paraventricular Calcitonin Receptor-Expressing Neurons Modulate Energy Homeostasis in Male Mice.
Gonzalez IE, Ramirez-Matias J, Lu C, Pan W, Zhu A, Myers MG, Olson DP., Free PMC Article | 10/9/2021 |
| The calcitonin receptor regulates osteocyte lacunae acidity during lactation in mice. | The calcitonin receptor regulates osteocyte lacunae acidity during lactation in mice.
Davey RA, Clarke MV, Golub SB, Russell PK, Zajac JD. | 07/31/2021 |
| Endosomal signaling of the CLR mediates pain transmission. | Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission.
Yarwood RE, Imlach WL, Lieu T, Veldhuis NA, Jensen DD, Klein Herenbrink C, Aurelio L, Cai Z, Christie MJ, Poole DP, Porter CJH, McLean P, Hicks GA, Geppetti P, Halls ML, Canals M, Bunnett NW., Free PMC Article | 06/23/2018 |
| calcitonin receptor is expressed in the suprachiasmatic nucleus and mediates body temperature fluctuations during the active phase in mice. | Calcitonin receptors are ancient modulators for rhythms of preferential temperature in insects and body temperature in mammals.
Goda T, Doi M, Umezaki Y, Murai I, Shimatani H, Chu ML, Nguyen VH, Okamura H, Hamada FN., Free PMC Article | 06/16/2018 |
| Calcr knockout resulted in abnormal quiescent state of muscle stem cells, reduction of their pool apoptosis and relocation from the MSC niche. | Calcitonin Receptor Signaling Inhibits Muscle Stem Cells from Escaping the Quiescent State and the Niche.
Yamaguchi M, Watanabe Y, Ohtani T, Uezumi A, Mikami N, Nakamura M, Sato T, Ikawa M, Hoshino M, Tsuchida K, Miyagoe-Suzuki Y, Tsujikawa K, Takeda S, Yamamoto H, Fukada S. | 08/6/2016 |
| data suggest that Clr-b modulation is a conserved innate host cell response to virus infection that is subverted by multiple CMV immune evasion strategies. | Modulation of Clr Ligand Expression and NKR-P1 Receptor Function during Murine Cytomegalovirus Infection.
Aguilar OA, Mesci A, Ma J, Chen P, Kirkham CL, Hundrieser J, Voigt S, Allan DS, Carlyle JR., Free PMC Article | 08/6/2016 |
| upregulated in synovial tissue of osteoarthritic mice by macrophage-derived IL-1 beta | Synovial macrophage-derived IL-1β regulates the calcitonin receptor in osteoarthritic mice.
Takano S, Uchida K, Miyagi M, Inoue G, Aikawa J, Fujimaki H, Minatani A, Sato M, Iwabuchi K, Takaso M., Free PMC Article | 06/28/2016 |
| protects the maternal skeleton during lactation by a direct action on osteocytes to inhibit osteolysis | A Role for the Calcitonin Receptor to Limit Bone Loss During Lactation in Female Mice by Inhibiting Osteocytic Osteolysis.
Clarke MV, Russell PK, Findlay DM, Sastra S, Anderson PH, Skinner JP, Atkins GJ, Zajac JD, Davey RA. | 11/21/2015 |
| Together, these data indicate that signaling through RAMP1 and CLR plays a role in mediating asthma pathology | Deficiency of RAMP1 attenuates antigen-induced airway hyperresponsiveness in mice.
Li M, Wetzel-Strong SE, Hua X, Tilley SL, Oswald E, Krummel MF, Caron KM., Free PMC Article | 11/7/2015 |
| The relevance of the OPG/RANK/RANKL system in the particle-induced osteolysis process, was investigated. | The role of calcitonin receptor signalling in polyethylene particle-induced osteolysis.
Neuerburg C, Wedemeyer C, Goedel J, Schlepper R, Hilken G, Schwindenhammer B, Schilling AF, Jäger M, Kauther MD. | 10/3/2015 |
| Nkrp1-Clr gene cluster appears to evolve more slowly relative to the related Ly49 cluster, and likely regulates innate immunosurveillance in a tissue-specific manner | Mouse Nkrp1-Clr gene cluster sequence and expression analyses reveal conservation of tissue-specific MHC-independent immunosurveillance.
Zhang Q, Rahim MM, Allan DS, Tu MM, Belanger S, Abou-Samra E, Ma J, Sekhon HS, Fairhead T, Zein HS, Carlyle JR, Anderson SK, Makrigiannis AP., Free PMC Article | 06/15/2013 |
| Odz4 is expressed in quiescent satellite cells, like calcitonin receptor, but the timing of the reappearance of these genes is different during regeneration. | Calcitonin receptor and Odz4 are differently expressed in Pax7-positive cells during skeletal muscle regeneration.
Yamaguchi M, Ogawa R, Watanabe Y, Uezumi A, Miyagoe-Suzuki Y, Tsujikawa K, Yamamoto H, Takeda S, Fukada S. | 04/6/2013 |
| The perinatal expression of CTR within the ENS suggests that the calcitonin/CTR system may have a role in the maturation of enteric neurons | Transient expression of the calcitonin receptor by enteric neurons of the embryonic and early post-natal mouse.
Wookey PJ, Turner K, Furness JB. | 10/20/2012 |
| CGRP-receptor component protein has been found to interact only with calcitonin-like receptor and represents a novel neuroendocrine regulatory step in calcitonin gene-related peptide signaling. | Direct interactions between calcitonin-like receptor (CLR) and CGRP-receptor component protein (RCP) regulate CGRP receptor signaling.
Egea SC, Dickerson IM., Free PMC Article | 07/14/2012 |
| CTR protects against hypercalcemia predominantly via its inhibitory action on osteoclasts. | The role of the calcitonin receptor in protecting against induced hypercalcemia is mediated via its actions in osteoclasts to inhibit bone resorption.
Turner AG, Tjahyono F, Chiu WS, Skinner J, Sawyer R, Moore AJ, Morris HA, Findlay DM, Zajac JD, Davey RA. | 05/7/2011 |
| Data show that amylin inactivation leads to a low bone mass due to an increase in bone resorption, whereas bone formation is unaffected. | Amylin inhibits bone resorption while the calcitonin receptor controls bone formation in vivo.
Dacquin R, Davey RA, Laplace C, Levasseur R, Morris HA, Goldring SR, Gebre-Medhin S, Galson DL, Zajac JD, Karsenty G., Free PMC Article | 09/27/2010 |
| These data provide strong evidence for a biological role of the CTR in regulating calcium homeostasis in states of calcium stress. | Calcitonin receptor plays a physiological role to protect against hypercalcemia in mice.
Davey RA, Turner AG, McManus JF, Chiu WS, Tjahyono F, Moore AJ, Atkins GJ, Anderson PH, Ma C, Glatt V, MacLean HE, Vincent C, Bouxsein M, Morris HA, Findlay DM, Zajac JD., Free PMC Article | 01/21/2010 |
| CTR is not only down regulated by signaling through the CTR but also by the peptides signaling through calcitonin receptor-like receptor, and receptor activity modifying proteins | Expression of the calcitonin receptor, calcitonin receptor-like receptor, and receptor activity modifying proteins during osteoclast differentiation.
Granholm S, Lundberg P, Lerner UH. | 01/21/2010 |
| Data show that mutation of calcitonin-like receptor did not affect its expression at the cell surface, but impaired the calcitonin gene-related peptide and adrenomedullin receptor function in the presence of receptor-activity-modifying proteins 1 and 2. | Aspartate(69) of the calcitonin-like receptor is required for its functional expression together with receptor-activity-modifying proteins 1 and -2.
Ittner LM, Luessi F, Koller D, Born W, Fischer JA, Muff R. | 01/21/2010 |
| AUF1 p40, HuR, and the 3'UTR of the CTR mRNA transcript could be involved in posttranscriptional regulation of CTR mRNA expression. | Interaction between 3' untranslated region of calcitonin receptor messenger ribonucleic acid (RNA) and adenylate/uridylate (AU)-rich element binding proteins (AU-rich RNA-binding factor 1 and Hu antigen R).
Yasuda S, Wada S, Arao Y, Kogawa M, Kayama F, Katayama S. | 01/21/2010 |
| Calcr is imprinted in a tissue-specific manner, with a predominant expression from the maternal allele in the brain | Calcr, a brain-specific imprinted mouse calcitonin receptor gene in the imprinted cluster of the proximal region of chromosome 6.
Hoshiya H, Meguro M, Kashiwagi A, Okita C, Oshimura M. | 01/21/2010 |