| Mouse S100G protein exhibits properties characteristic of a calcium sensor. | Mouse S100G protein exhibits properties characteristic of a calcium sensor.
Permyakov SE, Yundina EN, Kazakov AS, Permyakova ME, Uversky VN, Permyakov EA. | 06/5/2021 |
| Calbindin-D9k is a Novel Risk Gene for Neurodegenerative Disease. | Calbindin-D(9k) is a Novel Risk Gene for Neurodegenerative Disease.
Jung EM, Yoo YM, Park SY, Ahn C, Jeon BH, Hong EJ, Kim WY, Jeung EB. | 11/21/2020 |
| The results of this study show that CaBP-9k can protect pancreatic beta cell survival from ER stress and contribute to glucose homeostasis, which can reduce the risk of type 1 diabetes | The Protective Role of Calbindin-D(9k) on Endoplasmic Reticulum Stress-Induced Beta Cell Death.
Ahn C, Jung EM, An BS, Hong EJ, Yoo YM, Jeung EB., Free PMC Article | 04/4/2020 |
| this paper show that S100Gmay be an important anti-inflammatory mediator in fibroblasts following colitis induction | S100G expression and function in fibroblasts on colitis induction.
Ishiguro K, Watanabe O, Nakamura M, Yamamura T, Ando T, Goto H, Hirooka Y. | 04/8/2017 |
| These findings suggest that expression of paracellular tight junction genes is regulated by transcellular CaBP proteins, suggesting that active and passive calcium transport pathways may function cooperatively | Alteration of tight junction gene expression by calcium- and vitamin D-deficient diet in the duodenum of calbindin-null mice.
Hwang I, Yang H, Kang HS, Ahn C, Hong EJ, An BS, Jeung EB., Free PMC Article | 06/7/2014 |
| TRPV6, NCX1, and CaBP-9k in the fetal placenta and CaBP-28k in the maternal placenta may play key roles in controlling calcium transport across the placenta during pregnancy. | Calcium transport genes are differently regulated in maternal and fetal placenta in the knockout mice of calbindin-D(9k) and -D(28k).
Koo TH, Yang H, An BS, Choi KC, Hyun SH, Jeung EB. | 09/8/2012 |
| When immature mice were treated with 17beta-estradiol or progesterone for 3 days, we found that the expressions of Bax and caspase 3 protein were increased by estradiol treatment in WT and CaBP-9k KO mice. | Apoptosis- and endoplasmic reticulum stress-related genes were regulated by estrogen and progesterone in the uteri of calbindin-D(9k) and -D(28k) knockout mice.
Jung EM, An BS, Choi KC, Jeung EB. | 06/16/2012 |
| Ureteral obstruction leads to the alteration of renal vitamin D metabolic enzyme expression and calcium transporter abundance, which may secondarily induce the abnormality of vitamin D endocrine system and bone health. | Changes of renal vitamin D metabolic enzyme expression and calcium transporter abundance in obstructive nephropathy.
Zhang Y, Wu SY, Gu SS, Lv FK. | 03/10/2012 |
| These results indicate that deletion of CaBP-28k alone does not affect body calcium homeostasis, but that deletion of CaBP-9k and CaBP-28k has a significant effect on calcium processing under calcium-deficient conditions. | Effect of dietary calcium and 1,25-(OH)2D3 on the expression of calcium transport genes in calbindin-D9k and -D28k double knockout mice.
Ko SH, Choi KC, Oh GT, Jeung EB. | 01/21/2010 |
| PTHrP is an important regulator of fetal calcium homeostasis with its predominant effect being on unidirectional maternofetal transfer, probably mediated by modifying placental calbindin-D(9K) expression. | Increased maternofetal calcium flux in parathyroid hormone-related protein-null mice.
Bond H, Dilworth MR, Baker B, Cowley E, Requena Jimenez A, Boyd RD, Husain SM, Ward BS, Sibley CP, Glazier JD., Free PMC Article | 01/21/2010 |
| Depletion of the CaBP-9k gene in a KO mouse model had little phenotypic effect, suggesting that its depletion may be compensated for by calcium transporter genes in the intestine of young mice and in the kidney of adult mice. | Phenotype of a calbindin-D9k gene knockout is compensated for by the induction of other calcium transporter genes in a mouse model.
Lee GS, Lee KY, Choi KC, Ryu YH, Paik SG, Oh GT, Jeung EB. | 01/21/2010 |
| requirement for CaBPs during the early phase of embryo implantation | Endometrial calbindins are critical for embryo implantation: evidence from in vivo use of morpholino antisense oligonucleotides.
Luu KC, Nie GY, Salamonsen LA., Free PMC Article | 01/21/2010 |
| These results suggest that calcium regulates CaBP-D9k expression by modulating the circulating 1,25-dihydrxyvitamin D(3) level and that Vitamin D receptor is thus required for the dietary calcium-induced suppression of CaBP-D9k expression. | Vitamin D receptor is required for dietary calcium-induced repression of calbindin-D9k expression in mice.
Bolt MJ, Cao LP, Kong J, Sitrin MD, Li YC. | 01/21/2010 |
| Regulation of calbindin-D9k expression by 1,25-dihydroxyvitamin D(3) and parathyroid hormone in mouse primary renal tubular cells | Regulation of calbindin-D9k expression by 1,25-dihydroxyvitamin D(3) and parathyroid hormone in mouse primary renal tubular cells.
Cao LP, Bolt MJ, Wei M, Sitrin MD, Chun Li Y. | 01/21/2010 |
| Taken together, these results indicate that mouse CaBP-9k gene may be regulated by Dex in a tissue-specific manner, and reduced duodenal CaBP-9k via the GR pathway may take part in negative calcium absorption of GC-induced osteoporosis. | Glucocorticoids differentially regulate expression of duodenal and renal calbindin-D9k through glucocorticoid receptor-mediated pathway in mouse model.
Lee GS, Choi KC, Jeung EB. | 01/21/2010 |
| Results indicate that flutamide has an anti-progestogenic activity as a partial antagonist of progesterone in the regulation of uterine CaBP-9k in immature mouse model. | Anti-progestogenic effect of flutamide on uterine expression of calbindin-D9k mRNA and protein in immature mice.
Ji YK, Lee GS, Choi KC, Jeung EB. | 01/21/2010 |
| Data show tha calbindin D(9k) knockout mice are indistinguishable from wild-type mice in phenotype, are able to reproduce, and have normal serum calcium levels. | Calbindin D(9k) knockout mice are indistinguishable from wild-type mice in phenotype and serum calcium level.
Kutuzova GD, Akhter S, Christakos S, Vanhooke J, Kimmel-Jehan C, Deluca HF., Free PMC Article | 01/21/2010 |
| These results suggest that the mouse uterine calbindin-D9k gene is expressed under the control of a progesterone response element. | Transcriptional regulation of the mouse calbindin-D9k gene by the ovarian sex hormone.
Lee KY, Oh GT, Kang JH, Shin SM, Heo BE, Yun YW, Paik SG, Krisinger J, Leung PC, Jeung EB. | 01/21/2010 |
| Progesterone and its receptor may be dominant factors in the regulation of CaBP-9k but estrogen and ERalpha can influence the expression of the CaBP-9k gene via an indirect pathway in the uterus of immature mice. | Differential transcriptional and translational regulations of calbindin-D9k by steroid hormones and their receptors in the uterus of immature mice.
An BS, Choi KC, Hong EJ, Jung YW, Manabe N, Jeung EB. | 01/21/2010 |
| demonstrated that the CaBP-9k is distinctly regulated in the mouse placenta and extra-embryonic membrane, probably via sex steroid hormones (E2 and P4) and their receptors through a complex pathway | Complex regulation of Calbindin-D(9k) in the mouse placenta and extra-embryonic membrane during mid- and late pregnancy.
An BS, Choi KC, Lee GS, Leung PC, Jeung EB. | 01/21/2010 |