| DDR1-Induced Paracrine Factors of Hepatocytes Promote HSC Activation and Fibrosis Development. | DDR1-Induced Paracrine Factors of Hepatocytes Promote HSC Activation and Fibrosis Development.
Meng Y, Zhao T, Han T, Chen H, Zhang Z, Zhang D. | 11/27/2023 |
| Euphorbia factor L1 suppresses breast cancer liver metastasis via DDR1-mediated immune infiltration. | Euphorbia factor L1 suppresses breast cancer liver metastasis via DDR1-mediated immune infiltration.
Jiang D, Gao X, Tan R, Liu X, Zhu Y, Zhang L., Free PMC Article | 09/25/2023 |
| Evidence That DDR1 Promotes Oligodendrocyte Differentiation during Development and Myelin Repair after Injury. | Evidence That DDR1 Promotes Oligodendrocyte Differentiation during Development and Myelin Repair after Injury.
Mei R, Qiu W, Yang Y, Xu S, Rao Y, Li Q, Luo Y, Huang H, Yang A, Tao H, Qiu M, Zhao X., Free PMC Article | 07/7/2023 |
| Collagen-induced DDR1 upregulates CXCL5 to promote neutrophil extracellular traps formation and Treg infiltration in breast cancer. | Collagen-induced DDR1 upregulates CXCL5 to promote neutrophil extracellular traps formation and Treg infiltration in breast cancer.
Li H, Li J, Bai Z, Yan S, Li J. | 06/19/2023 |
| DDR1 activation in macrophage promotes IPF by regulating NLRP3 inflammasome and macrophage reaction. | DDR1 activation in macrophage promotes IPF by regulating NLRP3 inflammasome and macrophage reaction.
Wang H, Wen Y, Wang L, Wang J, Chen H, Chen J, Guan J, Xie S, Chen Q, Wang Y, Tao A, Du Y, Yan J. | 12/10/2022 |
| Deficiency in DDR1 Induces Pulmonary Hypertension and Impaired Alveolar Development. | Deficiency in DDR1 Induces Pulmonary Hypertension and Impaired Alveolar Development.
Bonafiglia QA, Zhou YQ, Hou G, Saha R, Hsu YR, Burke-Kleinman J, Bendeck MP. | 11/5/2022 |
| Collagenolysis-dependent DDR1 signalling dictates pancreatic cancer outcome. | Collagenolysis-dependent DDR1 signalling dictates pancreatic cancer outcome.
Su H, Yang F, Fu R, Trinh B, Sun N, Liu J, Kumar A, Baglieri J, Siruno J, Le M, Li Y, Dozier S, Nair A, Filliol A, Sinchai N, Rosenthal SB, Santini J, Metallo CM, Molina A, Schwabe RF, Lowy AM, Brenner D, Sun B, Karin M., Free PMC Article | 10/22/2022 |
| Discoidin domain receptor 1(DDR1) promote intestinal barrier disruption in Ulcerative Colitis through tight junction proteins degradation and epithelium apoptosis. | Discoidin domain receptor 1(DDR1) promote intestinal barrier disruption in Ulcerative Colitis through tight junction proteins degradation and epithelium apoptosis.
Li X, Li Q, Xiong B, Chen H, Wang X, Zhang D. | 09/24/2022 |
| Stiffness-responsive feedback autoregulation of DDR1 expression is mediated by a DDR1-YAP/TAZ axis. | Stiffness-responsive feedback autoregulation of DDR1 expression is mediated by a DDR1-YAP/TAZ axis.
Ngai D, Mohabeer AL, Mao A, Lino M, Bendeck MP. | 06/18/2022 |
| DDR1-induced neutrophil extracellular traps drive pancreatic cancer metastasis. | DDR1-induced neutrophil extracellular traps drive pancreatic cancer metastasis.
Deng J, Kang Y, Cheng CC, Li X, Dai B, Katz MH, Men T, Kim MP, Koay EA, Huang H, Brekken RA, Fleming JB., Free PMC Article | 03/26/2022 |
| DDR1 contributes to kidney inflammation and fibrosis by promoting the phosphorylation of BCR and STAT3. | DDR1 contributes to kidney inflammation and fibrosis by promoting the phosphorylation of BCR and STAT3.
Borza CM, Bolas G, Bock F, Zhang X, Akabogu FC, Zhang MZ, de Caestecker M, Yang M, Yang H, Lee E, Gewin L, Fogo AB, McDonald WH, Zent R, Pozzi A., Free PMC Article | 03/26/2022 |
| Tumour DDR1 promotes collagen fibre alignment to instigate immune exclusion. | Tumour DDR1 promotes collagen fibre alignment to instigate immune exclusion.
Sun X, Wu B, Chiang HC, Deng H, Zhang X, Xiong W, Liu J, Rozeboom AM, Harris BT, Blommaert E, Gomez A, Garcia RE, Zhou Y, Mitra P, Prevost M, Zhang D, Banik D, Isaacs C, Berry D, Lai C, Chaldekas K, Latham PS, Brantner CA, Popratiloff A, Jin VX, Zhang N, Hu Y, Pujana MA, Curiel TJ, An Z, Li R., Free PMC Article | 03/5/2022 |
| Discoidin domain receptor 1 activation links extracellular matrix to podocyte lipotoxicity in Alport syndrome. | Discoidin domain receptor 1 activation links extracellular matrix to podocyte lipotoxicity in Alport syndrome.
Kim JJ, David JM, Wilbon SS, Santos JV, Patel DM, Ahmad A, Mitrofanova A, Liu X, Mallela SK, Ducasa GM, Ge M, Sloan AJ, Al-Ali H, Boulina M, Mendez AJ, Contreras GN, Prunotto M, Sohail A, Fridman R, Miner JH, Merscher S, Fornoni A., Free PMC Article | 10/9/2021 |
| Discoidin Domain Receptor 1 is a therapeutic target for neurodegenerative diseases. | Discoidin Domain Receptor 1 is a therapeutic target for neurodegenerative diseases.
Fowler AJ, Hebron M, Balaraman K, Shi W, Missner AA, Greenzaid JD, Chiu TL, Ullman C, Weatherdon E, Duka V, Torres-Yaghi Y, Pagan FL, Liu X, Ressom H, Ahn J, Wolf C, Moussa C., Free PMC Article | 08/28/2021 |
| Tumor DDR1 deficiency reduces liver metastasis by colon carcinoma and impairs stromal reaction. | Tumor DDR1 deficiency reduces liver metastasis by colon carcinoma and impairs stromal reaction.
Romayor I, Márquez J, Benedicto A, Herrero A, Arteta B, Olaso E. | 07/31/2021 |
| Discoidin domain receptor 1-deletion ameliorates fibrosis and promotes adipose tissue beiging, brown fat activity, and increased metabolic rate in a mouse model of cardiometabolic disease. | Discoidin domain receptor 1-deletion ameliorates fibrosis and promotes adipose tissue beiging, brown fat activity, and increased metabolic rate in a mouse model of cardiometabolic disease.
Lino M, Ngai D, Liu A, Mohabeer A, Harper C, Caruso LL, Schroer SA, Fu F, McKee T, Giacca A, Woo M, Bendeck MP., Free PMC Article | 07/10/2021 |
| Expression of discoidin domain receptor 1 and E-cadherin in epidermis affects melanocyte behavior in rhododendrol-induced leukoderma mouse model. | Expression of discoidin domain receptor 1 and E-cadherin in epidermis affects melanocyte behavior in rhododendrol-induced leukoderma mouse model.
Abe Y, Hozumi Y, Okamura K, Suzuki T. | 06/19/2021 |
| MRIP Regulates the Myosin IIA Activity and DDR1 Function to Enable Collagen Tractional Remodeling. | MRIP Regulates the Myosin IIA Activity and DDR1 Function to Enable Collagen Tractional Remodeling.
Coelho NM, Wang A, Petrovic P, Wang Y, Lee W, McCulloch CA., Free PMC Article | 03/6/2021 |
| Discoidin Domain Receptor 1 Regulates Runx2 during Osteogenesis of Osteoblasts and Promotes Bone Ossification via Phosphorylation of p38. | Discoidin Domain Receptor 1 Regulates Runx2 during Osteogenesis of Osteoblasts and Promotes Bone Ossification via Phosphorylation of p38.
Chou LY, Chen CH, Chuang SC, Cheng TL, Lin YH, Chou HC, Fu YC, Wang YH, Wang CZ., Free PMC Article | 02/27/2021 |
| Discoidin Domain Receptors 1 Inhibition Alleviates Osteoarthritis via Enhancing Autophagy. | Discoidin Domain Receptors 1 Inhibition Alleviates Osteoarthritis via Enhancing Autophagy.
Chou HC, Chen CH, Chou LY, Cheng TL, Kang L, Chuang SC, Lin YS, Ho ML, Wang YH, Lin SY, Wang CZ., Free PMC Article | 02/27/2021 |
| DDR1 (Discoidin Domain Receptor-1)-RhoA (Ras Homolog Family Member A) Axis Senses Matrix Stiffness to Promote Vascular Calcification. | DDR1 (Discoidin Domain Receptor-1)-RhoA (Ras Homolog Family Member A) Axis Senses Matrix Stiffness to Promote Vascular Calcification.
Ngai D, Lino M, Rothenberg KE, Simmons CA, Fernandez-Gonzalez R, Bendeck MP., Free PMC Article | 10/10/2020 |
| Discoidin Domain Receptor 1 (DDR1) Is Necessary for Tissue Homeostasis in Pancreatic Injury and Pathogenesis of Pancreatic Ductal Adenocarcinoma. | Discoidin Domain Receptor 1 (DDR1) Is Necessary for Tissue Homeostasis in Pancreatic Injury and Pathogenesis of Pancreatic Ductal Adenocarcinoma.
Ruggeri JM, Franco-Barraza J, Sohail A, Zhang Y, Long D, Pasca di Magliano M, Cukierman E, Fridman R, Crawford HC., Free PMC Article | 08/22/2020 |
| DDR1 plays an important role in periodontal homeostasis and that absence of DDR1 predisposes mice to periodontal breakdown. | Loss of Discoidin Domain Receptor 1 Predisposes Mice to Periodontal Breakdown.
Chavez MB, Kolli TN, Tan MH, Zachariadou C, Wang C, Embree MC, Lira Dos Santos EJ, Nociti FH Jr, Wang Y, Tatakis DN, Agarwal G, Foster BL., Free PMC Article | 07/25/2020 |
| To the best of our knowledge, the results of the present study demonstrated for the first time that DDR1 expressed on the tumor cells promoted breast tumor growth by suppressing antitumor immunity. The present findings indicated that DDR1 may not only have a critical role in the progression of breast cancer, but may also serve as a potential therapeutic target for breast cancer, particularly Triplenegative breast cancer | DDR1 promotes breast tumor growth by suppressing antitumor immunity.
Zhong X, Zhang W, Sun T. | 04/4/2020 |
| In the clustering abilities and spatial distribution of DDR1b and DDR2. | Clustering, Spatial Distribution, and Phosphorylation of Discoidin Domain Receptors 1 and 2 in Response to Soluble Collagen I.
Yeung DA, Shanker N, Sohail A, Weiss BA, Wang C, Wellmerling J, Das S, Ganju RK, Miller JLC, Herr AB, Fridman R, Agarwal G., Free PMC Article | 03/7/2020 |