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    Bmp5 bone morphogenetic protein 5 [ Mus musculus (house mouse) ]

    Gene ID: 12160, updated on 18-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    BMP5 contributes to hepcidin regulation and systemic iron homeostasis in mice.

    BMP5 contributes to hepcidin regulation and systemic iron homeostasis in mice.
    Xiao X, Xu Y, Moschetta GA, Yu Y, Fisher AL, Alfaro-Magallanes VM, McMillen S, Phillips S, Wang CY, Christian J, Babitt JL., Free PMC Article

    11/3/2023
    Nesfatin-1 stimulates BMP5 expression and osteoclastogenesis in rheumatoid arthritis.

    Nesfatin-1 stimulates BMP5 expression and osteoclastogenesis in rheumatoid arthritis.
    Chang JW, Lin YY, Tsai CH, Liu SC, He XY, Wu YS, Huang CC, Tang CH.

    09/7/2023
    Changes in the Long Noncoding RNA Expression Profile in the Development of the Embryonic External Ear After BMP5 Gene Mutation.

    Changes in the Long Noncoding RNA Expression Profile in the Development of the Embryonic External Ear After BMP5 Gene Mutation.
    Liu W, Jin S, Lin L, Yang Q, Jiang H.

    07/24/2023
    Changes in the Transcriptome-Associated Co-Expression Profile of Embryonic External Ear Development After the BMP5 Gene Mutation.

    Changes in the Transcriptome-Associated Co-Expression Profile of Embryonic External Ear Development After the BMP5 Gene Mutation.
    Liu W, Lin L, Yang Q, Jin S, Jiang H.

    03/14/2023
    Bmp5 Mutation Alters mRNA Expression During External Ear Development.

    Bmp5 Mutation Alters mRNA Expression During External Ear Development.
    Liu W, Lin L, Sun Y, Jin S, Yang Q, Jiang H.

    03/14/2023
    BMP5 ameliorates diabetic peripheral neuropathy by augmenting mitochondrial function and inhibiting apoptosis in Schwann cells.

    BMP5 ameliorates diabetic peripheral neuropathy by augmenting mitochondrial function and inhibiting apoptosis in Schwann cells.
    Pang B, Zhang LL, Li B, Sun FX, Wang ZD.

    02/4/2023
    Bmp5 Mutation Alters miRNA Expression During Embryonic External Ear Development.

    Bmp5 Mutation Alters miRNA Expression During Embryonic External Ear Development.
    Liu W, Lin L, Jin S, Yang Q, Jiang H.

    11/26/2022
    Bmp5 Mutation Alters circRNA Expression During Embryonic External Ear Development.

    Bmp5 Mutation Alters circRNA Expression During Embryonic External Ear Development.
    Liu W, Lin L, Wang Q, Yang Q, Jiang H.

    09/10/2022
    BMP5 silencing inhibits chondrocyte senescence and apoptosis as well as osteoarthritis progression in mice.

    BMP5 silencing inhibits chondrocyte senescence and apoptosis as well as osteoarthritis progression in mice.
    Shao Y, Zhao C, Pan J, Zeng C, Zhang H, Liu L, Fan K, Liu X, Luo B, Fang H, Bai X, Zhang H, Cai D., Free PMC Article

    07/31/2021
    Data conclude that BMP-5 has stage-specific role to play during MC3T3E1 osteoblast differentiation in part by autocrine p38/Runx2/COLIA1 signaling.

    Bone morphogenetic protein-5, a key molecule that mediates differentiation in MC3T3E1 osteoblast cell line.
    Vijayan V, Gupta S, Gupta S.

    05/12/2018
    Bmp5 gene thus contains an "injury response" control region that is distinct from embryonic enhancers, and that is activated by multiple types of injury in adult animals

    A distinct regulatory region of the Bmp5 locus activates gene expression following adult bone fracture or soft tissue injury.
    Guenther CA, Wang Z, Li E, Tran MC, Logan CY, Nusse R, Pantalena-Filho L, Yang GP, Kingsley DM., Free PMC Article

    02/27/2016
    Early endothelial outgrowth cells act protective in diabetic nephropathy, and such effects are significantly stimulated by BMP-5

    eEOC-mediated modulation of endothelial autophagy, senescence, and EnMT in murine diabetic nephropathy.
    Patschan D, Schwarze K, Henze E, Becker JU, Patschan S, Müller GA.

    02/21/2015
    BMP-5 acts as a potent endothelial outgrowth cells agonist in murine AKI in the short and mid to long term

    Bone morphogenetic protein-5 and early endothelial outgrowth cells (eEOCs) in acute ischemic kidney injury (AKI) and 5/6-chronic kidney disease.
    Patschan D, Schwarze K, Lange A, Meise N, Henze E, Becker JU, Patschan S, Müller GA.

    10/19/2013
    Bone morphogenetic protein 5 regulates the number of keratinocyte stem cells from the skin of mice.

    Bone morphogenetic protein 5 regulates the number of keratinocyte stem cells from the skin of mice.
    Kangsamaksin T, Morris RJ.

    04/16/2011
    Data indicate that locus coeruleus development requires either Bmp5 or Bmp7, and one is able to compensate for the loss of the other.

    Bmp5/7 in concert with the mid-hindbrain organizer control development of noradrenergic locus coeruleus neurons.
    Tilleman H, Hakim V, Novikov O, Liser K, Nashelsky L, Di Salvio M, Krauthammer M, Scheffner O, Maor I, Mayseless O, Meir I, Kayam G, Sela-Donenfeld D, Simeone A, Brodski C.

    11/6/2010
    Variability in gene expression of BMP5 may be an important contributor to osteoarthritis genetic susceptibility

    Association of a functional microsatellite within intron 1 of the BMP5 gene with susceptibility to osteoarthritis.
    Wilkins JM, Southam L, Mustafa Z, Chapman K, Loughlin J., Free PMC Article

    02/1/2010
    Bmp5 is expressed in many skeletal precursors and different enhancers control expression in individual bones.

    Shaping skeletal growth by modular regulatory elements in the Bmp5 gene.
    Guenther C, Pantalena-Filho L, Kingsley DM., Free PMC Article

    01/21/2010
    BMP5 is required not only for skeletal patterning during embryonic development, but also for bone response and remodeling to mechanical stimulation at specific anatomic sites in the skeleton

    Dominant negative Bmp5 mutation reveals key role of BMPs in skeletal response to mechanical stimulation.
    Ho AM, Marker PC, Peng H, Quintero AJ, Kingsley DM, Huard J., Free PMC Article

    01/21/2010
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