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    Bcl2 B cell leukemia/lymphoma 2 [ Mus musculus (house mouse) ]

    Gene ID: 12043, updated on 5-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    H2S alleviated sepsis-induced acute kidney injury by inhibiting PERK/Bax-Bcl2 pathway.

    H(2)S alleviated sepsis-induced acute kidney injury by inhibiting PERK/Bax-Bcl2 pathway.
    Song C, Chen Q, Xu J, He K, Guo Q, Teng X, Xue H, Xiao L, Tian D, Jin S, An C, Wu Y.

    10/25/2024
    Anti-apoptotic protein Bcl-2 contributes to the determination of reserve cells during myogenic differentiation of C2C12 cells.

    Anti-apoptotic protein Bcl-2 contributes to the determination of reserve cells during myogenic differentiation of C2C12 cells.
    Nagata Y, Tomimori J, Hagiwara T.

    09/11/2024
    Low expression of miR-182 caused by DNA hypermethylation accelerates acute lymphocyte leukemia development by targeting PBX3 and BCL2: miR-182 promoter methylation is a predictive marker for hypomethylation agents + BCL2 inhibitor venetoclax.

    Low expression of miR-182 caused by DNA hypermethylation accelerates acute lymphocyte leukemia development by targeting PBX3 and BCL2: miR-182 promoter methylation is a predictive marker for hypomethylation agents + BCL2 inhibitor venetoclax.
    Li D, Yuan Y, Meng C, Lin Z, Zhao M, Shi L, Li M, Ye D, Cai Y, He X, Ye H, Zhou S, Zhou H, Gao S., Free PMC Article

    04/5/2024
    BCL-2 Modulates IRE1alpha Activation to Attenuate Endoplasmic Reticulum Stress and Pulmonary Fibrosis.

    BCL-2 Modulates IRE1α Activation to Attenuate Endoplasmic Reticulum Stress and Pulmonary Fibrosis.
    Le Saux CJ, Ho TC, Brumwell AM, Kathiriya JJ, Wei Y, Hughes JB, Garakani K, Atabai K, Auyeung VC, Papa FR, Chapman HA.,

    04/3/2024
    NELFA and BCL2 induce the 2C-like state in mouse embryonic stem cells in a chemically defined medium.

    NELFA and BCL2 induce the 2C-like state in mouse embryonic stem cells in a chemically defined medium.
    Wu B, Wang Y, Wei X, Zhang J, Wu J, Cao G, Zhang Y, Liu J, Li X, Bao S., Free PMC Article

    02/9/2024
    The TRIM21-FOXD1-BCL-2 axis underlies hyperglycaemic cell death and diabetic tissue damage.

    The TRIM21-FOXD1-BCL-2 axis underlies hyperglycaemic cell death and diabetic tissue damage.
    Cheng W, Cai C, Xu Y, Xiao X, Shi T, Liao Y, Wang X, Chen S, Zhou M, Liao Z., Free PMC Article

    12/20/2023
    BCL2 is a major regulator of haploidy maintenance in murine embryonic stem cells.

    BCL2 is a major regulator of haploidy maintenance in murine embryonic stem cells.
    Sun S, Zhao Q, Zhao Y, Geng M, Wang Q, Gao Q, Zhang XO, Zhang W, Shuai L., Free PMC Article

    12/15/2023
    Neuronal survival factor TAFA2 suppresses apoptosis through binding to ADGRL1 and activating cAMP/PKA/CREB/BCL2 signaling pathway.

    Neuronal survival factor TAFA2 suppresses apoptosis through binding to ADGRL1 and activating cAMP/PKA/CREB/BCL2 signaling pathway.
    Liang H, Tang LY, Ge HY, Chen MM, Lu SY, Zhang HX, Shen CL, Shen Y, Fei J, Wang ZG.

    11/30/2023
    CircTLK1 alleviates oxygen-glucose deprivation/reperfusion induced apoptosis in HK-2 cells through miR-136-5p/Bcl2 signal axis.

    CircTLK1 alleviates oxygen-glucose deprivation/reperfusion induced apoptosis in HK-2 cells through miR-136-5p/Bcl2 signal axis.
    Kuang L, Lu A, Yao S., Free PMC Article

    07/25/2023
    MicroRNA-202-5p-dependent inhibition of Bcl-2 contributes to macrophage apoptosis and atherosclerotic plaque formation.

    MicroRNA-202-5p-dependent inhibition of Bcl-2 contributes to macrophage apoptosis and atherosclerotic plaque formation.
    Xu F, Yao F, Ning Y.

    04/26/2023
    Long noncoding RNA HOTAIR facilitates pulmonary vascular endothelial cell apoptosis via DNMT1 mediated hypermethylation of Bcl-2 promoter in COPD.

    Long noncoding RNA HOTAIR facilitates pulmonary vascular endothelial cell apoptosis via DNMT1 mediated hypermethylation of Bcl-2 promoter in COPD.
    Dai Z, Liu X, Zeng H, Chen Y., Free PMC Article

    12/24/2022
    Hadh deficiency induced oligoasthenoteratozoospermia through the TNF-alpha/Bcl-2 pathway in male mice.

    Hadh deficiency induced oligoasthenoteratozoospermia through the TNF-α/Bcl-2 pathway in male mice.
    Zhu H, Wang H, Cheng Y, Liu D, Zhang A, Wen Z, Gao J.

    12/3/2022
    Microplastics and di (2-ethylhexyl) phthalate synergistically induce apoptosis in mouse pancreas through the GRP78/CHOP/Bcl-2 pathway activated by oxidative stress.

    Microplastics and di (2-ethylhexyl) phthalate synergistically induce apoptosis in mouse pancreas through the GRP78/CHOP/Bcl-2 pathway activated by oxidative stress.
    Wang Y, Zhang Y, Sun X, Shi X, Xu S.

    08/27/2022
    BCL-2 isoform beta promotes angiogenesis by TRiC-mediated upregulation of VEGF-A in lymphoma.

    BCL-2 isoform β promotes angiogenesis by TRiC-mediated upregulation of VEGF-A in lymphoma.
    Hang X, Zhao L, Wu B, Li S, Liu P, Xu J, Wang X, Chi P, Chen C, Niu T, Dai L, Liu Y.

    07/16/2022
    LncRNA SNHG1 promotes sepsis-induced myocardial injury by inhibiting Bcl-2 expression via DNMT1.

    LncRNA SNHG1 promotes sepsis-induced myocardial injury by inhibiting Bcl-2 expression via DNMT1.
    Zhang R, Niu Z, Liu J, Dang X, Feng H, Sun J, Pan L, Peng Z., Free PMC Article

    07/16/2022
    Phosphorylation of BCL2 at the Ser70 site mediates RANKL-induced osteoclast precursor autophagy and osteoclastogenesis.

    Phosphorylation of BCL2 at the Ser70 site mediates RANKL-induced osteoclast precursor autophagy and osteoclastogenesis.
    Ke D, Yu Y, Li C, Han J, Xu J., Free PMC Article

    04/9/2022
    MiR-21 participates in LPS-induced myocardial injury by targeting Bcl-2 and CDK6.

    MiR-21 participates in LPS-induced myocardial injury by targeting Bcl-2 and CDK6.
    Li Y, Sun G, Wang L.

    04/2/2022
    Bcl-2 Is Necessary to Counteract Bim and Promote Survival of TCRalphabeta(+)CD8alphaalpha(+) Intraepithelial Lymphocyte Precursors in the Thymus.

    Bcl-2 Is Necessary to Counteract Bim and Promote Survival of TCRαβ(+)CD8αα(+) Intraepithelial Lymphocyte Precursors in the Thymus.
    Shanmuganad S, Hummel SA, Varghese V, Hildeman DA., Free PMC Article

    02/12/2022
    Effects of low intensity pulsed ultrasound on expression of B-cell lymphoma-2 and BCL2-Associated X in premature ovarian failure mice induced by 4-vinylcyclohexene diepoxide.

    Effects of low intensity pulsed ultrasound on expression of B-cell lymphoma-2 and BCL2-Associated X in premature ovarian failure mice induced by 4-vinylcyclohexene diepoxide.
    Xu H, Xia Y, Qin J, Xu J, Li C, Wang Y., Free PMC Article

    01/1/2022
    HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways.

    HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways.
    Miyamoto R, Kanai A, Okuda H, Komata Y, Takahashi S, Matsui H, Inaba T, Yokoyama A., Free PMC Article

    11/13/2021
    The anti-apoptotic Bcl-2 protein regulates hair follicle stem cell function.

    The anti-apoptotic Bcl-2 protein regulates hair follicle stem cell function.
    Geueke A, Mantellato G, Kuester F, Schettina P, Nelles M, Seeger JM, Kashkar H, Niemann C., Free PMC Article

    10/30/2021
    Toxoplasma gondii ROP17 promotes autophagy via the Bcl-2-Beclin 1 pathway.

    Toxoplasma gondii ROP17 promotes autophagy via the Bcl-2-Beclin 1 pathway.
    Guo M, Sun J, Wang WT, Liu HY, Liu YH, Qin KR, Hu JR, Li XY, Liu HL, Wang W, Chen ZY, Wang CF, Wang HL.

    10/2/2021
    Loss-of-function of Fbxo10, encoding a post-translational regulator of BCL2 in lymphomas, has no discernible effect on BCL2 or B lymphocyte accumulation in mice.

    Loss-of-function of Fbxo10, encoding a post-translational regulator of BCL2 in lymphomas, has no discernible effect on BCL2 or B lymphocyte accumulation in mice.
    Masle-Farquhar E, Russell A, Li Y, Zhu F, Rui L, Brink R, Goodnow CC., Free PMC Article

    09/18/2021
    Postmortem expression of apoptosis-related genes in the liver of mice and their use for estimation of the time of death.

    Postmortem expression of apoptosis-related genes in the liver of mice and their use for estimation of the time of death.
    Noshy PA.

    09/11/2021
    Differential expression of Bax-Bcl-2 and PARP-1 confirms apoptosis of EAC cells in Swiss albino mice by Morus laevigata.

    Differential expression of Bax-Bcl-2 and PARP-1 confirms apoptosis of EAC cells in Swiss albino mice by Morus laevigata.
    Rahi MS, Islam MS, Jerin I, Jahangir CA, Hasan MM, Hoque KMF, Reza MA.

    08/7/2021
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