| Contribution of ADD3 and the HLA Genes to Biliary Atresia Risk in Chinese. | Contribution of ADD3 and the HLA Genes to Biliary Atresia Risk in Chinese.
Cui MM, Gong YM, Pan WH, Pei HY, Bai MR, Song HL, Han XR, Wu WJ, Yu WW, Gu BL, Cai W, Zhou Y, Chu X., Free PMC Article | 11/28/2023 |
| Knockdown of long noncoding RNA SAN rejuvenates aged adipose-derived stem cells via miR-143-3p/ADD3 axis. | Knockdown of long noncoding RNA SAN rejuvenates aged adipose-derived stem cells via miR-143-3p/ADD3 axis.
Xiong H, Ren S, Chen J, Yang X, Liu Y, Xu Z, Guo J, Jiang T, Yuan M, Liu Y, Zhang G, Li W, Machens HG, Chen Z., Free PMC Article | 08/25/2023 |
| The correlation between rs2501577 gene polymorphism and biliary atresia: a systematic review and meta-analysis. | The correlation between rs2501577 gene polymorphism and biliary atresia: a systematic review and meta-analysis.
Li TF, Ke XY, Zhang YR, Zhan JH. | 08/23/2023 |
| Posttranscriptional inhibition of gamma-adducin promotes the proliferation and migration of osteosarcoma cells. | Posttranscriptional inhibition of γ-adducin promotes the proliferation and migration of osteosarcoma cells.
Suo Z, Ma X, Ding Y, Zhou Y, Duan X, Fei L, Song J, Ding H. | 11/29/2022 |
| QKI-5 regulates the alternative splicing of cytoskeletal gene ADD3 in lung cancer. | QKI-5 regulates the alternative splicing of cytoskeletal gene ADD3 in lung cancer.
Wang JZ, Fu X, Fang Z, Liu H, Zong FY, Zhu H, Yu YF, Zhang XY, Wang SF, Huang Y, Hui J., Free PMC Article | 02/19/2022 |
| Identification of New Genetic Clusters in Glioblastoma Multiforme: EGFR Status and ADD3 Losses Influence Prognosis. | Identification of New Genetic Clusters in Glioblastoma Multiforme: EGFR Status and ADD3 Losses Influence Prognosis.
Navarro L, San-Miguel T, Megías J, Santonja N, Calabuig S, Muñoz-Hidalgo L, Roldán P, Cerdá-Nicolás M, López-Ginés C., Free PMC Article | 06/19/2021 |
| Association of common variation in ADD3 and GPC1 with biliary atresia susceptibility. | Association of common variation in ADD3 and GPC1 with biliary atresia susceptibility.
Bai MR, Niu WB, Zhou Y, Gong YM, Lu YJ, Yu XX, Wei ZL, Wu W, Song HL, Yu WW, Gu BL, Cai W, Chu X., Free PMC Article | 02/27/2021 |
| Increased expression of phosphorylated adducin in tumor cells. | Increased expression of phosphorylated adducin in tumor cells.
Luo C, Wang G, Ying H, Shen J, Gilligan DM., Free PMC Article | 01/9/2021 |
| Loss of cytoskeleton protein ADD3 promotes tumor growth and angiogenesis in glioblastoma multiforme. | Loss of cytoskeleton protein ADD3 promotes tumor growth and angiogenesis in glioblastoma multiforme.
Kiang KM, Zhang P, Li N, Zhu Z, Jin L, Leung GK. | 12/19/2020 |
| The intragenic epistatic association of ADD3 with biliary atresia in Southern Han Chinese population has been reported. | The intragenic epistatic association of ADD3 with biliary atresia in Southern Han Chinese population.
Wang Z, Xie X, Zhao J, Fu M, Li Y, Zhong W, Xia H, Zhang Y, Zhang RZ., Free PMC Article | 03/9/2019 |
| ADD3 and ADD3-AS1 variants increased susceptibility to BA, suggesting that these genes may play an additive role in the pathogenesis of the disease. | Single nucleotide polymorphisms within Adducin 3 and Adducin 3 antisense RNA1 genes are associated with biliary atresia in Thai infants.
Laochareonsuk W, Chiengkriwate P, Sangkhathat S. | 09/15/2018 |
| Data indicate lysine acetyltransferase 2B (KAT2B) as a susceptibility gene for kidney and heart disease in adducin 3 (gamma) protein (ADD3)-associated disorders. | A homozygous KAT2B variant modulates the clinical phenotype of ADD3 deficiency in humans and flies.
Gonçalves S, Patat J, Guida MC, Lachaussée N, Arrondel C, Helmstädter M, Boyer O, Gribouval O, Gubler MC, Mollet G, Rio M, Charbit M, Bole-Feysot C, Nitschke P, Huber TB, Wheeler PG, Haynes D, Juusola J, Billette de Villemeur T, Nava C, Afenjar A, Keren B, Bodmer R, Antignac C, Simons M., Free PMC Article | 06/30/2018 |
| MiR-145-5p was confirmed to target ADD3 by luciferase reporter assay. The downregulation of miR-145 may contribute to liver fibrosis in Biliary atresia by upregulating the expression of ADD3. | Downregulation of microRNA-145 may contribute to liver fibrosis in biliary atresia by targeting ADD3.
Ye Y, Li Z, Feng Q, Chen Z, Wu Z, Wang J, Ye X, Zhang D, Liu L, Gao W, Zhang L, Wang B., Free PMC Article | 11/4/2017 |
| ADD3 gene deletion is associated with acute lymphoblastic leukemia. | Characterisation of the genomic landscape of CRLF2-rearranged acute lymphoblastic leukemia.
Russell LJ, Jones L, Enshaei A, Tonin S, Ryan SL, Eswaran J, Nakjang S, Papaemmanuil E, Tubio JM, Fielding AK, Vora A, Campbell PJ, Moorman AV, Harrison CJ., Free PMC Article | 07/22/2017 |
| ADD3 gene plays an important role in biliary atresia pathogenesis. | Association between single nucleotide polymorphisms in the ADD3 gene and susceptibility to biliary atresia.
Zeng S, Sun P, Chen Z, Mao J, Wang J, Wang B, Liu L., Free PMC Article | 06/20/2015 |
| Common genetic variants in 10q24.2 can alter biliary atresia risk by regulating ADD3 expression levels in the liver, and may exert an effect on disease epidemiology and on the general population. | Common genetic variants regulating ADD3 gene expression alter biliary atresia risk.
Cheng G, Tang CS, Wong EH, Cheng WW, So MT, Miao X, Zhang R, Cui L, Liu X, Ngan ES, Lui VC, Chung PH, Chan IH, Liu J, Zhong W, Xia H, Yu J, Qiu X, Wu XZ, Wang B, Dong X, Tou J, Huang L, Yi B, Ren H, Chan EK, Ye K, O'Reilly PF, Wong KK, Sham PC, Cherny SS, Tam PK, Garcia-Barceló MM. | 10/4/2014 |
| High expression of ADD3 is associated with glioma. | MiR-145 functions as a tumor-suppressive RNA by targeting Sox9 and adducin 3 in human glioma cells.
Rani SB, Rathod SS, Karthik S, Kaur N, Muzumdar D, Shiras AS., Free PMC Article | 05/3/2014 |
| ADD3 gene may be functionally relevant for the development of biliary atresia | Replication of a GWAS signal in a Caucasian population implicates ADD3 in susceptibility to biliary atresia.
Tsai EA, Grochowski CM, Loomes KM, Bessho K, Hakonarson H, Bezerra JA, Russo PA, Haber BA, Spinner NB, Devoto M., Free PMC Article | 05/3/2014 |
| Homozygous p.G367D mutation in ADD3 causes spastic diplegic/quadriplegic cerebral palsy and intellectual disability. | Mutations in γ adducin are associated with inherited cerebral palsy.
Kruer MC, Jepperson T, Dutta S, Steiner RD, Cottenie E, Sanford L, Merkens M, Russman BS, Blasco PA, Fan G, Pollock J, Green S, Woltjer RL, Mooney C, Kretzschmar D, Paisán-Ruiz C, Houlden H., Free PMC Article | 03/22/2014 |
| gamma-adducin may influence blood pressure homeostasis by modulating renal NaCl transport. | γ-Adducin stimulates the thiazide-sensitive NaCl cotransporter.
Dimke H, San-Cristobal P, de Graaf M, Lenders JW, Deinum J, Hoenderop JG, Bindels RJ., Free PMC Article | 06/18/2011 |
| These findings suggest novel roles for adducins in stabilization of epithelial junctions and regulation of junctional remodeling. | Adducins regulate remodeling of apical junctions in human epithelial cells.
Naydenov NG, Ivanov AI., Free PMC Article | 03/19/2011 |
| Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators., Free PMC Article | 09/15/2010 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| In ADD1 GlyGly homozygotes, the properties of the brachial artery are related to the ADD3 (A386G) polymorphism, but the underlying mechanism needs further clarification. | Arterial properties in relation to genetic variations in the adducin subunits in a white population.
Seidlerová J, Staessen JA, Bochud M, Nawrot T, Casamassima N, Citterio L, Kuznetsova T, Jin Y, Manunta P, Richart T, Struijker-Boudier HA, Fagard R, Filipovský J, Bianchi G, Seidlerová J, Staessen JA, Bochud M, Nawrot T, Casamassima N, Citterio L, Kuznetsova T, Jin Y, Manunta P, Richart T, Struijker-Boudier HA, Fagard R, Filipovský J, Bianchi G. | 01/21/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (4) articlesGene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium. Arterial properties in relation to genetic variations in the adducin subunits in a white population.
Seidlerová J, Staessen JA, Bochud M, Nawrot T, Casamassima N, Citterio L, Kuznetsova T, Jin Y, Manunta P, Richart T, Struijker-Boudier HA, Fagard R, Filipovský J, Bianchi G, Seidlerová J, Staessen JA, Bochud M, Nawrot T, Casamassima N, Citterio L, Kuznetsova T, Jin Y, Manunta P, Richart T, Struijker-Boudier HA, Fagard R, Filipovský J, Bianchi G. Gly460Trp alpha-adducin mutation as a possible mechanism leading to endolymphatic hydrops in Ménière's syndrome.
Teggi R, Lanzani C, Zagato L, Delli Carpini S, Manunta P, Bianchi G, Bussi M. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
Grupe A, Li Y, Rowland C, Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell TJ, Cherny S, Doil L, Tacey K, van Luchene R, Myers A, Wavrant-De Vrièze F, Kaleem M, Hollingworth P, Jehu L, Foy C, Archer N, Hamilton G, Holmans P, Morris CM, Catanese J, Sninsky J, White TJ, Powell J, Hardy J, O'Donovan M, Lovestone S, Jones L, Morris JC, Thal L, Owen M, Williams J, Goate A. | 08/13/2008 |