| Eosinophil-derived galectin-10 upregulates matrix metalloproteinase expression in bullous pemphigoid blisters. | Eosinophil-derived galectin-10 upregulates matrix metalloproteinase expression in bullous pemphigoid blisters.
Sato T, Chiba T, Nakahara T, Watanabe K, Sakai S, Noguchi N, Noto M, Ueki S, Kono M. | 12/1/2023 |
| Glutathione disrupts galectin-10 Charcot-Leyden crystal formation to possibly ameliorate eosinophil-based diseases such as asthma. | Glutathione disrupts galectin-10 Charcot-Leyden crystal formation to possibly ameliorate eosinophil-based diseases such as asthma.
Na H, Sayed H, Ayala GJ, Wang X, Liu Y, Yu J, Liu T, Mayo KH, Su J., Free PMC Article | 05/17/2023 |
| Behcet syndrome: The disturbed balance between anti- (CLEC12A, CLC) and proinflammatory (IFI27) gene expressions. | Behçet syndrome: The disturbed balance between anti- (CLEC12A, CLC) and proinflammatory (IFI27) gene expressions.
Oğuz AK, Oygür ÇŞ, Taşır S, Özdağ H, Akar MN., Free PMC Article | 05/1/2023 |
| Galectin-10 as a Potential Biomarker for Eosinophilic Diseases. | Galectin-10 as a Potential Biomarker for Eosinophilic Diseases.
Tomizawa H, Yamada Y, Arima M, Miyabe Y, Fukuchi M, Hikichi H, Melo RCN, Yamada T, Ueki S., Free PMC Article | 11/5/2022 |
| Crystalline State Determines the Potency of Galectin-10 Protein Assembly to Induce Inflammation. | Crystalline State Determines the Potency of Galectin-10 Protein Assembly to Induce Inflammation.
Zhao Y, Mo S, Yu L, Li X, Hao Y, Zhang W, Zhang Q, Wang P, Wang X, Wang C, Zhang L. | 04/23/2022 |
| Chronic rhinosinusitis with nasal polyposis (CRSwNP): the correlation between expression of Galectin-10 and Clinical-Cytological Grading (CCG). | Chronic rhinosinusitis with nasal polyposis (CRSwNP): the correlation between expression of Galectin-10 and Clinical-Cytological Grading (CCG).
Gelardi M, Netti GS, Giancaspro R, Spadaccino F, Pennella A, Fiore V, La Gatta E, Grilli GM, Cassano M, Ranieri E. | 02/5/2022 |
| Identification of galectin10 as a biomarker for periodontitis based on proteomic analysis of gingival crevicular fluid. | Identification of galectin‑10 as a biomarker for periodontitis based on proteomic analysis of gingival crevicular fluid.
Kim JS, Cho IH, Kim KH, Hwang YS. | 05/8/2021 |
| [Expression and pathological role of galectin-10 in different types of nasal polyps]. | [Expression and pathological role of galectin-10 in different types of nasal polyps].
Li CH, Liu X, Wu WX, Wang YJ, Ai YF, Liu HB. | 12/12/2020 |
| Galectin-10, the protein that forms Charcot-Leyden crystals, is not stored in granules but resides in the peripheral cytoplasm of human eosinophils. | Galectin-10, the protein that forms Charcot-Leyden crystals, is not stored in granules but resides in the peripheral cytoplasm of human eosinophils.
Melo RCN, Wang H, Silva TP, Imoto Y, Fujieda S, Fukuchi M, Miyabe Y, Hirokawa M, Ueki S, Weller PF., Free PMC Article | 12/5/2020 |
| Increased CLC/Gal-10 and MBP-1 levels in the sputum were strongly correlated with sputum eosinophils in patients with asthma. CLC/Gal-10 and MBP-1 may be useful biomarkers for differentiation of eosinophilic airway inflammation in asthma. | Charcot-Leyden crystal protein/galectin-10 is a surrogate biomarker of eosinophilic airway inflammation in asthma.
Nyenhuis SM, Alumkal P, Du J, Maybruck BT, Vinicky M, Ackerman SJ., Free PMC Article | 05/30/2020 |
| CLC mRNA levels based on the qRT-PCR may serve as a reliable and alternative method for the identification of eosinophilic chronic rhinosinusitis with nasal polyps | Predictive Significance of Charcot-Leyden Crystals for Eosinophilic Chronic Rhinosinusitis With Nasal Polyps.
Liu C, Yan B, Qi S, Zhang Y, Zhang L, Wang C. | 05/9/2020 |
| Because Trp72 is the highly conserved in the ligand binding sites of galectins, we used EGFP-tagged W72A to show that Gal-10 could not be transported into the nucleus, indicating that Trp72 is crucial for Gal-10 transport into that organelle. | Identification of key amino acid residues determining ligand binding specificity, homodimerization and cellular distribution of human galectin-10.
Su J, Song C, Si Y, Cui L, Yang T, Li Y, Wang H, Tai G, Zhou Y. | 03/30/2019 |
| findings show that galectin-10 functions as a T cell-suppressive molecule in eosinophils | Regulatory Eosinophils Suppress T Cells Partly through Galectin-10.
Lingblom C, Andersson J, Andersson K, Wennerås C. | 09/30/2017 |
| The results support the potential for galectin-10 to be used as a surrogate biomarker of eosinophilic airway inflammation. | Galectin-10, a potential biomarker of eosinophilic airway inflammation.
Chua JC, Douglass JA, Gillman A, O'Hehir RE, Meeusen EN., Free PMC Article | 01/12/2013 |
| CLC and IFNAR1 were identified to be overall differentially expressed between early- and late-onset CRC, and are important in the development of early-onset CRC. | CLC and IFNAR1 are differentially expressed and a global immunity score is distinct between early- and late-onset colorectal cancer.
Ågesen TH, Berg M, Clancy T, Thiis-Evensen E, Cekaite L, Lind GE, Nesland JM, Bakka A, Mala T, Hauss HJ, Fetveit T, Vatn MH, Hovig E, Nesbakken A, Lothe RA, Skotheim RI. | 05/5/2012 |
| DK-PGD-induced CLC/Gal-10 mRNA level can serve as a potential marker for monitoring pharmacodynamic effects of blood exposure to CRTH2 modulating agents | The mRNA level of Charcot-Leyden crystal protein/galectin-10 is a marker for CRTH2 activation in human whole blood in vitro.
Lin TA, Kourteva G, Hilton H, Li H, Tare NS, Carvajal V, Hang JS, Wei X, Renzetti LM. | 02/26/2011 |
| Genetic variation in Charcot-Leyden crystal protein was found to be associated with allergic rhinitis | CLC- a novel susceptibility gene for allergic rhinitis?
Bryborn M, Halldén C, Säll T, Cardell LO, Bryborn M, Halldén C, Säll T, Cardell LO. | 03/8/2010 |
| Data show that galectin-10 expression was related to the histological grade and with the number of eosinophils in the lesion. | Galectin-10, eosinophils, and celiac disease.
De Re V, Simula MP, Cannizzaro R, Pavan A, De Zorzi MA, Toffoli G, Canzonieri V. | 01/21/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (2) articlesNew genetic associations detected in a host response study to hepatitis B vaccine.
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M. CLC- a novel susceptibility gene for allergic rhinitis?
Bryborn M, Halldén C, Säll T, Cardell LO, Bryborn M, Halldén C, Säll T, Cardell LO. | 08/12/2009 |
| expressed in human T lymphocytes, galectin-10 is essential for the functional properties of CD25(+) Treg cells. | Human CD4+CD25+ regulatory T cells: proteome analysis identifies galectin-10 as a novel marker essential for their anergy and suppressive function.
Kubach J, Lutter P, Bopp T, Stoll S, Becker C, Huter E, Richter C, Weingarten P, Warger T, Knop J, Müllner S, Wijdenes J, Schild H, Schmitt E, Jonuleit H. | 01/21/2010 |
| The five genes, and three of the encoded proteins, were shown differentially expressed between a group of keratoconus patients and a reference group using different techniques | Altered expression of CLC, DSG3, EMP3, S100A2, and SLPI in corneal epithelium from keratoconus patients.
Nielsen K, Heegaard S, Vorum H, Birkenkamp-Demtröder K, Ehlers N, Orntoft TF. | 01/21/2010 |
| Downregulated in whole blood of infants hospitalised with respiratory syncytial virus (RSV), subtype B, bronchiolitis. | Whole blood gene expression in infants with respiratory syncytial virus bronchiolitis.
Fjaerli HO, Bukholm G, Krog A, Skjaeret C, Holden M, Nakstad B., Free PMC Article | 01/21/2010 |
| downregulated significantly in acute myeloid leukemia patients whose white blood cell count was higher than 100 x 10(9)/L cells | Overexpression of translocation-associated fusion genes of FGFRI, MYC, NPMI, and DEK, but absence of the translocations in acute myeloid leukemia. A microarray analysis.
Larramendy ML, Niini T, Elonen E, Nagy B, Ollila J, Vihinen M, Knuutila S. | 01/21/2010 |
| Changes in the expressions of galectin-10 are potentially important for myeloid cell differentiation into specific lineages. | Potential roles of galectins in myeloid differentiation into three different lineages.
Abedin MJ, Kashio Y, Seki M, Nakamura K, Hirashima M. | 01/21/2010 |