| Influence of Interleukin-2 and Brain-Derived Neurotrophic Factor (BDNF) on the Size of Myocardial Infarction in Rats with Systemic Inflammatory Response. | Influence of Interleukin-2 and Brain-Derived Neurotrophic Factor (BDNF) on the Size of Myocardial Infarction in Rats with Systemic Inflammatory Response.
Burovenko IY, Sonin DL, Borshcheva OV, Istomina MS, Zaitseva EA, Protsak ES, Borshchev VY, Borshchev YY, Galagudza MM. | 09/8/2023 |
| Addition of 320 (48) and 640 (96) mg/L (mg/kg BW) boron markedly reduced the serum IgG concentrations; splenic IL-2 and IL-10 expression; the number of CD3(+), CD4(+) and PCNA(+) cells; and increased the number of splenic CD8(+) and caspase-3(+) cells and promoted caspase-3 expression in CD3(+) cells. | Boron Affects Immune Function Through Modulation of Splenic T Lymphocyte Subsets, Cytokine Secretion, and Lymphocyte Proliferation and Apoptosis in Rats.
Jin E, Li S, Ren M, Hu Q, Gu Y, Li K. | 01/27/2018 |
| Data show that the ratio of peripheral blood CD4(+)/CD8(+) T lymphocytes and the levels of connexin-40 (Cx40), interleukins IL-2, IL-4 and IL-6 are significantly elevated in SH rats. | [An increase in the ratio of peripheral blood CD4+/CD8+ T lymphocytes and the levels of connexin 40 and inflammatory factors in spontaneously hypertensive rats].
Wang A, Zhang H, Zhang L, Li X, Li L, Si J, Ma K. | 07/30/2016 |
| Data indicate that C-rel binding on the interleukin-2 (IL-2) promoter region declined in the aged CD4+T cells. | Decreased c-rel activation contributes to aberrant interleukin-2 expression in CD4(+)T cells of aged rats.
Gong Z, Liu T, Wan Y, Hang Z, Tong X, Zhang B, Yang H, Zhang X, Zhang L, Jin G. | 08/16/2014 |
| our findings indicate a generic and robust stress-induced reduction in plasma IL-12 | In vivo suppression of plasma IL-12 levels by acute and chronic stress paradigms: potential mediating mechanisms and sex differences.
Shaashua L, Sominsky L, Levi B, Sorski L, Reznick M, Page GG, Ben-Eliyahu S., Free PMC Article | 11/24/2012 |
| PDIA3 might be potentially involve into the occurence and development of acute rejection response in renal transplantation and increased plasma IL-2, IL-4, IL-6, and CRP levels play an important role to prevent acute kidney allograft rejection in rats. | PDIA3 mRNA expression and IL-2, IL-4, IL-6, and CRP levels of acute kidney allograft rejection in rat.
Chen G, Mi J, Xiao MZ, Fu YR. | 07/14/2012 |
| Effects of systemic IL-2 on neurotransmission in several cortical areas is measured by in-vivo microdialysis; IL-2 has dose-dependent effects on depressive-related behavior after delayed but not acute testing, but no effects on anxiety-like behavior. | Time-dependent in-vivo effects of interleukin-2 on neurotransmitters in various cortices: relationships with depressive-related and anxiety-like behaviour.
Karrenbauer BD, Müller CP, Ho YJ, Spanagel R, Huston JP, Schwarting RK, Pawlak CR. | 10/22/2011 |
| The purpose of this study was to evaluate the effect of exhaustive exercise on proteins associated with muscle damage and regeneration, including IL-2, IL-4 and MyoD in muscle and adipose tissue. | Acute exhaustive exercise regulates IL-2, IL-4 and MyoD in skeletal muscle but not adipose tissue in rats.
Rosa Neto JC, Lira FS, Zanchi NE, Oyama LM, Pimentel GD, Santos RV, Seelaender M, Oller do Nascimento CM., Free PMC Article | 09/24/2011 |
| IL-2 neuroprotective action upon retinal ganglion cells in vitro is mediated by Janus kinase and extracellular signal-regulated kinase 1/2 activation. | Protein kinases JAK and ERK mediate protective effect of interleukin-2 upon ganglion cells of the developing rat retina.
Marra C, Gomes Moret D, de Souza Corrêa A, Chagas da Silva F, Moraes P, Linden R, Sholl-Franco A. | 06/18/2011 |
| In a living cell imaging study, treatment with IL-2 at different concentrations during development of cultured hippocampal neurons induces major changes in dendritic branches, filopodia mobility, and spine density. | Interleukin-2 enhances dendritic development and spinogenesis in cultured hippocampal neurons.
Shen Y, Liu SS, Zhan MY, Luo JH, Zhu LJ. | 01/1/2011 |
| Immunoregulatory cytokines belonging to the Th-1 group (IL-2 and IFN-gamma) were increased in the retina of experimental diabetic rats | IL-2 and IFN-gamma in the retina of diabetic rats.
Johnsen-Soriano S, Sancho-Tello M, Arnal E, Navea A, Cervera E, Bosch-Morell F, Miranda M, Javier Romero F. | 09/13/2010 |
| The pIL-2-shRNA interference plasmid could decrease proinflammatory cytokine production of T lymphocytes and protect hepatocytes from apoptosis in allografts. | Knockdown of interleukin-2 by shRNA-mediated RNA interference prolongs liver allograft survival.
Chen Y, Yan T, Shi LJ, Liu Z, Liang SY, Luan XF, Long FW, Chen J, Peng Y, Yan LN, Gong JP. | 03/29/2010 |
| IL-2 may participate in the immune rejection in allogeneic liver transplantation. | [Implication of different expression of IL-2 mRNA and IL-10 mRNA in CD4(+)CD25(+)T cell induced immune tolerance of liver transplantation in rat].
Shi LB, Zhang HW, Cui YY. | 02/8/2010 |
| CD4+CD25+ T cells alloactivated ex vivo by IL-2 or IL-4 become potent alloantigen-specific inhibitors of rejection with different phenotypes, suggesting separate pathways of activation by Th1 and Th2 responses. | CD4+CD25+ T cells alloactivated ex vivo by IL-2 or IL-4 become potent alloantigen-specific inhibitors of rejection with different phenotypes, suggesting separate pathways of activation by Th1 and Th2 responses.
Verma ND, Plain KM, Nomura M, Tran GT, Robinson C, Boyd R, Hodgkinson SJ, Hall BM. | 01/21/2010 |
| Data show that inescapable and escapable stressors have different effects on behavior in the modified active avoidance test and on IL-2 levels in brain areas that are known to be involved in emotional processes. | Effects of escapable and inescapable stressors on behavior and interleukin-2 in the brain.
Lee YT, Wang WF, Cheng CW, Wu SL, Pawlak CR, Ho YJ. | 01/21/2010 |
| Data suggest that estradiol effects on T cell IFN-gamma abd IL-2 production afer trauma-hemorrhage are mediated via non-genomic pathway, and which is in turn mediated via ERK, p38, and JNK pathways. | Mitogen activated protein kinase (MAPK) mediates non-genomic pathway of estrogen on T cell cytokine production following trauma-hemorrhage.
Suzuki T, Yu HP, Hsieh YC, Choudhry MA, Bland KI, Chaudry IH., Free PMC Article | 01/21/2010 |
| IL-2/IL-10, sFas and Fas are expressed in intestinal mucosa in rats with acute necrotizing pancreati | Dynamic changes of IL-2/IL-10, sFas and expression of Fas in intestinal mucosa in rats with acute necrotizing pancreatitis.
Dang SC, Zhang JX, Qu JG, Mao ZF, Wang XQ, Zhu B., Free PMC Article | 01/21/2010 |
| Cell activation in hypothalamus correlated with decreases in the quantity of IL-2-positive cells. | Comparative analysis of the expression of c-Fos and interleukin-2 proteins in hypothalamus cells during various treatments.
Barabanova SV, Artyukhina ZE, Ovchinnikova KT, Abramova TV, Kazakova TB, Khavinson VKh, Malinin VV, Korneva EA. | 01/21/2010 |
| hypothalamic IL2 is decreased after intranasal administration of Epithalon | Interleukin-2 concentration in hypothalamic structures of rats receiving peptides during mild stress.
Barabanova SV, Artyukhina ZE, Kazakova TB, Khavinson VKh, Malinin VV, Korneva EA. | 01/21/2010 |
| Analysis of murine CD28 mutants reveals a correlation between translocation to lipid rafts and costimulation of IL-2 production. | Translocation of CD28 to lipid rafts and costimulation of IL-2.
Sadra A, Cinek T, Imboden JB., Free PMC Article | 01/21/2010 |
| These results provide new evidence indicating that cytokine mRNA in the brain can be related to elevated plus-maze behavior and that this relationship is site (prefrontal cortex, striatum)- and cytokine mRNA-specific (IL-2). | Cytokine mRNA levels in brain and peripheral tissues of the rat: relationships with plus-maze behavior.
Pawlak CR, Schwarting RK, Bauhofer A. | 01/21/2010 |
| stress-induced increase in serum IL-6 level and decrease in IL-2 level | The effect of compound nutrients on stress-induced changes in serum IL-2, IL-6 and TNF-alpha levels in rats.
Liu YL, Bi H, Chi SM, Fan R, Wang YM, Ma XL, Chen YM, Luo WJ, Pei JM, Chen JY. | 01/21/2010 |
| effects of IL-2 on contraction and the [Ca2+]i transient of ventricular myocytes are mediated via the cardiac kappa opioid receptor. | Opioid receptor-mediated effects of interleukin-2 on the [Ca2+]i transient and contraction in isolated ventricular myocytes of the rat.
Cao CM, Xia Q, Chen YY, Zhang X, Shen YL. | 01/21/2010 |
| IL-1alpha and IL-2 produce an increase of glucose metabolism in uteri isolated from underfed rats | Effect of interleukin 1alpha and interleukin 2 over glucose metabolism in isolated uterus of restricted diet rats. Influence of NO and COX-2.
Linares JA, Campos ML, Goldraij A. | 01/21/2010 |