| Noncoding rare variants in PANX3 are associated with chronic back pain. | Noncoding rare variants in PANX3 are associated with chronic back pain.
Belonogova NM, Kirichenko AV, Freidin MB, Williams FMK, Suri P, Aulchenko YS, Axenovich TI, Tsepilov YA., Free PMC Article | 03/24/2023 |
| Influence of the three-dimensional culture of human bone marrow mesenchymal stromal cells within a macroporous polysaccharides scaffold on Pannexin 1 and Pannexin 3. | Influence of the three-dimensional culture of human bone marrow mesenchymal stromal cells within a macroporous polysaccharides scaffold on Pannexin 1 and Pannexin 3.
Guerrero J, Oliveira H, Aid R, Bareille R, Siadous R, Letourneur D, Mao Y, Kohn J, Amédée J. | 11/16/2019 |
| All three pannexins Panx1, Panx2, and Panx3 mRNAs were expressed in all of the analyzed undifferentiated stem cell lines. | Human stem cells express pannexins.
Hainz N, Beckmann A, Schubert M, Haase A, Martin U, Tschernig T, Meier C., Free PMC Article | 08/18/2018 |
| Panx3 was upregulated during osteogenic differentiation in a time-dependent manner. Panx3 overexpression promoted osteogenic differentiation of human dental pulp-derived mesenchymal stromal cells, whereas depletion of Panx3 resulted in a decline of differentiation. | The Role of Pannexin3-Modified Human Dental Pulp-Derived Mesenchymal Stromal Cells in Repairing Rat Cranial Critical-Sized Bone Defects.
Song F, Sun H, Huang L, Fu D, Huang C. | 03/17/2018 |
| Panx3 channels regulate the proliferation, differentiation, and fusion of skeletal muscle myoblasts. (Review) | Regulation of Skeletal Muscle Myoblast Differentiation and Proliferation by Pannexins.
Langlois S, Cowan KN. | 09/9/2017 |
| Panx3 has a defensive role in dental pulp inflammation. | Pannexin3 inhibits TNF-α-induced inflammatory response by suppressing NF-κB signalling pathway in human dental pulp cells.
Song F, Sun H, Wang Y, Yang H, Huang L, Fu D, Gan J, Huang C., Free PMC Article | 07/22/2017 |
| The results of this study do not support a major contribution of PANX1-3 to disease risk of schizophrenia according to DSM-5. | The role of Pannexin gene variants in schizophrenia: systematic analysis of phenotypes.
Gawlik M, Wagner M, Pfuhlmann B, Stöber G. | 02/4/2017 |
| Case Report: osteosarcomatous transformation of axillary sweat gland neoplasm with high PANX3 expression. | High Relative Expression of Pannexin 3 (PANX3) in an Axillary Sweat Gland Carcinoma With Osteosarcomatous Transformation.
Romano RC, Gardner JM, Shalin SC, Ram R, Govindarajan R, Montgomery CO, Gilley JH, Nicholas RW. | 01/28/2017 |
| Panx3 hemichannel is expressed in human odontoblast-like cells and mediates ATP release into the extracellular space. | Expression of Pannexin3 in human odontoblast-like cells and its hemichannel function in mediating ATP release.
Fu D, Song F, Sun H, Pei D, Wang Y, Lei J, Huang C. | 08/20/2016 |
| Panx1 and Panx3 are co-expressed in human skeletal muscle myoblasts and play a pivotal role in dictating the proliferation and differentiation. | Pannexin 1 and pannexin 3 channels regulate skeletal muscle myoblast proliferation and differentiation.
Langlois S, Xiang X, Young K, Cowan BJ, Penuela S, Cowan KN., Free PMC Article | 01/3/2015 |
| Data suggest that both up-regulation and down-regulation of expression of pannexins (PANX1, PANX2, PANX3) are associated with disease onset and/or progression; examples include neoplasms, multiple sclerosis, migraine, and hypertension. [REVIEW] | Pannexin channels and their links to human disease.
Penuela S, Harland L, Simek J, Laird DW. | 09/27/2014 |
| The 70 kDa immunoreactive species of Panx3 highly regulated during keratinocyte differentiation was shown to most likely correspond to another Panx3 isoform. | Pannexin1 and Pannexin3 exhibit distinct localization patterns in human skin appendages and are regulated during keratinocyte differentiation and carcinogenesis.
Cowan KN, Langlois S, Penuela S, Cowan BJ, Laird DW. | 01/26/2013 |
| Panx3 functions to switch the chondrocyte cell fate from proliferation to differentiation by regulating the intracellular ATP/cAMP levels | Pannexin 3 regulates intracellular ATP/cAMP levels and promotes chondrocyte differentiation.
Iwamoto T, Nakamura T, Doyle A, Ishikawa M, de Vega S, Fukumoto S, Yamada Y., Free PMC Article | 07/5/2010 |
| although Panx1 and Panx3 share a common endoplasmic reticulum to Golgi secretory pathway to Cx43, their ultimate cell surface residency appears to be independent of cell contacts and the need for intact microtubules | Pannexin1 and pannexin3 delivery, cell surface dynamics, and cytoskeletal interactions.
Bhalla-Gehi R, Penuela S, Churko JM, Shao Q, Laird DW., Free PMC Article | 04/19/2010 |
| These studies show that Panx1 and Panx3 have many characteristics that are distinct from Cx43 and that these proteins probably play an important biological role as single membrane channels. | Pannexin 1 and pannexin 3 are glycoproteins that exhibit many distinct characteristics from the connexin family of gap junction proteins.
Penuela S, Bhalla R, Gong XQ, Cowan KN, Celetti SJ, Cowan BJ, Bai D, Shao Q, Laird DW. | 01/21/2010 |